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ELL이 아토피 피부염 유발 NC / Nga 생쥐의 비장내 면역 관련 인자에 미치는 영향
윤미영 ( Mi Young Yun ),노영희 ( Young Hee Noh ),신길란 ( Gil Ran Shin ),정광조 ( Kwang Jo Cheong ) 한국미용학회 2008 한국미용학회지 Vol.14 No.3
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by inflammatory cell infiltration in the skin. This study was performed to assess the therapeutic effects of ELL on the DNCB-induced dermatitis in NC / Nga mice. ELL significantly reduced the total number of immune cells in spleen of approximately 22.6% (p<0.05) decreased. ELL significantly suppressed the Th cells number of CD3+(5.1%), CD3+/CD69+(43.1%, p<0.05), CD4+/CD25+(45.4%, p<0.05), CD4+(50.9%, p<0.05) in spleen. ELL significantly suppressed the B cells number of CD19+(34.1%, p<0.001), B220+/IgE+(44.2%, p<0.05) in spleen. ELL significantly reduced the number of CD11b+/Gr-1+(22.9%, p<0.01) cells existing in spleen. ELL significantly decreased the invasion of CD4+ and CCR3+cell in ear tissue compared with control group by using immunohistochemical staining. Taken together, these findings suggested that ELL has an anti-allergic activity and this might be useful for the clinical application to treat allergic diseases such as atopic dermatitis.
윤미영 ( Mi Young Yun ),노영희 ( Young Hee Noh ),정광조 ( Kwang Jo Cheong ) 한국미용학회 2007 한국미용학회지 Vol.13 No.2
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by inflammatory cell infiltration in the skin. This study was performed to assess the therapeutic effects of RMC on the DNCB-induced dermatitis in NC / Nga mice. 1. RMC administration significantly reduced clinical dermatitis severity including pruritus, edema, eczematous and erythema. 2. Histological findings indicated that the thickening of epidermis / dermis and dermal infiltration of inflammatory cells including mast cells were dramatically reduced. 3. The level of IL-4 in CD3 / CD28 activated splenocyte was downregulated, whereas that of IFN-γ was increased. Furthermore, the expression of eotaxin2 and CCR3 in skin were significanlty decreased. These data suggest that RMC may be effective therapeutic agents for the treatment of AD.
윤미영(Yun Mi-young) 중국근현대사학회 2008 중국근현대사연구 Vol.38 No.-
In Chinese history, women have suffered oppression and discrimination under the feudalism for more two thousand years. They were on the unequal position in politics, economy and family. Since mid 19th century, the Chinese women's effort for liberation and equality has been connected with the Chinese modem revolution movements. K'ang Youwei's "Ta-t'ung shu" is a discussion on sexual equality consciousness. He speaks out against traditional image of female and significance in Confucianism. He also insisted woman's rights that was based on the natural rights of man and the theory of social evolution. He laid the theoretical foundation of modern feminism. For example, the following were among their findings: Logical Characteristics in the Formation of K'ang Youwei's "Ta-t'ung ' Idea, A Study of K'ang Youwei's Political Reform Thought: With Focus on 1898 Political Reform Movement, Articles announced at the second Sinology General Meeting: Sexual Equality Consciousness in K 'ang Youwei's "Ta-t'ung shu", The Women of Modem China and the Project of Nationalization. This thesis is to study the women's liberation thoughts from the final phase of Ch'ing dynasty to the beginning of Republic of China, mainly focusing on K'ang Youwei's thought and praxis, the forerunner of the women's liberation movement of modern China, During Hundred Days of Reform, K'ang Youwei appealed to Chinese women for the emancipation of women in China through campaigning "Movement for abolishing Chinese Footbinding" and establish a women's school. Considering situation, K 'ang Youwei can be evaluated as pioneer of women movement at that period from a standpoint that he integrated core matters for Feminism in China before "Chinese Revolution" and groped the solution for it. I will study out the realization of welfare society and women's political participation in modern China. His feminism means a wise mother and good wife and a wealthy country and a powerful army. Lastly, I will shed light on how females are participating in society and politics and focus on the problems that these change are causing.
윤미영 ( Yun Mi Young ) 한국미용학회 2012 한국미용학회지 Vol.18 No.5
Atopic dermatitis most often affects infants and young children, but it can continue into adulthood or first show up later in life. Antiinflammatory drugs including steroid compounds such as prednisone and dexamethasone are generally used for atopic dermatitis therapy. Acute effects of these medication are expected in many cases, but long-term cure is not guaranteed in most of the cases due to severe side effects. The clinical severity of atopic dermatitis disorders was defined by classifying into 4 steps. The symptoms were evaluated by observing skin dryness, eruption and injury on the body parts such as the ears, face, head and back. The sections were stained with H&E and toluidine blue to differentiate inflammation, edema and mast cell in epidermis, dermis, keratinocytes, neutrophils and eosinophils. Measurement of inflammation cytokines in the serum for IL-6 and TNF-α cytokines levels in the serum ELISA kit. Then, inhibitory effects of inflammatory cytokines in atopic dermatitis induced NC/Nga mice by hydrolyzed products of baicalein(BE) treatment were investigated. The present data showed that an application of hydrolyzed products of baicalein(BE) in atopic dermatitis induced NC/Nga mice produced significant improvement against Atopic Dermatitis development and favorable regulation of inflammatory cytokine related to hypersensitive immune responses in Atopic Dermatitis tissues.
윤미영 ( Mi-young Yun ),김혜원 ( Hye-won Kim ) 한국미용학회 2024 한국미용학회지 Vol.30 No.2
This study was conducted to study the effects of Trichosanthis Radix water extract (TR-W) and Trichosanthis Radix 60% ethanol extract (TR-E) on collagen production. As a result of conducting a cytotoxicity experiment on HDFn cells and RAW 264.7 cells, the experiment was conducted at a concentration of TR-W and TR-E at 100 mg/ml, which does not significantly affect the survival rate in HDF and RAW 264.7 cells. The effect on collagen synthesis ability showed an increase of 52% for the positive control group L-AA (vitamin C) 52% for TR-W 25% and TR-E 36% at 100 mg/ml proving its effect on collagen synthesis ability. In terms of inhibition of MMP-1 expression related to collagen damage L-AA (vitamin C) a positive control group, showed an inhibitory effect of 54%, and TR-W and TR-E showed an inhibitory effect of 72% and 68% at 100 mg/ml, thereby inhibiting collagen decomposition enzyme. MMP-1 was stably inhibited. Compared to Control, the free radical scavenging activity of L-AA (vitamin C) a positive control group, showed a scavenging activity of 108.4%, and in TR-W and TR-E, it showed an inhibitory effect of 93.4% and 98.2% at 100 mg/ml. In NO related to inflammation, showed an anti-inflammatory effect of 67.4% and 50.2% at a concentration of 100 mg/ml of TR-W and TR-E compared to the control group, which is expected to have a positive effect on collagen production due to inflammation. This study The results are judged to have the highest utility value as a functional cosmetic material considering the stability of the skin in the future.
Insecticidal activity of oriental medicinal plants against Myzus persicae
Ji Yun Min(민지윤),Jun Young Kim(김준영),Young Min Goo(구영민),Seung Kyu Ahn(안승규),Hyo Hyung Lee(이효형),Keon Hee Ko(고건희),Min Ji Kim(김민지),Yun Geun Kim(김윤근),Mi Young Yoon(윤미영),Gyeong Seon Kim(김경선),Kyeong Yeol Oh(오경 한국약용작물학회 2013 한국약용작물학회 학술대회논문집 Vol.2013 No.1