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RISS 인기검색어
- 검색키워드
- 저자 : Hideaki Motoyama (검색결과 10 건)
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Atsushi Otsuka,Takahisa Suzuki,Yuto Matsushita,Hiromitsu Watanabe,Keita Tamura,Daisuke Motoyama,Toshiki Ito,Takayuki Sugiyama,Hideaki Miyake 대한배뇨장애요실금학회 2019 International Neurourology Journal Vol.23 No.4
Purpose: To evaluate whether hydrodistention with fulguration of Hunner lesions (HD/FUL) plus maintenance dimethyl sulfoxide (DMSO) therapy prolongs the recurrence-free time in patients with Hunner type interstitial cystitis (IC). Methods: The study enrolled patients with Hunner type IC who required repeat HD/FUL due to recurrence of IC symptoms after the first HD/FUL at our institution. All patients received a second HD/FUL plus maintenance DMSO therapy. The maintenance DMSO therapy was performed every 2 weeks for a total of 8 instillations, and then once every 4 weeks thereafter. The recurrencefree time from HD/FUL to therapeutic failure was estimated using the Kaplan-Meier method. The recurrence-free time between the first HD/FUL and second HD/FUL plus maintenance DMSO therapy was statistically compared using the log-rank test. Results: A total of 21 patients (mean age, 66.3±10.8 years) with Hunner type IC were evaluated. The recurrence-free time for the second HD/FUL plus maintenance DMSO therapy was significantly longer than that for the first HD/FUL (P<0.0001). The median recurrence-free time for the first HD/FUL was 10.1 months, while that for the second HD/FUL plus maintenance DMSO therapy has yet to be reached. The recurrence-free rate for the first HD/FUL was 81.0% at 6 months, 38.1% at 1 year, 9.5% at 2 years, and 4.8% at 3 years. In contrast, the rate for the second HD/FUL plus maintenance DMSO therapy was 100% at 6 months, 94.7% at 1 year, 82.6% at 2 years, and 82.6% at 3 years. There were no significant differences in efficacy between the first and second HD/FUL. Conclusions: HD/FUL plus maintenance DMSO therapy clearly prolongs the recurrence-free time compared with HD/FUL alone in Hunner type IC.
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Kotaro Fukui,Yeongcheol Han,허영숙,홍성민,Soon Do Hur,Hideaki Motoyama,Shuji Fujita,Fumio Nakazawa 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.12
The total mercury concentration (HgT) of surface snow samples collected along a ~1500 km transect in east Queen Maud Land was determined using inductively coupled plasma sector field mass spectrometry to address the behavior of Hg on the Antarctic Plateau. Due to the volatile nature of mercury, measures were taken against Hg loss from standard solutions by choosing appropriate container material and stabilizing agents. Glass bottles with Teflon-lined caps were superior to Teflon and polyethylene containers in protecting against Hg loss, but addition of gold chloride (AuCl_3) or bromine chloride (BrCl) was necessary to ensure preservation of Hg. As Hg loss was also observed in snowmelt samples, our analysis may underestimate the actual amount of HgT in the snow. Even so, the measured HgT was still very low (< 0.4-10.8 pg g−¹, n = 44) without a signal of depositional enhancement accompanying photo-oxidation of atmospheric elemental mercury in austral midsummer. Moreover, the dynamic variation along the traverse implies spatial and temporal heterogeneity in its source processes.
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Net deposition of mercury to the Antarctic Plateau enhanced by sea salt
Han, Yeongcheol,Huh, Youngsook,Hur, Soon Do,Hong, Sungmin,Chung, Ji Woong,Motoyama, Hideaki Elsevier 2017 The Science of the total environment Vol.583 No.-
<P><B>Abstract</B></P> <P>Photochemically driven mercury (Hg) exchange between the atmosphere and the Antarctic Plateau snowpack has been observed. An imbalance in bidirectional flux causes a fraction of Hg to remain in the snowpack perennially, but the factors that control the amount of Hg sequestered on the Antarctic Plateau are not fully understood. We analyzed sub-annual variations in total Hg (Hg<SUB>T</SUB>) deposition to Dome Fuji over the period of 1986–2010 using cold vapor inductively coupled plasma mass spectrometry and compared concentrations with those of sea salt components (Na<SUP>+</SUP> and Cl<SUP>−</SUP>). Hg<SUB>T</SUB> ranged from 0.12 to 5.19pgg<SUP>−1</SUP> (n=78) and was relatively high when the Na<SUP>+</SUP> concentrations were high in the same or underlying snow layers. A significant correlation (r=0.7) was found between the annual deposition fluxes of Hg<SUB>T</SUB> and Na<SUP>+</SUP>. Despite different origins and behavior of Hg and sea salt, the near-synchronous increases in the concentrations and correlation between the fluxes suggest that sea salt can intervene in the air-snow Hg exchange and promote the net deposition of Hg in the Antarctic Plateau.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Sub-annual variations in Hg deposition were reconstructed from Dome Fuji snowpack. </LI> <LI> Cold vapor ICP-SFMS was applied to resolve a difference of sub-pg Hg g<SUP>−1</SUP>. </LI> <LI> Increased concentrations of Hg and Na<SUP>+</SUP> were near-synchronous. </LI> <LI> A significant correlation was found between their annual deposition fluxes. </LI> <LI> Sea salt can control the net Hg deposition to the Antarctic Plateau. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
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Hwang, Heejin,Hur, Soon Do,Lee, Jeonghoon,Han, Yeongcheol,Hong, Sungmin,Motoyama, Hideaki Elsevier 2019 Science of the Total Environment Vol.669 No.-
<P><B>Abstract</B></P> <P>Anthropogenic plutonium (Pu) in the environment is a result of atmospheric nuclear testing during the second half of the 20th century. In this work, we analyzed a 4-meter deep Antarctic Plateau snowpack characterized by a low snow accumulation rate and negligible snow impurities. These sample conditions enabled us to measure the snowpack Pu fallout by applying inductively coupled plasma sector field mass spectrometry to a few mL of snow melt without purification or preconcentration. Pu concentrations in the reconstructed Pu fallout record for the period after 1956 CE increased and decreased in agreement with past atmospheric nuclear testing. Two peaks and two dips associable with historical events were observed, and the highest peak in 1964(±1) CE approximately coincided with the maximum concentration of non-sea-salt sulfate caused by the Mt. Agung eruption in 1963 CE. Enhanced Pu fallout in the 1970s was attributed the geographical proximity of the Southern Hemispheric nuclear test sites. Our results suggest that by improving the instrumental sensitivity and precision, the potential of the Antarctic ice sheet as an archive of Pu fallout can be further explored and utilized for understanding atmospheric dispersion and for dating ice cores.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Atmospheric nuclear explosions in 1940–1980 caused global dispersion of plutonium. </LI> <LI> ICP-SFMS detected fallout <SUP>239</SUP>Pu from only a few grams of Antarctic Plateau snow. </LI> <LI> Purification and preconcentration of Pu were not necessary. </LI> <LI> Reconstructed <SUP>239</SUP>Pu fallout agreed with atmospheric nuclear explosion history. </LI> <LI> Potential of Pu as an atmospheric tracer and an age marker can be further utilized. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
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Han, Yeong-Cheol,Huh, Young-Sook,Hong, Sung-Min,Hur, Soon-Do,Motoyama, Hideaki,Fujita, Shuji,Nakazawa, Fumio,Fukui, Kotaro Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.12
The total mercury concentration ($Hg_T$) of surface snow samples collected along a ~1500 km transect in east Queen Maud Land was determined using inductively coupled plasma sector field mass spectrometry to address the behavior of Hg on the Antarctic Plateau. Due to the volatile nature of mercury, measures were taken against Hg loss from standard solutions by choosing appropriate container material and stabilizing agents. Glass bottles with Teflon-lined caps were superior to Teflon and polyethylene containers in protecting against Hg loss, but addition of gold chloride ($AuCl_3$) or bromine chloride (BrCl) was necessary to ensure preservation of Hg. As Hg loss was also observed in snowmelt samples, our analysis may underestimate the actual amount of HgT in the snow. Even so, the measured HgT was still very low (< 0.4-10.8 pg $g^{-1}$, n = 44) without a signal of depositional enhancement accompanying photo-oxidation of atmospheric elemental mercury in austral midsummer. Moreover, the dynamic variation along the traverse implies spatial and temporal heterogeneity in its source processes.
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Advancements and Challenges in Robot-Assisted Bone Processing in Neurosurgical Procedures
Yoshihiro Kitahama,Hiroo Shizuka,Yuto Nakano,Yukoh Ohara,Jun Muto,Shuntaro Tsuchida,Daisuke Motoyama,Hideaki Miyake,Katsuhiko Sakai 대한척추신경외과학회 2024 Neurospine Vol.21 No.1
Objective: Practical applications of nerve decompression using neurosurgical robots remain unexplored. Our ongoing research and development initiatives, utilizing industrial robots, aim to establish a secure and efficient neurosurgical robotic system. The principal objective of this study was to automate bone grinding, which is a pivotal component of neurosurgical procedures. Methods: To achieve this goal, we integrated an endoscope system into a manipulator and conducted precision bone machining using a neurosurgical drill, recording the grinding resistance values across 3 axes. Our study encompassed 2 core tasks: linear grinding, such as laminectomy, and cylindrical grinding, such as foraminotomy, with each task yielding unique measurement data. Results: In linear grinding, we observed a proportional increase in grinding resistance values in the machining direction with acceleration. This observation suggests that 3-axis resistance measurements are a valuable tool for gauging and predicting deep cortical penetration. However, problems occurred in cylindrical grinding, and a significant error of 10% was detected. The analysis revealed that multiple factors, including the tool tip efficiency, machining speed, teaching methods, and deflection in the robot arm and jig joints, contributed to this error. Conclusion: We successfully measured the resistance exerted on the tool tip during bone machining with a robotic arm across 3 axes. The resistance ranged from 3 to 8 Nm, with the measurement conducted at a processing speed approximately twice that of manual surgery performed by a surgeon. During the simulation of foraminotomy under endoscopic grinding conditions, we encountered a -10% error margin.
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