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      • 흰 쥐의 뒷다리 현수 후 집중 체중부하 트레드밀 훈련과 전기자극이 골격근 특성에 미치는 효과

        안덕(Ahn Duck hyun),조상(Cho Sang Hyun),이충휘(Yi Chung hwi),강호석(Kang Ho Seok),권혁철(Kwon Hyuk cheol),김선엽(Kim Suhn yeop) 한국전문물리치료학회 2002 한국전문물리치료학회지 Vol.9 No.1

        The purpose of this study was to investigate the treatment effect of three interventions on the disuse atrophy of rat hindlimb after two weeks suspension. Forty-eight 11∼12 weeks old female Sprague-Dawley white rats were divided into four intervention groups: 1) suspension only (S; n=10), 2) intensive weight bearing treadmill (IWBT; n=10), 3) electrical stimulation (ES; n=9), 4) 2)+3) (ES/IWBT; n=9). Another 10 rats received no intervention or hindlimb suspension and served as controls (C). After the interventions, 1) the cross-sectional area (CSA), 2) the ration of white muscle fiber composition (WMFC), 3) isometric tetanic tension (ITT), and 4) muscle weights (MWs) were measured from the four calf muscle specimens. The results were as follows: 1. In all intervention groups, the CSAs of medial and lateral gastrocemius (MG•LG), soleus(SOL), and flexor digitorum superficialis (FDS) decreased when compared to the control (C) group (p<.05). The CSA increased in FDS and LG for the IWBF group, in SOL for the ES/IWBF group compared to the S only group (p<.05). 2, The rations of WMFC in MG, LG, SOL, and FDS in creased compared to the C group for all interventions (p<.05). The ratios of WMFC decreased in SOL and LG for the IWBT group, in SOL for the ES/IWBT group compared to the S only group, and decreased in SOL for the ES/IWBT group compared to the IWBT group(p<.05). 3. The ITT in the MG, LG, SOL, and FDS decreased compared to the C group for all interventions(p<.05). The ITT increased in MG•LG/FDS, SOL, and the whole calf muscles(WCMs) in the IWBT, ES and ES/IWBF groups compared to the S only group(p<.05). 4. The WMs in MG•LG/FDS, SOL, WCMs decreased compared to the C group for all interventions(p<.05). The MWs increased in MG•LG/FDS and WCMs for the IWBF group, in SOL for the ES group, and in SOL for the ES/IWBF group compared to the S only group(p<.05). 5. In atrophied muscles, the IWBT group showed the best recovery and the ES/IWBT and ES groups followed in decreasing order. The most susceptible muscle to disuse atrophy was the SOL. But conversely, it showed the best recovery in the ES/IWBT group. After two weeks of hindlimb suspension, the calf muscles of rats atrophied and their isometric tension decreased. These changes were best reversed by hindlimb-focused treadmill activity. The next best results were achieved by electrical stimulation combined with the tread mill followed by only electrical stimulation. These findings indicate that full weight bearing treadmill activity alone or in combination with electrical stimulation are effective treatments for non-weight bearing induced muscle atrophy. Further study of the effect of different intensities of electrical stimulation and variations in the duration period of full weight bearing treadmill activity on disuse atrophy is recommended.

      • KCI등재
      • KCI등재

        선행한 하기도감염 없이 발생한 폐쇄세기관지염의 임상 양상

        종효 ( Jong Hyo Hyun ),정지은 ( Ji Eun Jeong ),김영환 ( Young Hwan Kim ),장윤영 ( Yoon Young Jang ),정혜리 ( Hai Lee Chung ) 대한천식알레르기학회 2022 Allergy Asthma & Respiratory Disease Vol.10 No.2

        Purpose: We investigated young children who developed bronchiolitis obliterans (BO) without preceding severe lower respiratory tract infection (LRTI). Methods: Twenty patients referred for chronic respiratory symptoms and diagnosed with BO were enrolled and divided into 2 age groups: group 1 (<2 years, n=12) and group 2 (≥2, <6 years, n=8). A diagnosis of BO was made based on clinical and radiologic findings: (1) persistent cough or abnormal breath sounds which were not responsive to any treatment for more than 6 weeks; and (2) mosaic perfusion on high-resolution computed tomography. None of the subjects had experienced LRTI since birth, and those who had any underlying problems were excluded. The clinical characteristics and disease course were examined retrospectively. Results: Mean age of the patients was 6.8 months and 3.4 years in group 1 and 2, respectively. All patients presented with chronic cough and the most common type of cough was mixed (wet and dry), 67% in group 1 and 50% in group 2. Persistent stridor was the major respiratory sign in group 1 (67%), but 63% of group 2 patients showed no abnormal breath sounds. Chest x-ray finding was nonspecific in 75% each of both groups. The respiratory symptoms and signs resolved rapidly in most patients treated with pulse corticosteroid therapy. Bronchial hyperresponsiveness and decreased forced expiratory volume in 1 second were observed in 3 of group 2 children at age 6, during the follow-up. Conclusion: Our study shows that BO could develop without preceding severe LRTI. It also suggests that BO should be considered in the infants with persistent stridor accompanied by chronic cough. (Allergy Asthma Respir Dis 2022;10:89-96)

      • 가변 밸브 타이밍(VVA) 기구를 이용한 차세대 연소방식의 연구

        기수(Gisoo Hyun),정찬승(Chansung Chung),두병만(Byungman Doo),구영곤(Younggon Ku) 한국자동차공학회 2006 한국자동차공학회 춘 추계 학술대회 논문집 Vol.- No.-

        For this study, a Premixed Charged Compression Ignition (PCCI) Combustion was applied in a Heavy duty Diesel Engine, and has been experimentally investigated from the standpoint of its operating area extension to higher loads and engine performance, such like fuel consumption and emission, improvement. A Variable Valve Actuation (VVA) system was adopted to change the variables of intake and exhaust valve system such like opening, closing timing and valve lift profile. For controlling combustion timing which is a major difficulty for PCCI combustion engine realization, intake vale opening timing was advanced or retarded, and accordingly the effect of Miller cycle was evaluated. As a result, an ideal combustion can be achieved under controlling ignition timing and reducing effective compression ratio by using VVA system.

      • KCI등재

        단백자원으로서의 대두증산에 관한 연구 - 품종 파종기 및 석회시용량의 차이가 대두의 수량형질과 단백질 및 유분생육량에 미치는 영향 -

        신규,이은웅,이춘영,권용웅,S. K. Hyun,Eun-Woong Lee,Chung-Yong Lee,Yong-Woong Kwon 한국작물학회 1970 Korean journal of crop science Vol.- No.8

        단백자원으로서 가장 중요한 작물인 대두의 자실수량, 단백 및 유분수량이 품종별로 파종기 및 석회시용량의 차이에 따라서 어떻게 영양을 받는가를 구명하기 위하여 우리나라 중부지방의 주요대두품종 충북백, 육우 003 및 장단백목을 공시하여 파종기를 5월 22일(대두단작재배) 및 6월 11일(맥후작재배) 및 7월 1일 (만파재배)로 달리하고 석회시용량을 10a당, 0.5kg, 100kg으로 다르게 처리하여 본 시험을 1969년 서울대학교 농과대학 부속농장에서 실시하였다. 본 시험성적에서 나타난 대두의 수량형질, 단백 및 유분수량에 대한 결과를 요약하면 다음과 같다. 1. 공시된 품종중 육우003의 자실수량이 가장높았다는데 이는 육우003에 주당협수가 다른 품종보다 현저히 많다는 데에서 기인되었다. 단백함량은 충북백>육우003>장단백목의 순위였고 지유함량은 장단백목>충북백>육우003의 순위였으나 단위면적당 단백수량 및 지유수량은 자실수량이 많았던 륙우003가 가장 많았다. 그러나 이와같은 품종간 수량차이는 파종기에 따라서 각각 다르게 나타나고 있으므로 설계재배에 있어서는 품종과 파종기간의 관계를 크게 고려하여야 할 것이다. 2. 제1파종기와 제2파종기간에 자실수량차이는 없었으며 만파재배인 제3파종기에서는 자실수량이 현저히 감소되었다. 이와같은 현상은 제3파종기에서 1주당협수의 감소가 현저했기 때문으로 고찰된다. 단백질함량과 지유함량은 파종기에 따라 별로 변화하지는 않았으나 단백수량 및 지유수량은 제3파종기에서 자실수량의 감소와 함께 현저히 감소하였다. 3. 석회시용량의 증가에 따라서 분지수 협수가 증가하였으며 자실수량도 증가하였다. 본 시험에서는 자실수량이 석회 100kg/10a 시요구에서 가장 높았다. 단백함량도 석회시용량을 증가함에 따라 증가하였으나 지유함량은 석회무시용구가 가장 높았다. 단백수량은 석회시용량의 증가에 따라 자실수량 및 단백함량이 같이 증가되었기 때문에 현저히 증수되었으며 지유함량은 자실수량의 증가에 의해서만 증수되었다. 4. 수량형질간의 상관관계를 보면 경장과 주당경중, 100립중 및 자실수량간에 주당경중과 주당맥수 및 자실수량간에, 주당분지수와 100립중간에, 주당협수와 자실수량간에, 100립중과 단백함량간에는 고도의 정(+)의 상관관계를 인정할수 있었으며, 주당협수와 100립중간에는 부(-)의 상관관계가 있었다. To study the varital response of grain, protein and oil yield to different sowing dates and calcium levels in soybean, the most important crop as a protein source in Korea, this experiment was conducted in 1969. Three leading soybean varieties (Choongbukbaek, Ryooku#3 and Changdanbaekmok) were sown at May 22,, June 11 and July 1 under 3 different calcium levels, 0.50 and 100kg per 10a respectively. The results are summarized as follows: 1. Ryonku #3 showed the highest grain yield because of the highest number of pods per hill. In order of protein content, and oil content of grain, Choongbukbaek>Ryooku#3>Changdanbaekmok and Changdanbaekmok>Choogbukbaek>Ryooku#3 were found. Ryooku#3 also showed the highest protein and oil production per unit area owing to the highest grain yield. However. varietal differences of the grain yield the protein and the oil production per unit area varied along the different sowing dates. Interactions between varieties and sowing date on the grain yield should be considered in practice. 2. No difference in the grain yield was found between the first sowing date (May22) and the second (June11) on average. The grain yield in the plot of the third sowing date (July l)was strikingly decreased mainly by the smaller number of pods per hill. The protein and the oil content were not varied significantly by the different sowing dates. The protein and oil production per unit area were lowest in the plot of the third sowing date owing to the decreased grain yield. 3. More calcium application increased the number of branches per hill, the number of pods per hill, and the grain yield. The highest grain yield was found in the plot received 100 kg of calcium hydroxide per 10are. Protein content increased in higher calcium level, but oil content was highest in the plot of noncalcium. More protein production per unit area was gotten by more calcium application because of higher grain yield and protein content. all production increased in higher calcium level by the increased grain yield. 4. High plus (+) correlation was found between stem length and stem weight per hill stem length and grain weight, stem length and grain yield, stem weight per hill and number of pods per hill and grain weight, number of branches per hill and grain weight, number of pods per hill and grain yield, and grain weight and protein content of grain. Minus(-) correlation was recognized between number of pods per hill and grain weight.

      • SCOPUSKCI등재
      • KCI등재

        Groundwater Ubiquity Score를 이용한 제주도 토양 특성별 농약의 지하수 오염가능성 평가

        해남(Hae-Nam Hyun),장공만(Gong-Man Jang),오상실(Sang-Sil Oh),정종배(Jong-Bae Chung) 한국농약과학회 2007 농약과학회지 Vol.11 No.3

        One of the most recent issues facing the pesticides regulatory process is the assessment of the potential for pesticides to leach through soil and appear in groundwater. Since Jeju island depends on a hydrogeologically vulnerable aquifer system as its principle source of drinking water, it is important to identify which pesticides are the most likely to result in groundwater contamination. The objective of this study was to assess groundwater contamination risk of 21 pesticides (12 insecticides, 6 herbicides and 3 fungicides) in Jeju soils using groundwater ubiquity score (GUS). Considering GUS estimated in 21 representative series of Jeju soils, generally herbicides showed relatively higher leaching potentials and insecticides showed lower leaching potentials. Groundwater contamination risk was higher in the order of bromacil > metolachlor > alachlor > linuron pretilachlor > butachlor for herbicides, carbofuran > ethoprophos > diazinone > dimethoate > penthoate > mecarbam > methidathion > endosulfan > fenitrothion > parathion > chlorpyrifos > terbufos for insecticides, and metalaxyl > chlorothalonil > triadimefon for fungicides. Among the tested pesticides alachlor, metolachlor, bromacil, ethoprophos and carbofuran were classified as the pesticides of very high or high groundwater contamination potential. Although the ranking of the leaching potential was essentially determined on the base of the intrinsic properties of the chemicals and environmental properties, variation of the relative groundwater contamination potentials of each pesticides in different soils were not significant. Therefore, the above ranking of groundwater contamination risk would be applied in most of Jeju soils. To lower the possibility of pesticide contamination of groundwater, the use of those pesticides classified as high or very high leaching potential should be strictly regulated in Jeju Island.

      • KCI등재

        디지털 매체품질이 학습만족과 지속이용의도에 미치는 영향

        영란(Young-Ran Hyun),정소연(So-Yeon Chung) 한국콘텐츠학회 2016 한국콘텐츠학회논문지 Vol.16 No.11

        본 연구는 디지털 매체를 통한 고전문학의 원소스 멀티유즈(One Source Multi Use)의 활성화를 위해 매체품질에 대해 고찰하였다. 한국향토문화전자대전(www.grandculture.net)(향토DB)는 전국 234개 시 · 군 · 구의 향토문화 자료와 함께 설화, 민요 등이 구축되어 있어 고전문학의 OSMU가 가능한 매체이다. 이에 IS 성공모형을 적용하여 향토DB의 매체품질이 학습만족을 매개로 지속이용의도에 미치는 영향을 고찰하고자 고전문학수업을 받은 418명의 고등학생을 대상으로 설문조사를 실시하고 구조방정식을 사용해 분석하였다. 그 결과, 향토DB의 콘텐츠품질과 서비스품질은 학습만족을 매개로 지속이용의도에 영향을 미쳤으나 시스템품질의 학습만족에 대한 영향은 나타나지 않았다. 탐색적 다중회귀분석 결과, 시스템품질을 높게 인식하는 집단에서는 시스템품질의 학습만족에 대한 영향이 통계적으로 유의미하였으나 시스템품질을 낮게 인식하는 집단에서는 시스템품질의 학습만족에 대한 영향이 나타나지 않았다. 이러한 결과는 향토DB의 시스템품질이 향상되면 학습만족은 조금 강화되는 반면 콘텐츠품질과 서비스품질이 향상되면 학습만족은 상당히 활성화될 것임을 의미한다. This paper focus on the digital media quality of one source multi-use for the vitalization of Korean classical literature. This paper examines the structural relationship between the quality of digital media and learning satisfaction/sustainable use intention through digital media. For this we used the case of The ‘Encyclopedia of Korean Local Culture(www.grandculture.net)’. Thus we conducted a survey of 418 high school students attending a classical literature class which used the local culture DB. The result of this study demonstrates that quality of media content and media service quality affect the learning satisfaction even if media system quality does not affect the learning satisfaction. Learning satisfaction affect strongly. The result of multi regression showed that system quality increased the learning satisfaction in the high group, but system quality did not effect the learning satisfaction in the low group. These results indicate that if system quality is enhanced, learning satisfaction will be slightly increased, and if quality of contents and services is enhanced, learning satisfaction will be strongly increased.

      • KCI등재

        매체통합 고전문학수업에서 매체풍부성과 매체경험이 매체유용성과 학습몰입에 미치는 영향 연구

        영란,정소연,Hyun, Young-Ran,Chung, So-Yeon 한국도서관정보학회 2015 한국도서관정보학회지 Vol.46 No.4

        본 연구는 창의인재교육 관점에서 고전문학수업에서 매체통합교육에 있어 매체풍부성과 매체경험이 매체유용성과 학습몰입과 어떤 상관성이 있는지 살펴본 것이다. 이를 위해 전국 234개 시군구의 향토문화 자료를 집대성하고 이를 디지털화하여 서비스하는 웹매체인 한국향토문화전자대전(www.grandculture.net)(향토DB)를 활용한 수업을 받은 418명의 고등학생을 대상으로 설문조사를 실시하여 가설 설정, 타당도 검증, 인과모형을 도출하여 구조방정식을 분석한 결과, 향토DB의 매체풍부성과 학습자의 매체경험은 학습몰입에 주요한 영향임을 확인할 수 있었다. 또한 매체풍부성과 학습자의 매체유용성을 매개한 간접효과도 통계적으로 유의하였다. 따라서 향토DB와 같은 전국의 시군구 자료를 집대성한 웹매체의 적극적 발굴과 고전문학수업에서의 활용이 창의인재교육을 위한 매체통합교육에 유용함을 확인할 수 있었다. The purpose of this paper is to examine the structural relationship between the use of a web medium and learning commitment to develop creative talent for higher media integrated Korean classical literature education. For this we used DBs of The 'Encyclopedia of Korean Local Culture(a local culture DB)' built by the Academy of Korean Studies, and a survey was conducted on 418 high school students, attending a classical literature class which used a local culture DB. The result of this study demonstrates media usefulness of local culture DBs' positive effect on learning commitment. Specifically, media richness and media experience affects the learning commitment through the medium usefulness. These results indicate that in order to encourage learner's medium experience and increase medium richness it is necessary to increase the utilization of mediums, such as local culture DBs.

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