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      • KCI등재

        Multi-objective Optimization of a Hydrogen-Battery Hybrid Storage System for Offshore Wind Farm Using MOPSO

        Tian Tian,Ma Zetao,Cui Qiong,Shu Jie,Tan Lei,Wang Hao 대한전기학회 2023 Journal of Electrical Engineering & Technology Vol.18 No.6

        Recently, offshore wind farms (OWFs) are gaining more and more attention for its high efficiency and yearly energy production capacity. However, the power generated by OWFs has the drawbacks of intermittence and fluctuation, leading to the deterioration of electricity grid stability and wind curtailment. Energy storage is one of the most important solutions to smooth the wind power and capture its surplus. In this paper, we provide a multi-objective optimization approach that combines multi-objective particle swarm optimization and rule-based energy management strategy for an on-gird offshore wind-hydrogen-battery system to simultaneously address the economic (Eco), the qualified rate of smoothing offshore wind power fluctuations (QRS), and the rate of offshore wind power curtailment (ROC). Results revealed that ROC and Eco, QRS and Eco are negatively correlated, but ROC and QRS are positively correlated. The hybrid storage system is more conducive to improve QRS and reduce ROC. Comparing with other three systems, the improvement range for ROC is between 13.6 and 46% when QRS is 100%. In addition, battery storage improves QRS by 2.6%, hydrogen storage deteriorates Eco by 86.8% and improve ROC by 38.5%, the change of ROC and QRS brings by transmission project are close to 100% and 4.4%.

      • KCI등재

        Chemerin/CMKLR1 pathway exacerbates cisplatin-induced spiral ganglion neuron injury

        Tian Jie,Mu Ying,Ma Lili 한국독성학회 2024 Toxicological Research Vol.40 No.1

        This study investigated whether chemerin/chemokine-like receptor 1 (CMKLR1) pathway participate in cisplatin‐induced spiral ganglion neuron (SGN) damage. Middle cochlear turn was collected from C57BL/6 mice and the SGNs were cultured. Cisplatin, 2-(anaphthoyl) ethyltrimethylammonium iodide (α-NETA), or recombinant mouse chemerin was added into the medium for the treatment. Relative mRNA and protein expression was determined by RT-PCR, ELISA and Western blot, respectively. In cultured mouse cochlear SGNs, the treatment of cisplatin enhanced the secretion of chemerin and CMKLR1. Recombinant chemerin promoted but α-NETA inhibited chemerin/CMKLR1 pathway in cisplatin stimulated SGNs. Cisplatin-induced apoptosis and inflammation response in SGNs were enhanced by recombinant chemerin while inhibited by α-NETA. Recombinant chemerin promoted but α-NETA inhibited NF-κB signal in cisplatin stimulated SGNs. In conclusion, chemerin/CMKLR1 pathway regulated apoptosis and inflammation response in cisplatin-induced SGN injury through NF-κB signaling pathway.

      • KCI등재

        Antitumorigenic and antiangiogenic efficacy of apatinib in liver cancer evaluated by multimodality molecular imaging

        Jie Tian,Qian Liang,Lingxin Kong,Yang Du,Xu Zhu 생화학분자생물학회 2019 Experimental and molecular medicine Vol.51 No.-

        Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related mortality worldwide. Sorafenib is the standard first-line treatment for advanced HCC, but its efficacy is limited. Apatinib is a small-molecule tyrosine kinase inhibitor that has shown promising antitumor effects in gastric and non-small cell lung cancers in clinical trials, but there have been only a few studies reporting its anti-HCC effects in vitro and in HCC xenograft models. Hence, our present study systemically investigated and compared the antitumorigenic and antiangiogenic efficacy of apatinib and sorafenib in HCC in vitro and in vivo using multimodality molecular imaging, including bioluminescence imaging (BLI), bioluminescence tomography (BLT), fluorescence molecular imaging (FMI), and computed tomography angiography (CTA). Moreover, the safety and side effects of the two drugs were systemically evaluated. We found that apatinib showed a comparable therapeutic efficacy to sorafenib for the inhibition of HCC. The drug safety evaluation revealed that both of these drugs caused hypertension and mild liver and kidney damage. Sorafenib caused diarrhea, rash, and weight loss in mice, but these effects were not observed in mice treated with apatinib. In conclusion, apatinib has similar antitumorigenic and antiangiogenic efficacy as sorafenib in HCC with less toxicity. These findings may provide preclinical evidence supporting the potential application of apatinib for the treatment of HCC patients.

      • New Issues on Legal Sanction in Korea, China and Japan Position of Criminal Law in Risk Society

        ( Hong Jie Tian ) 아세아여성법학회 2013 아세아여성법학 Vol.16 No.-

        Risk society is not only a cognitive theory at the cultural level, but also features on its reflection significance at the political level and its reconfiguration connotation at the institutional level. Thus, any interpretation or analysis made from any single aspect for the risk society is unavoidably unilateral and single-track. The features of the risk society are increasingly prominent in modem society, which indicates the insufficiencies of the central governance capacity of the State and the failure of rigid governance mode created by laws. Therefore, facing the challenges of the risk society, no matter the adjustments on the governance structure or the society and reforms on the governance mode of the State, are continuously in pursuit of rational limitation of powers of the State, scientific configuration of multi-governance mechanism and firm defending for position of restraint of criminal law, rather than reinforcement of the power of the State and active expansion of function of criminal law.

      • KCI등재

        동시 질산화-탈질(SND) 반응을 적용한 MBR 반응조에서 질소 및 인 제거 특성

        전동걸(Dong Jie Tian),임현숙(Hyun Suk Lim),안찬현(Chan Hyun An),이봉규(Bong Gyu Lee),전항배(Hang Bae Jun),박찬일(Chan Il Park) 大韓環境工學會 2013 대한환경공학회지 Vol.35 No.10

        동시 질산화 탈질은 미세 용존 산소하에 한 반응조내에서 일어난다. 따라서, 본 연구에서는 인 방출을 위해 공기가 공급되는 MBR 전단에 혐기성 존을 만들어주었으며, 높은 DO 농도에서 탈질효율을 향상시켜 주기 위해서는 MBR 내에 배플을 설치하여 무산소 존이 이루어지게 하였다. 그리고 인 제거를 위한 테스트는 MBR 전단의 혐기성 반응조에 알럼 응집제를투입하여 수행하였다. 질소 제거를 위한 SND의 최적 DO 농도 도출은 MBR 내 DO 농도를 2.0, 1.5, 1.0, 0.75 mg/L의 다양한조건에서의 운전을 통해 수행하였다. 심지어 높은 알칼리성 하수라 알럼 응집제를 투입하였을 때 알칼리 용액 첨가 없이도 pH 는 7.0~8.0로 유지되었다. TCODcr와 NH₄+-N의 제거 효율은 모든 DO 농도에서 90% 이상이었다. DO 농도 2.0, 1.5, 1.0, 0.75mg/L에서의 TN 제거효율은 각각 50, 51, 54, 66%이었다. DO 농도 0.75 mg/L 조건에서 알럼을 첨가한 결과 TN 제거효율은 54%로 감소하였다. 혐기성 반응조에 알럼을 투입한 결과 TP 제거효율은 29%에서 95%로 향상되었다. 그리고 알럼 투입 후 분리막모듈의 화학적 세정 주기는 15~20일부터 40~50일으로 늘어났다. Simultaneous nitrification and denitrification (SND) occurs concurrently in the same reactor under micro dissolved oxygen (DO) conditions. Anaerobic zone was applied for phosphorus release prior to an aerated membrane bio-reactor (MBR), and anoxic zone was installed by placing a baffle in the MBR for enhancing denitrification even in high DO concentration in the MBR. Phosphorus removal was tested by alum coagulation in the anaerobic reactor preceding to MBR. DO concentration were 2.0,1.5, 1.0, 0.75 mg/L in the MBR at different operating stages for finding optimum DO concentration in MBR for nitrogen removal by SND. pH was maintained at 7.0~8.0 without addition of alkaline solution even with alum addition due to high alkalinity in the raw sewage. Both TCODcr and NH₄+-N removal efficiency were over 90% at all DO concentration. TN removal efficiencies were 50, 51, 54, 66% at DO concentration of 2.0, 1.5, 1.0, 0.75 mg/L, respectively. At DO concentration of 0.75 mg/L with addition of alum, TN removal efficiency decreased to 54%. TP removal efficiency increased from 29% to 95% by adding alum to anaerobic reactor. The period of chemical backwashing of the membrane module increased from 15~20 days to 40~50 days after addition of alum.

      • KCI등재

        基于朝鲜半岛地缘价值的中国外交政策应对

        田?杰(Tian, Hong-jie) 한국동북아학회 2019 한국동북아논총 Vol.24 No.4

        한반도는 동북아 지역에서 매우 중요한 지정학적 가치를 가지고 있는데 이는 시기에 따라 달리 나타난다. 20세기 초반부터 지금까지 한반도를 둘러싸고 일련의 격렬한 이익충돌, 이를테면 한국전쟁을 비롯한 열전과 냉전이 벌어졌다. 전반적으로 한반도의 지정학적 가치 변천은 긍정적인 것과 부정적인 것의 두 가지 방향으로 진행되고 있다. 한반도를 둘러싼 강대국 정치의 각축이 여전히 치열하고, "북핵 위기"가 동북아 지역의 평화와 안보를 심각하게 위협하고 있는 한편, 한반도의 지정학적 주제는 안보와 평화, 협력과 발전, 화해와 통일의 추세로 나아가고 있다. 중국과 한반도의 지정학적 이해관계가 복잡하게 얽혀 있는 상황에서 중국은 시대 변화 및 한반도 지정학적 가치의 전환에 따라 그에 상응한 시기적절한 정책 조율이 필요하다. For northeast Asia, the Korean peninsula highlights its geopolitical significance periodically, which has a very important geostrategic value. Especially since the beginning of the 20th century, it has become the focus of the contention among the neighboring powers. Fierce conflicts of interests exist around the Korean peninsula, including hot wars such as the Korean wars and cold wars. The geopolitical value of the Korean peninsula develops towards both positive and negative directions. The current political competition among great powers around the Korean peninsula is still very fierce, and the "Korean nuclear crisis" seriously threatens the peace and security process in northeast Asia. However, the geopolitical value of the Korean peninsula is undergoing a profound transformation. In particular, security and peace, cooperation and development, and reconciliation and reunification are becoming the general trend. The geopolitical interests of China and the Korean peninsula are interwoven, so it is imperative for China to make timely policy changes along with the corresponding shift of geopolitical value in the new trend.

      • KCI등재

        혐기성 하수처리공정에서 UASB HRT에 따른 유기물질 제거특성

        전동걸 ( Dong Jie Tian ),임현숙 ( Hyun Suk Lim ),이봉규 ( Bong Gyu Lee ),임병서 ( Byung Seo Lim ),전항배 ( Hang Bae Jun ) 한국수처리학회 2014 한국수처리학회지 Vol.22 No.3

        The effect of UASB HRT (up-flow anaerobic sludge blanket hydraulic retention time) on the removal of organic matter was investigated in a UASB-ABF (aerated bio-filter) anaerobic sewage treatment system at 3 different HRTs (72, 25 and 3hr). 30% of the influent TCOD was SCOD, and the last 70% was SSCOD of the raw sewage flowing into the primary sedimentation basin. 82% of the influent TCOD was removed in 72 hr UASB(caseⅠ), and 78mL of methane gas was produced per removed grams of COD. Similar TCOD removal occurred in caseⅡ, the UASB HRT of 25hr, while 71% of the influent TCOD was removed in caseⅢ, with a UASB HRT of 3hr. Methane gas did not produced enough to be measured in both caseⅡ and caseⅢ. Unlike TCOD removal, SS and turbidity removal occurred effectively in caseⅢ. About 40% of influent SCOD was removed by UASB at caseⅠ and caseⅡ, however, little SCOD was removed in caseⅢ. Almost 70% of influent TCOD was wasted as the raw sludge from UASB in caseⅢ.

      • PKM2 Regulates Hepatocellular Carcinoma Cell Epithelial-mesenchymal Transition and Migration upon EGFR Activation

        Fan, Fang-Tian,Shen, Cun-Si,Tao, Li,Tian, Chao,Liu, Zhao-Guo,Zhu, Zhi-Jie,Liu, Yu-Ping,Pei, Chang-Song,Wu, Hong-Yan,Zhang, Lei,Wang, Ai-Yun,Zheng, Shi-Zhong,Huang, Shi-Le,Lu, Yin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.5

        Pyruvate kinase isozyme type M2 (PKM2) was first found in hepatocellular carcinoma (HCC), and its expression has been thought to correlate with prognosis. A large number of studies have demonstrated that epithelial-mesenchymal transition (EMT) is a crucial event in hepatocellular carcinoma (HCC) and associated metastasis, resulting in enhanced malignancy of HCC. However, the roles of PKM2 in HCC EMT and metastasis remain largely unknown. The present study aimed to determine the effects of PKM2 in EGF-induced HCC EMT and elucidate the molecular mechanisms in vitro. Our results showed that EGF promoted EMT in HCC cell lines as evidenced by altered morphology, expression of EMT-associated markers, and enhanced invasion capacity. Furthermore, the present study also revealed that nuclear translocation of PKM2, which is regulated by the ERK pathway, regulated ${\beta}$-catenin-TCF/LEF-1 transcriptional activity and associated EMT in HCC cell lines. These discoveries provide evidence of novel roles of PKM2 in the progression of HCC and potential therapeutic target for advanced cases.

      • 알루미늄전극과 산화철 여과를 이용한 하수 방류수 내 인의 제거

        전동걸 ( Dong Jie Tian ),임현숙 ( Hyun Sook Lim ),변병수 ( Byeong Su Byun ),전항배 ( Hang Bae Jun ) 충북대학교 건설기술연구소 2014 建設技術論文集 Vol.33 No.1

        인은 하천, 호소의 부영영화의 주요한 영양소이다. 2013년부터 하수 방류수 내 인은 2.0mg/L에서 0.2mg/L로 강화된다. 따라서, 본 연구에서는 알루미늄전극과 산화철 여과지로 하수 방류수 내 인 제거 실험을 수행하였다. 최적인자 도출을 위한 다양한 회분식 실험은 인공폐수를 사용하여 수행하였다. 알루이늄전극 전기분해에 대한 최적 전압과 HRT는 유입 인 농도 0.5~2.0mg/L에서 각각 20V, 120sec이었다. 따라서, 이때의 인 제거효율은 97.3%이었다. 알루미늄전극 전기분해와 산화철 여과에 의한 실제 하수 방류수 연속 운전에서는 인 제거효율이 각각 82.9%, 87.3%이었다. 결과적으로 알루미늄전극 전기분해와 산화철 여과지에서 98%의 안정적인 인 제거로 하수 방류가 가능하였다. 이러한 조합인 제거 공정은 0.2mg/L의 배출기준을 만족하엿다. Phosphorus is an important nutrient causing the eutrophication which decreases the valuse of rivers, lakes and estuaries. From 2013, the sewage effluent standard of the phosphorus is planning to strengthen from 2.0mg/L to 0.2mg/L. In this paper, the alurninium electrode and oxidized iron filtration were tested for the removal of phosphorus in sewage effluent. Several batch tests were also performed using the artificial wastewater to find the optimum operating conditions. Optimal voltge and HRT(hydraulic retention time)for aluminium electroysis were 20V and 120sec at influent phosphorus of 0.6~2.0mg/L, respectively. In these conditions, the phosphorus removal efficiency was 97.3%. On the continuous operation of the aluminium electrolysis and oxidized iron filtration with actual sewage effluent the phosphorus removal efficiency were 82.9% and 87.3%, respectively. Finally, stable 98% phosphorus removal was possible from the effluent of sewage with both aluminium electrode and oxidized iron filtration. These combined phosphorus removal processes are suitable to meet the effluent standards, 0.2mg/L.

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