의약분업후 건강기능성식품이 약국경영에 미치는 영향

최병철,강효숙,곽현수,손의동,Choi, Byung-Chul,Kang, Hyo-Sook,Kwak, Hyun-Soo,Sohn, Uy-Dong 대한약학회 2009 약학회지 Vol.53 No.2

The purpose of this study is to investigate the best way that health functional food contributes the diversification of pharmacy management at the new point after the separation of prescribing and dispensing practice. In the question of the number of prescription paper, it was more than 200 papers (18.9%), next 100 papers (11.3%). In case of daily total sales volume except prescription fee, it was more than 1,000,000won (28.3%). About the motivation using health functional food, the reason for activation of pharmacy management was 66%. The selling method was mainly by pharmacist recommendation and consumer's need. In comparison with after and before the separation of prescribing and dispensing, more than 60% of subjects answered that sales volume was decreased and no changed. Concerning the ratio of total sales volume to health functional food within 5 years, 66% of subjects expected that it will be increased positively. The type of best pharmacy to handle health functional food was community pharmacy. These results suggest that the handling of health functional food by pharmacist will greatly increase in near futures and will be very important portion for pharmacy management.

스퍼터링 타겟용 저온 분사 Cu-15 at.%Ga 코팅 소재의 특성에 미치는 열처리 분위기의 영향

최병철,박동용,김형준,오익현,이기안,Choi, Byung-Chul,Park, Dong-Yong,Kim, Hyung-Jun,Oh, Ik-Hyun,Lee, Kee-Ahn 한국분말야금학회 2011 한국분말재료학회지 (KPMI) Vol.18 No.6

This study attempted to manufacture a Cu-15 at.%Ga coating layer via the cold spray process and investigated the effect of heat treatment environment on the properties of cold sprayed coating material. Three kinds of heat treatment environments, $5%H_2$+argon, pure argon, and vacuum were used in this study. Annealing treatments were conducted at $200{\sim}800^{\circ}C$/1 hr. With the cold sprayed coating layer, pure ${\alpha}$-Cu and small amounts of $Ga_2O_3$ were detected in the XRD, EDS, EPMA analyses. Porosity significantly decreased and hardness also decreased with increasing annealing temperature. The inhomogeneous dendritic microstructure of cold sprayed coating material changed to the homogeneous and dense one (microstructural evolution) with annealing heat treatment. Oxides near the interface of particles could be reduced by heat treatment especially in vacuum and argon environments. Vacuum environment during heat treatment was suggested to be most effective one to improve the densification and purification properties of cold sprayed Cu-15 at.%Ga coating material.

Raw 264.7 세포에서 유해산소 생성에 미치는 Caffeic Acid의 영향

최병철,Choi, Byung-Chul 대한약학회 2008 약학회지 Vol.52 No.6

To investigate effect of caffeic acid on the intracellular reactive oxygen species production, we used DHE for intracellular superoxide anion production, DCF for intracellular ${H_2}{O_2}$ production and DHR for intracellular hydroperoxide production in Raw 264.7 cells. DPPH assay showed that antioxidant activity of caffeic acid with 39.5 ${\mu}M$ of ${IC}_{50}$ values was similar to that of ascorbic acid with 41.3 ${\mu}M$ of ${IC}_{50}$ values. Caffeic acid dose-dependently inhibited silica-induced ${H_2}{O_2}$ and hydroperoxide production but did not affect superoxide anion production in Raw 264.7 cells, which suggest that antioxidant effect of caffeic acid acts on the post-step of superoxide anion. On the other hand, caffeic acid showed a potent antioxidant effect in $lCuSO_4$-induced lipid peroxidation. Furthermore, plasma superoxide dismutase activity (3.43${\pm}$0.23 U/ml) in 10 mg/kg caffeic acid-fed mice was significantly higher than that (2.32${\pm}$0.24 U/ml) of control. From the above results, it is referred that caffeic acid appears to have potent anti-oxidant activity in both cell system and in vivo system.

의약분업에 따른 약국 한약 활성화에 대한 조사 연구

최병철,김지인,손의동,Choi, Byung-Chul,Kim, Ji-In,Sohn, Uy-Dong 대한약학회 2008 약학회지 Vol.52 No.6

The purpose of this study is to investigate the best way that Oriental medicine contributes for activation of pharmacy management after the separation of prescribing and dispensing practice since July 2000. In order to investigate current pharmacy conditions for handling of Oriental medicine and many problems for administering the Oriental medicine to patients, a questionnaire was written with a list of questions related to pharmacy management with Oriental medicine, and given to 58 subjects via fax or personal visit during the period of April 21 to 30, 2003. The research results was as follows; In th 58 subjects, 45 subjects (77.6%) were pharmacists with a licence for dispensing Oriental medicine. 70.7% of subjects most likely preferred to extract granule as administering type of oriental medicine. About the motivation using Oriental medicine, the reason for activation of pharmacy management was 39.7%, second, the reason for resolving the limitation of treatment over western medicine was 25.9%. Oriental medicine for patients was mainly administered by recommendation with pharmacist (65.5%). In comparison with after and before the separation of prescribing and dispensing, 51.7% of subjects answered that sale volume was decreased after the separation. Concerning the ratio of total sales volume to Oriental medicine within 5 years, 50% of subjects expected that sales volume will increase positively. About treating Oriental medcine, 34.5% of subjects thought the problem is the regulation by limiting 100 kinds of formulary. The most important factor for increasing Oriental medicine selling amount was continueous education for various information of oriental medicine in case of 44.8% of sujects. The best pharmacy to handle oriental medicine was community pharmacy (36.2%). It was expressed the reason why many pharmacists have not been treated oriental medicine because lots of time needs for dispensing prescription from clinics in these 4 years after the separation of prescribing and dispensing. These results lead to the conclusion that the Oriental medicine at pharmacy will greatly increase within 5 years and will be very important portion for pharmacy management.

Ni, Ru-ZSM-5를 첨가한 NSR 촉매의 NOx 정화 특성

최병철,이춘희,정종우,Choi, Byung-Chul,Lee, Choon-Hee,Jeong, Jong-Woo 한국자동차공학회 2007 한국 자동차공학회논문집 Vol.15 No.5

In this study, we investigated the conversion performance of de-NOx catalyst for lean-burn natural gas engine. As a de-NOx catalyst, NOx storage reduction catalyst was composed of Pt, Pd and Rh with washcoat including Ba and Ni, Ru-ZSM-5. Ni, Ru-ZSM-5, which was regarded as a NOx direct decomposition catalyst, was made up of ion exchanged ZSM-5 by 5wt.% Ni or Ru. The performance of de-NOx catalyst was evaluated by NOx storage capacity and catalytic reduction in air/fuel, $\lambda=1.6$. The catalytic reaction was also observed when the added fuel was supplied to fuel rich atmosphere by fuel spike period of 5 seconds. The NOx conversion of the catalysts with Ni-ZSM-5 or Ru-ZSM-5 was mainly caused by the effect of NOx adsorption of Ba rather than the catalytic reduction of Ni, Ru-ZSM-5. Ni, Ru-ZSM-5 catalysts can not use for the NSR catalyst because they have quick process in thermal deactivation.

PLATFORM LEADERSHIP IN BUSINESS ECOSYSTEM AND RESOURCE DEPENDENCE THEORY

최병철 ( Byung Chul Choi ),김승범 ( Seung Beom Kim ),( Kenny Phan ) 한국경영공학회 2014 한국경영공학회지 Vol.19 No.4

In a business ecosystem, the platform leader takes on a role of overcoming main technological challenges and creating an innovative business model for the members of the ecosystem. Although the role of the platform leader and concepts of the ecosystem have been developed by a number of authors, it still lacks a precise theoretical support to understand what enables the platform leader to obtain and maintain (formal or informal) hegemony in the ecosystem. In this study, we develop a theoretical framework to understand the fundamental strategic intentions of the platform leader and suggest that resource dependence theory (RDT) provides more precise understanding of the leader and the other agents of the ecosystem. We also propose that the power of the platform leader is related to the degree of dependence on the other agents of the ecosystem. We provide support for our proposition with examples observed in the U.S. IT industry where multiple platform leaders exist and manage different types of platform leadership.

동축류 제트에서 CH₄, C₂H₄, C₃H₈, n-C₄H₁₀, 그리고 CH₄-H₂에 대한 자발화된 층류부상화염의 특성

최병철(Byung Chul Choi),정석호(Suk Ho Chung) 한국자동차공학회 2008 한국자동차공학회 춘 추계 학술대회 논문집 Vol.- No.-

정적 연소실 내 R134a 및 메탄 예혼합 화염의 전파 특성

최병철(Byung Chul Choi),박준성(June Sung Park) 한국연소학회 2014 KOSCOSYMPOSIUM논문집 Vol.2014 No.11

처방조제지원시스템 시행에 따른 약사의 인지도 및 수용성에 대한 조사

최병철(Byung Chul Choi) 대한약학회 2009 약학회지 Vol.53 No.6

DUR (Drug Utilization Review) originally referred to the evaluation of drug usage details: however DUR refers to the system used to support the services of prescribing and dispensing through linking from Health Insurance Review and Assessment (HIRA) Service in Korea. HIRA is going to begin the DUR enforcement for extending to nationwide coverage after pilot test. Objectives: The aims for this study were to evaluate and clarify the current opinions of the pharmacists for the recognition and acceptance rates before nationwide coverage concerning DUR system. Methods: A 16-question-questionnaire was developed and pilot tested. For 40 days of survey by both on-line and fax paper, it was carried out on 80 pharmacists working at community pharmacy in Goyang-si, Gyeonggi-do. Results: Most of answers were broadly positive and interested in begining the DUR system and kept in mind that the goal of DUR is safety guarantee for people. On the other hand, most of answerers worry that delay of patient waiting time and inharmonious communication with doctors in DUR processing can be a major obstacle to begin the DUR system. Conclusion: To solve several problems, the most important things are to make good reciprocal relationships between doctors and pharmacists, investigate intervention tool to shorten patient waiting time, and activate educational program of inspecting items for the pharmacists.

광촉매를 이용한 자동차용 공기정화기에 관한 연구

최병철(Byung-Chul Choi),김종호(Jong-Ho Kim),임효종(Hyo-Jong Lim) 한국자동차공학회 2002 한국자동차공학회 지부 학술대회 논문집 Vol.- No.-

An experiment of a photo-catalytic reaction was conducted to investigate the possibility of the automotive air purifier for a cabin using the photo-catalyst (TiO₂). It was found that the conversion efficiency reached 33% of a maximum value at 8 hours of the photo-catalytic reaction, The reaction activity of the photo-catalyst was increased as TiO₂ coating thickness and the humidity of the ambient air increases.<br/> <br/>