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Li, Hong-Sheng,Chen, Jin-Hu,Zhang, Wei,Shang, Dong-Ping,Li, Bao-Sheng,Sun, Tao,Lin, Xiu-Tong,Yin, Yong Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3
Objective: To evaluate the effect of intravenous contrast on dose calculation in radiation treatment planning for oesophageal cancer. Methods: A total of 22 intravein-contrasted patients with oesophageal cancer were included. The Hounsfield unit (HU) value of the enhanced blood stream in thoracic great vessels and heart was overridden with 45 HU to simulate the non-contrast CT image, and 145 HU, 245 HU, 345 HU, and 445 HU to model the different contrast-enhanced scenarios. 1000 HU and -1000 HU were used to evaluate two non-physiologic extreme scenarios. Variation in dose distribution of the different scenarios was calculated to quantify the effect of contrast enhancement. Results: In the contrast-enhanced scenarios, the mean variation in dose for planning target volume (PTV) was less than 1.0%, and those for the total lung and spinal cord were less than 0.5%. When the HU value of the blood stream exceeded 245 the average variation exceeded 1.0% for the heart V40. In the non-physiologic extreme scenarios, the dose variation of PTV was less than 1.0%, while the dose calculations of the organs at risk were greater than 2.0%. Conclusions: The use of contrast agent does not significantly influence dose calculation of PTV, lung and spinal cord. However, it does have influence on dose accuracy for heart.
Fuel Economy Analysis of a Series Hybrid Electric Bus with Low-Speed Shutdown Control Strategy
Xiaogang Wu,Han Chen,Jiuyu Du,Chen Hu 보안공학연구지원센터 2014 International Journal of Control and Automation Vol.7 No.10
The series hybrid electric bus that is demonstrated operating in China has the problem of non-ideal fuel economy for the conventional auxiliary equipment can’t shut down the engine. Based on the series hybrid electric bus using electric auxiliary equipment, a control strategy is proposed based on the combination of engine low-speed shutdown and load following. The main control variables are battery SOC and vehicle speed, and the engine low-speed shutdown is realized. Three different driving cycles are employed: Chinese city driving cycle, Zhuzhou city of Hunan province driving cycle, and Hefei city of Anhui province driving cycle. By using the analysis method of the energy flow diagram, the fuel economy in different driving cycles is compared and analyzed. The simulation results show that the control strategy of the engine low-speed shutdown affects little on fuel economy in different driving cycles. All the fuel-saving ratios of the series hybrid system in different driving cycles can reach above 25%.
Graphite-based selectorless RRAM: improvable intrinsic nonlinearity for array applications
Chen, Ying-Chen,Hu, Szu-Tung,Lin, Chih-Yang,Fowler, Burt,Huang, Hui-Chun,Lin, Chao-Cheng,Kim, Sungjun,Chang, Yao-Feng,Lee, Jack C. The Royal Society of Chemistry 2018 Nanoscale Vol.10 No.33
<P>Selectorless graphite-based resistive random-access memory (RRAM) has been demonstrated by utilizing the intrinsic nonlinear resistive switching (RS) characteristics, without an additional selector or transistor for low-power RRAM array application. The low effective dielectric constant value (<I>k</I>) layer of graphite or graphite oxide is utilized, which is beneficial in suppressing sneak-path currents in the crossbar RRAM array. The tail-bits with low nonlinearity can be manipulated by the positive voltage pulse, which in turn can alleviate variability and reliability issues. Our results provide additional insights for built-in nonlinearity in 1<I>R</I>-only selectorless RRAMs, which are applicable to the low-power memory array, ultrahigh density storage, and in-memory neuromorphic computational configurations.</P>
The Nature of Acid-Catalyzed Acetalization Reaction of 1,2-Propylene Glycol and Acetaldehyde
( Chen Cheng ),( Hui Chen ),( Xia Li ),( Jian Li Hu ),( Bao Chen Liang ) 한국화학공학회 2015 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.53 No.4
We investigated catalytic activity of ion-exchange resins in acetalization of 1,2-propylene glycol with acetaldehyde. The impacts of reaction variables, such as temperature, reaction time, catalyst loading and feedstock composition, on the conversion of 1,2-propylene glycol were measured. The life of the catalyst was also studied. Furthermore, the reaction kinetics of 1,2-propylene glycol acetalization was studied. It was found that reaction rate followed the firstorder kinetics to acetaldehyde and 1,2-propylene glycol, respectively. Therefore, overall acetalization reaction should follow the second-order reaction kinetics, expressed as r=kC pile{nA#A} C pile{nB#B} =19.74 {-6650} over {T} C pile{1#A} C pile{1#B}.
HU CHEN,YUNFEI LIU,YINONG LU,HONGMING WU,HAO QIAN,BAOSHUAI HUANG 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.4
The Eu3+-doped CdTe quantum dots (QDs) have been successfully synthesized in aqueous phase through microwave-assisted hydrothermal method. The as-prepared products were characterized by X-ray diffraction (XRD) technique, high-resolution transmission electron microscope (HRTEM), energy dispersive spectrum (EDS), X-ray photoclectron spectrum (XPS), UV-visble (UV-Vis) absorption spectrum and photoluminescence (PL). As the results show, the average sizes of the cubic phase CdTe and CdTe:1%Eu3+ are an average size of 3.7 nm and 3.5 nm, respectively. The average lattice parameter of CdTe:Eu3+ decreases with increasing Eu3+ ions concentration. Furthermore, compared to green emission of the host CdTe, the CdTe:1%Eu3+ presents additional orange fluorescence emission of Eu3+ ions. Recombination luminescence color is almost located in the yellow region of the CIE 1931, and the CIE 1931 coordinate is (0.448, 0.513). The effect of different Eu3+ doping concentration on the luminescence of CdTe:Eu3+ QDs was discussed in detail. It suggests that CdTe:Eu3+ QDs are potential phosphors for white light-emitting materials.
( Chen Chen ),( Ming Zhong Sun ),( Shu Qing Liu ),( Dong Mei Yeh ),( Li Jun Yu ),( Yang Song ),( Lin Lin Gong ),( Li Hong Hao ),( Jun Hu ),( Shu Juan Shao ) 생화학분자생물학회 (구 한국생화학분자생물학회) 2010 BMB Reports Vol.43 No.8
Smad4 is involved in cancer progression and metastasis. Using a pair of human syngeneic epithelial ovarian cancer cells with low (HO-8910) and high (HO-8910PM) metastatic abilities, we aimed to reveal the role of Smad4 in ovarian cancer metastasis in vitro. Smad4 was down-regulated in HO-8910PM cell line relative to HO-8910 by implicating Smad4 was probably a potential tumor suppressor gene for ovarian cancer. Re-expression of Smad4 decreased the migration ability and inhibited the invasion capacity of HO-8910PM, while promoted the cell adhesion capacity for HO-8910PM. The stable expression of Smad4 increased the expression of E-cadherin, reduced the expression of plasminogen activator inhibitor-1 (PAI-1) and slightly down-regulated the expression of VEGF. Smad4 suppresses human ovarian cancer cell metastasis potential through its effect on the expressions of PAI-1, E-cadherin and VEGF. Results from current work implicate Smad4 might suppress the invasion and metastasis of human ovarian tumor cells through a TGF-β/Smad-mediated pathway. [BMB reports 2010; 43(8): 554-560]
Chen, Jun-Hu,Lu, Feng,Lim, Chae Seung,Kim, Jung-Yeon,Ahn, Heui-June,Suh, In-Bum,Takeo, Satoru,Tsuboi, Takafumi,Sattabongkot, Jetsumon,Han, Eun-Taek Elsevier 2010 Acta tropica Vol.113 No.1
<P><B>Abstract</B></P><P>Loop-mediated isothermal amplification (LAMP) is a novel technique that rapidly amplifies target DNA in isothermal conditions. In a previous study, the sensitivities and specificities of LAMP, microscopy, and nested PCR were compared in the context of rapid malaria detection. In the present study, LAMP detected vivax malaria parasites in 115 of 117 microscopically positive samples (sensitivity, 98.3%; 95% CI, 97.4–100%), which agreed well with the nested PCR results (sensitivity, 99.1%; 95% CI: 96.0–100%). No positive cases of malaria were detected by LAMP or nested PCR in 50 consecutive feverish patients other than malaria from malaria endemic areas. LAMP performed on DNA extracted from heat-treated blood had a sensitivity of 93.3% (28/30, 95% CI: 84.4–100%) and specificity of 100% (30/30, 95% CI: 100%). The present study shows that LAMP based assays have high sensitivity, specificity, and amplification efficiencies for <I>Plasmodium vivax</I> detection. The authors recommend that LAMP can be considered as a rapid nucleic acid amplification assay for the molecular diagnosis of <I>P. vivax</I> in both clinical laboratories and malaria clinics in areas where vivax malaria is endemic.</P>
Hu Hanyu,Shan Weifeng,Tang Yixiang,Heidari Ali Asghar,Chen Huiling,Liu Haijun,Wang Maofa,Escorcia-Gutierrez José,Mansour Romany F,Chen Jun 한국CDE학회 2022 Journal of computational design and engineering Vol.9 No.6
The sine cosine algorithm (SCA) is a metaheuristic algorithm proposed in recent years that does not resort to nature-related metaphors but explores and exploits the search space with the help of two simple mathematical functions of sine and cosine. SCA has fewer parameters and a simple structure and is widely used in various fields. However, it tends to fall into local optimality because it does not have a well-balanced exploitation and exploration phase. Therefore, in this paper, a new, improved SCA algorithm (QCSCA) is proposed to improve the performance of the algorithm by introducing a quick move mechanism and a crisscross mechanism to SCA and adaptively improving one of the parameters. To verify the effectiveness of QCSCA, comparison experiments with some conventional metaheuristic algorithms, advanced metaheuristic algorithms, and SCA variants are conducted on IEEE CEC2017 and CEC2013. The experimental results show a significant improvement in the convergence speed and the ability to jump out of the local optimum of the QCSCA. The scalability of the algorithm is verified in the benchmark function. In addition, QCSCA is applied to 14 real-world datasets from the UCI machine learning database for selecting a subset of near-optimal features, and the experimental results show that QCSCA is still very competitive in feature selection (FS) compared to similar algorithms. Our experimental results and analysis show that QCSCA is an effective method for solving global optimization problems and FS problems.