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- 저자 : 인병현(Byeong Hyun In) (검색결과 4 건)
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폐암에 의한 폐절제 후 운동부하 폐기능 검사 - 4 주 및 6 개월 추적검사 -
인병현(Byeong Hyun In),문성기(Sung Gi Moon),김현중(Hyun Jung Kim),김형식(Hyeong Sik Kim),이홍(Hong Lee),이길홍(Kil Hong Rhee),이흥범(Heung Bum Lee),이용철(Yong Chul Lee),이양근(Yang Keun Rhee) 대한내과학회 1998 대한내과학회지 Vol.54 No.3
N/A Objectives: At present, the overall incidence of lung cancer is increasing, causing the age-adjusted lung cancer death rate to double every 15 years. Surgical resection of the tumor offers the best prospect of long-term survival in patients with lung cancer. Accurate prediction of postoperative ventilatory function should be helpful in determining in which patients the risk of surgery are acceptable. Exercise pulmonary function test has been widely applied to objective measure of work capacity, and can be extremely helpful for investigating exertional dyspnea. But no attempt is made to assess the contribution of the lung to be resected to performance, and it has been advocated as an additional predictor of postoperative complications. The present investigation was designed to evaluate the factors such as FEV1, FVC, VEmax, Vo2max, anaerobic threshold, heart rate reserve, breathing reserve and the corelation between FEV1 and VO2max at 4 weeks and 6months after resection in patients with lung cancer. Methods : The eighteen of patients with lung cancer who considered surgically resectable underwent progressively incremental exercise test to symptom-limited stage before opera-tion, and also have done at surgical resection after 4 weeks, and 6 momths. Measurements were made of metabolic, cardiorespiratory, blood gases and symptoms during exercise test. Results: 1) There were significant decreases in FEV1, FVC, VC2max, VE max in 4 weeks operation and were more decreased in FEV1, FVC, VE max with significance, but fall in VO2max without significance in 6 month after operation. 2) There was a significant correlation between the decrease of FEV1 and that of VO2max in 6 month after operation. Conclusions This result suggests that change of FEV1 is a relatively useful predictor of change in exercise performance after lung resection in 6 month after operation.
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인병현 ( Byeong Hyun In ),이양덕 ( Yang Deok Lee ),이양근 ( Yang Keun Rhee ) 전북대학교 의과학연구소 2001 全北醫大論文集 Vol.25 No.2
연구 배경: 알레르기 질환에서 알레르겐을 확인하는 것은 알레르기 질환의 정확한 진단 뿐 아니라 그 원인적 치료를 위해 필요하다. 피부반응시험은 알레르기 질환의 원인 항원을 검색하는데 가장 기본적인 진단 도구로 사용되고 있으며, 국내외적으로 아토피 유무 판정과 역학적 조사를 비롯한 연구 목적으로도 널리 이용되는 방법이다. 그러나 연령이나 성별에 있어서 어떠한 차이가 있는지에 대해서는 연구가 미미한 실정이다. 저자들은 천식환자에서 피부단자 시험의 결과에 연령과 성이 어떠한 영향을 나타내는지를 알아보고자 이 연구를 시행하였다. 방법: 1998년 2월부터 2000년 2월 사이에 전북대학교병원 호흡기내과에서 기관지 천식으로 진단받은 570명의 환자를 대상으로 하였다. 피부단자시험은 영국 Bencard사의 제품을 이용하여 총 150여종 (흡인성 항원 97종, 음식물 항원 57종)의 알레르겐에 대하여 환자의 등에 시행하였다. 팽진의 평균 직경이 히스타민(1mg/ml)에 의한 대조반응과 비교하여 Northern (Scandinavian) Society에서 추천한 반정량 등급체계를 기준으로 2+이상을 양성으로 판정하였다. 결과: 피부단자시험결과, 내인성 천식은 275명 (남:134, 여:141)이었고 외인성 천식은 295명(남:144, 여:151)로 내인성 천식과 외인성 천식에서 남녀간 성비의 차이는 없었다. 외인성 천식환자에서 연령이 증가함에 따라 양성반응시험결과의 수가 감소하는 경향을 보였으나 성별에 따른 차이는 없었으며, 히스타민에 의한 팽진의 크기는 연령이 증가함에 따라 증가하였으나 성별에 따른 차이는 없었다. 결론: 본 연구에서는 피부단자시험의 결과가 연령에 의한 영향은 받았지만 성별에 따른 영향은 받지 않았다. Background: In clinical practice, the skin prick test is a commonly used procedure for assessing a specific sensitization. However, there were few data about the relationship between the atopy and age and sex. The purpose of the present study was to evaluate retrospectively the influence of aging process and sex on sensitization, determined by immediate hypersensitivity reaction. Method: We analyzed the skin prick test results of 570 asthma patients (265 males and 305 females) from February, 1998 to February, 2000. Subjects had a mean age of 55 ±7 (SD) yr. Skin prick tests were performed using 150 allergens (Bencard, U.K.); wheal size was measured at 20 min and compared with that produced by a histamine control. Skin prick test reactivity was defined as a mean wheal size ≥ 2+ according to Northern Society for Allergology recommended Semi-quantitative Grading Systems. Results: The following results were obtained. 1) 275 were intrinsic asthma (134 males and 141 females) and 295 were extrinsic asthma (144 males and 151 females). 2) Among the patients with extrinsic asthma, 32% had a mono-allergy, 22% were sensitized against two allergens, 16% against three, and 30% against four or more allergens. 3) The number of positive tests decreased with age. 4) There was no significant relation between the allergen sensitization and sex. 5) The size of the histamine-elicited reactions increased with age, but no differences were noted between males and females.
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Thin Glomerular Basement Membrane Disease를 동반한 베게너육아종증
황학진 ( Hak Jin Hwang ),손주익 ( Ju Ik Son ),인병현 ( Byeong Hyun In ),박용범 ( Yong Beom Park ),이수곤 ( Soo Kon Lee ),정현주 ( Hyeon Joo Jung ),송정식 ( Jung Sik Song ) 대한류마티스학회 2001 대한류마티스학회지 Vol.8 No.3
Wegener`s granulomatosis is a necrotizing, granulomatous vasculitis that involves multiple organs including the upper and lower respiratory tract and the kidney. The kidney initially exhibits focal necrotizing glomerulonephritis, which progresses to crescentic glomerulonephritis in Wegener`s granulomatosis. We experienced a case of Wegener`s granulmatosis which was associated with a thin glomerular basement membrane disease. The patient suffered from nasal stuffiness, recurrent serous otitis media, and tinnitus. Despite antibiotic therapy and ventral tube insertion, symptoms did not improve and hearing difficulty was aggravated. Ulcerative, necrotizing granulomatous inflammations with multinucleated giant cells were seen on nasal biopsy. She had recurrent microscopic hematuria and the renal biopsy findings by light and immunofluorescent microscopy did not reveal any abnormalities but diffuse thinning of the glomerular basement membrane (226nm) was observed by electronmicroscopy. With the above clinical findings and biopsy results, we diagnosed Wegener`s granulmatosis with thin glomerular basement membrane disease. Thin glomerular basement membrane disease, also called benign recurrent hematuria, is characterized by diffuse thinning of the glomerular basement membrane and hematuria. Weekly low-dose methotrexate together with prednisone was used as treatment regimen because nonglomerular microscopic hematuria may be the first sign of cyclophosphamide-induced renal toxicity. With the above combination therapy, she felt well-being sense and her hearing difficulty was also much improved. She has been treated as an outpatient with glucocorticoid.
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