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Solar urticaria in Korean patients
( Sung Min Kim ),( Young Ah Cho ),( Ji Su Lee ),( Ji Youn Hong ),( Jin Hee Kim ),( Joo Ran Hong ),( Hye In Cheon ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1
Background: Solar urticaria (SU) is an uncommon type of photodermatoses characterized by erythematous wheal with pruritus after sunlight exposure, which shows a female predominance. Only a few studies to analyze the clinical features of SU were reported in Asia. Objectives: We aimed to analyze the clinical and photobiological characteristics of SU in Korea. Methods: We retrospectively investigated the medical records of patients with SU who visited the department of dermatology, Konkuk university medical center from January 2005 to January 2020. Results: Of a total of 44 patients, 36 (81.8%) were male and 8 (18.2%) were female. The mean age at onset was 17.6 years (range, 5-47) and the mean threshold time was 19.7 minutes. Among 32 patients who underwent phototesting, the action spectrum most commonly implicated was ultraviolet (UV) A only in 12 (37.5%), and then visible light (415nm) only was responsible for SU in 8 (25.0%). Three patients (9.4%) were induced by both UVA and visible light (415nm). Even 4 patients (12.5%) were triggered by only natural sunlight. Serum immunoglobulin E levels were measured in 33 patients, and 17 (51.5%) showed values higher than normal. The treatment most widely used were oral antihistamine (43.2%), followed by phototherapy (13.6%). Conclusion: SU is a rare photodermatosis in Korea, which shows a male preponderance. In this study, UVA and visible light (415nm) were predominant action spectrum of SU.
플러그 셀 크기와 품종이 절임용 양파 자구 생산에 미치는 영향
안수란(Ahn Su Ran),임경란(Kyung Ran Im),김도훈(Do Hun Kim),서전규(Jun Kyu Suh) (사)한국생물환경조절학회 2012 시설원예‧식물공장 Vol.21 No.1
절임용 양파자구의 주년생산 공급 및 상품수율 향상의 일환으로 셀 수가 다른 플러그 트레이에 파종하여 가능성을 타진하고자 하여 조생종인 ‘조생썬더볼’ 품종과 중·만생종인 ‘대지’ 품종을 2010년 3월 27일에 105공, 128공 및 162공 플러그 트레이에 파종하여 벤치에서 재배 한 결과는 다음과 같다. 조생종인 조생썬더볼 품종의 엽수는 5월 23일 조사에서 최대를 보인 후 감소하였으나 중·만생종인 대지 품종은 6월 하순에 최대를 보였다. 조생썬더볼 품종의 구 비대는 5월 23일 조사에서 이미 개시되었으나 대지 품종은 6월6일에 개시되었다. 셀 수에 따른 생육은 두 품종 공히 셀 용적이 큰 105공 트레이가 128공 및 162공에 비해 좋은 경향이었다. 셀 수에 따른 구 비대 개시는 차이가 없었으나 구 비대 정도는 셀 수가 많은 것에 비해 적은 것이 큰 경향을 보였다. 자구의 수확시기별 분포는 조생썬더볼 품종은 7월에 모두 수확되었으나 대지 품종은 전체 수확량의 50% 이상이 8월에 수확되었다. 셀 수에 따른 수확시기는 셀 수가 많을수록 늦어졌다. 수확된 자구의 크기별 분포는 두 품종 공히 셀 수가 많을수록 작은 자구의 분포가 많았다. This study was conducted to improve year round production of onion sets for pickles and increase their yield by using different cell sizes of plug trays. ‘Josaeng sseondeobol’ and ‘Daeji’ were seeded in 105-cell tray, 128-cell tray, and 162-cell tray on March 27, 2010. ‘Josaeng sseondeobol’ showed the maximum number of leaves on May 23, but ‘Daeji’ showed the maximum in late June. Bulbing of ‘Josaeng sseondeobol’ was already initiated on May 23, but ‘Daeji’ was initiated on June 6. Growth of both varieties was better in 105-cell tray than the others. There wasn’t a difference in bulbing between two varieties by the number of cells, but bulb size was larger in the low number of cells than high ones. ‘Josaeng sseondeobol’ was all harvested in July, but more than 50% of ‘Daeji’ was harvested in August. The result of this study is as follows. Harvest time was delayed as the number of cells is increasing. There was a wide range of small onion sets distribution in both varieties as the number of cells is increasing.
Differential Expressions of Gap Junction Proteins during Differentiation of Rat Neuronal Stem Cells
Se-Ran Yang,Sung-Dae Cho,Nam-Shik Ahn,Ji-Won Jung,Joon-Suk Park,Nguyen Ba Tiep,Ki-Su Park,In-Sun Hong,Eun-Hye Jo,Min-Su Seo,Byong-Su Yoon,Yong-Soon Lee,Kyung-Sun Kang 한국환경성돌연변이발암원학회 2003 한국환경성돌연변이·발암원학회지 Vol.23 No.1
Gap junctional intercellular communication (GJIC) plays a key role during development, process of tissue differentiation, and in maintenance of adult tissue homeostasis. Neural stem cells leading to formation of cell clusters termed “neurospheres”, can differentiate into neurons, oligodendrocytes, and astrocytes. We investigated the expression levels and distribution of connexin43 (Cx43) and connexin32 (Cx32), abundant gap junctional protein in neural cells and in neurospheres isolated from rat fetus embryonic day (ED) 17. During differentiation of neurospheres, expression of Cx43 and 32 were increased time-dependently within 72 h, and then decreased at 7 day in western blot analysis. TPA-induced inhibition<br/> of GJIC was confirmed by decreased fluorescence by SL/DT assay, and induced hyperphosphorylation of Cx43 while no changes in Cx32 levels in western blot assay. Our results indicate that GJIC may be a crucial role in the differentiation of neuronal stem cell. And this GJIC can be inhibited by TPA through the hyperphosphorylation of Cx43.
On-Sook Hur,Sang Gyu Kim,Ho-Cheol Ko,Su Ran Ahn,Jung-Sook Sung,Na-Young Ro,Sukyeung Lee,Yu-mi Choi,Do yoon Hyun,Kyoung-Yul Ryu,Hyung-Jin Baek 한국육종학회 2015 한국육종학회 심포지엄 Vol.2015 No.07
This study aimed to evaluate 105 tomato accessions conserved in National Agrobiodiversity Center regarding their resistance to Ralstonia solanacearum, a soil-borne vascular bacterium that causes lethal wilt diseases of a wide range of crops worldwide. All the accessions are Solanum lycopericum var. lycopersicum including cultivar or breeding lines. At the four leaf stage, the seedlings were inoculated by drenching the soil with the bacterial suspension concentrated of 108 CFU/ml. Plant roots were wounded before inoculation by cutting with the knife. Seven accessions including IT 32899 were rated as resistant, while other 98 accessions were rated as susceptible. IT 32899 scored 0.1 of disease rate and 0.7 of disease index. The selected accessions will be used as a material to reveal the mechanism of wilt tolerance and to identify the host gene involved in defense response.
Uterotrophic and Hershberger Assay for Butyl ρ-Hydroxybenzoic Acid
Ahn, Ji-Yun,Kim, Sung-Ran,Ha, Tae-Youl,Kim, Sung-Su,Han, Chan-Kyu Korean Society of ToxicologyKorea Environmental Mu 2005 Toxicological Research Vol.21 No.2
Butyl $\rho$-hydroxybenzoic acid (butyl paraben, BP) is a homologous series of parabens and is widely used as a preservative in cosmetic and pharmaceutical products. The purpose of this study was to investigate the estrogenic/antiandrogenic activities of BP in animals. For that, we performed an uterotrophic assay and a Hershberger assay in rats. In uterotrophic assay, BP was administered subcutaneously to immature female SD rats (18 days old) for 3 consecutive days. The wet and dry uterus weights were significantly increased in the groups treated with BP in dosedependent manner. In case of Hershberger assay, BP significantly reduced the weight of seminal vesicle of castrated rats. And other accessory organ/glands - prostate, Cowper's glands, bulbocavernosus muscle and glans penis were also slightly decreased. The results of this study suggested that BP showed estrogenic and anti-androgenic activities in vivo.
Ahn Tae Ran,Yoon Young Cheol,Kim Hyun Su,Kim Kyunga,Lee Ji Hyun 대한영상의학회 2023 Korean Journal of Radiology Vol.24 No.5
Objective: To investigate the association between pelvic bone computed tomography (CT)-derived body composition and patient outcomes in older adult patients who underwent surgery for proximal femur fractures. Materials and Methods: We retrospectively identified consecutive patients aged ≥ 65 years who underwent pelvic bone CT and subsequent surgery for proximal femur fractures between July 2018 and September 2021. Eight CT metrics were calculated from the cross-sectional area and attenuation of the subcutaneous fat and muscle, including the thigh subcutaneous fat (TSF) index, TSF attenuation, thigh muscle (TM) index, TM attenuation, gluteus maximus (GM) index, GM attenuation, gluteus medius and minimus (Gmm) index, and Gmm attenuation. The patients were dichotomized using the median value of each metric. Multivariable Cox regression and logistic regression models were used to determine the association between CT metrics with overall survival (OS) and postsurgical intensive care unit (ICU) admission, respectively. Results: A total of 372 patients (median age, 80.5 years; interquartile range, 76.0–85.0 years; 285 females) were included. TSF attenuation above the median (adjusted hazard ratio [HR], 2.39; 95% confidence interval [CI], 1.41–4.05), GM index below the median (adjusted HR, 2.63; 95% CI, 1.33–5.26), and Gmm index below the median (adjusted HR, 2.33; 95% CI, 1.12–4.55) were independently associated with shorter OS. TSF index (adjusted odds ratio [OR], 6.67; 95% CI, 3.13–14.29), GM index (adjusted OR, 3.45; 95% CI, 1.49–7.69), GM attenuation (adjusted OR, 2.33; 95% CI, 1.02–5.56), Gmm index (adjusted OR, 2.70; 95% CI, 1.22–5.88), and Gmm attenuation (adjusted OR, 2.22; 95% CI, 1.01–5.00) below the median were independently associated with ICU admission. Conclusion: In older adult patients who underwent surgery for proximal femur fracture, low muscle indices of the GM and gluteus medius/minimus obtained from their cross-sectional areas on preoperative pelvic bone CT were significant prognostic markers for predicting high mortality and postsurgical ICU admission.
Ahn, Jae-Jun,Kim, Gui-Ran,Akram, Kashif,Kim, Kyong-Su,Kwon, Joong-Ho Elsevier 2012 Radiation physics and chemistry Vol.81 No.8
<P><B>Abstract</B></P><P>The aim of this study was to determine the effects of light conditions during 2 years of storage on the luminescence characteristics of contaminating minerals, isolated from irradiated onions of 2 different origins. The potential use of photostimulated luminescence (PSL) as a screening and thermoluminescence (TL) as a confirmatory identification method was investigated during post-irradiation periods. Nonirradiated onions had 1,612 photon counts (PCs), However, the irradiated onions had much higher PCs (45,672–469,696, positive). The PCs of the irradiated onions decreased with storage time. However, all the irradiated onions had PCs with positive values (>5,000) even after 2 years of storage except onions stored under natural light. The decline in PCs because of light conditions during storage was in the order of sunlight, artificial light, and a darkroom, respectively. Minerals extracted from the nonirradiated samples exhibited TL glow curves of low intensities with maximum peak after 300<SUP>°</SUP>C. However, all irradiated samples had TL glow peaks in the temperature ranges of 185–225<SUP>°</SUP>C. The TL intensity and TL ratio of the irradiated samples decreased during storage with a slight shift in the TL peak temperature towards higher temperatures. The TL characteristics were most promising for samples stored under natural light conditions, however all the irradiated onions could be identified even after 2 years of storage.</P> <P><B>Highlights</B></P><P>► The luminescence properties are known sensitive to adverse storage conditions. ► Effect of storage under different light conditions on PSL & TL was evaluated. ► The most drastic effect was observed in case of storage under natural light. ► Identification was possible even after 2 years of storage using TL. ► The minerals were characterized using XRD analysis.</P>