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Jang, Sang Hee,BOK, SONG HAE,Cho, Kyung Hyun,Choi, Myung Sook,Park, Yong Bok,Shin, Yong Won 생화학분자생물학회 1998 BMB Reports Vol.35 No.2
We previously reported that cholesterol ester transfer protein (CETP) inhibitory peptides (designated P_(28) and P_(10) have anti-atherogenic effects in hypercholesterolemic rabbits (Biochim. Biophys. Acta (1998) 1391, 133-144). To further investigate those effects, we studied rabbit plasma that was collected after 30 h of a P_(28) or P_(10) injection. We found that there is a strong correlation between the in vivo CETP inhibition effects and alterations of lipoprotein particle size distribution in rabbit plasma, as determined on an agarose gel electrophoresis and gel filtration column chromatography. In vivo effects of the peptide were observed again in C57BL/6 mice that expressed simian CETP. The P_(28) or P_(10) peptide (7 ㎍/g of body weight) that was dissolved in saline was injected subcutaneously into the mice. The P_(28) injection caused the partial inhibition of plasma CETP activity up to 50%, decreasing the total plasma cholesterol concentration by 30%, and increasing the ratio of HDL/total-cholesterol concentration by 150% in the CETP-transgenic (tg) mice. The CETP inhibition by the P_(28) or P_(10) made alterations that modulated the size re-distribution of the lipoproteins in the blood stream. Particle size of the very low (VLDL) and low density lipoproteins (LDL) from the peptide-injected group was highly decreased compared to the saline-injected group (determined on the gel filtration column chromatography). In contrast, The HDL particle size of the P_(28)-injected group increased compared to the control group (saline-injected). The expression level of the CETP mRNA of the P_(28)-injected CETP-tg mouse appeared lower than the saline-injected CETP-tg mouse. These results suggest that the injection of the CETP inhibitory peptide could affect the CETP expression level in the liver by influencing lipoprotein metabolism.
장금성(Jang, Keum Seong),김복남(Kim, Bok Nam),정석희(Jeong, Seok Hee),김윤민(Kim, Yun Min),김정숙(Kim, Jung Sook) 한국간호행정학회 2016 간호행정학회지 Vol.22 No.5
Purpose: This study was conducted to develop a nursing leadership program outcome evaluation system, required for accreditation of nursing education. Methods: A methodological design was used. To ensure the theoretical validity of the evaluation system, learning objectives for nursing education programs and job descriptions for nurses in Korea were verified by analyzing the relationships in the five attributes of the nursing leadership concept. The nursing leadership program outcome evaluation system was developed based on the Kim & Park’s developmental model (2008). Results: The nursing leadership program outcome evaluation system was established, including implementation level, education curriculum, level of performance, evaluation method, rubrics, and Close-the-Loop. Conclusion: The developed evaluation system can be actively used in nursing education, and contribute to enhancing the leadership competencies of nursing students and graduate nurses.
부산타워<TEX>${\bigcirc}{\bigcirc}$</TEX>소방시설등의 성능위주설계 사례
장원복(Jang, Won-Bok),황금숙(Hwang, Keum-Sook),신현승(Shin, Hyun-Seung) 한국화재소방학회 2011 한국화재소방학회 학술대회 논문집 Vol.2011 No.추계
소방방재청 고시 제2011-68호에 의한 소방시설등의 성능위주 설계 방법 및 기준에 의한 부산<TEX>${\bigcirc}{\bigcirc}$</TEX>타워의 성능설계심의 절차및 과정 등의 사례 소개를 목적으로 한다.
중학생의 라면소비 실태조사 : 강원도 지역을 중심으로 Kangwon do Area
김복남,장명숙,현영희 한국조리과학회 1989 한국식품조리과학회지 Vol.5 No.2
강원도지역에 거주하는 만 13∼15세의 중학교 학생 866명을 대상으로 라면소비실태와 품질인자에 대하여 조사한 결과는 다음과 같았다. 1) 총 866명중 67%가 라면을 1주에 1회이상 섭취하고 있었으며 이들 대부분은 가정에서 저녁식사 또는 간식의 형태로 라면을 이용하고 있었다. 2) 라면을 먹는 주된 이유는 편의성과 맛때문인 것으로 나타났으며 라면을 선택할 때는 선전이나 광고에 의하여 이루어지고 있었다. 3) 라면을 먹을때 가장 중요시하는 인자는 국물의 맛이었으며 대체로 보통정도 굵기의 면발을 선호하고 있었다. 4) 면발의 조직감은 쫄깃쫄깃하고 꼬들꼬들한 것을 좋아했으며 흐물거리고 풀어진 면발은 싫어했다. 국물의 맛은 얼큰한 맛을 가장 좋아했으며 그다음이 구수한 맛으로 나타났고 느끼한 맛과 짠맛은 싫어하는 것으로 나타났다. 5) 라면선택방법의 문항을 제외한 모든 문항에서 성별에 따라 유의적인 상관관계가 있었다. Consumption pattern of Ramyon (fried instant noodle) by middle school students at age of 13∼15 years in Kangwon-do area was surveyed by questionaire. About 67% among 866 students consumed Ramyon more than once per week. On the whole, common Ramyon was frequently consumed as a kind of substitues for supper sand between meals at home because of its convenience. The advertisement had strong effect on the selection of ramyon. Consumers considered that taste of soup is important quality factor of Ramyon In terms of the texture of cooked noodle, the most desirable was chewy and hard texture. The most undesirable was swollen and mushy texture. The most desriable and undesirable taste of soup was respectively spicy and greasy taste. At present, no significant difference in consumption pattern betsween sex were observed in most cases.
이장훈(Jang Hoon Lee),김경숙(Kyoung Sook Kim),안종복(Jong Bok Ahn) 한국언어치료학회 2015 言語治療硏究 Vol.24 No.4
Purpose: The simple results of preceding studies suggesting adult people with left hemisphere damage(hereinafter, people with LHD) and people with right hemisphere damage(hereinafter, people with RHD) have deficient simile comprehension requires further systematic studies intended to determine whether there are any statistically significant differences between the two groups if such the deficiency exists. In this context, as a part of systematic studies, the present study was intended to clarify simile comprehension in adults with brain damage. Methods: The subjects of this study included people with LHD, people with RHD and normal adults (ten subjects each). All subjects completed a questionnaire composed of 10 questions about direct simile and 10 questions about indirect simile using illustrated figures. Results: First, when simile comprehension in the three groups were examined closely according to the type of simile, the score of comprehension was the highest in normal group, followed by people with LHD and then people with RHD. A two-way analysis of variance showed a statistically significant difference in groups only. Second, when erroneous responses of simile comprehension in the three groups according to the type of simile were studied, no response was seen in people with LHD, and the frequency of choosing the secondary meaning was relatively higher in people with RHD. In addition, a two-way analysis of variance indicated a statistically significant difference in groups only. Conclusions: Taken together, as a figurative expression, the comprehension of simile and it's the form of erroneous response depend on the damaged hemisphere.
일부 직장근로자들의 건강증진생활양식에 따른 치과의료기관 선택 요인
송귀숙 ( Kwui Sook Song ),장선희 ( Sun Hee Jang ),송복녀 ( Bok Nyeo Song ) 한국치위생학회(구 한국치위생교육학회) 2012 한국치위생학회지 Vol.12 No.1
Objectives : The purpose of this study was to examine the influential factors for the choice of dental institutions among adult office workers who were one of major medical consumer groups, the relationship between their health promotion lifestyle and their choice of dental institutions, ways of boosting the efficiency of hospital management and differences in differentiation strategies among dental institutions. Methods : The subjects in this study were 160 office workers who were aged 20 and over and worked in Seoul, North Jeolla Province and South Jeolla Province. They were selected by convenience sampling, and a survey was conducted from February 1 to July 20, 2011. The answer sheets from 149 respondents were analyzed by the statistical package SPSS WIN 12.0 except for 11 incomplete ones. Results : As for the selection factors of dental institutions by general characteristics, they attached a statistically and significantly different importance to convenience according to gender(p<0.05), to reliability, facilities and cleanness according to age(p<0.05), to reliability and convenience according to academic credential(p<0.05) and to facilities and cleanness according to academic credential(p<0.01). Concerning the links between the form of using dental institutions and the selection factors of dental institutions, they gave a statistically and significantly different weight to reliability according to that(p<0.05). Convenience(p<0.001) was the primary selection factor of dental institutions among those who scored higher in health promotion lifestyle. Conclusions : Given the above-mentioned findings, it seemed that the regular implementation of oral health plans geared toward workers and the development of educational programs are required to promote the oral health of workers. But this study examined the workers in several regions only, and the findings might not be generalizable.(J Korean Soc Dent Hygiene 2011;12(1):179-187)