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Jeong, Sujin,Cho, Seokwon,Lee, Ho Won,Kim, Young Kwan,Yoon, Seung Soo American Scientific Publishers 2017 Journal of Nanoscience and Nanotechnology Vol.17 No.8
<P>Three triphenylsilane-fluorene hybrids as host materials have been synthesized and characterized for phosphorescent organic light emitting diodes (OLEDs). Triphenylsilane and fluorene moieties are introduced to increase thermal stability and triplet energy. Two kinds of devices-green and blue phosphorescent OLEDs-were fabricated to investigate electroluminescent properties of triphenylsilane-fluorene hybrids as host materials. Devices using these materials as phosphorescent hosts showed efficient green as well as blue electroluminescence with the maximum external quantum efficiencies of 9.01 and 10.7%, respectively.</P>
Identification of RNA Aptamer Specific to Mutant KRAS Protein
Jeong, Sujin,Han, Seung Ryul,Lee, Young Ju,Kim, Ju Hyun,Lee, Seong-Wook Mary Ann Liebert 2010 Oligonucleotides Vol.20 No.3
<P>Mutations in the KRAS gene are required for early occurrence and maintenance of tumorigenesis and are the most frequently found in many types of human malignant diseases. Therefore, approaches targeting RAS function have been proposed for cancer therapy. However, no selective and specific inhibitors of KRAS have yet been developed as anticancer agents. In this study, by employing counter-systematic evolution of ligands by exponential enrichment technique, we identified and characterized an RNA aptamer that specifically bound to mutant KRAS protein with a point mutation in codon 12 of the KRAS gene. Real-time polymerase chain reaction analysis, surface plasmon resonance measurements, and competitive precipitation experiments showed that the selected aptamer contained activities of specific and high-affinity binding to the mutant KRAS (K(D) approximately 4.04 nM) but much less binding to the wild type (K(D) approximately 227 nM). This RNA aptamer could be useful as a ligand for specific therapeutics and diagnostics against mutant KRAS-mediated cancers.</P>
Jeong, Sujin,Kim, Changmin,Lee, Ho Won,Kim, Young Kwan,Yoon, Seung Soo American Scientific Publishers 2018 Science of advanced materials Vol.10 No.5
<P>We designed and synthesized three blue EL materials based on 6,11-diphenyl-13H-indeno[1,2-b]anthracene via Suzuki coupling. To investigate their EL properties, we fabricated devices with following the structure: indium-tin-oxide (ITO, 180 nm)/4,4',4 ''-tris[2-naphthyl(phenyl)amino (2-TNATA, 60 nm)/4,4'-bis(N-(1-naphthyl)-N-phenylamino)biphenyl (NPB, 20 nm)/Blue emitting materials (30 nm)/Bathophenanthroline (Bphen, 30 nm)/lithium quinolate (Liq, 2 nm)/AI (100 nm). The device using 1,3-bis(13,13-dimethyl-6,11-diphenyl-13H-indeno[2,1-b]anthracen-2-yl)benzene as blue emitting material showed highly efficient blue emission the luminous, power, and external quantum efficiencies of 2.97 cd/A, 1.27 Im/W, and 2.23% at 20 mA/cm(2), respectively. The CIE coordinates of this device were (0.15, 0.22) at 6.0 V. This study suggests that the intrinsic luminescent capability and the degree of self-aggregation of the emitters contribute greatly to electroluminescent properties of devices.</P>
Deposition and XPS Study of Pb, Zr, and Ti Films
Sujin Choi, Juyun Park, Eunkang Jeong, Beob jun Kim, Seo yoon Son, Jeong min Lee, Jin seong Lee, Hee jin Jo, Jihun Park, Yong-Cheol Kang 조선대학교 기초과학연구원 2014 조선자연과학논문집 Vol.7 No.3
Lead zirconate titanate (PZT) is significant material in electrical and optical devices for their ferroelectric, piezoelectric and dielectric properties. In this research, PZT films were fabricated by reactive RF co-sputtering method using Pb, Zr, and Ti targets. From XPS study, lead, zirconium, and titanium are successfully deposited on Si(100) substrate. Thickness of PZT films was measured with a surface profiler and the thickness was decreased as the oxygen gas ratio increased in the sputter gas.