http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Re: Comment on “Parainfectious Anti-Glial Fibrillary Acidic Protein-Associated Meningoencephalitis”
유달라,안태범 대한파킨슨병및이상운동질환학회 2022 Journal Of Movement Disorders Vol.15 No.2
We appreciate the interest of the author and colleagues in ourcase report. The authors suggested that our case could be consideredas anti-glial fibrillary acidic protein (GFAP) autoimmuneencephalitis (AE) rather than ‘parainfectious’ AE.
유달라,최지현,Jin-Hee Im,Man Jin Kim,김한준,박상섭,전범석 대한파킨슨병및이상운동질환학회 2020 Journal Of Movement Disorders Vol.13 No.3
F-box only protein 7 (FBXO7) is a rare monogenic cause of hereditary Parkinson’s disease (PD) with an autosomal recessive mode of inheritance and a broad spectrum of clinical manifestations. Here, we report a de novo PD patient with onset at the age of 28 with novel compound heterozygous variants in the FBXO7 gene (c.1162C>T, p.Gln388X; c.80G>A, p.Arg27His). The clinical features of the patient were problematic impulse control disorder behaviors and pyromania, and pyramidal signs were negative. We describe the novel pathogenic variants of the FBXO7 gene with detailed clinical pictures to report the expanding genotypes and phenotypes of FBXO7-associated parkinsonism.
유달라,김한준,채종희,백선하,전범석 대한파킨슨병및이상운동질환학회 2019 Journal Of Movement Disorders Vol.12 No.3
Dystonia 24 (DYT24) is an autosomal dominant disease caused by ANO3 mutation encoding anoctamin 3 that is predominantly characterized as adult-onset craniocervical dystonia; DYT24 is frequently combined with tremor or myoclonus [1]. We recently reported a patient with the pathogenic variant of ANO3 (p.Ser651Asn) who presented with early onset generalized dystonia starting in the lower extremities at age 3 with the broadening phenotypic spectrum of DYT24 [2]. Here, we further report that the patient exhibited an excellent response to deep brain stimulation (DBS) at the internal globus pallidus (GPi).
유달라,Tae Beom Ahn 대한파킨슨병및이상운동질환학회 2024 Journal Of Movement Disorders Vol.17 No.1
Since the colon is a gastrointestinal system frequently loaded with alpha-synuclein (aSyn) in Parkinson’s disease (PD), the role of aSyn in the pathogenesis of SV is of interest. However, although SV was reported in some patients with PD, pathologic reports were rarely made, leaving the role of aSyn in SV undetermined.
Parainfectious Anti-Glial Fibrillary Acidic Protein-Associated Meningoencephalitis
주재영,유달라,안태범 대한파킨슨병및이상운동질환학회 2022 Journal Of Movement Disorders Vol.15 No.1
Movement disorders associated with glial fibrillary acidic protein (GFAP) autoantibodies have rarely been reported as ataxia or tremors. A 32-year-old man with headache and fever, initially diagnosed with viral meningoencephalitis, showed gradual improvement with empirical treatment. Two weeks after the illness, he suddenly developed orofacial, tongue, and neck dyskinesia accompanied by oculomotor abnormalities, which developed into severe generalized choreoballism. Brain magnetic resonance imaging (fluid-attenuated inversion recovery) showed signal hyperintensities in the bilateral globus pallidus interna. The clinical picture suggested an acute inflammatory trigger of secondary autoimmune encephalitis. The autoimmune antibody test was positive for GFAP, with the strongest reactivity in the cerebrospinal fluid (CSF) before treatment and decreased reactivity in serial CSF examinations during immunotherapy. Dyskinesia gradually improved to the extent that it could be controlled with only oral medications. This patient presented with parainfectious GFAP meningoencephalitis with distinctive clinical features and imaging findings.
합성 생식샘자극호르몬방출호르몬 피하주사후 양측 후두엽 뇌출혈로 발현된 가역적뇌혈관수축증후군
정인영,유달라,정철규,한문구 대한신경과학회 2017 대한신경과학회지 Vol.35 No.3
Reversible cerebral vasoconstriction syndrome (RCVS) is a heterogeneous group of cerebrovascular disease. The pathophysiology of RCVS is unknown, but a disturbance in cerebral vascular tone is one of hypothesis. Long-term use of Gonadotropin-releasing hormone (GnRH) agonists can induce a pseudomenopausal state in which estrogen production are suppressed. It might lead to reduced arterial relaxation by estrogen withdrawal. We report a case of RCVS after the injection of synthetic analogue of GnRH.
Spinal Myoclonus Responding to Continuous Intrathecal Morphine Pump
안정은,유달라,정기영,김종민,전범석,이명종 대한파킨슨병및이상운동질환학회 2017 Journal Of Movement Disorders Vol.10 No.3
Spinal myoclonus is a sudden, brief, and involuntary movement of segmental or propriospinal muscle groups. Spinal myoclonus has occasionally been reported in patients undergoing opioid therapy, but the pathophysiology of opioid-induced myoclonus has not been elucidated yet. Here, we present two patients with spinal segmental myoclonus secondary to ischemic and radiation myelopathy. Conventional medications did not help treat persistent myoclonus in both legs. Continuous intrathecal morphine infusion was implanted for pain control in one patient, which relieved spinal myoclonus entirely. This experience led to the application of this method with a second patient, leading to the same gratifying result. Spinal myoclonus reemerged as soon as the morphine pumps were off, which confirmed the therapeutic role of opioids. In contrast to the opioid-induced myoclonus, these cases show a benefit of opioids on spinal myoclonus, which could be explained by synaptic reorganization after pathologic insults in the spinal cord.
Alternating Hemiplegia of Childhood in Korea: a Case Report
신채원,유달라,김한준,전범석 대한의학회 2020 Journal of Korean medical science Vol.35 No.26
Alternating hemiplegia of childhood (AHC) is a rare neurodevelopmental disorder characterized by recurrent paroxysmal hemiplegic attacks that affect one or the other side of the body. Up to 74% of patients with AHC have a pathologic variant in the ATP1A3 gene. After the introduction of next-generation sequencing, intermediate cases and atypical cases have expanded the clinical spectrum of ATP1A3-related disorders. Herein, we report the first case of AHC in Korea. A 33-year-old man visited our hospital with recurrent hemiplegic and dystonic episode after his first birthday. He was completely normal between episodes and did not have any ataxia, but brain magnetic resonance imaging showed cerebellar atrophy. He also had pes planovalgus deformity. Whole exome sequencing revealed a heterozygous G947R variant in the ATP1A3 gene (c.2839G > C, rs398122887), which is a known pathologic variant. This atypical case of AHC demonstrates the importance of the clinical approach in diagnosing ATP1A3-related disorders.
박찬영,유달라,정인영,한문구 대한신경과학회 2017 대한신경과학회지 Vol.35 No.3
Traumatic subclavian artery injury is a rare complication of clavicular fracture. An arterial injury can present as a pseudoaneurysm, which can cause a hypercoagulable state, thrombus formation, deep vein thrombosis, and distal embolism. We report a case of subclavian artery pseudoaneurysm that presented as embolic stroke in a 81-year-old man at 2015 1 month after clavicular fracture.