「굿모닝 미스터 오웰」을 보고

유준상 세계평화교수협의회 1984 廣場 Vol.1984 No.126

Single-dose Toxicity of Water-soluble Ginseng Pharmacopuncture Injected Intramuscularly in Rats

유준상,선승호,이광호,권기록 대한약침학회 2015 Journal of pharmacopuncture Vol.18 No.2

Objectives: Radix Ginseng has been traditionally used as an adaptogen that acts on the adrenal cortex and stimulates or relaxes the nervous system to restore emotional and physical balance and to improve well-being in cases of degenerative disease and/or old age. Radix Ginseng has been used for a long time, but the safety of ginseng pharmacopuncture needs testing. This study was done to analyze the single-dose toxicity of water- soluble ginseng pharmacopuncture (GP) intramuscular injections in rats. Methods: All experiments were performed at Biotoxtech, an institution authorized to perform non clinical studies under the regulations of Good Laboratory Practice (GLP). Each group contained 10 Sprague-Dawley rats, 5 males and 5 females. GP was prepared in a sterile room at the Korean Pharmacopuncture Institute under regulations of Good Manufacturing Practice (GMP). GP dosages were 0.1, 0.5 and 1.0 mL for the experimental groups; normal saline was administered to the control group. The animals general condition was examined daily for 14 days, and the rats were weighed on the starting day and at 3, 7 and 14 days after administration of the pharmacopuncture. Hematological and biochemis biochemistry tests and autopsies were done to test the toxicological effect of GP after 14 days. This study was performed with approval from the Institutional Animal Ethics Committee of Biotextech. Results: No deaths were found in this single-dose toxicity test of intramuscular injections of GP, and no significant changes in the general conditions, body weights, hematological and biochemistry tests, and autopsies were observed. The local injection site showed no changes. Based on these results, the lethal dose was assumed to be over 1.0 mL/animal in both sexes. Conclusion: These results suggest that GP is relatively safe. Further studies, including a repeated toxicity test, are needed to provide more concrete evidence for the safety of GP.

Objective and Subjective Voice Examination in Korean Medicine

유준상 대한약침학회 2014 Journal of pharmacopuncture Vol.17 No.3

Objectives: When a person speaks, voice problems usually include pain or discomfort and/or difficulties in terms of the pitch, the loudness and the quality of the voice. When patients with voice problems induced by stroke, Parkinson’s disease, and systemic diseases involving the voice are examined, generally, of the Four Diagnoses (四診), a Diagnosis of Hearing can be used in current Korean medicine. The effects of acupuncture and herb medicine on voice problems have been reported for over 20 years. However, when it comes to improvements, objective and subjective evaluation methods need to be explained. Methods: Subjective methods for evaluating voice were studied through a literature search of old medicinal books containing Korean medicine diagnostics, and an objective evaluation method using Praat software is presented. Results: Korean medicine doctors analyze the patient’s voice in clinical settings unconsciously on a daily basis. However, most voice diagnoses depend on the doctor’s subjective evaluation. Voice qualities can be evaluated by using the Eight Principles (八綱), including Yin-Yang; the Five Elements (Phases); the Grade, Roughness, Breathy, Asthenic, Strained (GRBAS) score, and the Visual Analogue Scale (VAS) as subjective methods, and an acoustic analysis using the Praat program can be used as an objective method. Conclusion: A more complete voice examination can be achieved by using subjective and objective methods at the same time. For an objective explanation and management of patient’s voice problems or systemic disorders, an objective method should be used in Korean medicine, which already has many subjective diagnostic methods. More research needs to be conducted, and more clinical evidence needs to be collected in the future.

소음인체질병증 임상진료지침: 소음병

유준상,전수형,이의주,Yu, Jun-Sang,Jeon, Soo-Hyung,Lee, Eui-Ju 사상체질의학회 2014 사상체질의학회지 Vol.26 No.1

Objectives This research was performed to establish the clinical practice guideline(CPG) for Lesser Yin Symptomatology of Soeumin disease. Methods Dongeui suse bowon(sinchuk edition), textbook for Sasang constitutional medicine, Clinical guidebook for Sasang constitutional medicine, and standardization reports on Sasang constitutional medicine and papers concerning symptomatology of Soeumin Disease, especially Lesser Yin Symptomatology was collected and classified. Additionally experts' conference was held to make agreement on the conflicting issues on a regular basis. Results & Conclusions There was no concerning paper on Lesser Yin Symptomatology. Experts' agreement was needed to establish the CPG. Lesser Yin pattern can be classified into 2 groups; Lesser Yin severe pattern and Lesser Yin critical pattern. There are Lesser Yin pattern accompanied abdominal pain and bowel irritability pattern and Lesser Yin pattern accompanied green tinged watery diarrhea pattern in Lesser Yin severe pattern. There are Visceral syncope pattern and Exuberant yin repelling yang pattern in Lesser Yin critical pattern. Lesser Yin symptomatology has several symptoms like abdominal pain and diarrhea, thirst, oral discomfort, chest discomfort, whole body pain, articular pain and coldness of hands and feet. Additionally there are abdominal pain and diarrhea in Lesser Yin symptomatology accompanied abdominal pain and bowel irritability pattern, there is green tinged watery diarrhea in Lesser Yin pattern accompanied green tinged watery diarrhea pattern and if this symptoms exacerbate, delirious speech and constipation can occur. There are restlessness and coldness on hands and feet in Visceral syncope pattern and severe restlessness and coldness on hands and feet and symptom which the patient cannot drink water in Exuberant yin repelling yang.

Intravenous Toxicity Study of Water-soluble Ginseng Pharmacopuncture in SD Rats

유준상,선승호,이광호,권기록 대한약침학회 2015 Journal of pharmacopuncture Vol.18 No.4

Objectives: Radix Ginseng has been used for thousandsof years to treat a wide variety of diseases. Radix ginsenghas also been used as a traditional medicine for boostingQi energy and tonifying the spleen and lungs. Traditionally,its effect could be obtained orally. Nowadays, anew method, the injection of herbal medicine, is beingused. This study was performed to investigate the single-dose intravenous toxicity of water-soluble ginsengpharmacopuncture (WSGP) in Sprague-Dawley (SD)rats. Methods: All experiments were carried out at Biotoxtech,an institute authorized to perform non-clinicalstudies under the regulation of Good Laboratory Practice(GLP). At the age of six weeks, 40 SD rats, 20 male ratsand 20 female rats, were allocated into one of 4 groupsaccording to the dosages they would receive. The WSGPwas prepared in the Korean Pharmacopuncture Instituteunder the regulation of Korea-Good ManufacturingPractice (K-GMP). Dosages of WSGP were 0.1, 0.5 and1.0 mL/animal for the experimental groups, and normalsaline was administered to the control group. The rat'sgeneral conditions and body weights, the results of their hematological and biochemistry tests, and their necropsyand histopathological findings were investigatedto identify the toxicological effect of WSGP injected intravenously. The effect was examined for 14 days afterthe WSGP injection. This study was performed underthe approval of the Institutional Animal Ethics Committeeof Biotoxtech. Results: No deaths were found in this single-dose toxicitytest on the intravenous injection of WSGP, and nosignificant changes in the rat's general conditions andbody weights, the results on their hematological andbiochemistry test, and their necropsy findings wereobserved during the test. The local area of the injectionsite showed minial change. The lethal dose wasassumed to be over 1.0 mL/animal in both sexes. Conclusion: These results indicate that WSGP is safeat dosages up to 1 mL/animal.

기업의 전자증거개시 대응을 위한 예측 부호화(Predictive Coding) 도구 적용 방안

유준상,임진희 한국정보관리학회 2016 정보관리학회지 Vol.33 No.4

As the domestic companies which have made inroads into foreign markets have more lawsuits, these companies’ demands for responding to E-Discovery are also increasing. E-Discovery, derived from Anglo-American law, is the system to find electronic evidences related to lawsuits among scattered electronic data within limited time, to review them as evidences, and to submit them. It is not difficult to find, select, review, and submit evidences within limited time given the reality that the domestic companies do not manage their records even though lots of electronic records are produced everyday. To reduce items to be reviewed and proceed the process efficiently is one of the most important tasks to win a lawsuit. The Predictive Coding is a computer assisted review instrument used in reviewing process of E-Discovery, which is to help companies review their own electronic data using mechanical learning. Predictive Coding is more efficient than the previous computer assister review tools and has a merit to select electronic data related to lawsuit. Through companies’ selection of efficient computer assisted review instrument and continuous records management, it is expected that time and cost for reviewing will be saved. Therefore, in for companies to respond to E-Discovery, it is required to seek the most effective method through introduction of the professional Predictive Coding solution and Business records management with consideration of time and cost. 해외에 진출한 국내기업의 소송 사례가 증가하면서 기업들의 전자증거개시제도의 대응에 대한 요구가 증가하고 있다. 영미법에서 유래된 제도인 전자증거개시제도는 절차 진행과정에서 여러 곳에 산재해 있는 전자적 정보들을 중 제한된 시간 내에 소송과 관련된 전자적 정보들을 찾아 증거자료로 검토하여 제출하는 제도이다. 이는 하루에도 수많은 전자기록이 생산되는 국내기업들의 기록관리가 잘 이루어지지 않고 있는 현실에서 제한된 시간 이내에 증거자료를 추리고 검토하여 제출하는 것은 쉽지 않은 일이다. 검토대상을 줄이고 검토과정을 효율적으로 진행하는 것은 소송에서 승소를 위한 가장 중요한 과제 중 하나이다. Predictive Coding은 전자증거개시 검토 과정에서 사용되는 도구로써 기계학습을 이용하여 기업들이 보유하고 있는 전자적 정보들의 검토를 도와주는 도구이다. Predictive Coding이 기존의 검색 도구보다 효율성이 높고 잠재적으로 소송과 관련된 전자적 정보를 추려내는데 강점이 있다고 판단된다. 기업의 효율적인 검색도구의 선택과 지속적인 기록관리를 통해 검토비용의 시간적, 비용적 절감을 꾀할 수 있을 것으로 예상된다. 따라서 기업은 전자증거개시 제도에 대응하기 위해서 시간과 비용적 측면을 고려한 전문적인 Predictive Coding 솔루션의 도입과 기업 기록관리를 통해 가장 효과적인 방법을 모색해야 할 것이다.

빠른 2차 성징이 우려되는 여아에 대한 사상의학적 치험 5례

유준상,Yu, Junsang 사상체질의학회 2017 사상체질의학회지 Vol.29 No.2

Objectives Five cases of early puberty patients were diagnosed and treated according to Sasang constitutional medicine. Methods Seven year-old girl and four nine year-old girls visited the children's development clinic and were diagnosed as Sasang constitutional types according to clinical investigations. Their breast stages were in the 2nd degree of SMR(sexual maturity rating). Three were Taeeumin and two were Soeumin, so they were prescribed according to their Sasang constitutional types and complaints. Results and Conclusions It could show that early puberty patients can be given treatments and managements according to Sasang constitutional medicine.

소양인 소양상풍증으로 진단한 군발두통 환자 치험 1례

유준상,Yu, Jun-sang 사상체질의학회 2016 사상체질의학회지 Vol.28 No.4

Objectives The symptom of nineteen-year-old male patient who had cluster headache was alleviated using Soyangin's diagnosis and treatment. Methods This patient was diagnosed as Soyangin in terms of QSCC II(Questionnaire of Sasang Constitutional Classification II) and ordinary symptoms and current symptoms. The disease pattern was diagnosed as Soyang-sangpung symptomology. The intensity of headache was assessed by VAS(Visual Analogue Scale). Results and Conclusions The patient's symptom was improved using Hyeongbangsabaek-san, acupuncture treatment and cupping treatment.

수준별 이동수업이 성적 변화에 미치는 영향에 대한 고등학생들의 인식 연구

유준상 인하대학교 교육연구소 2008 교육문화연구 Vol.14 No.1

This paper aims to explore students' attitudes on the effects of various fields of ability grouping-based education. These fields include individual learning habits, organizing of differentiated classes, learning atmosphere in a class, teaching activities, and students' evaluation for the classes and the differences of evaluation of the effective elements of ability grouping-based education according to the differentiated classes. In order to accomplish this purpose, 180 students in the second grade of a secondary school were selected to be examined. The survey was done by a questionnaire completed by 180 students and by interviews with 30 of them. The results are as follows:First, the students showed favorable attitudes about the teaching activities and individual learning habits. In the field of students' evaluation, they expressed neutral and unfavorable attitudes. Second, in the field of individual learning habits, the students showed favorable attitudes concerning all the subordinate questions. Third, in the field of organizing of differentiated classes, the data showed that there were more students who had favorable attitudes about the question of proper organizing of the classes. Fourth, concerning the effect of comfortable feeling from the ability grouping-based education, there were more students showing negative attitudes than positive ones. Fifth, concerning the improvement of understanding the lessons, there were more negative attitudes than positive. Concerning the teaching methods, appropriate usage of teaching materials, proper explanations of homework, and compliments from teachers, there were more students who showed positive attitudes, and so almost half of them had favorable attitudes. Sixth, concerning the appropriate classes to the students abilities, supplement from differentiated classes, increased conviction for the English study, and help from friends, the data showed that almost half of the students had neutral attitudes and there were more unfavorable attitudes than favorable ones. But concerning the appropriate test according to the differentiated classes, almost half of the students showed neutral attitudes and there were more favorable attitudes than unfavorable ones. Seventh, in the analysis of the differences of evaluation of the effective elements of ability grouping-based education according to the differentiated classes, upper class students thought that learning atmosphere in a classroom had more positive effects on improving English grades than middle class students. They also thought that individual learning habits had more positive effects on improving English grades than middle and low class students. Now I would like to make some suggestions to heighten the efficiency of ability grouping-based education. Firstly, engage students to understand the true meaning of it and participate in the classes with a comfortable and eager mind. Secondly, teachers should try to do their best to develop the effective materials and teaching methods and care for the emotional problems of the students as well. Thirdly, teachers have to pay much more attention to the lower class students who are a kind of isolated class and provide positive reinforcement by giving compliments and encouragement. Lastly, through academic and career counseling with parents, positive support from parents and developing the learning programs with a local community, a school should provide a favorable educational environment for students. 본 연구에서는 교육과학기술부의 학교자율화 추진계획에 의거 전국적으로 확대될 것으로 예상되는 수준별 이동수업과 관련하여 고등학교 2학년 180명의 학생을 대상으로 한 설문지와 18명을 대상으로 한 인터뷰를 통해 개인의 학습 성항, 수준별 학급 편성, 학습활동 분위기, 교사의 교수 활동, 학생들의 수업평가 등이 성적 향상에 미치는 영향에 대한 학생들의 인식이 어떻게 나타나는지 알아보았다. 첫째, 수준별 이동수업에 영향을 주는 5가지 영역 중 학생들은 교사의 교수활동 개인의 학습 영역 요인들이 긍정적 영향을 주었다고 응답하였다. 학생들의 수업평가 영역은 보통과 부정적 평가가 많았다. 둘째, 영어 사교육 경험, 영어 교과에 대한 흥미, 희망 직업을 갖기 위한 노력, 부모님의 관심과 지도 등 모든 항목에 대하여 많은 학생들이 자신들의 영어 성적 향상에 긍정적 영향을 주었다고 응답하였다. 셋째, 수준별 학급 편성 요인들 중 적절한 수준별 학급 편성 요인의 성적 변화에 미친 영항은 긍정적 응답이 부정적 응답보다 많았다. 넷째, 수준별 이동수업으로 생성된 편안한 기분의 영향은 긍정적 영흥을 주지 않았다는 응답이 많았다. 수준별 학급 편성이라 할지라도 중ㆎ하위 반으로 떨어지지 않아야한다 또는 나는 부족한 실력의 학급이이라는 새로운 형태의 긴장감이 조성되었다는 것을 알 수 있다. 다섯째, 수업 이해도가 높아져 영어 성적에 긍정적 영향을 주었다는 항목은 부정적 응답이 많았다. 그러나 담당교사의 수업방식, 적절한 자료 활용, 적절한 과제 제시, 칭찬과 격려 등의 요인들에 대해 긍정적 응답이 훨씬 많았고, 수준별 수업 담당교사의 수업에 대해 거의 절반의 학생들이 긍정적으로 응답하였다. 여섯째, 학습자의 학습능력에 알맞은 수준의 수업진행, 수준별 수업이 자신의 부족한 부분을 보충, 이동 수업으로 교과학습에 대한 자신감 증가, 수준별 이동 수업으로 친구의 도움을 받아 성적향상에 긍정적 영향을 주었다는 질문에 보통이 절반정도였고 부정적 응답이 많았다. 그러나 수준별 학급 편성에 따른 적절한 평가 실시에는 보통의 응답이 절반 정도였고 긍정적 응답이 많았다. 일곱째, 수준별 이동수업 학급에 따른 영향 요인들의 평가에서, 상급반 학생들이 중급반 학생들보다 학습 활동 분위기가 영어 성적 향상에 긍정적인 영향을 미친다고 응답했다. 개인별 학습 성향에 대해서도 상급반 학생들이 중급반과 하급반 학생들보다 성적 향상에 긍정적인 영향을 미친다고 생각하는 것으로 나타났다.

한의과대학 학생들의 맥진 임상실습 향상을 위한 제언

유준상 상지대학교 한의학연구소 2020 尙志韓醫論文集 Vol.8 No.1

Purpose: In this study, a pulse diagnosis was performed during clinical practice in the undergraduate course to find out the degree of agreement to accurately locate the pulse movement among 3 positions such as Chon, Gwan, and Cheok, plus floating, middle, and bottom area on each position. Method: A total of 57 students consisted of 10 groups of 5 or 6 students in each group. At the group meeting, each other's pulses were captured and the positions of the movements of the pulses were drawn on the four-line sheets. In the case of the pulse wave pattern of 5 persons, 3 or more persons, and the pulse wave pattern of 4 persons, 3 persons or more were accepted as having consistency. Results: Average consistency rate of pulse diagnosis ranged from 88% to 93%. The pulses at Gwan area had the highest degree of consistency, followed by Chon area and Cheok area. In the case of pulses at Cheok area, the degree of consistency was higher when lying down than when sitting down. It seems that the pulse-taking in the sitting position requires attention to measure Cheok area Conclusion: In the clinical practice during undergraduate curriculum, to improve the technical ability and to secure objectivity of the pulse diagnosis, it is thought that the practice should be carried out through more systematic planning and preparation in order to improve the technical skills of pulse diagnosis.