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RISS 인기검색어
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- 저자 : 심태석(Tae Seok Sim) (검색결과 11 건)
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Microbead based micro total analysis system for Hepatitis C detection
심태석(Tae Seok Sim),이보람(Bo-Rahm Lee),이상명(Sang-Myung Lee),김민수(Min-Soo Kim),이윤식(Yoon-Sik Lee),김병기(Byung Gee Kim),김용권(Yong-Kweon Kim) 대한전기학회 2006 대한전기학회 학술대회 논문집 Vol.2006 No.7
This paper describes a micro total analysis system (μ TAS) for detecting and digesting the target protein which includes a bead based temperature controllable microchip and computer based controllers for temperature and valve actuation. We firstly combined the temperature control function with a bead based microchip and realized the on-chip sequential reactions using two kinds of beads. The PEG-grafted bead, on which RNA aptamer was immobilized, was used for capturing and releasing the target protein. The target protein can be chosen by the type of RNA aptamer. In this paper, we used the RNA aptamer of HCV replicase. The trypsin coated bead was used for digesting the released protein prior to the matrix assisted laser desorption ionization time of flight mass spectrometer (MALDI TOF MS). Heat is applied for release of the captured protein binding on the bead, thermal denaturation and trypsin digestion. PDMS microchannel and PDMS micro pneumatic valves were also combined for the small volume liquid handling. The entire procedures for the detection and the digestion of the target protein were successfully carried out on a microchip without any other chemical treatment or off-chip handling using 20μl protein mixture within 20 min. We could acquire six matched peaks (7% sequence coverage) of HCV replicase.
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심재천(Jae-Cheon Sim),전종현(Jong-Hyun Jeon),서이락(Yi-Rak Seo),박대원(Dae-Won Park),남태석(Tae-Seok Nam) 대한정형외과학회 2018 대한정형외과학회지 Vol.53 No.5
목적: 외상력이 없는 젊은 남자의 무릎 자기공명영상을 통하여 정상적인 반월상 연골의 크기, 돌출의 정도, 동반 변형에 대해 알아보고자 하였다. 대상 및 방법: 슬관절을 제외한 타 부위의 동통을 주소로 정형외과 외래를 방문한 환자 중 연구 당시 슬관절 부위의 동통을 호소하지 않고, 슬관절 외상력이 없는 젊은 77명(91 슬관절)을 대상으로 하였다. 평균 나이는 21.6±1.1세(19-24세)였으며, 1.5Tesla magnetic resonance unit (Magneton Symphony; Siemens, Erlangen, Germany)을 이용하여 검사를 시행하였다. 이를 통하여 반월상 연골의 크기, 돌출, 돌출률, 동반 변형에 대해 알아보았다. 결과: 관상면에서 내측 반월상 연골의 평균 크기는 9.0±1.1 mm (7.1-11.9 mm), 돌출의 정도는 2.0±1.0 mm (0-4.4 mm), 반월상 연골 돌출률(돌출 크기/전체 크기×100)은 22.7%±11.5% (0%-53.7%)였다. 내측 반월상 연골의 돌출은 관상면과 시상면에서 각각 92.3%, 80.2%에서 관찰되었다. 관상면에서 외측 반월상 연골의 평균 크기는 11.1±3.4 mm (7.3-22.9 mm), 돌출의 정도는 0.5±0.7 mm (0-2.5 mm), 반월상 연골 돌출률은 4.0%±6.7% (0%-26.3%)였다. 외측 반월상 연골의 돌출은 관상면에서 34.1%에서 관찰되며, 시상면에서는 관찰되지 않았다. 결론: 외상 없는 젊은 환자의 자기공명영상 검사에서 반월상 연골의 돌출은 흔히 관찰되며, 외측보다 내측에서 더 흔하게 관찰된다. Purpose: The aim of this study was to assess the size and extrusion of the meniscus in young and non-traumatic knees, especially in Korean males. Materials and Methods: The participants (n=91 knees, 77 patients) were consecutive patients observed at an orthopedic outpatient clinic who had another problem unrelated to the knee joint. The patients were excluded from the study if they had a history of trauma and pain on the knee joint. The patients received a magnetic resonance imaging (MRI) scan on the knee joint. The size, extrusion, and extrusion ratio of the meniscus on an MRI scan were evaluated. Results: The mean age of the participants was 21.6±1.1 years (range, 19-24 years). The mean size of the medial meniscus on the coronal plane was 9.0±1.1 mm (range, 7.1-11.9 mm). The extent of extrusion on the coronal plane was 2.0±1.0 mm (range, 0-4.4 mm). The extrusion ratio (extruded size/total size×100) of the medial meniscus on the coronal plane was 22.7%±11.5% (range, 0%-53.7%). The extent of extrusion on the sagittal plane was 1.6±1.1 mm (range, 0-4.0 mm). The extrusion ratio (extruded size/total×100) of the medial meniscus on the sagittal plane was 18.0%±11.9% (range, 0%-40.7%). The incidence of medial meniscal extrusion on the coronal and sagittal plane are 92.3% and 80.2%, respectively. The mean size of lateral meniscus on the coronal plane was 11.1±3.4 mm (range, 7.3- 22.9 mm). The extent of extrusion on the sagittal plane was 0.5±0.7 mm (range, 0-2.5 mm). The extrusion ratio of the lateral meniscus on the sagittal plane was 4.0%±6.7% (range, 0%-26.3%). The incidence of lateral meniscal extrusion on the coronal plane was 34.1%. No extrusion of the lateral meniscus was observed on the sagittal plane. Conclusion: In young and non-traumatic knees, the extrusion of meniscus was common, especially medial meniscus than lateral meniscus.
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방용승(Yong-Seung Bang),심태석(Tae Seok Sim),김성현(Sung Hyun Kim),강성권(Sung Gwon Kang),김용권(Yong-Kweon Kim) 대한전기학회 2006 대한전기학회 학술대회 논문집 Vol.2006 No.7
This paper reports on a flexible and biocompatible platinum thermoresistive temperature sensor for the application of an ultrasonic resonance thrombolysis device for ischemic stroke. The proposed flexible platinum temperature sensor consists of a polyimide substrate, a platinum thermoresistive element and a polyimide insulation layer. The temperature coefficient of resistance (TCR) and sensitivity of the designed temperature sensor were measured and calculated to be 2.63×10?³/℃ and 0.93 ℃/sec, respectively.
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분절성 쇄골 골절의 수술적 치료와 비수술적 치료 - 증례 보고 -
하성식 ( Sung-sik Ha ),홍기도 ( Ki-do Hong ),심재천 ( Jae-cheon Sim ),서이락 ( Yi-rak Seo ),남태석 ( Tae-seok Nam ) 대한골절학회 2017 대한골절학회지 Vol.30 No.3
분절성 쇄골 골절은 매우 드물며, 그 치료 방법에 대해 명확히 정립되어 있지 않다. 분절성 쇄골 골절을 가진 환자에서 각각 보존적 치료를 시행한 예와 수술적 치료를 시행한 예를 통해 좋은 결과를 얻었던 2예를 보고자 한다. 또한 문헌 고찰을 통해 유사한 경우의 치료에 대해 논하고자 한다. Segmental fractures of the clavicle are very rare. Therefore, to date, there has not been a clear, standardized method of management of segmental clavicle fractures. Herein, two patients with a segmental fracture are described: One patient was treated conservatively, while another patient was treated operatively. Both patients showed excellent results. We discuss the various management options with a literature review.
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