http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
HDAC-targeting epigenetic drug screening for biliary tract cancer
Christian MAYR,Tobias KIESSLICH,Sara ERBER,Dino BEKRIC,Heidemarie DOBIAS,Markus RITTER,Tarkan JAGER,Bettina NEUMAYER,Paul WINKELMANN,Eckhard KLIESER,Daniel NEUREITER 한국간담췌외과학회 2021 Annals of hepato-biliary-pancreatic surgery Vol.25 No.-
HDAC-Targeting Epigenetic Drug Screening for Biliary Tract Cancer
( Christian Mayr ),( Tobias Kiesslich ),( Sara Erber ),( Dino Bekric ),( Heidemarie Dobias ),( Markus Ritter ),( Tarkan Jäger ),( Bettina Neumayer ),( Paul Winkelmann ),( Eckhard Klieser ),( Daniel Ne 대한간학회 2021 춘·추계 학술대회 (KASL) Vol.2021 No.1
Tobias Graf,Jan-Frederik Güth,Christian Diegritz,Anja Liebermann,Josef Schweiger,Oliver Schubert 대한치과보철학회 2021 The Journal of Advanced Prosthodontics Vol.13 No.6
PURPOSE. The aim of this study was to evaluate the efficiency of occlusal and interproximal adjustments of single implant crowns (SIC), comparing a digital cast-free approach (CF) and a protocol using 3D printed casts (PC). MATERIALS AND METHODS. A titanium implant was inserted at position of lower right first molar in a typodont. The implant position was scanned using an intraoral scanner and SICs were fabricated accordingly. Ten crowns (CF; n = 10) were subject to a digital cast-free workflow without any labside occlusal and interproximal modifications. Ten other identical crowns (PC) were adjusted to 3D printed casts before delivery. All crowns were then adapted to the testing model, simulating chair-side adjustments during clinical placement. Adjustment time, quantity of adjustments, and contact relationship were assessed. Data were analyzed using SPSS software (P < .05). RESULTS. Median and interquartile range (IQR) of clinical adjustment time was 02:44 (IQR 00:45) minutes in group CF and 01:46 (IQR 00:21) minutes in group PC. Laboratory and clinical adjustment time in group PC was 04:25 (IQR 00:59) minutes in total. Mean and standard deviation (±SD) of root mean squared error (RMSE) of quantity of clinical adjustments was 45 ± 7 μm in group CF and 34 ± 6 μm in group PC. RMSE of total adjustments was 61 ± 11 μm in group PC. Quality of occlusal contacts was better in group CF. CONCLUSION. Time effort for clinical adjustments was higher in the cast-free protocol, whereas quantity of modifications was lower, and the occlusal contact relationship was found more favourable.
kai tobias block,Hersh Chandarana1,Sarah Milla,Mary Bruno,Tom Mulholland,Girish Fatterpekar,Mari Hagiwara,Robert Grimm,Christian Geppert,Berthold Kiefer 대한자기공명의과학회 2014 Investigative Magnetic Resonance Imaging Vol.18 No.2
Purpose : To describe how a robust implementation of a radial 3D gradient-echo sequence with stack-of-stars samplingcan be achieved, to review the imaging properties of radial acquisitions, and to share the experience from more than5000 clinical patient scans. Materials and Methods: A radial stack-of-stars sequence was implemented and installed on 9 clinical MR systems operatingat 1.5 and 3 Tesla. Protocols were designed for various applications in which motion artifacts frequently pose a problemwith conventional Cartesian techniques. Radial scans were added to routine examinations without selection of specificpatient cohorts. Results: Radial acquisitions show significantly lower sensitivity to motion and allow examinations during free breathing. Elimination of breath-holding reduces failure rates for non-compliant patients and enables imaging at higher resolution. Residual artifacts appear as streaks, which are easy to identify and rarely obscure diagnostic information. The improvedrobustness comes at the expense of longer scan durations, the requirement for fat suppression, and the nonexistence of atime-to-center value. Care needs to be taken during the configuration of receive coils. Conclusion: Routine clinical use of radial stack-of-stars sequences is feasible with current MR systems and may serve assubstitute for conventional fat-suppressed T1-weighted protocols in applications where motion is likely to degrade theimage quality
Block, Kai Tobias,Chandarana, Hersh,Milla, Sarah,Bruno, Mary,Mulholland, Tom,Fatterpekar, Girish,Hagiwara, Mari,Grimm, Robert,Geppert, Christian,Kiefer, Berthold,Sodickson, Daniel K. Korean Society of Magnetic Resonance in Medicine 2014 Investigative Magnetic Resonance Imaging Vol.18 No.2
Purpose : To describe how a robust implementation of a radial 3D gradient-echo sequence with stack-of-stars sampling can be achieved, to review the imaging properties of radial acquisitions, and to share the experience from more than 5000 clinical patient scans. Materials and Methods: A radial stack-of-stars sequence was implemented and installed on 9 clinical MR systems operating at 1.5 and 3 Tesla. Protocols were designed for various applications in which motion artifacts frequently pose a problem with conventional Cartesian techniques. Radial scans were added to routine examinations without selection of specific patient cohorts. Results: Radial acquisitions show significantly lower sensitivity to motion and allow examinations during free breathing. Elimination of breath-holding reduces failure rates for non-compliant patients and enables imaging at higher resolution. Residual artifacts appear as streaks, which are easy to identify and rarely obscure diagnostic information. The improved robustness comes at the expense of longer scan durations, the requirement for fat suppression, and the nonexistence of a time-to-center value. Care needs to be taken during the configuration of receive coils. Conclusion: Routine clinical use of radial stack-of-stars sequences is feasible with current MR systems and may serve as substitute for conventional fat-suppressed T1-weighted protocols in applications where motion is likely to degrade the image quality.
Integration of a deep-learning-based fire model into a global land surface model
Rackhun Son,Tobias Stacke,Veronika Gayler,Julia E.M.S. Nabel,Reiner Schnur,Lazaro Alonso,Christian Requena-Mesa,Alexander J. Winkler,Stijn Hantson,Sonke Zaehle,Ulrich Weber,Nuno Carvalhais 한국기상학회 2023 한국기상학회 학술대회 논문집 Vol.2023 No.10
Integration of a deep-learning-based fire model into a global land surface model
Rackhun Son,Tobias Stacke,Veronika Gayler,Julia E.M.S. Nabel,Reiner Schnur,Lazaro Alonso,Christian Requena-Mesa,Alexander J. Winkler,Stijn Hantson,Sonke Zaehle,Ulrich Weber,Nuno Carvalhais 한국기상학회 2023 한국기상학회 학술대회 논문집 Vol.2023 No.11
Jan Oliver Voss,Tobias Dieke,Christian Doll,Claudia Sachse,Katja Nelson,Jan-Dirk Raguse,Susanne Nahles 대한치주과학회 2016 Journal of Periodontal & Implant Science Vol.46 No.2
Purpose: The goal of this study was to evaluate the long-term success of horizontal alveolar crest augmentation of the retromolar region of the mandible with particulated bone, as well as factors affecting subsequent peri-implant bone loss. Methods: A total of 109 patients (68 female, 41 male) suffering from alveolar ridge deficiencies of the maxilla and mandible were included in this study. All patients were treated with particulated retromolar bone grafts from the mandible prior to the insertion of endosseous dental implants. Mesial and distal peri-implant crestal bone changes were assessed at six time points. Several parameters, including implant survival and the influence of age, gender, localisation of the implant, diameter, covering procedures, and time points of implant placement, were analysed to identify associations with bone level changes using the Mann-Whitney U-test, the Kruskal-Wallis test, and Spearman’s rank-order correlation coefficient. Results: A total of 164 dental implants were placed in the maxilla (n=97) and in the mandible (n=67). The mean observation period was 105.26 ± 21.58 months after implantation. The overall survival rate was 97.6% after 10 years. Overall, peri-implant bone loss was highest during the first year, but decreased over time. The mean amount of bone loss after 10 years was 2.47 mm mesially and 2.50 mm distally. Bone loss was significantly influenced by implant type and primary stability. Conclusions: The use of particulated autologous retromolar bone grafts is a reliable technique for the horizontal reconstruction of local alveolar ridge deficiencies. Our results demonstrate that implants placed in augmented bone demonstrated similar bone level changes compared to implants inserted in non-augmented regions.
Voss, Jan Oliver,Dieke, Tobias,Doll, Christian,Sachse, Claudia,Nelson, Katja,Raguse, Jan-Dirk,Nahles, Susanne Korean Academy of Periodontology 2016 Journal of Periodontal & Implant Science Vol.46 No.2
Purpose: The goal of this study was to evaluate the long-term success of horizontal alveolar crest augmentation of the retromolar region of the mandible with particulated bone, as well as factors affecting subsequent peri-implant bone loss. Methods: A total of 109 patients (68 female, 41 male) suffering from alveolar ridge deficiencies of the maxilla and mandible were included in this study. All patients were treated with particulated retromolar bone grafts from the mandible prior to the insertion of endosseous dental implants. Mesial and distal peri-implant crestal bone changes were assessed at six time points. Several parameters, including implant survival and the influence of age, gender, localisation of the implant, diameter, covering procedures, and time points of implant placement, were analysed to identify associations with bone level changes using the Mann-Whitney U-test, the Kruskal-Wallis test, and Spearman's rank-order correlation coefficient. Results: A total of 164 dental implants were placed in the maxilla (n=97) and in the mandible (n=67). The mean observation period was $105.26{\pm}21.58$ months after implantation. The overall survival rate was 97.6% after 10 years. Overall, peri-implant bone loss was highest during the first year, but decreased over time. The mean amount of bone loss after 10 years was 2.47 mm mesially and 2.50 mm distally. Bone loss was significantly influenced by implant type and primary stability. Conclusions: The use of particulated autologous retromolar bone grafts is a reliable technique for the horizontal reconstruction of local alveolar ridge deficiencies. Our results demonstrate that implants placed in augmented bone demonstrated similar bone level changes compared to implants inserted in non-augmented regions.