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Zheng Yanqiong,Peng Junbiao,Tang Jie,Li Weiguang,Chen Juncong,Wang Chao,Zhang Jianhua,Wei Bin,Li Xifeng 한국물리학회 2021 Current Applied Physics Vol.22 No.-
The mixed cohosts of electron transport host (E-host): 4,40-bis(carbazol-9-yl)biphenyl (CBP) have been comparatively investigated for an efficient green fluorescent organic light emitting diode (OLED) doped with a thermally activated delayed fluorescence (TADF) emitter (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile (4CzIPN). The E-host:CBP systems significantly enhance the electroluminescent (EL) properties. After doping Ehost, the lifetime of the emissive layer decreases and the surface becomes smoother, together with the impedance decreases for one magnitude and the hole-injection depresses. The charge balance and improved interface both contribute to the EL performance enhancement. Here we develop a universal mixed host system suitable to most of emitters.
FNC inhibits non-small cell lung cancer by activating the mitochondrial apoptosis pathway
Jing Xiang,Niu Shuai,Liang Yi,Chen Huiping,Wang Ning,Peng Youmei,Ma Fang,Yue Wanying,Wang Qingduan,Chang Junbiao,Zhang Yi,Zhang Yan 한국유전학회 2022 Genes & Genomics Vol.44 No.1
Background: Previously, we published that 4'-azid-2'-deoxy-2'-fluorarabinoside (FNC), a novel cytosine nucleoside analog, has good anti-viral and anti-tumor activity. Objective: This study aimed to further explore the role and molecular mechanism of FNC in non-small cell lung cancer (NSCLC). Methods: FNC was tested in the NSCLC H460 cell line, the Lewis mouse model, and the H460 cell xenograft model. The effects of FNC were assessed by cell viability, transwell migration, and wound scratch analyses of cell migration and invasion. Apoptosis was assessed by flow cytometry. Proteins expression was assessed by western blot and immunohistochemistry staining (IHC). Results: FNC inhibits the proliferation and metastasis of H460 cells in a time- and dose-dependent manner. FNC treatment showed efficacy and low toxicity in the Lewis mouse lung cancer model as well as in the H460 cell xenograft model. Further, FNC induced H460 cell apoptosis through the activation of the mitochondrial pathway. Notably, FNC inhibited invasion by increasing E-cadherin protein and reducing the protein expression of VEGF, MMP-2, MMP-9, and CD31. Conclusion: FNC inhibits NSCLC by activating the mitochondrial apoptosis pathway and regulating the expressions of multiple proteins related to cell adhesion and invasion, highlighting its potential as an NSCLC therapeutic.
High-performance hybrid white organic light-emitting diodes employing p-type interlayers
Baiquan Liu,Hong Tao,Jianhua Zou,Miao Xu,Dongyu Gao,Linfeng Lan,Lei Wang,Honglong Ning,Junbiao Peng 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.27 No.-
A simplified hybrid white organic light-emitting diode (WOLED) employing a p-type interlayer isdesigned, simultaneously realizing high efficiency, high color rendering index (CRI), low efficiency roll-off, low voltage and stable color. The device exhibits maximum total efficiencies of 29.8 cd/A and20.9 lm/W, which slightly decrease to 28.6 cd/A and 16.5 lm/W even at a high luminance of 5000 cd/m2. Besides, a slight color-shift and a CRI of 85 at 100 cd/m2 (3.65 V) are obtained. Such superior resultssystematically demonstrate that the use of p-type interlayer is a new way to realize high-performancehybrid WOLEDs.
Baiquan Liu,Honglong Ning,Lei Wang,Jianhua Zou,Zhongwei Zhou,Miao Xu,Hong Tao,Dongyu Gao,Linfeng Lan,Junbiao Peng 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.30 No.-
An efficient single-emitting layer hybrid white organic light-emitting diode (WOLED) was developed,simultaneously fulfilling low efficiency roll-off, stable color and extreme luminance. At the practicalluminance of 1000 cd/m2, a total current efficiency of 42.8 cd/A and power efficiency of 19.2 lm/W areachieved, maintaining as high as 40.5 cd/A and 15.5 lm/W even at 5000 cd/m2. Besides, a slight colorvariation [(0.025, 0.011)] and extreme luminance ( 106 cd/m2) are obtained. The working mechanism isunveiled and it is demonstrated that the triplet-exciton-confining ability of electron transport layersplays a more vital role in device performances, particularly for the lifetime.
A metal oxide TFT gate driver with a single negative power source employing a boosting module
Yangang Xu,Jun-Wei Chen,Wen-Xing Xu,Lei Zhou,Wei-Jing Wu,Jianhua Zou,Miao Xu,Lei Wang,Junbiao Peng 한국정보디스플레이학회 2020 Journal of information display Vol.21 No.1
This paper presents a new gate driver integrated by In-Zn-O thin-film transistors (IZO TFTs) with the etch stop layer (ESL) structure, in which only a single negative power source is used on account of a new boosting module. The boosting module is controlled only by the VIN signal for generating a lower level than VSS. The proposed gate driver with 15 stages is fabricated through the IZO TFT process on a glass substrate to verify its function. The experiment results showed that the proposed gate driver can successfully output full-swing waveforms with resistive load RL=2 kΩ and capacitive load CL=30 pF at the 16.7 and 66.7 kHz clock frequencies, and can also output as small as 3.2 μs pulse width with little distortion, revealing good stability.