복강경불임술후 속발된 난관임신에 대한 임상적 고찰

은대숙,임장배,이우조,이려일 대한산부인과학회 1987 Obstetrics & Gynecology Science Vol.30 No.3

양수천자 543 예의 세포유전학적 연구

은대숙(Dae Suk Eun),유양희(Yang Hee You),조주은(Ju Eun Cho) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.2

Objective : To analyze 543 cases of amniocentesis with indications, cytogenetic results. Method : This study includes 543 cases cytogenetic study results which amniocentesis to detect fetal chromosomal abnormality in the Cytogenetic Laboratory at Eun Hospital in Kwang-Ju from August 1996 to December 2000, as gestational ages, indications of amniocentesis, maternal age distributions, chromosome aberrations with cytogenetic results. The cytogenetic results of chromosome aberration was identified by parents inheritance and de novo karyotypes as parents periperal blood cytogenetic study. Results : Amniocentesis performed mostly from 15 weeks to 20 weeks of gestaional ages. Requested indication of amniocentesis presents abnormal maternal serum screening (37%), infertility (23%) and maternal old age ( 35) (17%). Chromosome aberration according to amniocentesis indication was suspected fetal anomaly by ultrasonogram (8.6%), previous family history (5.7%). Chormosome aberration following maternal ages, more 40 years old women were found highly 7.9%. The frequency of chromosome aberration was 5.5% but de novo chromosome aberration was 2.2%. Numerical aberration was overall new karyotypes (1.3%). Structural aberration was inheritance karyotypes (3.3%) and de novo karyotypes (0.9%). Conclusion : Amniocentesis is a effective diagnostic tools in fetal chromosome aberration. Indication of fetal chromosomal anormality by ultrasonography and advanced maternal ages is an important diagnostic method with chromosome aberrations. Prenatal fetal chromosome aberrations included inheritance and de novo karyotypes. Especially, identification of de novo chromosome aberrations may predict fetal anomaly and counsel the fetus for pregnant parents.

골반경하 질식 자궁적출술 500예에 대한 연구

서정호(Jung Ho Seo),은대숙(Dae Sook Eun) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.12

Objectives: To evaluate the effectiveness and the value of Laparoscopic Assisted Vaginal Hysterectomy, and to evaluate the possibility whether to replace abdominal hysterectomy to LAVH. Method: A retrospective study of the surgical procedure was performed by one team with one experienced laparoscopist. The operations were carried out in a private hospital, where operative laparoscopic set was available. All 500 patients underwent LAVH from March 1998 to March 1999 at the department of Obstetrics and Gynecology, Eun hospital. Patients were required hysterectomy for uterine fibroid, chronic pelvic pain and carcinoma in situ of cervix,. etc. Results: The average operating time was 56.4±11.8 minutes, and the mean estimated postoperative hemoglobin loss was 0.62±1.0 g/dL. The mean uterine weight was 223.9±129.7 gram (range from 60gram to 800gram). The most common pathologic finding was adenomyosis(59.6%),and the second most pathologic findig was uterine fibroid(47%). No serious complications occured, but 3 vault hematoma cases occured. The combined procedures were salpingoophorectomy, adhesiolysis, and anterior or posterior colporrhaphy, etc. Conclusions: LAVH that has been possible to replace abdominal hysterectomy, may be valuable for gynecologic uterine diseases, but the experience is important for laparoscopic surgery. The learning curve influences the results of surgery and incidence of complications. Therefore the procedure may only be carried out by experienced laparoscopists, then the maximum value and advantages of laparoscopic surgery can be obtained. Our experience indicates that LAVH is to reduce almost all incidence of abdominal hysterectomy(0.4%)

난관배양액이 처녀발생유기된 돼지난포란의 체외발달에 미치는 영향

문승주,이경호,김호,김창렬,은대숙,김광현,나진수,김재홍 全南大學校 農業科學技術硏究所 1997 農業科學技術硏究 Vol.32 No.-

본 연구는 난관배양액이 돼지수정란의 체외발달에 미치는 효과를 규명키 위하여 수행하였다. 돼지 미성숙 난포란은 TCM-199, Ham's F-10 그리고 Whitten's 배양액에 10% 난포액과 호르몬(PMSG : 10IU/㎖, HCG : 10IU/㎖)을 첨가 20시간 배양하고 호르몬을 첨가하지 않는 배양액에서 20시간 추가 배양하여 총 40시간동안 배양하여 체외성숙을 유도하였다. 체외성숙후 0.1% hyaluronidase로 난구세포를 제거하고 15% FCS가 함유된 TCM-199으로 3회 세척하고 TCM-199에 15% FCS와 10% ethanol 혼합액에 세척한 난자를 옮겨 10분간 배양 처녀발생을 유기하였다. 처녀발생 6시간후 전핵형성율은 체외성숙배양액으로 TCM-199을 사용했을 때 56.4%, Ham's F-10의 경우 58.3%, Whitten's 배양액의 경우 74.0%를 보였다. 처녀발생 유기 48시간째 난할율은 TCM-199을 사용했을 때 45.7%, Ham's F-10에서 45.4%, Whitten's배양액에서 39.2%를 보였으며 세종류의 배양액에 POCM을 첨가 배양했을 때 TCM-199에 44.8%, Ham's F-10에서 45.4%, Whitten's배양액에서 43.7%로 나타났다. 처녀발생육 난자를 96시간 체외배양시킨 결과 상실배 발달율이 POCM을 첨가 했을 때 첨가하지 않은 시험구에 비하여 유의적으로 높았다(P<0.05) The effect of porcine oviductal conditioned medium(POCM) on in vitro development of chemically activated porcine oocytes was studied. Porcine oocytes were cultured in TCM-199, Ham's F-10 and Whitten's medium with hormonal supplements for 20h and 40h additional culture without hormonal supplements. After in vitro maturation, the denuded oocytes were washed 3 times with TCM-199 contaning 15%(v/v) ethanol to induce pathenogenetic activation. At 6h after activation, pronuclea formation rates were 56.4% in TCM-199, 59.3% in Ham's F-10 and 74.0% in Whitten's maturation medium. At 48h after activation, 45.7%, 45.4% and 39.2% of oocytes claved in TCM-199, Ham's F-10 and Whitten's culture medium, respectively. And 44.8%, 45.5% and 43.7% of oocytes were claved in TCM-199, Ham;s F-10 and Whitten's culture medium supplemented with POCM, respectively. The rates of moular were higher in culture medium with POCM than without POCM at 96h after activation.(P<0.05)

난관액, 난관배양액 및 난포액이 돼지정자의 운동성과 수정능 획득에 미치는 영향

문승주,이경호,김호,은대숙,김창렬,김광현,나진수,김재홍 全南大學校 農業科學技術硏究所 1997 農業科學技術硏究 Vol.32 No.-

본 연구는 돼지 정자의 운동성과 첨체반응에 대한 난관액, 난관배양액 및 난포액의 효과를 조사하였다. 수정능획득배양액에 난관액(10%)을 첨가 공배양했을 때 정자의 운동성은 처리구에서 유의적으로 높았다(P<0.05). CTC 염색방법으로 정자의 첨체반응을 조사한 결과 난관액과 난포액이 첨가된 수정능획득 배양액에서 1.5, 3, 4.5시간동안 전배양을 실시하였을 때 정자의 첨체반응이 대조구에 비하여 유의적으로 높았으며(P<0.05), 난관배양액에서 1.5, 3, 4.5시간동안 전배양을 실시하였을때도 대조구에 비하여 정자첨체반응이 유의적으로 높았다(P<0.05). 이러한 연구결과는 난관과 난포액등에 함유되어있는 어떤인자가 정자의 운동성과 첨체반응율을 높힌다고 사료된다. The effects of oviductal fluid, oviductal conditioned medium and follicular fluid on porcine sperm mortility and capacitation were studied. The addition of oviductal fluid, oviductal conditioned medium and follicular fluid to the prefertilization medium increased sperm mortility(P<0.05). Chloroterracycline(CTC) flourescence patterns were used to determine incidence of acrosome reaction. The proportion of acrosome reaction increased when spermatozoa were exposed for 1.5, 3 and 4.5h to oviductal fluid and follicular fluid(P<0.05). In sperm-POCM(porcine oviductal conditioned medium) co-culture period of 4.5 h, acrosome reaction rates was higher than other groups(P<0.05). These results suggest that the factor(s) in secreation from oviduct and follicular fluid increased sperm mortility and acrosome reaction.

선행제왕절개 임부의 분만에 대한 임상적 고찰

임장배(JB Im),은대숙(DS Eun),김윤하(YH Kim),최호선(HS Choi) 대한산부인과학회 1987 Obstetrics & Gynecology Science Vol.30 No.1

1982년 10월부터 1986년 3월까지 185명의 선행제절 임부의 분만을 가능한한 시험분만하여 다음과 같은 결론을 얻었다. 1. 시험분만은 113예(61.1%)에서 시도되고 이중 경질분만 86예(76.1%)였고, 총제절예는 99예(53.5%)였다. 2. 계획제절적응증은 임부가 제절을 원하거나 난관결찰을 동시에 원했던 경우가 27예(37.5%)였고 다음은 선행제절술식이 자궁체부종절개인 경우가 13예(18.1%)순 이었다. 3. 선행제절적응에 따른 시험분만결과는 아두골반분균형이나 분만의 진행이 안된 예는 경질분만이 63.8%인데 반해 기타 적응군은 89.1%로 통계적으로 유의한 차이였다. 4. 자궁반흔상태는 시험분만군에 자궁열개가 1예(1.4%)있었지만 이는 계획제절군과 유의하지 않았다. 5. 시험분만군에서 교정조산기사망은 없었고 모성사망도 없었다. 이상의 성적으로 미루어 엄격히 선정된 선행제절임부의 시험분만은 비교적 안전하고 높은 성공률의 경질분만을 기대할 수 있으리라 생각된다. This study was investigated of the 185 cases of delivery after prefious cesarean section from October, 1982 to March, 1986 at the department of obstetrics and Gynecology, Chonnam University Hospital. The results were as follows; 1. 113(61.1%) cases were allowed to trial labor and successful transvaginal delivery was 86(76.1%) cases and total repeat cesarean section was 99(53.5%) cases. 2. Indications for repeat cesarean section before labor were wanted tubal ligation in 27(37.5%) cases and previous classic section in 13(18.1%) cases. 3. Success rate of trial labor by indication of previous cesarean section CPD/FTP showed 63.8% whereas group of other than CPD/FTP revealed 89.1%. 4. One case(1.4%) of uterine dehiscence among the cases of trial labor was encountered. 5. There was no corrected perinatal or maternal mortality mortality among the cases of trial labor. Judging from the results obtained, trial labor controlled with under strict indications could expect satisfactory outcome.

산후 우울 증상과 연관된 심리사회적, 산과적 변인에 대한 연구

김재원 ( Jae Won Kim ),김정화 ( Jeong Hwa Kim ),김병조 ( Byeong Jo Kim ),은대숙 ( Dae Sook Eun ),김헌 ( Heon Kim ),김정은 ( Jeong Eun Kim ),이경민 ( Gyoung Min Lee ),이현수 ( Hyun Soo Lee ),최진 ( Jin Choi ) 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.10

Objective : The purpose of this study is to examine the psychosocial and obstetric factors associated with postpartum depressive symptoms in Korea. Methods : At the 1-week postpartum visit, 61 postpartum women completed Edinburgh Postnatal Depression Scal

산후 4주의 우울 증상에 대한 심리사회적 및 산과적 예측변인에 대한 연구

김재원 ( Jae Won Kim ),김정화 ( Jeong Hwa Kim ),은대숙 ( Dae Sook Eun ),김헌 ( Heon Kim ) 대한산부인과학회 2005 Obstetrics & Gynecology Science Vol.48 No.4