http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Chen Ziming,Li Mengyuan,Chen Peilin,Tai Andrew,Li Jiayue,Bassonga Euphemie Landao,Gao Junjie,Liu Delin,Wood David,Kennedy Brendan F.,Zheng Qiujian,Zheng Ming H. 생화학분자생물학회 2024 Experimental and molecular medicine Vol.56 No.-
Tendinopathy is one of the most common musculoskeletal diseases, and mechanical overload is considered its primary cause. However, the underlying mechanism through which mechanical overload induces tendinopathy has not been determined. In this study, we identified for the first time that tendon cells can release extracellular mitochondria (ExtraMito) particles, a subtype of medium extracellular particles (mEPs), into the environment through a process regulated by mechanical loading. RNA sequencing systematically revealed that oxygen-related reactions, extracellular particles, and inflammation were present in diseased human tendons, suggesting that these factors play a role in the pathogenesis of tendinopathy. We simulated the disease condition by imposing a 9% strain overload on three-dimensional mouse tendon constructs in our cyclic uniaxial stretching bioreactor. The three-dimensional mouse tendon constructs under normal loading with 6% strain exhibited an extended mitochondrial network, as observed through live-cell confocal laser scanning microscopy. In contrast, mechanical overload led to a fragmented mitochondrial network. Our microscopic and immunoblot results demonstrated that mechanical loading induced tendon cells to release ExtraMito particles. Furthermore, we showed that mEPs released from tendon cells overloaded with a 9% strain (mEP9%) induced macrophage chemotaxis and increased the production of proinflammatory cytokines, including IL-6, CXCL1, and IL-18, from macrophages compared to mEP0%, mEP3%, and mEP6%. Partial depletion of the ExtraMito particles from mEP9% by magnetic-activated cell sorting significantly reduced macrophage chemotaxis. N-acetyl-L-cysteine treatment preserved the mitochondrial network in overloaded tendon cells, diminishing overload-induced macrophage chemotaxis toward mEP9%. These findings revealed a novel mechanism of tendinopathy; in an overloaded environment, ExtraMito particles convey mechanical response signals from tendon cells to the immune microenvironment, culminating in tendinopathy.
Chen, Pengqi,Xu, Xian,Wei, Bangzheng,Chen, Jiayu,Qin, Yongqiang,Cheng, Jigui Korean Nuclear Society 2021 Nuclear Engineering and Technology Vol.53 No.5
Oxide dispersion strengthening (ODS) tungsten alloys are highly desirable in irradiation applications. However, how to improve the properties of ODS-tungsten alloys efficiently has been worth studying for a long time. Here we report a nanostructuring approach that achieves W-La<sub>2</sub>O<sub>3</sub> alloy with a high level of flexural strength and Vickers hardness at room temperature, which have the maximum value of 581 MPa and 703 Hv, respectively. This method named solution combustion synthesis (SCS) can generate 30 nm coating structures W-La<sub>2</sub>O<sub>3</sub> composite powders by using Keggin-type structural polyoxometalates as raw materials in a fast and low-cost process. The composite powder can be fabricated to W-La<sub>2</sub>O<sub>3</sub> alloy with an optimal microstructure of submicrometric W grains coexisting with nanometric oxide particles in the grain interior, and a stability interface structure of grain boundaries (GBs) by forming transition zones. The method can be used to prepare new ODS alloys with excellent properties in the future.
Structure-Mechanical Property Relationships of 3D-Printed Porous Polydimethylsiloxane
Jiayu Zhao,Rebekah Woo,Grace Chen,Jinhye Bae 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.2
We studied the structure-mechanical property relationship to demonstrate the highly tunable mechanical properties of printed porous PDMS via direct ink writing. To enable 3D printing, we develop a porous PDMS ink consisting of a PDMS precursor, silicone oil, dibutyl phthalate (DBP), and fumed silica nanoparticles by tuning the rheological behaviors. The rheological impact of each component was characterized by viscosity, storage modulus and loss modulus measurements. The porous structures in PDMS are subsequently generated by the removal of DBP in the cured PDMS matrix and characterized by scanning electron microscopy. Mechanical characterization exhibits that the printed sample using the porous PDMS precursor has enhanced stiffness, strength, toughness, and ductility compared to the nonporous PDMS sample. Notably, a broad range of mechanical properties is achieved by varying structural parameters (i.e. , infill densities and printing patterns) for 3D printing of a single porous PDMS material system, which provides insight for designing adaptive soft robots and actuators that can integrate different mechanical properties into a single device by simply changing the structural parameters.
Chen, Mingyuan,Hu, Jiayu,유승철 한국인터넷방송통신학회 2024 International journal of advanced smart convergenc Vol.13 No.1
In digital marketing, the strategic use of emojis in social media advertising, particularly on the Xiaohongshu app, significantly influences consumer acceptance and purchase behavior. This study examines the impact of emoji-laden advertisements and the role of brand metaphorical warmth on consumer perceptions. Employing a tailored questionnaire, the research explores how emojis affect brand advertisement reception, filling a gap in empirical research on emoji advertising effectiveness. Findings indicate that emojis, when used judiciously, enhance consumer acceptance and contribute to a positive brand perception. However, excessive use may undermine trust. Brand metaphorical warmth emerges as a crucial factor, suggesting that emojis can effectively convey warmth, fostering a deeper emotional connection with consumers. These insights offer practical implications for refining social media marketing strategies, advocating for a balanced approach to emoji usage in advertisements to optimize engagement and influence consumer behavior.
Corporate Social Responsibility and Unsecured Debt: Evidence from China
Xia CHEN,Zhe MA,Jiayu SHI,Bingyan TU,Songtao XU 한국유통과학회 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.11
This study aims to investigate whether Corporate Social Responsibility (CSR) performance can help companies gain more bank unsecured loans. Additionally, this study analyzes the moderating effect of firm size and industry characteristics. Data was collected through the case of companies listed on the Shanghai Stock Exchange or the Shenzhen Stock Exchange in China between 2009 and 2018 with 5373 firmyear observations. The results of multivariable regression analysis show that good CSR performance exhibits a strong positive impact on unsecured debt, including short-term, long-term, and total unsecured debt, which indicates that corporate with good CSR performance can borrow more unsecured debt. further research shows that this effect is more pronounced for small enterprises and firms operating in heavy-polluting industries. Additionally, research on the impact mechanism finds that good CSR performance can help mitigate information asymmetry between borrower and lender, reduce moral hazard of borrower, and obtain support from key stakeholders, and therefore reduces the risk of default. The findings of this study suggest that firms with good CSR performance exhibit a preference for unsecured debt, but decline to provide collateral for debt. Overall, we emphasize and illustrate the important role of corporate CSR in bank credit financing.
Hu, Jiayu,Chen, Mingyuan,유승철 한국인터넷방송통신학회 2024 International journal of advanced smart convergenc Vol.13 No.1
This study explores an innovative advertising technique on Bilibili, where product links are embedded as bullet comments visible only to mobile app users. The research involved 140 participants, divided equally between followers and non-followers of a popular influencer, ‘Gourmet WanggangR.’ These groups were further split, with half viewing a video containing the product link on the app and the other half via PC. The study revealed that influencer attachment significantly increased viewer immersion (transportation) and positively influenced attitudes towards the content, which in turn elevated purchase intentions. Importantly, the influencer’s followers showed a stronger attachment and more favorable attitudes towards the content, alongside a heightened likelihood to purchase the advertised product. The presence of the product link further accentuated these effects among the influencer’s followers. Conversely, in the absence of the link, the correlation between influencer attachment and content attitude was less pronounced. These findings highlight the effectiveness of embedding product links in video content as a marketing strategy, particularly when targeting an influencer’s followers through mobile platforms.
A Novel Gate Driver for Suppressing Overcurrent and Overvoltage of SiC MOSFET
Jiangui Chen,Yan Li,Mei Liang,R.Kennel,Jiayu Liu,Haobo Guo 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5
SiC MOSFET has faster switching speed, lower RDS(on), and higher breakdown voltage when compared with Si MOSFET. Therefore, SiC MOSFET can work at work at higher frequencies, even Mhz. However, the overvoltage and overcurrent (OVOC) of SiC MOSFET become more serious with the increase of frequency due to the low damping and the parasitic parameters in the actual circuit. The causes of overcurrent and overvoltage of SiC MOSFET are analyzed in this paper, and a gate driver with the variable gate resistance and the variable driving voltage and is proposed to suppress OVOC of SiC MOSFET. This paper analyzes the working mode of the proposed gate driver (PGD).The PGD can effectively suppress the OVOC of SiC MOSFET. Finally, the effectiveness of the PGD is verified based on a doublepulse test platform.
Robust Organic Memristors for Neuromorphic Computing
Wen Li,Jiayu Li,Ye Chen,Yangzhou Qian,Jia Zhou,Mingdong Yi 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.2
Materials (IAM), Nanjing University of Posts and Telecommunications Neuromorphic computing is considered to be a new computer architecture that can break through the von Neumann bottleneck in the era of big data and artificial intelligence because of its efficient information processing capabilities. Over the last decade, organic memristors have been under the spotlight of the neuromorphic research community not only for their capability of emulating functionalities of biological synapses but also for the merits of using organic materials including low cost, solution processability, and flexibility. However, delivering stable organic memristors under ambient condition remains a significant challenge. Recently we developed robust organic memristors through the use of environmentally stable materials and the fabrication of nanostructured film. The unencapsulated devices exhibit high operational stability under harsh conditions such as high and low temperature, high humidity, etc. These results could pave the way for organic memristors in progressing their practicality.
The Vis-NIR multicolor emitting phosphor Ba4Gd3Na3(PO4)6F2: Eu2+, Pr3+ for LED towards plant growth
Ziwei Zhou,Niumiao Zhang,Jiayu Chen,Xianju Zhou,Maxim S. Molokeev,Chongfeng Guo 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.65 No.-
Photosynthesis process is the basic for plant growth, which needs energy from the light. The pigments of chlorophyll a, b and bacteriochlorophyll are responsible for the absorption of light, in which blue, red and near-infrared (NIR) light directly or indirectly promote the plant growth and enhancement of nurtiments. It is important for plant to support absorbable light, and phosphhor-converted light emitting diodes (pc-LEDs) are low-cost, energy-saving and enviromental friendly devices for plant growth. To develop a phosphor with emission covering the blue, red and NIR, a series of phosphors Ba4Gd3Na3(PO4)6F2: Eu2+, Pr3+ with blue, red and NIR multi-emitting were prepared. Their emissions not only match well with the absorption spectra of pigments in the plant, but also could be excited by near ultraviolet (n-UV) LED chip. The crystal structure of host Ba4Gd3Na3(PO4)6F2 was refined from the XRD data and three different crystallographic sites occupied by Eu2+ were determined through low temperature photoluminescence spectra. The energy transfer from Eu2+ to Pr3+ ions was also discussed in detail. Results indicated that the multi-emitting Ba4Gd3Na3(PO4)6F2: Eu2+, Pr3+ can serve as a phosphor candidate for plant growth LEDs.