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인터넷 기반 대화식 저널 쓰기를 통한 중학생의 쓰기 능력 발달 연구1)
소지연 ( So Jiyeon ),차경애 ( Cha Kyung Ae ) 한국외국어대학교 외국어교육연구소 2016 외국어교육연구 Vol.30 No.2
This study explores the impact of e-based interactive dialogue journal writing on Korean middle school students` writing development. The main question addressed in this study was whether there were any changes or progress in students` writing based on their reading journal and dialogue journal. For a qualitative analysis, this study was conducted over a two month period with 2 middle school students. During each lesson, they wrote one reading journal after reading one chapter of a selected storybook and one dialogue journal about the topic that they chose. To set clear evaluation criteria, the students` journals were collected and evaluated by 3 raters based on an analytical writing scale, which was modified from the assessment scale by Tribble (2003). The overall results revealed that there were changes in the students` writing, in both reading journal and dialogue journal. However, both students showed progress more with dialogue journal. They were able to write more clearly and logically, using proper vocabulary in the text with minor grammatical errors. Pedagogical implications and suggestions will be discussed based on the findings of the study.
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근적외선 파장 영역에서 레이저 흡수 분광법을 이용한 화염 내 OH 라디칼 농도 측정에 관한 실험적 연구
소성현(Sunghyun So),유미연(Miyeon Yoo),박지연(Jiyeon Park),김대해(Daehae Kim),박대근(Dae Geun Park),황정호(Jungho Hwang),이창엽(Changyeop Lee) 한국연소학회 2020 한국연소학회지 Vol.25 No.1
As primary carrier of chain branching and propagation reactions, OH (Hydroxyl) radical is one of the most important species in hydrocarbon combustion environment. However, it is no easy to measure the OH radicals concentration in the flame, because it has short duration time, big fluctuation and rapid reaction characteristics. Nevertheless, it is important to measure OH radicals precisely because OH radicals in fames are closely related to combustion efficiency and pollutant emission. To overcome the OH radical concentration measurement in the rapid chemical reaction, TDLAS (Tunable Diode Laser Absorption Spectroscopy) can be a very attractive analysis technique for measuring the concentration of certain species in a gaseous mixture in the flame. In this study, an optical absorption region of OH radical was selected in the near infrared laser (6419 ㎝<SUP>-1</SUP>) to measure OH radical quantitatively in flame. Unfortunately, Most of the light absorption signals of OH radical are interfered by the absorption signals of H₂O. So, the OH radical concentration should be calculated after excluding the contribution of H₂O absorption from united absorption signal of OH and H₂O.
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Achyranthes japonica Nakai-Rice Pilsner 맥주박 열수 추출물의 영양성 및 기능성
오소형(So-Hyeong Oh),정범균(Beom-Gyun Jeong),천지연(Jiyeon Chun) 한국식품영양과학회 2017 한국식품영양과학회지 Vol.46 No.2
본 연구는 지역특산자원인 우슬과 발아벼를 이용하여 Achyranthes japonica Nakai-Rice Pilsner(ARP) 맥주를 제조하고 얻어지는 맥주박의 활용가치를 평가하여 소규모 맥주제조사의 부가가치 생산과 제품개발을 위한 기초자료로 활용하고자 수행되었다. ARP 맥주 제조 시 당화 및 농축공정에서 얻어지는 맥주박 brewer’s spent grain(BSG, 맥아와 미아)와 brewer’s spent material(BSM, 우슬)의 25°C, 60°C, 그리고 100°C 열수 추출액을 제조하고 이들의 영양성 및 기능성을 평가하였다. ARP 맥주박 BSG와 BSM의 열수 추출액의 유용성분 추출량은 추출온도와 시간에 따라 차이를 나타내었으며 γ-aminobutyric acid(GABA), 사포닌, 나이아신 성분은 60°C에서 3시간 이상의 추출에서 함량이 높게 나타났지만, 총폴리페놀 성분과 항산화능[1,1-diphenyl-2-picrylhydrazyl(DPPH) 라디칼 소거능 및 환원력]의 경우 100°C에서 1시간 추출 시 가장 높은 값을 나타내었다. 엽산의 경우 BSG는 100°C에서, BSM은 60°C에서 추출된 시료가 높은 함량을 나타내었다. 전체적으로 영양성과 기능성을 모두 고려해볼 때 60°C에서 3시간의 열수 추출조건이 바람직한 조건으로 보인다. 이 조건하에서 BSG 추출액의 경우 GABA 186.1 μg/100 mL, 나이아신 67.9 μg/100 mL, 엽산 80.9 μg/100 mL, 총폴리페놀 198.8 μg gallic acid equivalent(GAE)/100 mL, DPPH 라디칼 소거능 90.0 μg GAE/100 mL, 환원력 8.4 μg GAE/100 mL, BSM 추출액의 경우 사포닌 300.2 μg diosgenin equivalents/100 mL, 나이아신 1,209.7 μg/100 mL, 엽산 18.0 μg/100 mL, 총폴리페놀 270.4 μg GAE/100 mL, DPPH 라디칼 소거능 1,049.9 μg GAE/100 mL, 환원력 505.5 μg GAE/100 mL를 보이는 것으로 나타났다. BSM의 열수 추출액은 BSG 추출액에 비하여 수용성 비타민의 경우 약 4~18배, 총폴리페놀 함량은 1.4배, 항산화능은 약 11~60배 높게 나타나 영양성 및 기능성 모두 우수한 것으로 나타났다. 본 연구 결과를 볼 때 ARP 맥주박은 영양성 및 기능성 면에서 우수한 자원으로 60°C에서 3시간 열수 추출물을 향후 제품 개발에 활용 가능할 것으로 판단된다. Two byproducts, brewer’s spent grain (BSG; germinated rice and malt) and brewer’s spent material (BSM; Achyranthes japonica Nakai), were collected during the manufacture of pilsner beer using A. japonica Nakai and germinated rice. Water extracts of BSG and BSM were prepared at different temperatures (25°C, 60°C, and 100°C) for 5 h, and their nutritional and functional properties were investigated. γ-Aminobutyric acid (GABA), saponin, and niacin contents were higher in extracts prepared at 60°C for more than 3 h than the other extracts, whereas total polyphenol content, DPPH radical scavenging activity, and reducing power were higher in samples extracted at 100°C for 1 h compared to the other ones. Overall, water extraction at 60°C for 3 h was desirable to effectively collect both nutritional and functional components from BSG and BSM. Under these conditions, BSM extracts showed 4∼18 times high niacin and folate contents, 1.4 times high total phenolic content, and 11∼60 times high antioxidant activities compared to BSG extracts. This study shows that pilsner beer byproducts would be good sources of health beneficial components, especially GABA, saponin, water soluble vitamins, and polyphenolics.
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Ock, Jiyeon,Han, Hyung S,Hong, Su H,Lee, So Y,Han, Young-Min,Kwon, Byoung-Mog,Suk, Kyoungho Wiley (Blackwell Publishing) 2010 British journal of pharmacology Vol.159 No.8
<P>BACKGROUND AND PURPOSE: Obovatol isolated from the medicinal herb Magnolia obovata exhibits a variety of biological activities. Here, the effect of obovatol and its mechanism of action on microglial activation, neuroinflammation and neurodegeneration were investigated. EXPERIMENTAL APPROACH: In microglial BV-2 cells stimulated with lipopolysaccharide (LPS), we measured nitric oxide (NO) and cytokine production, and activation of intracellular signalling pathways by reverse transcription-polymerase chain reaction and Western blots. Cell death was assayed in co-cultures of activated microglia (with bacterial LPS) and neurons and in LPS- induced neuroinflammation in mice in vivo. KEY RESULTS: Obovatol inhibited microglial NO production with an IC50 value of 10 mM. Obovatol also inhibited microglial expression of proinflammatory cytokines and inducible nitric-oxide synthase, which was accompanied by the inhibition of multiple signalling pathways such as nuclear factor kappa B, signal transducers and activators of transcription 1, and mitogen-activated protein kinases. In addition, obovatol protected cultured neurons from microglial toxicity and inhibited neuroinflammation in mice in vivo. One molecular target of obovatol in microglia was peroxiredoxin 2 (Prx2), identified by affinity chromatography and mass spectrometry. Obovatol enhanced the reactive oxygen species (ROS)-scavenging activity of Prx2 in vitro, thereby suppressing proinflammatory signalling pathways of microglia where ROS plays an important role. CONCLUSIONS AND IMPLICATIONS: Obovatol is not only a useful chemical tool that can be used to investigate microglial signalling, but also a promising drug candidate against neuroinflammatory diseases. Furthermore, our results indicate that Prx2 is a novel drug target that can be exploited for the therapeutic modulation of neuroinflammatory signalling.</P>
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