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갑상선 부갑상선 적출 토끼에서 고장성 NaCl 및 CaCl₂ 용액의 혈관내 주입이 Na,K,Cl,Ca 및 PO₄의 뇨중 배설에 미치는 영향
우종원,최덕경 고려대학교 의과대학 1983 고려대 의대 잡지 Vol.20 No.1
This study was performed for the purpose of investigating the effect of intravenous administration of hypertonic NaCl and CaCl₂ solution upon urinary excretion of electrolytes in thyroparathyroidectomized(TPTX) rabbits. Experimental animals were divided into 5 groups, namely: normal control group(N=18) ; acute TPTX group, 3 days after TPTX(N=14); chronic TPTX group, to 10 days after TPTX(N=11); NaCl group, 205 mEq/L NaCl solution was infused to chronic TPTX group (n=9); CaCl₂ group, 400mEq/L was infused(N=9), 800 mEq/L CaCl₂ solution was infused additionally(N=8). When thyroparathyroids were taken away, synthyroids(0.2 ㎎/day) were administered to the rabbits for the maintenance of thyroid function. Hypertonic NaCl and CaCl₂ solutions were infused for an four by the rate of 0.8 ml/min. Serum and urinary electrolytes were measured before and after the infusion hypertonic solutions by the following methods: Na and K, flame photometry; Cl, Schales and Schales method; Ca, EDTA titration method and PO₄ by Fisk and SubbaRow method. The Serum findings; A. Serum findings; 1. Both in TPTX and NaCl group there were no significant changes in serum electrolytes concentration from those of control group. 2. In CaCl₂ group serum levels of Ca and Cl increased significantly, but serum PO₄ showed marked findings: 1. Urinary concentration of Na and Cl increased in both of NaCl and CaCl₂ group, more markedly in CaCl₂ group. 2. In TPTX group urinary K concentration increased but decreased in NaCl and CaCl₂ groups. 3. Urinary Ca decreased slightly In TPTX and NaCl groups, on the contrary in CaCl₂ group there was marked increase in urine Ca concentration. 4. TPTX group showed significant increase in PO₄ excretion, on the otherhand, NaCl and CaCl₂ groups showed marked decrease of them. From the above results it was suggested that serum Ca concentration might affect membrane permeability and electrolytes transport across the renal tubular cells.
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단일 주입법에 의한 Inulin clearance와 Hippuran I¹³¹ clearance에 대한 실험적 고찰
우종원,최덕경 고려대학교 의과대학 1980 고려대 의대 잡지 Vol.17 No.1
In the evaluation of glomerular filtration rate of the children or the small size animals such as rabbits and rats, there are many technically difficult problems in urine collection. So clearance was estimated by the calculation of the distributed volume and the disappearance rate in plasma of the indicator. Constant infusion method provides and effective technique for the evaluation of GFR and renal plasma flow rate without urine collection. Comparative experimental analyses between conventional method and constant infusion method in using inulin and hippuran-I¹³¹ were made in this experiment operated for the 21 normal male rabbits, weight about 2㎏; of which 10 for inulin clearance (Cin). 11 for hippuran-I¹³¹ clearance (C_(PAH-I)¹³¹). The results as follows : 1. The mean value of Cin obtained from conventional method was 1.69±0.59㎖/min. The mean value of Cin from theoretical method was 1.45±0.61㎖/min. in the case of 10 rabbits. Correlation coefficient was r=0.948, so regression line was defined by Y=0.916X+0.37. The result shows a correlation was highly significant. 2. The mean value of distributed volume of inulin was 548.10±136.60㎖, 26.49±5.42% of body weight. But the decay constant was 0.0028±0.001 by calculated from plasma inulin levels. 3. The mean value of C_(PAH-I)¹³¹ obtained from conventional method was 17.55±5.52㎖/min. The mean value of C_(PAH-I)¹³¹ from theoretical method was 17.80±5.79㎖/min. in the case of 11 rabbits. Correlation efficient was r=0.948, so regression line was defined by Y=0.903X+1.48. The result shows a correlation was highly significant. 4. The mean value of distributed volume of hippuran-I¹³¹ was 565.92±119.40㎖, but the decay constant was 0.0344±0.0176 by calculated from plasma hippuran-I¹³¹ levels.
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Dy 및 Mg가 첨가된 BaTiO<sub>3</sub>에서 소결 온도가 미세구조와 유전특성에 미치는 영향
우종원,김성현,최문희,전상채,Woo, Jong-Won,Kim, Sung-Hyun,Choi, Moon-Hee,Jeon, Sang-Chae 한국결정성장학회 2022 한국결정성장학회지 Vol.32 No.5
Rare-earth elements were doped with Mg to enhance the temperature stability of dielectric properties of BaTiO<sub>3</sub> for its application to MLCC (Multi-Layer Ceramic Capacitor). The additives strongly affect both grain growth and densification behaviors during sintering, and hence dielectric properties. The additive effects therefore should be examined in each system with different additives. This study investigated the crystal structure, grain growth and densification behaviors and related variations in dielectric constant with respect to sintering temperature. Dielectric constant appears to be varied with grain size in a temperature range between 1200 and 1300℃, suggesting the importance of grain size control. The temperature dependence of grain size variation was well explained by an established theory correlating the grain growth behavior with grain boundary structure. This accordance provides a basis for sintering technique to control grain growth thus to improve dielectric constant in rare-earth doped BaTiO<sub>3</sub>.
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세계화와 일본의 기업별조합 : ‘종업원주권’의 패러독스
우종원 서울대학교 일본연구소 2012 일본비평 Vol.- No.7
세계화의 진전 속에 일본사회의 양극화가 빠르게 진행되고 있다. 이 글은 세계화에 대한 일 본의 기업별조합을 대응을 분석하고, 기업별조합이 양극화를 저지하고 못한 이유와 그런 행동이 조합 자신에 초래한 귀결에 대해 문제를 제기한다. 세계화에 대해 일본기업은 투자 확대나 이노베이션 강화보다는 코스트삭감을 가속시키는 방향으로 대응했고, 이는 결과적으로 사회의 양극화를 초래했다. 기업별조합은 스스로 기 업통치의 한 축을 담당한 때문에 이런 기업행동을 용인하고, 비정규직문제에 대해서도 적극적으로 대응하지 않았다. 그러나 경영 및 조합의 이런 행동은 역설적으로 일본기업의 강 점이었던 ‘현장력’을 약화시켰을 가능성이 있다. A사의 사례에서 보여 주듯 고용삭감 속에 서의 비정규직 증대와 성과주의 임금관리의 강화는, 현장력의 주요한 요소인 여유를 직장 에서 빼앗는 한편으로, 직장내 커뮤니케이션을 약화시키고 있기 때문이다. 이런 ‘종업원주권’의 패러독스가 시사하는 바는 다음과 같다. “전(全)노동자의 연대와 사회 적 공정”이란 관점만으로 기업별조합의 행동 변화를 기대하거나 그것을 유도하기는 어렵 다. 오히려 ‘종업원주권’이 역설적으로 자신의 기반인 ‘현장력’을 약화시키고 있다는 점을 분석할 필요가 있고, 이것이 분명해질 때 기업별조합 스스로 행동을 변화시킬 가능성이 있 다 하겠다. In the age of globalization, the polarization made rapid progress in Japan. This paper examines how the Japanese enterprise unions dealt with the impact of globalization, why the unions could not stop the polarization, and what the result of union behaviors to the unions themselves would be. Japanese Companies chose their strategy which was not accelerating invest or innovation, but reinforcing cost-cutting, which brought about the decrease of regular workers, the increase of irregular workers, and the earnings differentials as a result. The enterprise unions that comprised with stockholders important stakeholders of corporations tolerated this kind of behavior. However, the cost cutting strategy and the following practices of employment/compensation management might lead to the erosion of workshops’ Kaisen-Power through putting an obstacle to smooth communication and taking workshops of time to carry out the Kaizen plans, as seen in the case study of A-Company. The Paradox of ‘employees as an important stakeholder’ implies: It is not enough to blame the ‘egoistic’ behaviors of enterprise unions on the viewpoint of solidarity and justice. Contrarily, it is needed to investigate the reality that the behaviors might weaken the Kaisen-Power of workshops, the very base of employees as an important stakeholder.
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