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YOO, SUNGYUL,GHAFOOR, KASHIF,KIM, JEONG UN,KIM, SANGHUN,JUNG, BORA,LEE, DONG-UN,PARK, JIYONG ational Association for Food Protection 2015 Journal of food protection Vol.78 No.6
<P>Nonpasteurized orange juice is manufactured by squeezing juice from fruit without peel removal. Fruit surfaces may carry pathogenic microorganisms that can contaminate squeezed juice. Titanium dioxide-UVC photocatalysis (TUVP), a nonthermal technique capable of microbial inactivation via generation of hydroxyl radicals, was used to decontaminate orange surfaces. Levels of spot-inoculated Escherichia coli O157:H7 (initial level of 7.0 log CFU/cm2) on oranges (12 cm2) were reduced by 4.3 log CFU/ml when treated with TUVP (17.2 mW/cm2). Reductions of 1.5, 3.9, and 3.6 log CFU/ml were achieved using tap water, chlorine (200 ppm), and UVC alone (23.7 mW/cm2), respectively. E. coli O157:H7 in juice from TUVP (17.2 mW/cm2)-treated oranges was reduced by 1.7 log CFU/ml. After orange juice was treated with high hydrostatic pressure (HHP) at 400 MPa for 1 min without any prior fruit surface disinfection, the level of E. coli O157:H7 was reduced by 2.4 log CFU/ml. However, the E. coli O157:H7 level in juice was reduced by 4.7 log CFU/ml (to lower than the detection limit) when TUVP treatment of oranges was followed by HHP treatment of juice, indicating a synergistic inactivation effect. The inactivation kinetics of E. coli O157:H7 on orange surfaces followed a biphasic model. HHP treatment did not affect the pH, °Brix, or color of juice. However, the ascorbic acid concentration and pectinmethylesterase activity were reduced by 35.1 and 34.7%, respectively.</P>
Yoo, In Kyung,Jeen, Yoon Tae,Kang, Seung Hun,Lee, Jae Hyung,Kim, Seung Han,Lee, Jae Min,Choi, Hyuk Soon,Kim, Eun Sun,Keum, Bora,Chun, Hoon Jai,Lee, Hong Sik,Kim, Chang Duck,Ladas., Spiros Wolters Kluwer Health 2016 Medicine Vol.95 No.28
<P><B>Abstract</B></P><P><B>Background and Aim:</B></P><P>Low-volume polyethylene glycol with ascorbic acid (PEG-Asc) use is reported to be as safe and effective as traditional 4-L polyethylene glycol use. However, PEG-Asc produces bubbles, which cause problems during colonoscopy. Data on the effects of using antifoaming agents such as simethicone with PEG-Asc are lacking. The aim of this CONSORT-prospective, randomized, observer-blinded, controlled trial is to compare the quality of bowel preparation and compliance between PEG-Asc users and PEG-Asc plus simethicone users.</P><P><B>Methods:</B></P><P>Adult outpatients aged 18 to 80 years undergoing colonoscopy were recruited to the study. Two hundred sixty patients were randomly assigned to 1 of 2 treatment arms, PEG-Asc or PEG-Asc plus simethicone. The primary outcome measure was the bowel cleansing quality using Boston bowel preparation scale and bubble scores. The secondary outcome measures were patient tolerability and doctor tolerability.</P><P><B>Results:</B></P><P>The simethicone group showed superior cleansing results (6–9 Boston scale scores: 99% vs. 84%, <5% bubble scores: 96% vs. 49%, <I>P</I> < 0.001) and fewer gastrointestinal symptoms (abdominal fullness: 24% vs. 55%, colicky pain: 5% vs. 24%, <I>P</I> < 0.001) than the non-simethicone group. Moreover, endoscopist fatigue during colonoscopy was lower in the simethicone group than in the non-simethicone group (1.31 ± 0.75 vs. 2.97 ± 2.14, <I>P</I> < 0.001).</P><P><B>Conclusion:</B></P><P>PEG-Asc plus simethicone use was more effective and associated with better patient and endoscopist tolerance than PEG-Asc use. Therefore, this combination is recommended as one of the promising methods for bowel preparation before colonoscopy.</P>
학업성취에 따른 학습자 특성 분석연구 : A대학 사례를 중심으로
유은하(Yoo Eunha),이명화(Lee Myunghwa),오보라(Oh Bora) 학습자중심교과교육학회 2020 학습자중심교과교육연구 Vol.20 No.22
본 연구는 대학 맥락에서 학습성취에 따른 학습자 특성을 파악하여 맞춤형 학습지원 체계를 마련하고 학업중도탈락 예방을 위한 기초자료를 제공하는데 목적이 있다. 이를 위하여 A대학 재학생 569명이 본 연구에 참여하였으며, 연구 결과는 다음과 같다. 첫째, 학업성취도에 따라 학습역량(고차원 학습, 반성적·통합적 학습, 학습전략, 능동적·협동적 학습)과 대학생활 관련 요인(교수-학생 상호작용, 효과적 교수, 교우 관계, 교직원 관계, 지원적 대학환경)이 유의하게 향상되는 것을 확인하였다. 둘째, 학업성취를 예측하는 요인을 살펴본 결과, 학습전략 요인이 학업성취를 유의하게 예측하는 것으로 나타났다. 이와 같은 연구결과를 토대로 본 연구에서는 학습자의 성취 및 대학생활적응 수준에 따른 학습지원체계를 제안하였으며, 이를 통해 학습자의 학업중도탈락을 예방하고 학습역량 향상을 위한 맞춤화된 지원을 위한 기초자료를 제시하였다는 점에서 의의가 있다. The purpose of this study was to provide the basic data for systematical learning support that would be reducing the rate of dropout. The 569 of cases were used to analyze for this study, and the key findings were as follows: First, the higher the academic achievement, the higher the learning competencies and academic adaptation. Second, as a result of investigating the predicting factor on learning achievement, students learning strategy have a significantly predicted on learning achievement. This research suggested the implications for systematical learning support strategies.
LEE, BORA,LEE, DAE YOUNG,YOO, KI HYUN,BAEK, NAM IN,PARK, JONG-HWA,CHUNG, IN SIK Spandidos Publications 2012 Oncology letters Vol.4 No.1
<P>The aim of the present study was to investigate the cytotoxic effect of calenduloside E 6'-methyl ester (oleanolic acid 3-O-β-D-glucuronopyranoside-6'-methyl ester) isolated from Acanthopanax sessiliflorus fruits was investigated in CT-26 mouse colon carcinoma cells. Calenduloside E 6'-methyl ester dose-dependently inhibited the viability of CT-26 cells. Apoptosis was characterized by the detection of annexin-V and sub-G1 apoptotic cell populations, terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) and DNA fragmentation experiments. Results showed that the number of immunostained annexin-V-FITC and sub-G1 cells increased after treatment with calenduloside E 6'-methyl ester. Calenduloside E 6'-methyl ester also increased terminal deoxynucleotidyl transferase dUTP nick end labeled-CT-26 cells. It induced DNA fragmentation. and the cleavage of caspase-8, -9, -3 and poly ADP-ribose polymerases. In addition, calenduloside E 6'-methyl ester suppressed the volume and weight of tumors in BALB/c mice subcutaneously implanted with CT-26 cells. These results indicate that calenduloside E 6'-methyl ester induces apoptosis in CT-26 mouse colon carcinoma cells and inhibits tumor growth in a CT-26 carcinoma animal model.</P>
Nam Bora,Sung Yoon-Kyoung,Choi Chan-Bum,Kim Tae-Hwan,Jun Jae-Bum,Bae Sang-Cheol,Yoo Dae-Hyun,Cho Soo-Kyung 대한의학회 2021 Journal of Korean medical science Vol.36 No.41
Background: To evaluate the incidence of fractures and fracture risk factors in Korean patients with polymyalgia rheumatica (PMR). Methods: All PMR patients who visited a rheumatology clinic at a tertiary referral hospital between March 2005 and March 2018 were retrospectively assessed. We estimated bone mineral density (BMD) screening rate within 6 months of the first visit and classified the patients according to the performance and results of BMD screening. Incidence rates (IRs) of fractures were calculated in each group and risk factors for fractures were identified using Poisson regression analysis. Results: A total of 95 PMR patients with median (interquartile range) age of 64.0 (56.0–72.0) years were included. Baseline BMD was assessed in only 55.8% of these patients (n = 53); 24 patients with osteoporosis, 20 with osteopenia, and 9 with normal BMD. During 433.1 person-years (PYs) of observation, 17 fractures occurred in 12 patients (IR, 3.93 [95% confidence interval (CI), 2.46–6.26]/100 PYs); 8.32 (95% CI, 4.09–16.90)/100 PYs in the osteopenia group, 3.40 (95% CI, 1.30–8.90)/100 PYs in the osteoporosis group, and 3.37 (95% CI, 1.53–7.39)/100 PYs in the no BMD test group. Risk factors for fractures were female sex, advanced age (≥ 65 years), longer follow-up duration, initial glucocorticoid dose ≥ 10 mg/day, and higher cumulative glucocorticoid dose over the first 6 months. Conclusion: The incidence rate of fractures in Korean patients with PMR was 3.93/100 PYs. Female sex, advanced age, longer follow-up duration, and increased glucocorticoid dose are risk factors for osteoporotic fracture.
유영재(Yoo, YoungJae),장석헌(Chang, Sukhun),박보라(Park, Bora) 한국범죄심리학회 2010 한국범죄심리연구 Vol.6 No.1
사회가 복잡해지고 다원화되면서 우리나라에서도 인질사건은 앞으로 점차 증가할 것으로 예상되고 있다 인질협상은 인질사건 해결에 있어 중요한 역할을 담당하고 있다. 따라서 효과적인 인질협상은 평화적인 인질사건 해결을 위한 가장 유용한 수단이기도 하다. 과거 인질사건이 발생한 경우 테러진압특수부대에 의한 무력진압이 주된 대응수단이 되어 왔으나 최근에는 인질협상을 통하여 인질의 사상을 비롯한 각종 피해를 최소화하는 것이 보다 합리적이라고 여겨지고 있다. 실제로 지난 30 여 년 동안 인질협상 분야는 경찰을 포함한 법집행 부문에서 투자비용 대비 효과가 가장 높은 분야 중 하나로 여겨지고 있다 특히 경찰이 다루는 인질사건의 대부분이 테러조직에 의해 계획된 사건이라기보다, 우발적인 인질사건이라는 점에 주목하여 효과적인 인질협상기법에 대한 논의가 필요하다. 이 논문에서는 인질사건이 발생할 경우, 경찰이 사용할 수 있는 효과적인 협상기법을 살펴보았다. 이를 위하여 인질사건의 유형을 살펴보고, 인질협상의 필요성 및 목표를 알아보았다. 그리고 인질상황의 심리를 살펴본 후 이를 바탕으로 효과적인 협상기법에 대하여 기본적인 사항을 중심으로 다루었다. As the society gets more complicated and more diversified, it is expected that hostage situations would be getting increased more. When hostage situation happens, hostage negotiation plays an important role in its resolution process. Thus, hostage negotiation is the most successful tool to solve the hostage situations peacefully. When hostage situations happened, suppression by SWAT team was mainly used in the past, however, it is considered more reasonable to use hostage negotiations. During the last three decades, hostage negotiations has demonstrated its value in law enforcement agencies Especially, most of hostage situations that the police handle are spontaneous rather than deliberate. Focusing on this characteristic, therefore, it is needed to explore an effective negotiation skills. This study explores the negotiation skills which the police can utilize in the hostage situations. To do this, the typology of hostage situations was argued, and then, the necessity and purpose of hostage negotiation were illustrated. Also the psychology of hostage situations was explored and, based on this theoretical background, effective negotiation skills were illustrated