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한국인의 기능성 소화불량증 환자에서의 증상관찰, 아형분류 및 이에 대한 시사프리드의 효과
최명규 ( Myung Gyu Choi ),최규완 ( Kyu Wan Choi ),김나영 ( Na Young Kim ),임선희 ( Seon Hee Lim ),이계희 ( Kye Heui Lee ),김성국 ( Sung Kook Kim ),최용환 ( Yong Hwan Choi ),송치욱 ( Chi Wook song ),김혜랑 ( Heu Rang Kim ),임창영 ( 대한소화기기능성질환·운동학회 1998 Journal of Neurogastroenterology and Motility (JNM Vol.4 No.1
Background/Aims : The aims of this study were to determine subgoups of functional dyspesia and to evaluate the short-term effect of cisapride in patients with functional dyspepsia in Korea. Methods . 1025 patients, with a mean age of 42.6 years, with symptoms of functional dyspepsia, were recruited consecutively and upper gastrointestinal symptoms were investigated by interview in 41 hospitals in Korea. In an open, multicenter trial, 1025 patients received Smg of cisapride three times a day (TID) for at least .2 weeks for the treatment of symptoms of functional dyspepsia. When necessary, the dose of cisapride was increased to 10mg TID and the duration of therapy was extended to 4 weeks. Results . The most frequently reported symptoms of functional dyspepsia were epigastric discomfort or fullness (85%), bloating (70%), belching (53%), early satiety (52%) and epigastric pain (46%) retrospectively. Subgroups of functional dyspepsia were as follows; dysmotility-like 73.5%, ulcer-like 39.7%, reflux-like 13.0%, and unspecified dyspepsia 14.0%. However, 33.2% of subjects with functional dyspepsia could be classified into more than one subgroup. Upper gastrointestinal symptoms were decreased to average 50.3% (range; 42.2 to 59.2%) after 2 weeks of cisapride treatment and to 25% (19.2 to 29.9%) after 4 weeks. cisapride therapy resulted in good or excellent improvement in 59.0% of the patients after two weeks, in 75% of patients after 4 weeks. Adverse events were occurred in 52 patients (5.8% of all patients), most commonly, loose stools or diarrhea (3.5%), abdominal pain (1.1%), and dizziness (0.3%). The majority of adverse events was mild and transient in nature and led to premature discontinuation of treatment in 4 patients. Conclusions . Although the majorities of patients with functional dyspepsia have dysmotility like symptoms in Korea, there is such overlap among the dyspepsia subgroups. Most patients responded well to a short therapeutic trial with cisapride without significant side effects.
양성 식도 협착의 치료에 있어서 내시경적 식도 확장술의 효과
김재규(Jae Gyu Kim),이국래(Kook Lae Lee),최문석(Moon Suk Choi),최일주(Il Ju Choi),김용태(Yong Tae Kim),최상운(Sang Woon Choi),정현채(Hyun Chae Jung),송인성(In Sung Song),최규완(Kyoo Wan Choi),김정룡(Chung Yong Kim) 대한내과학회 1995 대한내과학회지 Vol.49 No.1
N/A Objectives: Dilatation therapy of benign esophageal stricture is now standard therapy. Although bougienage is widely used to treat benign esophageal stricture, the long-term effectiveness and clinical course of bougienage are unknown. Thus, we performed this study to evaluate the long-term effectiveness and clinical course of bougienage in benign esophageal stricture. Methods: We reviewed the medical records of patients with benign esophageal stricture who were treated by bougienage from 1988 to 1991. They were diagnosed as benign esophageal stricture by history, radiologic finding, endoscopic finding and pathology. Results: 1) Bougienage of benign esophageal stricture were effective in terms of improvement of dysphagia in 89 % of 35 paients. The etiology of benign esphageal stricture did not influence the effectiveness of bougienage. 2) Kaplan-Meier analysis showed that cummulative recurrence rate was 79% during a projected 60 months follow-up and the interval of 50% recurrence was 12.2 months. 3) Regardless of severity of stricture, the additional dilatations were needed in 55% of 31 patients impoved by first bougienge and 68% of 22 patients followed 6 months or longer. 4) The perforation rate per patient was 23% and the procedure related perforation rate was 7%. They were treated successfully by surgery or conservative treatment. The bleeding which needed transfusion occurred in 1 patient. He was terated successfully by trans-arterial embolization. Conclusion: Bougienage is safe and short-term effective treatment for benign esophageal stricture and could be utilized as primary therapy for most stricture. But in terms of high recurrence and compliication rate, well-designed controlled studies compared with surgical treatment will be necessary to find out long-term effectiveness of bougienage.
김재규(Jae Gyu Kim),이우진(Woo Jin Lee),장동경(Dong Kyung Chang),이풍렬(Poong Lyul Rhee),이정상(Jeong Sang Lee),최상운(Sang Woon Choi),윤용범(Yong Bum Yoon),송인성(In Sung Song),최규완(Kyoo Wan Choi),김정룡(chung Yong Kim) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.2
Spontaneous rupture of the esophagus is a rare emergency that requires immediate diagno- sis and surgical treatment. Delay in diagnosis is common and is caused mostly by lack of knowledge of the disease and consequent tendency to diagnose cases as perforated peptic ulcer, pancreatitis and acute coronary disease, etc.. Mortality and morbidity increase propor- tionally to the time between esophageal perforation and adequate treatment. We experienced a case of spontaneous esophageal perforation after alcohol ingestion, The patient was 49 year old male, who complained of sudden epigastric pain, hematemesis follow- ing forceful vomiting 4 hours before visit to emergency room. Emergency gastrofibroscopy showed oval mucosal defect with dark brownish blood clot. Under the suspision of esophageal rupture, we performed ermegency esophagography, which revealed leakage of gastrograffin and also showed pneumomediastinum. Emergency thoracotomy was performed, and esophage- al tear was primarily repaired and the insertion of chest tubes was done. He was discharged with recovery 1 month later. (Korean J Gastroenterol 1994; 26: 332 336)
김수환(Soo-Hwan Kim),최규완(Gyu-Wan Choi),문종필(Jong-Fil Moon),김태훈(Tae-Hoon Kim),김주용(Ju-Yong Kim) 대한전기학회 2016 전기학회논문지 P Vol.65 No.3
DC microgrid system is attracted attention in the world, because DC distribution system is more energy efficient than AC distribution system. To analyse the contribution effects of distributed generation(DG) in LVDC distribution system through modeling the Rectifier, DC/DC converter, Energy Storage System(ESS) and Photovoltaic(PV). using PSCAD/EMTDC. This paper analyses fault response characteristics in LVDC distribution system according to the interconnection and islanding operation of DG. Based on research results on the paper, direction for development of fault current reduction method for LVDC distribution system is suggested.
김수환(Soo-Hwan Kim),최규완(Kyu-Wan Choi),박민규(Min-Gyu Park),문종필(Jong-Fil Moon),지평식(Pyeong-Shik Ji) 대한전기학회 2015 전기학회논문지 P Vol.64 No.3
Lights from cities have been a grateful outcome of industrialization and a barometer of how developed the city is. However, indiscriminate exposure to artificial lights caused displeasure to people, ecological crisis to the nature, and overuse of energy. for example, excessive light is cause serious diseases such as sleep disorders, cancer in human, declining populations caused by reducing the ability to reproduce for animals and Plant yield is reduced. Therefore, each local governments have came up with ordinances in accordance with the law 『Light Pollution Prevention Act』. Accordingly, we"ve analyzed current Chungcheongbuk-do’s current states investigation and reduction method proposed for the light pollution act.
흡수장애 증후군으로 나타난 악성림프종과 동반된 유전분증
김태헌(Tae Hun Kim),김재규(Jae Gyu Kim),장유현(Yoo Hyun Jang),송상용(Sang Yong Song),정현채(Hyun Chae Jung),송인성(In Sung Song),조한익(Han Ik Jo),김용일(Yong Il Kim),최규완(Kyoo Wan Choi),김정룡(Chung Yong Kim) 대한소화기학회 1995 대한소화기학회지 Vol.27 No.4
Amyloidosis is known as a disease that affects almost all organs, and may especially cause wides- pread damage to the gastrointestinal tract. Intestinal amyloid may cause motility disturbances with diarrhea or constipation, malabsorption, bleeding, and perforation. We report a case of systemic amyloidosis presenting as a malabsorption syndrome. A59-year old woman with abdominal pain and chronic diarrhea turned out to have malignant lymphoma, GI amyloidosis, monoclonal gammopathy, and malabsorption syndrome. Well differentiated lymphocytic lymphoma was diagnosed by bone marrow biopsy. Endoscopic biopsy tissues from duodenum and rectum showed typical electron microscopic and staining features of amyloidosis. Serum protein electrophoresis revealed IgG k monoclonal gammopathy. D-xylose test and a- anti-trypsin clearance test confirmed malabsorption and protein-losing enteropathy, respectively. (Korean J Gastroenterol 1995;27: 481-487)
이우진(Woo Jin Lee),최문석(Moon Suk Choi),김재규(Jae Gyu Kim),고광철(Kwang Cheol Koh),김용태(Yong Tae Kim),최상운(Sang Woon Choi),정현채(Hyun Chae Chung),송인성(In Sung Song),최규완(Kyoo Wan Choi),김정룡(chung Yong Kim) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.3
N/A To find out. The underlying diseases and clinical characteristics of the patients with intestnal infarction and also t.o evaluate how early the patients were rnanaged, the clinical records of fifteen cases with intestinal infarction were reviewed ret.rospectively..Jine cases were docu- mented to have infarction by surgery and six cases by angiography. The mean age v as 60 years(24 82) and t.he ratio of male to female was 1: 1.5. The most frequent underlying diseases were the at.rial fibrillation, diabetes mellitus and hyper t,ension. The most common symptoms were abdominal pain(100%), vomiting(60%), bloocly .t.ool and diarrhea. Physical examinat.ion showed abdominal tenderness(87%), decreased bowel sound, abdominal distention, abdominal rebound tenderness, fever and hypotensiori. Sm;ll intestine was only involved in 60%, large intestine only in 13%, and both small and large intestine in 27%. The most common site of vascular occlusion was superior mesenteric artcry(Roio!. T!n- operated six cases had collaterals on angiography and they improved only by conservative managernent. Massive gangrene of small and large int,estine was found in 4 cases ot' t.hc 9 >p erated cases and three of them died. The mean t.ime lapse from onset of sympt.om to operat.ion was 33 hours. Only one case was operated within 8 hours. Seven cases were operated aftcr 2:1 hours and three of them died. In conclusion, if patient.s with underlying cardiovascular diseases complain of acute abdomi- nal pain, intestinal infarction should be suspected and angiography or operation must be per- formed as soon as possible.(Korean J Gastroenterol 1994; 26: 444-450)