전기화상후 Prostaglandin F2a와 Thromboxane B2의 증가에 대한 Flurbiprofen, Prednisolone 및 Gabexate mesilate의 억제효과

조병채,김인규,변진석,백봉수 大韓成形外科學會 1991 Archives of Plastic Surgery Vol.18 No.1

This study was conducted to clarify the inhibitory effect of flurbiprofen, prednisolone, and gabexate mesilate on the synthesis of prostaglandin F2a and thromboxane B2 in the tissue of electrical burn. one hundred sixty Sprague-Dawley rats, 250gm of body weight in average, were divided into 4 groups of control, flurbiprofen, prednisolone and gabexate mesilate administred group. Fourty rats of the each group were subdivided into 1st, 2nd, 4th, 7th postburn day with 10 rats in each subgroup. Ten rats were used for normal values of prostaglandin F2a and thromboxane B2. Flurbiprodfen 30mg/kg was given per mouth, and prednisolone acetate 5mg/kg and gabaxate mesilate 50mg/kg were administred intramuscularly 5 minutes after burn injury and then once a day. All but bone tissue of within 2cm area of the current entry were harvested and ground into homogenate. The levels of prostaglandin F2a and thromoboxane B2 were measured by Radioimmunoassay. The results were as followings: In normal rat tissue, the level of prostagland F2a and thromboxane B2 were 15.8±1.8 and 17.6±2.8ng/mg protein in each. In the control group the levels of both prostaglandin F2a and thromboxane B2 increased abruptly to 5 times and 7 thimes in the first day and maintained the same level in the second day. After then they rapidly decreased and returned to a near normal level in the fourth day. The increase of thromboxane B2 was more remarkable than that of prostaglandin F2a. In the flurbiprofen group, the level of thromboxane B2 was not inerease but kept at a normal level. The average level of prostaglandin F2a in the post-burn first and second day was 59.5% lower than of the control group. The average level on the post-burn first and second day was 61% lower in thromboxane B2 and 33% lower in prostaglandin F2a in the prednisolone group, and 68% lower in throboxane B2 and 48% lower in prostaglandin F2a in the gabexate mesilate group, compared to the control group. These findings suggest that electrically injured tissue is vigrously progressive due to rapid increase of thromboxane B2 and prostaglandin F2a, as inflammatory mediators, in the post-burn first and second day, is nonprogressive after the post-burn fourth day. The flurbiprodfen was the most effective of the three drugs(flurbiprofen, gabexate mesilate, prednisolone in order of effectiveness) to suppress the synthesis of thromboxane B2 prostaglandin F2a of the electrieally injured tissue.

무역-환경연계 논의와 기업의 대응

조원권,성봉석 우송대학교 부설 산업연구원 1999 산업연구 Vol.1 No.2

Conflicts between the liberalization of trade, as promoted by the World Trade Organization, and demand for environmental protection, as promoted by the Multinational Environmental Agreements including developed countries and NGOs, have a serious effect upon business community. This paper examines the essential issues raised in the trade-environment debate within WTO and MEAs, with some case analysis as to how and why problems have arisen. A study of the effect of environmental policies on firms' competitiveness concludes that there is a win-win relationship. Finally, this paper makes proposals as to how firm response to environmental challenges for sustainable development and survival.

복합열화환경하에서의 중성화 및 염화물이온 확산특성이 철근부식에 미치는 영향에 관한 실험적 연구

조봉석,장재봉,김재환,김용로,권영진,김무한 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

It is recognized that reinforcement corrosion is the main distress behind the present concern regarding concrete durability. In this study, to confirm corrosion of reinforced concrete due to permeability of carbonation and chloride ion affected by thickness of cover, kinds of surface coating, measured electric potential, ratio of corrosion area, weight reduction, corrosion velocity of steel bar under environment of complex deterioration. The results showed that an increase in age also decreases Carbonation velocity coefficients and increases Chloride ion diffusion coefficients. As well, an increase in age also increases corrosion of reinforcement due to permeability of carbonation and chloride ion. Corrosion of reinforcement by thickness of cover is superior to 10mm thick than 20mm thick. It showed that an increase in thickness of cover prevent steel bar from deteriorating due to permeability of carbonation and chloride ion. The results of this study showed that corrosion velocity was affected by thickness of cover, kinds of surface coating. data on the development of corrosion velocity made with none, organic B, organic A, inorganic B. and inorganic A is shown.

뿜칠시공에 의한 단면복구재의 시공성 및 공학적 특성에 관한 실험적 연구

조봉석,김영선,장재봉,김용로,김경덕,김무한 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1

These days, serious concerns of reinforced concrete have been raised recently over steel-bar corrosion, cracking, the deterioration of durability and structural stress resistance and so on, all due to the effects of exterior factors. Such being the case, in domestic, various repair materials and method systems to keep up with these reinforced concrete deteriorated due to salt damage, carbonation, chemical decay et. developed and applied. However, on-site quality control of various repair materials and method systems isn't achieved desirably because it is depend completely on a men of experience' opinions above all else regardless of various on - site environments. In this background, mock up test with due regard to real on-site environments was performed to secure fundamental data for establishment of desirable on-site quality control. Mock up test using repair mortar analyzed from angles of construction methods, mechanical spraying pressures, W 1M. Construction methods were designed manpower method and spraying method, spraying pressures were designed 32, 42, 52 psi, W/M were designed 14.4, 15.4, 16.4 %. And compressive strength, Chloride ion diffusion coefficient, bond strength, SEM of mock up test specimens were evaluated. In conclusion, we confirmed excellency of mechanical spraying pressures, fined extremely excellency of condition of spraying pressure 42 ps, W/M 14.4% within this study. therefore the results of this study will be useful to provide fundamental data for establishment of desirable on-site quality control.

전두근ㆍ근막피판을 이용한 선천성 안검하수의 교정

변진석,조병채,백봉수 大韓成形外科學會 1991 Archives of Plastic Surgery Vol.18 No.1

Ptosis of the upper eyelid is one of common deformities of the eye region. To obtain the best surgical result in ptosis, it is necessary to select the appropriate operation for each case according to levator function, degree of ptosis, its etiology and other factors. For the correction of the congenital ptosis with very poor or absent levator function, frontalis suspension with various many materials and direct transplantation of the frontalis muscle have been used by many authors. Each of the above has its specific virtues and inherent shortcomings. On the basis of comparative study of the conventional techniques and anatomical study of the eyebrow region, we designed a superiorly based frontalis myofascial flap. The orbital portion of the orbicularis oculi muscle was included in the distal end of the frontalis myofascial flap to lengthen the flap. According to our results, this technique of frontalis myofascial flap has several advantages compared to Song's direct frontalis transplantation : (1) the operation can be done under a local anesthesia at the out-patient department with simple procedure and less bleeding. (2) the forehead wrinkles are to not disturbed, (3) this procedure needs only a single incision and does not disturb the important anatomic structures around the eyebrow region.

콘크리트의 급속염화물침투시험에 의한 염화물이온 확산계수 평가에 관한 실험적 연구

김갑수,조봉석,장종호,김재환,김용로,김무한 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(구조계)

Chloride ions are considered to be the major cause of steel corrosion in concrete structures exposed to seashore environments and also permeation of chloride is controlled by chloride diffusion. Therefore, the study on chloride diffusion of concrete have been done so far by many researchers. In this study, several factors such as capacity of voltage, time of an electric current, concentration of NaCl solution, water-cement ratio, and temperature of the solution were examined to grasp what influence they were on the chloride ion diffusion properties using the Rapid Chloride Penetration Test(RCPT) by electrophoresis. Also standing on the basis of the such result application possibility of Rapid Chloride Penetration Test(RCPT) used in this study will be evaluated and the basic data on the durability design for the chloride attack will be suggested.

방사성 인(³²P)이 생쥐 장간막 비만세포에 미치는 영향

이흥식,조사선,윤석봉 최신의학사 1973 最新醫學 Vol.16 No.1

내구성을 고려한 표면피복재의 성능평가에 관한 실험적 연구

김영덕,조봉석,윤종기,김용로,장종호,김무한 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

It is recognized that reinforcement corrosion is the main distress behind the present concern regarding concrete durability. The basic method to prevent reinforcement corrosion is coating the reinforcement concrete with surface coating materials but evaluating their performance is necessary to the work satisfactory because they have different performance for each other. In this study. to evaluate performance of surface coating materials, we compare their properties in terms of sticking strength and permeability of carbonation, chloride ion and water with actual reinforcement corrosion under environment of complex deterioration. The results showed that an increase in age also decreases Carbonation velocity coefficients, increases Chloride ion diffusion coefficients and increases water absorption coefficients. As well, an increase in age also increases corrosion of reinforcement due to permeability of carbonation and chloride ion. And sticking strength of inorganic coating material is higher than organic coating material.

복합열화환경 하에서의 단면복구재의 철근부식특성 평가에 관한 실험적 연구

김영덕,박종호,조봉석,김용로,권영진,김무한 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1

The duties of the restorative material are to bear up against stress and to protect reinforcement corrosion. So the restorative material are estimated by various kinds of strength, permeability and etc. But to evaluate performance of the restorative material accurately, it is necessary to estimate their reinforcement corrosion directly in environment of combined deterioration. In this study, to evaluate performance of restorative materials, we compare their properties in terms of compressive and bending strength and permeability of water and air with actual reinforcement corrosion like ratio of corrosion area, weight reduction and corrosion velocity of steel bar under environment of complex deterioration. The results showed that strength and permeability of restorative materials are similar but their reinforcement corrosions are very different. And there is a case that strength and permeability of restorative material are better than normal concrete but reinforcement corrosions are worse.

국내 발전소별 바텀애시를 잔골재 대체재로 사용한 모르터의 특성에 대한 실험적 연구

송민섭,장재봉,조봉석,김재환,김용로,김무한 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(구조계)

With the advance in industrial development and modern living comfort, the demand for electricity throughout the country is ever increasing. Also the annual consumption of coal by coal-fired power plants is increasing. The amount of ash produced in 2000 is estimated to be about 4.5 million tons. The disposal of this huge amount of ash introduces serious environmental problems. Fly ash among the ash produced is used in building industries as a substitute to cement in concrete and the concrete thus produced is said to be lighter and stronger. But bottom ash among the ash produced is not used because of its poor properties. But encouraging the use of bottom ash as a construction material is a sensible method of utilization as it avoids the problems and costs associated with disposal and provides an alternative aggregate source. This study is aimed at using bottom ash as an alternative fine aggregate source to provide a solution to disposal and insufficient fine aggregate for the production of concrete. So properties of bottom ash produced in power plants were estimated due to the difference of bottom ash produced in each plant. And mortar strength was estimated as basic data to use bottom ash in building industries.