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Castro-Perez, B.I.,Garzon-Proano, J.S.,Lopez-Soto, M.A.,Barreras, A.,Gonzalez, V.M.,Plascencia, Alejandro,Estrada-Angulo, A.,Davila-Ramos, H.,Rios-Rincon, F.G.,Zinn, R.A. Asian Australasian Association of Animal Productio 2013 Animal Bioscience Vol.26 No.8
Four male lambs (Katahdin; average live weight $25.9{\pm}2.9$ kg) with "T" type cannulas in the rumen and proximal duodenum were used in a $4{\times}4$ Latin square experiment to evaluate the influence of supplemental dry distillers grain with solubles (DDGS) levels (0, 10, 20 and 30%, dry matter basis) in substitution for dry-rolled (DR) corn on characteristics of digestive function and digestible energy (DE) of diet. Treatments did not influence ruminal pH. Substitution of DR corn with DDGS increased ruminal neutral detergent fiber (NDF) digestion (quadratic effect, p<0.01), but decreased ruminal organic matter (OM) digestion (linear effect, p<0.01). Replacing corn with DDGS increased (linear, $p{\leq}0.02$) duodenal flow of lipids, NDF and feed N. But there were no treatment effects on flow to the small intestine of microbial nitrogen (MN) or microbial N efficiency. The estimated UIP value of DDGS was 44%. Postruminal digestion of OM, starch, lipids and nitrogen (N) were not affected by treatments. Total tract digestion of N increased (linear, p = 0.04) as the DDGS level increased, but DDGS substitution tended to decrease total tract digestion of OM (p = 0.06) and digestion of gross energy (p = 0.08). However, it did not affect the dietary digestible energy (DE, MJ/kg), reflecting the greater gross energy content of DDGS versus DR corn in the replacements. The comparative DE value of DDGS may be considered similar to the DE value of the DR corn it replaced up to 30% in the finishing diets fed to lambs.
Castro-Perez, Beatriz I.,Estrada-Angulo, Alfredo,Rios-Rincon, Francisco G.,Nunez-Benitez, Victor H.,Rivera-Mendez, Carlos R.,Urias-Estrada, Jesus D.,Zinn, Richard A.,Barreras, Alberto,Plascencia, Alej Asian Australasian Association of Animal Productio 2020 Animal Bioscience Vol.33 No.6
Objective: The objective of this experiment was to evaluate the effect of shade allocation and shade plus fan on growth performance, dietary energy utilization and carcass characteristics of feedlot cattle under tropical ambient conditions Methods: Two trials were conducted, involving a total of 1,560 young bulls (289±22 kg BW) assigned to 24 pens (65 bulls/pen and 6 pens/treatment). Pens were 585 ㎡ with 15 m fence line feed bunks. Shade treatments (㎡ shade/animal) were: i) limited shade (LS) to 1.2 ㎡ shade/animal (LS<sub>1.2</sub>); ii) limited shade to 2.4 ㎡ shade/animal (LS<sub>2.4</sub>); iii) total shade (TS) which correspond to 9 ㎡/animal, and iv) total shade equipped with fans (TS+F). Trials lasted 158 and 183 days. In both studies, the average weekly maximum temperature exceeded 34℃. Results: Increasing shade allocation tended (p = 0.08) to linearly increases average daily gain (ADG), and dry matter intake (DMI, quadratic effect, p = 0.03). This effect was most apparent between LS<sub>1.2</sub> and LS<sub>2.4</sub>. Shade allocation, per se, did not affect gain efficiency or estimated dietary net energy (NE). Compared with TS, TS+F increased (p<0.05) ADG, gain efficiency, and tended (p = 0.06) to increase dietary NE. There was a quadratic effect of shade on longissimus area and marbling score, with values being lower (p<0.01) for LS<sub>2.4</sub> than for LS<sub>1.2</sub> or TS. Likewise, marbling score was lower for TS+F than for TS. Percentage kidney, pelvic, and heart (KPH) linearly decreased with increasing shade. In contrast, KPH was greater for TS than for TS+F. Conclusion: Providing more than 2.4 ㎡ shade/animal will not further enhance feedlot performance. The use of fans in combination with shade increases ADG and gain efficiency beyond that of shade, alone. These enhancements were not associated with increased DMI, but rather, to an amelioration of ambient temperature humidity index on maintenance energy requirement.
A GENERALIZATION OF MULTIPLICATION MODULES
Perez, Jaime Castro,Montes, Jose Rios,Sanchez, Gustavo Tapia Korean Mathematical Society 2019 대한수학회보 Vol.56 No.1
For $M{\in}R-Mod$, $N{\subseteq}M$ and $L{\in}{\sigma}[M]$ we consider the product $N_ML={\sum}_{f{\in}Hom_R(M,L)}\;f(N)$. A module $N{\in}{\sigma}[M]$ is called an M-multiplication module if for every submodule L of N, there exists a submodule I of M such that $L=I_MN$. We extend some important results given for multiplication modules to M-multiplication modules. As applications we obtain some new results when M is a semiprime Goldie module. In particular we prove that M is a semiprime Goldie module with an essential socle and $N{\in}{\sigma}[M]$ is an M-multiplication module, then N is cyclic, distributive and semisimple module. To prove these results we have had to develop new methods.
A generalization of multiplication modules
Jaime Castro Perez,Jose Rios Montes,Gustavo Tapia Sanchez 대한수학회 2019 대한수학회보 Vol.56 No.1
For $M\in R$-Mod, $N\subseteq M$ and $L\in \sigma \left[ M \right] $ we consider the product $N_{M}L=\sum_{f\in {\rm Hom}_{R} ( M,L ) }f ( N ) $. A module $N\in \sigma \left[ M\right] $ is called an $M$-multiplication module if for every submodule $L$ of $N$, there exists a submodule $I$ of $M$ such that $L=I_{M}N$. We extend some important results given for multiplication modules to $M$-multiplication modules. As applications we obtain some new results when $M$ is a semiprime Goldie module. In particular we prove that $M$ is a semiprime Goldie module with an essential socle and $N$ $\in \sigma \left[ M\right] $ is an $M$ -multiplication module, then $N$ is cyclic, distributive and semisimple module. To prove these results we have had to develop new methods.
Some aspects of Zariski topology for multiplication modules and their attached frames and quantales
Jaime Castro Perez,Jose Rios,Gustavo Tapia Sanchez 대한수학회 2019 대한수학회지 Vol.56 No.5
For a multiplication $R$-module $M$ we consider the Zariski topology in the set $Spec\left( M\right) $ of prime submodules of $M$. We investigate the relationship between the algebraic properties of the submodules of $M$ and the topological properties of some subspaces of $Spec\left( M\right) $. We also consider some topological aspects of certain frames. We prove that if $ R $ is a commutative ring and $M$ is a multiplication $R$-module, then the lattice $Semp\left( M/N\right) $ of semiprime submodules of $M/N$ is a spatial frame for every submodule $N$ of $M$. When $M$ is a quasi projective module, we obtain that the interval $\mathcal{\uparrow } (N)^{Semp\left( M\right) }=\left\{ P\in Semp\left( M\right) \mid N\subseteq P\right\} $ and the lattice $Semp\left( M/N\right) $ are isomorphic as frames. Finally, we obtain results about quantales and the classical Krull dimension of $M$.
Estrada-Angulo, A.,Aguilar-Hernandez, A.,Osuna-Perez, M.,Nunez-Benitez, V.H.,Castro-Perez, B.I.,Silva-Hidalgo, G.,Contreras-Perez, G.,Barreras, A.,Plascencia, A.,Zinn, R.A. Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.5
Twenty $Pelibuey{\times}Katahdin$ ewes ($35{\pm}2.3kg$) were used to determine the effects of the consumption of standardized plant extract containing a mixture of quaternary benzophenanthridine alkaloids and protopine alkaloids (QBA+PA) on growth performance, dietary energetics, visceral mass, and ruminal epithelial health in heat-stressed ewes fed with a high-energy corn-based diet. The basal diet (13.9% crude protein and 2.09 Mcal of net energy [NE] of maintenance/kg of dry matter) contained 49.7% starch and 15.3% neutral detergent fiber. Source of QBA+PA was Sangrovit RS (SANG) which contains 3 g of quaternary benzophenathridine and protopine alkaloids per kg of product. Treatments consisted of a daily consumption of 0 or 0.5 g SANG/ewe. Ewes were grouped by weight and assigned to 10 pens (5 pens/treatment), with two ewes per pen. The experimental period lasted 70 days. The mean temperature humidity index during the course of this experiment was $81.7{\pm}1.0$ (severe heat stress). There were no treatment effects on water intake. Dry matter intake was not affected (p = 0.70) by treatments, but the group fed SANG had a numerically (11.2%) higher gain in comparison to the control group, SANG improved gain efficiency (8.3%, p = 0.04), dietary NE (5.2%, p<0.01) and the observed-to-expected NE (5.9%, p<0.01). Supplemental SANG did not affect ($p{\geq}0.12$) carcass characteristics, chemical composition of shoulder, and organ weights (g/kg empty body weight) of stomach complex, intestines, and heart/lung. Supplemental SANG decreased liver weight (10.3%, p = 0.02) and increased visceral fat (16.9%, p = 0.02). Rumen epithelium of ewes fed SANG had lower scores for cellular dropsical degeneration (2.08 vs 2.34, p = 0.02), parakeratosis (1.30 vs 1.82, p = 0.03) and neutrophil infiltration (2.08 vs 2.86, p = 0.05) than controls. It is concluded that SANG supplementation helped ameliorate the negative effects of severe heat on growth performance of feedlot ewes fed high-energy corn-based diets. Improvement in energetic efficiency may have been mediated, in part, by anti-inflammatory effects of supplemental SANG and corresponding enhancement of nutrient uptake.
Veronica, Castro-Aceituno,Siddiqi, Muhammad Hanif,Ahn, Sungeun,Sathishkumar, Natarajan,Noh, Hae Yong,Simu, Shakina Yesmin,Jimenez Perez, Zuly E.,Yang, Deok Chun Current Science Association 2016 Current science Vol.111 No.6
<P>In previous studies compound K (CK), an active metabolite ginsenoside from Panax ginseng, was shown to exhibit anti-cancer activity. However, the mechanism of CK through the EGFR/H-Ras pathway in cancer cells has not been reported so far. Therefore, we focused on the effect of CK as an EGFR and H-Ras inhibitor by in silico and in vitro studies using A549 cells. The biological activity prediction shows that CK exhibits chemopreventive, anticarcinogenic and anti-metastatic activity. Also, using molecular docking studies it has been shown that CK exhibits a strong binding energy with EGFR and H-Ras than Erlotinib. CK inhibits cell viability, decreases cell migration, induces apoptosis and strongly decreases gene expression of EGFR and H-Ras genes in vitro. This finding suggests that the EGFR pathway is involved in the anti-cancer activity of CK of EGF-enhanced A549 lung cancer cell line.</P>
Paola Perez,Jaime Patiño,Alexis A. Franco,Fernando Rosso,Estefania Beltran,Eliana Manzi,Andrés Castro,Mayra Estacio,Diego Medina Valencia 대한혈액학회 2022 Blood Research Vol.57 No.1
Background Antifungal prophylaxis is recommended for hematopoietic stem cell transplantation (HSCT) to decrease the incidence of invasive fungal infections (IFI). This study aimed to compare the two groups of antifungal prophylaxis in pediatric patients undergoing allogeneic HSCT. Methods This observational, analytic, retrospective cohort study compared the incidence of IFI with antifungal prophylaxis with voriconazole vs. other antifungals in the first 100 days after allogeneic HSCT in patients aged <18 years between 2012 and 2018. The statistical analysis included univariate and multivariate analyses and determination of the cumulative incidence of invasive fungal infection by the Kaplan‒Meier method using STATA 14 statistical software. Results A total of 139 allogeneic HSCT were performed. The principal diagnosis was acute leukemia (63%). The 75% had haploidentical donors, and 50% used an antifungal in the month before transplantation. Voriconazole (69%) was the most frequently administered antifungal prophylaxis. The cumulative incidence of IFI was 5% (7 cases). Of the patients with IFIs, four began prophylaxis with voriconazole, one with caspofungin, and one with fluconazole. Additionally, six were possible cases, one was proven (Candida parapsilosis), and 1/7 died. Conclusion There were no differences in the incidence of IFI between patients who received prophylaxis with voriconazole and other antifungal agents.