Preliminary analysis on cancer mortality and morbidity of TCE exposed workers in Korea

Juhwan Noh,Dong-Hee Koh,Jae-Yong Shin,Suk-Yong Jang,Hae-Ahn Lee,Eun-Cheol Park,Jin-Ha Yoon,Yeon Soon Ahn 환경독성보건학회 2015 한국독성학회 심포지움 및 학술발표회 Vol.2015 No.6

The environmental burden of lung cancer attributable to indoor radon exposure in Korea

Juhwan Noh(노주환),Jungwoo Sohn(손정우),Heeseon Jang(장희선),Seong-Kyung Cho(조성경),Yun Tae Kim(김윤태),Eung Joo Park(박응주),Dae Ryong Kang(강대용),Dong Chun Shin(신동천),Changsoo Kim(김창수) 환경독성보건학회 2018 한국독성학회 심포지움 및 학술발표회 Vol.2018 No.6

Residential radon and environmental burden of disease among Non-smokers

Juhwan Noh,Jungwoo Sohn,Jaelim Cho,Dae Ryong Kang,Sowon Joo,Changsoo Kim,Dong Chun Shin 대한직업환경의학회 2016 대한직업환경의학회지 Vol.28 No.-

Background: Lung cancer was the second highest absolute cancer incidence globally and the first cause of cancer mortality in 2014. Indoor radon is the second leading risk factor of lung cancer after cigarette smoking among ever smokers and the first among non-smokers. Environmental burden of disease (EBD) attributable to residential radon among non-smokers is critical for identifying threats to population health and planning health policy. Methods: To identify and retrieve literatures describing environmental burden of lung cancer attributable to residential radon, we searched databases including Ovid-MEDLINE, -EMBASE from 1980 to 2016. Search terms included patient keywords using ‘lung’ , ‘neoplasm’ , exposure keywords using ‘residential’ , ‘radon’ , and outcomes keywords using ‘years of life lost’ , ‘years of life lost due to disability’ , ‘burden’. Searching through literatures identified 261 documents; further 9 documents were identified using manual searching. Two researchers independently assessed 271 abstracts eligible for inclusion at the abstract level. Full text reviews were conducted for selected publications after the first assessment. Ten studies were included in the final evaluation. Review: Global disability‐adjusted life years (DALYs)(95 % uncertainty interval) for lung cancer were increased by 35.9 % from 23,850,000(18,835,000-29,845,000) in 1900 to 32,405,000(24,400,000-38,334,000) in 2000. DALYs attributable to residential radon were 2,114,000(273,000-4,660,000) DALYs in 2010. Lung cancer caused 34,732,900(33,042,600 ~ 36,328,100) DALYs in 2013. DALYs attributable to residential radon were 1,979,000(1,331,000-2,768,000) DALYs for in 2013. The number of attributable lung cancer cases was 70-900 and EBD for radon was 1,000-14,000 DALYs in Netherland. The years of life lost were 0.066 years among never-smokers and 0.198 years among ever-smoker population in Canada. Conclusion: In summary, estimated global EBD attributable to residential radon was 1,979,000 DALYs for both sexes in 2013. In Netherlands, EBD for radon was 1,000–14,000 DALYs. Smoking population lost three times more years than never-smokers in Canada. There was no study estimating EBD of residential radon among never smokers in Korea and Asian country. In addition, there were a few studies reflecting the age of building, though residential radon exposure level depends on the age of building. Further EBD study reflecting Korean disability weight and the age of building is required to estimate EBD precisely.

Prevalence of Comorbidity among People with Hypertension: The Korea National Health and Nutrition Examination Survey 2007-2013

Juhwan Noh,김현창,Anna Shin,Hyungseon Yeom,Suk-Yong Jang,Jung Hyun Lee,김창수,서일 대한심장학회 2016 Korean Circulation Journal Vol.46 No.5

Background and Objectives: Joint National Committee guidelines attempt to vary treatment recommendations for patients based on considerations of their comorbidities. The aim of the present study is to estimate the age-standardized prevalence of common comorbidities among Korean hypertension patients. Subjects and Methods: We analyzed the Korea National Health and Nutrition Examination Survey from 2007 to 2013. Among the 58423 participants, 30092 adults, aged ≥30 yrs who completed a health examination and interview survey, were selected. The survey procedures were used to estimate weighted prevalence and odds ratios for 8 comorbidities, including obesity, diabetes mellitus, dyslipidemia, cardiovascular disease, chronic kidney disease, and thyroid disease. Results: Most chronic conditions were more prevalent in adults with hypertension than in those without hypertension. Common comorbidities were obesity (60.1%), dyslipidemia (57.6%), and impaired fasting glucose (45.1%). Hypertensive patients with two or more comorbid diseases were 42.2% and those with three or more diseases were 17.7%. The age- and sex-specific prevalence of three or more comorbid diseases among male hypertension patients was significantly higher than those patients in the 30-59 (p<0.05) age group. Conclusion: Comorbidity is highly prevalent in Korean patients with hypertension.

Active learning with non- <i>ab initio</i> input features toward efficient CO ₂ reduction catalysts

Noh, Juhwan,Back, Seoin,Kim, Jaehoon,Jung, Yousung Royal Society of Chemistry 2018 Chemical Science Vol.9 No.23

<▼1><P>In this work, we propose the use of the d-band width of the muffin-tin orbital theory (to account for the local coordination environment) plus electronegativity (to account for adsorbate renormalization) as a simple set of alternative descriptors for chemisorption which do not require <I>ab initio</I> calculations for large-scale first-hand screening.</P></▼1><▼2><P>In a conventional chemisorption model, the d-band center theory (augmented sometimes with the upper edge of the d-band for improved accuracy) plays a central role in predicting adsorption energies and catalytic activity as a function of the d-band center of solid surfaces, but it requires density functional calculations that can be quite costly for the purposes of large scale screening of materials. In this work, we propose to use the d-band width of the muffin-tin orbital theory (to account for the local coordination environment) plus electronegativity (to account for adsorbate renormalization) as a simple set of alternative descriptors for chemisorption which do not require <I>ab initio</I> calculations for large-scale first-hand screening. This pair of descriptors is then combined with machine learning methods, namely, neural network (NN) and kernel ridge regression (KRR). We show, for a toy set of 263 alloy systems, that the CO adsorption energy on the (100) facet can be predicted with a mean absolute deviation error of 0.05 eV. We achieved this high accuracy by utilizing an active learning algorithm, without which the accuracy was 0.18 eV. In addition, the results of testing the method with other facets such as (111) terrace and (211) step sites suggest that the present model is also capable of handling different coordination environments effectively. As an example of the practical application of this machine, we identified Cu<SUB>3</SUB>Y@Cu* as an active and cost-effective electrochemical CO<SUB>2</SUB> reduction catalyst to produce CO with an overpotential ∼1 V lower than a Au catalyst.</P></▼2>

Short-term Effects of Ambient Air Pollution on Emergency Department Visits for Asthma: An Assessment of Effect Modification by Prior Allergic Disease History

Noh, Juhwan,Sohn, Jungwoo,Cho, Jaelim,Cho, Seong-Kyung,Choi, Yoon Jung,Kim, Changsoo,Shin, Dong Chun The Korean Society for Preventive Medicine 2016 Journal of Preventive Medicine and Public Health Vol.49 No.5

Objectives: The goal of this study was to investigate the short-term effect of ambient air pollution on emergency department (ED) visits in Seoul for asthma according to patients' prior history of allergic diseases. Methods: Data on ED visits from 2005 to 2009 were obtained from the Health Insurance Review and Assessment Service. To evaluate the risk of ED visits for asthma related to ambient air pollutants (carbon monoxide [CO], nitrogen dioxide [$NO_2$], ozone [$O_3$], sulfur dioxide [$SO_2$], and particulate matter with an aerodynamic diameter <$10{\mu}m$ [$PM_{10}$]), a generalized additive model with a Poisson distribution was used; a single-lag model and a cumulative-effect model (average concentration over the previous 1-7 days) were also explored. The percent increase and 95% confidence interval (CI) were calculated for each interquartile range (IQR) increment in the concentration of each air pollutant. Subgroup analyses were done by age, gender, the presence of allergic disease, and season. Results: A total of 33 751 asthma attack cases were observed during the study period. The strongest association was a 9.6% increase (95% CI, 6.9% to 12.3%) in the risk of ED visits for asthma per IQR increase in $O_3$ concentration. IQR changes in $NO_2$ and $PM_{10}$ concentrations were also significantly associated with ED visits in the cumulative lag 7 model. Among patients with a prior history of allergic rhinitis or atopic dermatitis, the risk of ED visits for asthma per IQR increase in $PM_{10}$ concentration was higher (3.9%; 95% CI, 1.2% to 6.7%) than in patients with no such history. Conclusions: Ambient air pollutants were positively associated with ED visits for asthma, especially among subjects with a prior history of allergic rhinitis or atopic dermatitis.

농촌 안전관리 실증모델 위한 ICT융합 리빙랩 설계연구

노석봉(Seok-Bong Noh),김하연(Ha-Yeon Kim),노동희(Dong-Hee Noh),최주환(Juhwan Choi) 대한전자공학회 2020 대한전자공학회 학술대회 Vol.2020 No.8

This paper propose the method of ICT Convergence Living Lab for Farming-Safety as Rural Safety Village Model. In this paper, we describe the organizational structure and operation plan of local governments, developers, researchers, and farmers in establishing a living lab for the rural safety management demonstration model. To develop the ICT based Farming-safety model, we describe a system development method for establishing a sensor network based on a Bluetooth gateway and collecting and analyzing agricultural machinery accident data. By establishing the ICT-based rural safety management demonstration model, we expects that it is possible to establish a living lab-based rural safety management demonstration model that can safely manage and prevent agricultural machinery collisions, rollovers, and lost accidents.

Highly Soluble Poly(thienylenevinylene) Derivatives with Charge-Carrier Mobility Exceeding 1 cm²V^–1s^–1

Kim, Juhwan,Lim, Bogyu,Baeg, Kang-Jun,Noh, Yong-Young,Khim, Dongyoon,Jeong, Hyung-Gu,Yun, Jin-Mun,Kim, Dong-Yu American Chemical Society 2011 Chemistry of materials Vol.23 No.21

<P>We report synthesis and characterization of high performance p-type conjugated polymers containing alkyl-substituted thienylenevinylene (PC6TV12T and PC12TV12T) as an active layer for organic thin film transistors (OTFTs). Maximum mobility of annealed PC6TV12T and PC12TV12T films measured in OTFTs showed 0.47 and 1.05 cm<SUP>2</SUP>V<SUP>−1</SUP>s<SUP>−1</SUP>, respectively, in the top-gate/bottom-contact (TG/BC) configuration.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/cmatex/2011/cmatex.2011.23.issue-21/cm2021802/production/images/medium/cm-2011-021802_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/cm2021802'>ACS Electronic Supporting Info</A></P>

A facile approach to improve light extraction for organic light emitting diodes via azobenzene surface relief gratings

Kim, Juhwan,Park, Hong-ju,Na, Seok-In,Noh, Yong-Young,Kim, Dong-Yu Institute of Pure and Applied Physics 2014 Japanese Journal of Applied Physics Vol. No.

<P>We report on synthesis of photo-crosslinkable and photo-bleachable azobenzene based polymer and a facile process for enhancement of light extraction in organic light emitting diodes (OLEDs) using azobenzene surface relief gratings (SRGs). The crosslinked and bleached azobenzene SRGs were achieved using a two-step photo-induced fabrication process. The bleached azobenzene SRGs showed improvement in transmittance in the visible region compared with unbleached azobenzene SRGs. The SRGs were applied to OLEDs based on tris(8-hydroxyquinoline)aluminum(III) (Alq(3)) and poly[2-methoxy-5-(2'-ethyl-hexyloxy)-1,4-phenylene vinylene] (MEH-PPV). As a result, the luminance of both OLEDs was increased by 18% through the use of transparent SRGs. (C) 2014 The Japan Society of Applied Physics</P>

Charge Injection Engineering of Ambipolar Field-Effect Transistors for High-Performance Organic Complementary Circuits

Baeg, Kang-Jun,Kim, Juhwan,Khim, Dongyoon,Caironi, Mario,Kim, Dong-Yu,You, In-Kyu,Quinn, Jordan R.,Facchetti, Antonio,Noh, Yong-Young American Chemical Society 2011 ACS APPLIED MATERIALS & INTERFACES Vol.3 No.8

<P>Ambipolar π-conjugated polymers may provide inexpensive large-area manufacturing of complementary integrated circuits (CICs) without requiring micro-patterning of the individual p- and n-channel semiconductors. However, current-generation ambipolar semiconductor-based CICs suffer from higher static power consumption, low operation frequencies, and degraded noise margins compared to complementary logics based on unipolar p- and n-channel organic field-effect transistors (OFETs). Here, we demonstrate a simple methodology to control charge injection and transport in ambipolar OFETs via engineering of the electrical contacts. Solution-processed caesium (Cs) salts, as electron-injection and hole-blocking layers at the interface between semiconductors and charge injection electrodes, significantly decrease the gold (Au) work function (∼4.1 eV) compared to that of a pristine Au electrode (∼4.7 eV). By controlling the electrode surface chemistry, excellent p-channel (hole mobility ∼0.1–0.6 cm<SUP>2</SUP>/(Vs)) and n-channel (electron mobility ∼0.1–0.3 cm<SUP>2</SUP>/(Vs)) OFET characteristics with the same semiconductor are demonstrated. Most importantly, in these OFETs the counterpart charge carrier currents are highly suppressed for depletion mode operation (<I>I</I><SUB>off</SUB> < 70 nA when <I>I</I><SUB>on</SUB> > 0.1–0.2 mA). Thus, high-performance, truly complementary inverters (high gain >50 and high noise margin >75% of ideal value) and ring oscillators (oscillation frequency ∼12 kHz) based on a solution-processed ambipolar polymer are demonstrated.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2011/aamick.2011.3.issue-8/am200705j/production/images/medium/am-2011-00705j_0009.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/am200705j'>ACS Electronic Supporting Info</A></P>