农村公共仪式与乡村公共性重建 —以中国东北农村A村的“祈雨祭”为中心

Lu Heng,Yang Liu 부산대학교 중국연구소 2018 Journal of China Studies Vol.21 No.1

In 21th century, China's rural areas were impacted by urbanization and industrialization. A general consent is made by many Chinese scholars that China is facing the “end of villages”. On the basis of the scholars' concern about the public reconstruction of the rural areas in the southeast of China, through a long-term field work in village A, a less developed country in the northeast of China, this paper puts more attention to the rural villages in the northeast of China with less clan tradition which are neglected by scholars. This paper analyzes the relationship between rural public ceremony and publicness reconstruction with two components of public beliefs and public rules, on the basis of Victor Turner's “Social Drama Theory” on public ceremony. Public beliefs and public rules are reflected in the A village's well-preserved public ritual of “praying for rain”. The ceremony of praying for rain is a traditional way for Chinese people to ask for rain from Gods when drought is severely happening. And the public beliefs which are based on the folklore religion of A village, are especially embodied in village temple belief, folk Buddhism and magic belief. Public rules are mainly embodied in the process of ritual, which is divided into separation stage, liminal stage and reintegration stage. And there are special behavior of villagers for each stage. During separation stage, people make Gods happy with some ways, and make themselves suffered to plead. and sacrifice to Gods. During liminal stage, people think that Gods heared of their prays and will reward to them. During reintegration stage, it is a kind of spiritual rebirth for the villagers who take part in the ceremony of rain offering. Public beliefs and public rules are complementary relations. Public beliefs lay the ideological foundation for the implementation of public rules, and public rules deepen people's public beliefs. Thus, the publicness of the A village was strengthened through the ceremony of “praying for rain”. And these two factors also play an essential role in strengthening villagers' interaction, rallying identity, shaping public space and rebuilding publicity. Finally, another result is emphasized that the public ceremony has a historical continuity of form and function while facing background of reflecting on Chinese “rural hollowing” problem’s singularity based on the ontological basis of historical continuity, which emphasize unity of all things in the world. Compared with urban publicness, public beliefs and public rules are significant ,both of theoretically and practically, significance for the reconstruction of rural publicness. In 21th century, China's rural areas were impacted by urbanization and industrialization. A general consent is made by many Chinese scholars that China is facing the “end of villages”. On the basis of the scholars' concern about the public reconstruction of the rural areas in the southeast of China, through a long-term field work in village A, a less developed country in the northeast of China, this paper puts more attention to the rural villages in the northeast of China with less clan tradition which are neglected by scholars. This paper analyzes the relationship between rural public ceremony and publicness reconstruction with two components of public beliefs and public rules, on the basis of Victor Turner's “Social Drama Theory” on public ceremony. Public beliefs and public rules are reflected in the A village's well-preserved public ritual of “praying for rain”. The ceremony of praying for rain is a traditional way for Chinese people to ask for rain from Gods when drought is severely happening. And the public beliefs which are based on the folklore religion of A village, are especially embodied in village temple belief, folk Buddhism and magic belief. Public rules are mainly embodied in the process of ritual, which is divided into separation stage, liminal stage and reintegration stage. And there are special behavior of villagers for each stage. During separation stage, people make Gods happy with some ways, and make themselves suffered to plead. and sacrifice to Gods. During liminal stage, people think that Gods heared of their prays and will reward to them. During reintegration stage, it is a kind of spiritual rebirth for the villagers who take part in the ceremony of rain offering. Public beliefs and public rules arecomplementary relations. Public beliefs lay the ideological foundation for the implementation of public rules, and public rules deepen people's public beliefs. Thus, the publicness of the A village was strengthened through the ceremony of “praying for rain”. And these two factors also play an essential role in strengthening villagers' interaction, rallying identity, shaping public space and rebuilding publicity. Finally, another result is emphasized that the public ceremony has a historical continuity of form and function while facing background of reflecting on Chinese “rural hollowing” problem’s singularity based on the ontological basis of historical continuity, which emphasize unity of all things in the world. Compared with urban publicness, public beliefs and public rules are significant ,both of theoretically and practically, significance for the reconstruction of rural publicness.

Load Sharing Performance of Herringbone Planetary Gear System with Flexible Pin

Chang-lu Wang,Jing Wei,Zi-heng Wu,Long Lu,Hao Gao 한국정밀공학회 2019 International Journal of Precision Engineering and Vol.20 No.12

To study the load distribution mechanism of the power-split transmission, and improve the carrying capacity of the herringbone star gear transmission system, the dynamic model of the planetary gear system for a geared turbofan engine with the flexible pin was established based on the node finite element method. The model considered the comprehensive influence of meshing error, time-varying meshing stiffness, bearing supporting stiffness and meshing phase. The dynamic load sharing performance of the system were studied in the equivalent meshing error, and the influence of the error incentives and structure of pins on the load sharing characteristics was analyzed. The results indicate that the vibration track of the center gears deviates from the origin because of the eccentricity error. The load sharing performance of the system can be improved by improving gears’ manufacturing precision. Moreover, the influence of manufacturing errors is larger than that of assembling errors. The flexible pin improved by Montestruc has the best load sharing performance among the four types of pin models designed in the study. The load sharing performance declines with an increase of in input speed and a decrease in input power.

Ten-eleven translocation 1 mediating DNA demethylation regulates the proliferation of chicken primordial germ cells through the activation of Wnt4/β-catenin signaling pathway

Lu Yinglin,Li Ming,Cao Heng,Zhou Jing,Li Fan,Yu Debing,Yu Minli 아세아·태평양축산학회 2024 Animal Bioscience Vol.37 No.3

Objective: The objective of this study was to investigate the regulation relationship of Teneleven translocation 1 (Tet1) in DNA demethylation and the proliferation of primordial germ cells (PGCs) in chickens. Methods: siRNA targeting Tet1 was used to transiently knockdown the expression of Tet1 in chicken PGCs, and the genomic DNA methylation status was measured. The proliferation of chicken PGCs was detected by flow cytometry analysis and cell counting kit-8 assay when activation or inhibition of Wnt4/β-catenin signaling pathway. And the level of DNA methylation and hisotne methylation was also tested. Results: Results revealed that knockdown of Tet1 inhibited the proliferation of chicken PGCs and downregulated the mRNA expression of Cyclin D1 and cyclin-dependent kinase 6 (CDK6), as well as pluripotency-associated genes (Nanog, PouV, and Sox2). Flow cytometry analysis confirmed that the population of PGCs in Tet1 knockdown group displayed a significant decrease in the proportion of S and G2 phase cells, which meant that there were less PGCs entered the mitosis process than that of control. Furthermore, Tet1 knockdown delayed the entrance to G1/S phase and this inhibition was rescued by treated with BIO. Consistent with these findings, Wnt/β-catenin signaling was inactivated in Tet1 knockdown PGCs, leading to aberrant proliferation. Further analysis showed that the methylation of the whole genome increased significantly after Tet1 downregulation, while hydroxymethylation obviously declined. Meanwhile, the level of H3K27me3 was upregulated and H3K9me2 was downregulated in Tet1 knockdown PGCs, which was achieved by regulating Wnt/β-catenin signaling pathway. Conclusion: These results suggested that the self-renewal of chicken PGCs and the maintenance of their characteristics were regulated by Tet1 mediating DNA demethylation through the activation of Wnt4/β-catenin signaling pathway.

Transcarotid Mechanical Thrombectomy for Embolic Intracranial Large Vessel Occlusion after Endovascular Deconstructice Embolization for Carotid Blowout Syndrome

Lu Chi-Ju,Lin Yen-Heng,Lee Chung-Wei 대한신경중재치료의학회 2020 Neurointervention Vol.15 No.1

Carotid blowout syndrome (CBS) is a fatal complication of head and neck cancer. Endovascular treatment, particularly deconstructive embolization, is effective for CBS, but it might result in thromboembolic events. We report the case of a 57-year-old man with underlying recurrent head and neck cancer who had CBS. The patient received endovascular embolization of the right internal, external, and common carotid arteries. Right internal carotid artery to middle cerebral artery embolic occlusion was noted immediately after the procedure, and left-sided weakness and facial palsy were found. Ipsilateral suprabulbar cervical internal carotid artery puncture was performed under fluoroscopic guidance, and rescue suction thrombectomy was successful. The patient had no significant neurological sequela. Transcarotid intraarterial thrombectomy is a reasonable method for managing postembolization large vessel occlusion, even in the neck, after irradiation.

Estrogen Receptor Alpha Gene Polymorphisms and Breast Cancer Risk: a Case-control Study with Meta-analysis Combined

Lu, Hong,Chen, Dong,Hu, Li-Ping,Zhou, Lian-Lian,Xu, Hui-Ying,Bai, Yong-Heng,Lin, Xiang-Yang Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11

Molecular epidemiological studies have shown that gene polymorphisms of estrogen receptor alpha gene (ESR-${\alpha}$) are associated with breast cancer risk. However, previous results from many molecular studies have been inconsistent. In this study, we examined two polymorphisms (PvuII and XbaI RFLPs) of the ESR-${\alpha}$ gene in 542 breast cancer cases and 1,016 controls from China. Associations between the polymorphisms and breast cancer risk were calculated with an unconditional logistic regression model. Linkage disequilibrium and haplotypes were analyzed with the SHEsis software. In addition, we also performed a systematic meta-analysis of 24 published studies evaluating the association. No significant associations were found between the PvuII polymorphism and breast cancer risk. However, a significantly decreased risk of breast cancer was observed among carriers of the XbaI 'G' allele (age-adjusted OR = 0.80; 95% CI = 0.66- 0.97) compared with carriers of the 'A' allele. Haplotype analysis showed significantly decreased cancer risk for carriers of the 'CG' haplotype (OR = 0.79; 95% CI = 0.66- 0.96). In the systematic meta-analysis, the XbaI 'G' allele was associated with an overall significantly decreased risk of breast cancer (OR = 0.90, 95% CI = 0.82- 1.00). In addition, the PvuII 'C' allele showed a 0.96- fold decreased disease risk (95% CI = 0.92- 0.99). In subgroup analysis, an association between the PvuII 'C' and XbaI 'G' alleles and breast cancer risk was significant in Asians ('C' vs. 'T': OR = 0.93, 95% CI = 0.85- 1.00; 'G' vs. 'A': OR = 0.82, 95% CI = 0.68- 0.98), but not in Euro-Americans. Thus, our results provide evidence that ESR-${\alpha}$ polymorphisms are associated with susceptibility to breast cancer. These associations may largely depend on population characteristics and geographic location.

Ginseng-plus-Bai-Hu-Tang ameliorates diet-induced obesity, hepatic steatosis, and insulin resistance in mice

Lu, Hsu-Feng,Lai, Yu-Heng,Huang, Hsiu-Chen,Lee, I-Jung,Lin, Lie-Chwen,Liu, Hui-Kang,Tien, Hsiao-Hsuan,Huang, Cheng The Korean Society of Ginseng 2020 Journal of Ginseng Research Vol.44 No.2

Background: Dietary fat has been suggested to be the cause of various health issues. Obesity, hypertension, cardiovascular disease, diabetes, dyslipidemia, and kidney disease are known to be associated with a high-fat diet (HFD). Obesity and associated conditions, such as type 2 diabetes mellitus and nonalcoholic fatty liver disease (NAFLD), are currently a worldwide health problem. Few prospective pharmaceutical therapies that directly target NAFLD are available at present. A Traditional Chinese Medicine, ginseng-plus-Bai-Hu-Tang (GBHT), is widely used by diabetic patients to control glucose level or thirst. However, whether it has therapeutic effects on fat-induced hepatic steatosis and metabolic syndrome remains unclear. Methods: This study was conducted to examine the therapeutic effect of GBHT on fat-induced obesity, hepatic steatosis, and insulin resistance in mice. Results: GBHT protected mice against HFD-induced body weight gain, hyperlipidemia, and hyperglycemia compared with mice that were not treated. GBHT inhibited the expansion of adipose tissue and adipocyte hypertrophy. No ectopic fat deposition was found in the livers of HFD mice treated with GBHT. In addition, glucose intolerance and insulin sensitivity in HFD mice was also improved by GBHT. Conclusion: GBHT prevents changes in lipid and carbohydrate metabolism in a HFD mouse model. Our findings provide evidence for the traditional use of GBHT as therapy for the management of metabolic syndrome.

Breast Cancer Inpatients Undergoing Mastectomy from a Hospital in Guangzhou, China: A Retrospective Analysis 2004-2013

Lu, Jian-Jun,Li, Heng-Ai,Xiong, Ying Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.11

Background: To explore the hospitalizations of breast cancer patients undergoing mastectomy, and to provide a basis for management, clinical prevention and treatment. Materials and Methods: We conducted an investigation by means of the retrospective survey and the medical records retrieval system, and made out the data of patients suffered from breast cancer in a hospital in Guangzhou from 2004 to 2013, including age, medical payment methods, pathological type, treatment, treatment results, complications, hospitalization days, cost and so on. Results: The average age of the inpatients was 50.14 years old. The main histologic types were infiltrating duct carcinoma (88.06%). The main surgery was modified radical mastectomy (80.41%). The cure rate was 90.80% during the 10 years. The main medical payment method was self-paying (57.28%). The average hospital stay was 13.51 days, and average hospitalization cost was RMB 23,083.66 yuan, proportion of drug fees up to 39.70%. Postoperative complication rate was 0.79%. The self-paying group was with the highest proportion of drug fees (P<0.05), while the free medical service group was with the longest hospitalization days (P<0.05). Conclusions: The payment methods significantly affected the proportion of drug fees and hospitalization days. The therapeutic effect was satisfactory with less complications and reasonable proportion of drug fees in our hospital.

Cancer Research Advances Regarding the CKLF-like MARVEL Transmembrane Domain Containing Family

Lu, Jia,Wu, Qian-Qian,Zhou, Ya-Bo,Zhang, Kai-Hua,Pang, Bing-Xin,Li, Liang,Sun, Nan,Wang, Heng-Shu,Zhang, Song,Li, Wen-Jian,Zheng, Wei,Liu, Wei Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.6

The CKLF-like MARVEL transmembrane domain-containing family (CMTM) is a novel family of genes first reported at international level by Peking University Human Disease Gene Research Center. The gene products act between chemokines and the transmembrane-4 superfamily. Located in several human chromosomes, the CMTMs CKLF and CMTM1 to CMTM8 may be unregulated in tumors and act as potential tumor suppressor genes with important roles in the immune, male reproductive and hematopoietic systems. In-depth studies in recent years established a close relation between CMTMs and tumorigenesis and metastasis. The CMTM family has a significant clinical value in diagnosis and treatment of diseases linked to tumors and the immune system.

A systematic review and network meta-analysis of biomedical Mg alloy and surface coatings in orthopedic application

XinYue Lu,HongXin Cai,Yu Ru Li,Xinru Zheng,Jiahao Yun,Wenhui Li,Xiaoyu Geng,Jae-Sung Kwon,Heng Bo Jiang 대한치과재료학회 2021 대한치과기재학회 학술대회 Vol.2021 No.11

A Novel Monoclonal Antibody Induces Cancer Cell Apoptosis and Enhances the Activity of Chemotherapeutic Drugs

Xu, Heng,Tian, Yan-Na,Dun, Bo-Ying,Liu, Hai-Tao,Dong, Guang-Kuo,Wang, Jin-Hua,Lu, Shang-Su,Chen, Bo,She, Jin-Xiong Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.11

A novel monoclonal antibody (mAb), known as AC10364, was identified from an antibody library generated by immunization of mice with human carcinoma cells. The mAb recognized proteins in lysates from multiple carcinoma cell lines. Cell cytotoxicity assays showed that AC10364 significantly inhibited cell growth and induced apoptosis in multiple carcinoma cell lines, including Bel/fu, KATO-III and A2780. Compared with mAb AC10364 or chemotherapeutic drugs alone, the combination of mAb AC10364 with chemotherapeutic drugs demonstrated enhanced growth inhibitory effects on carcinoma cells. These results suggest that mAb AC10364 is a promising candidate for cancer therapy.