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Son, Jongha,Kwon, Yongbeom,Kim, Janghyuk,Kim, Jihyun The Electrochemical Society 2018 ECS journal of solid state science and technology Vol.7 No.8
<P>Monoclinic beta-Ga2O3 with an ultra-wide energy bandgap of similar to 4.9 eV has facile cleavage planes because of the high anisotropy in the lattice structure. An exfoliated nanolayer flake of beta-Ga2O3 can be used as an active channel layer in nanoelectronics. However, the mechanical exfoliation method used poses a fundamental issue in that the separated individual layer has a random thickness, which makes it challenging to obtain reproducible device performance. In our study, we demonstrated a photo-enhanced chemical etching technique to control the thickness of exfoliated beta-Ga2O3 nanolayers, enabling us to adjust the threshold voltage of field-effect transistors (FETs) based on these nanolayers. Thickness-dependent device characteristics (threshold voltage, subthreshold swing, on/off ratio, and field-effect mobility) of the back-gated FETs were investigated as a function of the active channel layer (beta-Ga2O3) thickness achieved by the photo-enhanced H3PO4 etching. Our study paves the way for the implementation of exfoliated beta-Ga2O3 nanolayers in nanoelectronics. (C) 2018 The Electrochemical Society.</P>
Jaeho Park,Hong Xi,Jiyun Han,Jeongmin Lee,Yongsung Kim,Jun-mi Lee,Janghyuk Son,Joungjwa Ahn,Taewon Jang,Jisoo Choi,Jongsun Park 중소기업융합학회 2020 융합정보논문지 Vol.10 No.3
최근에 한국 고유종인 미선나무 (Abeliophyllum distichum Nakai; Oleaceae) 품종 옥황1호의 유전체가 성공적으로 해독되었다. Acteoside는 다양한 활성을 가지는 물질이며, 여러개의 생화학합성과정이 제시되어왔고, 이들을 통합 검토하여 정 확한 생화학합성과정을 완성하였다. 유전체 데이터로부터 2차대사산물을 예측할 수 있는 MetaPre-AITM와 정확한 acteoside 생화학합성과정, InfoBoss Pathway Database를 활용하여, acteoside에 관여하는 모든 효소의 유전자를 옥황1호 유전체로부 터 성공적으로 확인하였다. 이는 옥황1호는 acteoside 물질을 생산할 수 있는 가능성이 있음을 의미한다. 이에 고성능액체크로 마토그래피를 사용하여 옥황1호의 캘러스 세포를 분석하여 acteoside과 이의 유도체인 isoacteoside를 확인하였다. 본 연구는 MetaPre-AITM은 유전체로부터 2차대사산물을 성공적으로 예측하였다. 이 방법은 화학물질보다 안정적인 DNA를 분석하여 2 차 대사산물을 예측하는 효율적인 방법이 될 것이다. Whole genome sequence of Abeliophyllum distichum Nakai (Oleaceae) cultivar Ok Hwang 1 Ho, which is Korean endemic species, was recently sequenced to understand its characteristics. Acteoside is one of major useful compounds presenting various activities, and its several proposed biochemical pathways were reviewed and integrated to make precise biochemical pathway. Utilizing MetaPre-AITM which was developed for predicting secondary metabolites based on whole genome with the precise biochemical pathway of acteoside and the InfoBoss Pathway Database, we successfully rescued all enzymes involved in this pathway from the genome sequences, presenting that A. distichum cultivar Ok Hwang 1 Ho may produce acteoside. High-performance liquid chromatography result displayed that callus of A. distichum cultivar Ok Hwang 1 Ho contained acteoside as well as isoacteoside which may be derived from acteoside. Taken together, we successfully showed that MetaPre-AITM can predict secondary metabolite from plant whole genomes. In addition, this method will be efficient to predict secondary metabolites of many plant species because DNA can be analyzed more stability than chemical compounds.