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Knowledge management for effective research collaboration activities within Universities in Zimbabwe
( Kudzanai Charlton Chiy Anike ) 한국정책학회 2015 한국정책학회 동계학술발표논문집 Vol.2015 No.-
Science and technology universities in Zimbabwe need to be cognizant of the impact of Knowledge management for them to be recognized as highly innovative institutions internationally. This research explored the impact of knowledge management enablers (i.e. knowledge self-efficacy, top management support, organizational culture, organizational rewards, Knowledge, knowledge management system Quality, openness in communication reciprocal benefits and trust) on knowledge sharing and the resultant effects on research collaboration by Science and Technology University lecturers. This research will assist Administrators in policy making decision on enhancing knowledge management to encourage lecturers to conduct research collaboration in Science and Technology. The reviewed literature show that knowledge management factors stimulate knowledge sharing which in turu positively influences research collaboration
Okpoko, Ephraim,Egboka, Boniface,Anike, Luke,Okoro, Elizabeth Korean Society of Environmental Engineers 2013 Environmental Engineering Research Vol.17 No.1
Alternative sources of water are sought in some water stressed communities in the study area. The study focuses on the Aguata-Awka area of southeastern Nigeria. Aquifers occur at great depths, and surface waters may be far from homesteads. The scarcity of water has necessitated the people to adopt various local technologies for harvesting rainfall. The local technology includes collecting rainwater from roofs and channeling the water into large underground tanks, shallow wells and surface reservoirs. Large concrete tanks of $6m{\times}6m{\times}4m$ dimensions are often built underground and can store $144m^3$ of water. Surface reservoirs built on 4 m concrete pillar supports having dimensions of $10m{\times}10m{\times}4m$ and have a storage capacity of $400m^3$. Water samples were collected at 3 different locations of Agulu, Ekwulobia, and Awka and were analyzed for their physical, chemical, and bacteriological parameters. Results indicate a range of values for pH, 5.9 to 7.1; turbidity, 0.9 to 2.7; total dissolved solids, 80 to 170 mg/L; total hardness, 4.5 to 6.4 mg/L; magnesium, 1.2 to 1.4 mg/L; bicarbonate, 19.4 to 83.6 mg/L; and sulfate, 3.6 to 6.4 mg/L. Bacteriological analysis results were negative for fecal and total coliform counts. All parameters, with the exception of pH where aluminum and galvanized iron roofs are used for collection, fall within the recommended guidelines for drinking water quality of the World Health Organization, and the Standard Organization of Nigeria, new Nigerian standards for drinking water quality. Magnesium is above the maximum permitted level for consumer acceptability of the Nigerian standards for drinking water quality. The water can be classified as fresh moderately hard and soft. The water can be described as a calcium and bicarbonate type.
Ephraim Okpoko,Boniface Egboka,Luke Anike,Elizabeth Okoro 대한환경공학회 2013 Environmental Engineering Research Vol.18 No.2
Alternative sources of water are sought in some water stressed communities in the study area. The study focuses on the Aguata-Awka area of southeastern Nigeria. Aquifers occur at great depths, and surface waters may be far from homesteads. The scarcity of water has necessitated the people to adopt various local technologies for harvesting rainfall. The local technology includes collecting rainwater from roofs and channeling the water into large underground tanks, shallow wells and surface reservoirs. Large concrete tanks of 6 m × 6 m × 4 m dimensions are often built underground and can store 144 m3 of water. Surface reservoirs built on 4 m concrete pillar supports having dimensions of 10 m × 10 m × 4 m and have a storage capacity of 400 m3. Water samples were collected at 3 different locations of Agulu, Ekwulobia, and Awka and were analyzed for their physical, chemical, and bacteriological parameters. Results indicate a range of values for pH, 5.9 to 7.1; turbidity, 0.9 to 2.7; total dissolved solids, 80 to 170 mg/L; total hardness, 4.5 to 6.4 mg/L; magnesium, 1.2 to 1.4 mg/L; bicarbonate, 19.4 to 83.6 mg/L; and sulfate, 3.6 to 6.4 mg/L. Bacteriological analysis results were negative for fecal and total coliform counts. All parameters, with the exception of pH where aluminum and galvanized iron roofs are used for collection, fall within the recommended guidelines for drinking water quality of the World Health Organization, and the Standard Organization of Nigeria, new Nigerian standards for drinking water quality. Magnesium is above the maximum permitted level for consumer acceptability of the Nigerian standards for drinking water quality. The water can be classified as fresh moderately hard and soft. The water can be described as a calcium and bicarbonate type.
Reclassification of Five BRCA1/2 Variants with Unknown Significance Using Complex Functional Study
Anikó Bozsik,János Papp,Vince Kornél Grolmusz,Attila Patócs,Edit Oláh,Henriett Butz 대한암학회 2022 Cancer Research and Treatment Vol.54 No.4
Purpose While BRCA1/2 genes are commonly investigated, variants of unknown significance (VUS) and variants with potential splice effect are still being detected and they represent a substantial challenge in genetic counseling and therapy. Materials and Methods Out of genetically tested 3,568 hereditary breast and ovarian cancer probands five, functionally not investigated variants with potential splice-modifying effect were subjected to functional characterization. Transcript-level analysis on peripheral blood-derived RNA of the carriers was performed to test aberrant splicing. The completeness of the aberrant splicing event was also studied, existence and extent of nonsense-mediated decay was even addressed. Clinical and phenotype data, pedigree and co-segregation analyses were also done. Locus-specific loss of heterozygosity (LOH) in tumor tissues was additionally tested. Results In case of the BRCA1:c.4484+4dupA and the BRCA1:c.5407-10G>A variants functional results allowed us to reclassify them from VUS into likely pathogenic category. BRCA1:c.4358-31A>C, by producing incomplete aberrant splicing, was highlighted as strong VUS, but in lack of other supporting evidence, re-categorization was not possible. The likely pathogenic assertion of previously not reported BRCA2:c.8487G>T was reinforced based on its spliceogenic property and tumor LOH, while BRCA2:c.793G>A failed to present aberrant splicing in spite of suggestive predictions, which altered its original VUS evaluation into likely benign class. Conclusion We presented molecular and clinical evidence for reclassification of four out of five BRCA1/2 variants. Both up- and down-classification harbour important clinical significance. Patients carrying re-classified pathogenic variants in the future will not be dropped out from medical surveillance, preventive measures, treatment and predictive family screening in relatives at risk.
Application of Forest Optimization Algorithm for the Resource Constraint Project Scheduling
Anik Yuesti,Rizqy Amalia Putri,Hussein Tuama Hazim,Oleg N. Polukhin,Hendrixon,Israr AHMAD,Tzu-Chia Chen,Vo Hoang Ca,Huynh Tan Hoi,Surendar Aravindhan 대한산업공학회 2022 Industrial Engineeering & Management Systems Vol.21 No.2
Project scheduling is one of the most complex yet important issues in project-based planning. Scheduling is a topic that has entered the project from the production space and has been considered by many researchers in recent years. This problem has always faced many challenges due to its complex limitations in the real world. One of these issues is resource scheduling, known in optimization as the RCPSP problem. The study's main aim is to investigate the applica-tion of a forest optimization algorithm for resource constraint project scheduling. In this research, the RCPSP problem is optimized. A mathematical model is then proposed and then optimized using meteorological algorithms for forest optimization and refrigeration simulation. A hybrid meta-algorithm has also been developed for this document. Examination and comparisons of this algorithm show that the proposed method has the necessary efficiency both in terms of speed and quality of solutions.
A Decision Making Method for Reconfiguration of Adaptive Info-communications Systems
Anik Yuesti,Saule Gabitovna Serikbayeva,Vasilya Minsalichovna Gafurova,Tatiana Gennadevna Mansurova 대한산업공학회 2021 Industrial Engineeering & Management Systems Vol.20 No.4
The adaptation both information and communication systems to variable external factors is implemented through the modernization activities. In this paper the problem of decision-making for adaptive system reconfiguration under uncertainty is considered. The decision-making method is used to detect a need for reconfiguration, built a set of reconfigurations plans and choose the preferable one based on data collection from diagnostic sensor network. Integral decision-making criterion combines the criterion for selecting a suitable reconfiguration moment and alternative. The main idea of the proposed method is to combine the multifactor active diagnostic model, weighted utility and preference theory, decision-making technique under uncertainty with comparison methods for fuzzy trees with incomplete requirement. The general result is achieved by reducing the uncertainty of diagnostic data. It is expected that the proposed decision-making method will help to improve the systems’ suitability in the case of uncertainty.