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이경건(Kyounggun Lee),조정아(Jungah Cho),이민호(Min-Ho Lee),정석원(Suk-Won Jung),이국녕(Kook-Nyung Lee),김유래(Yu-Rae Kim),백창욱(Chang-Wook Baek),성우경(Woo-Kyeong Seong) 대한전기학회 2010 대한전기학회 학술대회 논문집 Vol.2010 No.7
본 논문에서는 당뇨병 검출을 위한 당 센서의 제작을 보고하였다. 마이크로 머시닝 공법을 통하여 웨이퍼 레벨로 전극이 제작되었으며, 표면 처리 기술을 이용하여 당 산화 효소의 흡착을 하였다. 당 산화 효소와 당이 반응하여 발생 시키는 과산화 수소를 측정함으로써 당의 농도를 측정할 수 있었다. 작업 전극에 0.7 (vs. Ag/AgCl)의 전위를 인가하였을 때, 5 mM의 PBS 기반의 당 용액에서 ~250 ㎁, 35 mM 용액에서 ~600 ㎁가 흐르는 것으로 측정되었다. 제작된 센서의 평가를 위하여 당 농도에 대하여 실시간 측정이 성공적으로 이루어져 센서로서의 가능성을 보았다. 또한 웨이퍼 레벨의 제작을 통하여 상용화의 가능성을 볼 수 있었다.
Germanium Silicon Alloy Anode Material Capable of Tunable Overpotential by Nanoscale Si Segregation
Kim, Hyungki,Son, Yoonkook,Park, Chibeom,Lee, Min-Joon,Hong, Misun,Kim, Jungah,Lee, Minkyung,Cho, Jaephil,Choi, Hee Cheul American Chemical Society 2015 NANO LETTERS Vol.15 No.6
<P>We developed the novel electrode that enables fine control of overpotential by exploiting surface segregation that is the enrichment of one component at the surface of binary alloy. To realize this approach, we controlled the proportion of Si with low Li diffusivity at the surface by annealing the SiGe nanowire in H<SUB>2</SUB> environment at various temperatures. The resulting SiGe nanowires annealed at 850 °C exhibited high reversible capacity (>1031 mA·h·g<SUP>–1</SUP>), and long cycle life (400 cycles) with high capacity retention (89.0%) at 0.2 C. This superior battery performance is attributed to the remaining unlithiated part acting as support frame to prevent pulverization of anode material, which results from the fine-tuning of overpotential by controlling the degree of Si segregation.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/nalefd/2015/nalefd.2015.15.issue-6/acs.nanolett.5b01257/production/images/medium/nl-2015-012577_0008.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nl5b01257'>ACS Electronic Supporting Info</A></P>
JungJin Kim,ChiUn Pae,MiRan Kim,JungAh Min,KyungHee Kim,ChangUk Lee,Chul Lee,InHo Paik 대한신경정신의학회 2010 PSYCHIATRY INVESTIGATION Vol.7 No.3
Post-menopausal women experience variable biological and psychological changes. The effect of reduced levels of estrogen can effect on post-menopausal depression. Estrogen triggers physiological responses by binding to the estrogen receptor (ER). Two subtypes of ER, ERa and ERb are now known. We investigated the significance of ERa and ERb polymorphisms and post-menopasal depression in this study. Forty three women with post-menopausal depression and 63 post-menopausal women without depression as normal controls were recruited. Polymerase chain reaction-restriction fragment length polymorphism method was used to investigate genotypes of ERa and ERb polymorphisms. Genotypes of PvuII and XbaI polymorphism of ERa receptor were significantly different in patients with post-menopausal depression comparing with controls. Genotypes of ERb did not show association with post-menopausal depression. Our study showed that ERa receptor polymorphism had an association with depression in post-menopausal women. It suggests that investigation of ER genes and their functions might be important for understanding pathophysilogical mechanism of post-menopausal depression.