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이채용,김혜라,이정치,김상기,이정길,김종택,Lee, Chai-yong,Kim, Hye-ra,Lee, Jeong-chi,Kim, Sang-ki,Lee, Chung-gil,Kim, Jong-taek 대한수의학회 2003 大韓獸醫學會誌 Vol.43 No.2
Macroscopic investigations were made on the lesions of a total of 101 udders from slaughtered Holstein cows in Gwangju area. Incidence of supernumerary teats was 9.9%. Gross lesions were found in the surface of teats of 29.4% of cows; these lesions comprised papilomatosis (16.0%), fronds (8.9%) and injury at the tip (3.2%). Approximately 95% of the cows had slight to severe teat orifice keratosis. On the mucous membranes of the teat cisterns, fibrosis (22.7%) and congestion (8.9%) were observed. Gross lesions were found in the mammary glands of 68% of cows; these lesions comprised fibrosis (18.8%), serous exudate (4.9%), fatty tissue (4.9%), pus (4.0%), congestion (2.0%).
도태유우(淘汰乳牛)에 있어서의 유방염(乳房炎)에 관(關)한 연구(硏究) 제(第)1보(報) 유방감염(乳房感染)
이채용,강병규,박영준,이정길,Lee, Chai Yong,Kang, Byong Kyu,Park, Yong Jun,Lee, Chung Gil 대한수의학회 1980 大韓獸醫學會誌 Vol.20 No.2
The udders of 28 culled dairy cows were removed at slaughter and bacteria isolated. Isolations of major known mammary pathogens comparised Staphylococcus sp. (40.7%), non-identified Gram's negative rods (33.2%) and E. coli (7.4%). In the mixed infection, Staphylococcus sp. was most frequently involved. Drug sensitivity tests were performed on several bacterial species by disc method. These tests indicated that the microorganisms isolated from clinical mastitis of dairy cows were more resistant to antimicrobial agents than the organisrms isolated from milk samples.
기니픽에 있어서 실험적(實驗的) 앨러지성(性) 접촉성(接觸性) 피부염(皮膚炎)
이채용,이정길,이주묵,Lee, Chai-yong,Lee, Chung-gil,Lee, Ju-mook 대한수의학회 1984 大韓獸醫學會誌 Vol.24 No.2
An expeliment was carried out to measure the cellular immune response in guinea pigs by sensitizing the animals with 2, 4-dinitrochlorobenzene(DNCB). The guinea pigs could be sensitized with one application of DNCB. The sensitizing and challenge dose was standardized. The histological response was characteristic of a delayed hypersensitivity reaction.
2, 4-Dinitrochlorobenzene으로 유발(誘發)된 오리와 닭의 지연형(遲延型) 피부과민증(皮膚過敏症)
이채용,이정길,이주묵,Lee, Chai-yong,Lee, Chung-gil,Lee, Joo-muk 대한수의학회 1986 大韓獸醫學會誌 Vol.26 No.1
An experiment was carried out to measure the cellular immune response in the animals by sensitizing the animals with 2, 4-dinitrochlorobenzene(DNCB). The fowls could be sensitized with primary application of DNCB. The sensitizing and challenge dose was standardized. Heterophils were prominent in the early inflammatory response in the superficial and deep dermal regions with scattering of eosinophils. The histological response in the fowls was characteristic of a delayed hypersensitivity reaction.
진돗개에서 ivermectin의 독성 I. 임상증상과 혈액학적 변화 관찰
이채용,오석일,이정길,Lee, Chai-yong,Oh, Seok-il,Lee, Chung-gil 대한수의학회 1997 大韓獸醫學會誌 Vol.37 No.4
Ivermectin is a synthetic derivative of the naturally occurring avermectin $B_{1a}$ (22, 23-dihydroavermectin $B_{1a}$) and $B_{1b}$ (22, 23-dihydroavermectin $B_{1b}$), It is widely used as antiparasitic and pesticidal agents because of its remarkably potent and broad spectrum of antiparasitic activity. Although the drug has shown excellent anthelmintic effects, development of toxicosis in some animals such as the Collie species of dog is well documented. However, no studies have been reported on the toxic effects of the drug in Korean native animals such as the Jindo dog. The toxic effect of ivermectin was evaluated in 25 Jindo dogs divided into five groups which were orally administered with ivermectin at dosage levels of $200{\mu}g/kg$, $300{\mu}g/kg$, $600{\mu}g/kg$ and $2,500{\mu}g/kg$ of body weight, respectively. Toxic signs were not observed in the groups receiving $200{\mu}g/kg$ and $300{\mu}g/kg$ B.W. ivermectin. One dog developed mild clinical signs of toxicosis in the group receiving $600{\mu}g/kg$ dosage of ivermectin. In the group with $2,500{\mu}g/kg$ dosage, all dogs developed mild (salivation, drooling, vomiting, mydriasis, and/or confusion) and/or moderate (ataxia and tremors) clinical signs of toxicosis. Hematologic changes were not observed in the groups receiving $200{\mu}g/kg$, $300{\mu}g/kg$ and $600{\mu}g/kg$ B.W. ivermectin. In the groups receiving $2,500{\mu}g/kg$ B.W., total erythrocyte counts, total and differential leukocyte counts and hemoglobin levels were not affected by drug. Aspartate aminotransferase levels were increased after administration of ivermectin, while serum cholesterol and blood glucose levels were decreased.
견모낭충증(犬毛囊蟲症)의 동거감염(同居感染)에 관한 연구(硏究)(I)
이채용,이정길,서계원,Lee, Chai-yong,lee, Chung-gil,Seo, Gyeo-won 대한수의학회 1992 大韓獸醫學會誌 Vol.32 No.3
In order to obtain basic data concerning the treatment of canine demodicosis, 8 Doberman Pinschers were infected with Demodex canis. The clinical signs, were examined after infection, and their hematological and blood chemical values were determined, along with four non-infected control dogs of same breed. The number of white blood cells, especially the number of band neutrophils was significantly higher(p<0.01) in the infected than in the non-infected control dogs. This result indicated that the first episode of secondary infection should be treated with an appropriate antibiotics based on the culture and sensitivity test. The red blood cell counts, packed cell volume, hemoglobin contents, and serum albumin levels were significantly lower (p<0.01~0.001) in the infected than in the non-infected control dogs. These results suggested that the infected dogs had an anemia due to malnutrition. Thus, the infected dogs should be on a well balanced, high protein diet.
광주(光州)·전남지역내(全南地域內) 소의 바이러스성 질병(疾病)에 관한 혈청학적(血淸學的) 연구(硏究)
이채용,이정길,남선문,Lee, Chai-yong,Lee, Chung-gil,Nam, Sun-moon 대한수의학회 1995 大韓獸醫學會誌 Vol.35 No.3
Sera from 304 Holsteins or Korean native cattle were collected from slaughterhouse in Kwangju area to study the infection of major virus-borne diseases. Serum antibody titers against infectious bovine rhinotracheitis virus(IBRV), bovine viral diarrhea virus(BVDV), parainfluenza type-3 virus(PI-3V), bovine ephemeral fever virus(BEFV), bovine Ibaraki virus(BIV), bovine Akabane virus(BAKV), bovine rotavirus(BRV), bovine coronavirus(BCV) were measured by serum neutralization tests. Results which obtained were as follows. Sera from 280 cattle(92.1%) contained antibodies against BRV which rate was the highest among the 8 viruses, and serum antibodies against BCV, BVDV, BIV, BAKV, BEFV, IBRV and PI-3V were detected from 266(87.5%), 149(49%), 108(35.5%), 94(30.9%), 80(26.3%), 32(10.5%) and 24(7.9%) cattle, respectively. Prevalence of seropositives to BVDV, BIV, BAKV, BEFV were higher among Holsteins than among the Korean native cattle(P<0.05). Prevalence of antibody titers against BVDV, BIV and BEFV in Korean native cattle were higher among females than males, while more males contained antibodies to BAKV, IBRV and PI-3V than females in their blood(P<0.05). Seropositives to BVDV, BIV, BAKV, BEFV and IBRV in Holsteins were higher among females than males(P<0.05). In Korean native cattle, serum antibody titers against IBRV and PI-3V ranged from 1:2~1:32 and 1:2~1:64, respectively, while serum antibody titers against the rest 6 viruses ranged from $1:2{\sim}1:{\geq}256$. In Holsteins, serum antibody titers against IBRV and PI-3V ranged from 1:2~1:64 and 1:2~1:32, respectively, while serum antibody titers against the rest 6 viruses ranged from $1:2{\sim}1:{\geq}256$.
Demodex canis 감염이 화학적으로 유발된 지연형 피부과민증에 미치는 영향
이채용,함현우,이정길,서계원,Lee, Chai-yong,Ham, Hyeon-woo,Lee, Chung-gil,Seo, Kye-won 대한수의학회 1995 大韓獸醫學會誌 Vol.35 No.4
To observe the effect of Demodex canis infection on the cellular immune response and hematological profile, 8 Doberman pinschers experimentally infected with D cains and 4 uninfected control dogs were sensitized with 2, 4-dinitro-chlorobenzene(DNCB) on the skin and were challenged with DNCB 14 days after the initial sensitization to elicit allergic contact dermatitis. Histological and hematological changes of these dogs were then observed. Macroscopic changes of skin challenged with DNCB in D canis-infected dogs included significantly reduced area of allergic reaction(p<0.05) than in uninfected control group. Infiltration of inflammatory cells in the D canis-infected group was also significantly reduced(p<0.05) than in the uninfected control group. These changes indicated that the cell-mediated immune response of the animals was suppressed by the infection with D canis. Total white blood cell count in dogs infected with D canis was increased when dogs were sensitized with DNCB (p<0.01). The result appeared to be caused by stress due to D canis infection, secondary bacterial infection and decreased efficacy of general body defense system. Blood eosionophils were increased in D canis-infected dogs which appreared to be caused by the allergic contact dermatitis. Blood chemistry analysis revealed that total protein and globulin were increased(p<0.05), while albumin level was decreased. This result appeared to be caused by secondary bacterial infection.
Mycobacterium bovis 감염(感染)이 화학적(化學的)으로 유발(誘發)된 지연형(遲延型) 피부과민증(皮膚過敏症)에 미치는 영향(影響)
이채용,이정길,박영준,Lee, Chai-yong,Lee, Chung-gil,Park, Young-jun 대한수의학회 1986 大韓獸醫學會誌 Vol.26 No.2
In order to evaluate the effects of the cell-mediated immunity of the animal in the chronic diseases the guinea pigs and rabbits were inoculated with Mycobacterium bovis. After 6 weeks these animals were sensitized and challenged with 2,4-dinitrochlorobenzene. The cutaneous reactions observed in these animal species were similar each other. Macroscopic and microscopic responses in the animal experimentally infected with M. bovis were markedly reduced compared to those in the control animals. The results indicated that the cell-mediated immunity of the animals was depressed by infection of M. bovis.
Chai Yong LEE(李採瑢),Young Jun PARK(朴永埈),Chung Gil LEE(李政吉),Byung Seung NA(羅炳勝) 한국예방수의학회 1990 예방수의학회지 Vol.14 No.3
Infestation with Sarcoptes scabiei var. suis of 516 fatteners of 2~3 months old selected randomly from 3 intensive swine farms in Chonnam area were investigated from May, 1989 to August, 1990. In addition, blood chemical values and histopathological changes were also examined from the pigs which had been confirmed to be infected with Sarcoptes scabiei var. suis. The results obtained are summarized as follows ; 1. It was observed that 141(27.32%) out of 516 pigs observed were infested with Sarcoptes scabiei var. suis. Prevalence of the infestation in 3 intensive farms was 32.95% in Yongkwang, 24.44% in Suncheon and 24.38% in Muan, respectively. 2. Seasonal prevalence was found to be significantly (p〈0.05) higher in spring and winter than in summer and autumn. 3. Blood chemical values revealed that blood glucose level was significantly (p〈0.01) higher in pigs infected with Sarcoptes scabiei var. suis than in noninfected pjgs. On the contrary, blood area nitrogen(BUN) cholesterol level were lower in infected pigs than in noninfected pigs. 4. Major histopathological findings of the skin lesions of the infected pigs were acanthosis, spongiosis in epidermis and infiltration of inflammatory cells and edema in dermis.