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종설 : 우리나라 당뇨병의 역학적 특성 -대한당뇨병학회,건강보험심사평가원 공동연구 결과를 중심으로
박이병 ( Ie Byung Park ),백세현 ( Sei Hyun Baik ) 대한당뇨병학회 2009 Diabetes and Metabolism Journal Vol.33 No.5
The aim of article is to introduce the current status of diabetes care and characteristics in diabetic patients in Korea, which is a joint report by Korean Diabetes Association (KDA) and Health Insurance Review Agency (HIRA) ("Diabetes in Korea 2007") and to review the recent published data about the current status of diabetes mellitus in Korea. (Korean Diabetes J 33:357-362, 2009)
의예과 학생을 대상으로 한 팀워크 향상 프로그램의 효과
박귀화 ( Kwi Hwa Park ),박경혜 ( Kyung Hye Park ),박이병 ( Ie Byung Park ) 대한의료커뮤니케이션학회 2021 의료커뮤니케이션 Vol.16 No.2
Background: The purpose of this study is to conduct a teamwork program for pre-medical students using a table-top simulation game called Friday Night at the ER®, and to investigate the effect. Methods: This is a one group pretest-posttest design study 34 students. The tools were understanding of interpersonal relationships (11 questions), problem-solving initiative (8 questions), and system thinking (20 questions) were used. Satisfaction with the program was investigated, and a self-reflection essay was written. For the analysis, paired t-test, frequency analysis, and content analysis were used. Results: After participating in the program, interpersonal understanding, proactivity in problem-solving, and systems thinking all significantly improved (p<.001), and the effect size of the program was also above medium (Cohen’s d= 0.580∼1.019). As a result of analyzing the contents of the self-reflection journal, it was classified into 7 themes and 3 categories; Teamwork competency, systems thinking skills, interpersonal skills. Students were generally satisfied with the program. Conclusion: The simulation game-based teamwork program was effective in improving students’ teamwork. These results can be used as basic data for medical schools designing such programs.
종설 : 새로이 개발되어 사용되기 시작하는 당뇨병 관련약제
박이병 ( Ie Byung Park ) 대한내과학회 2007 대한내과학회지 Vol.72 No.5
Recent advances in understanding insulin secretion, action and signaling have led to the development of new pharmacological agents. Several new emerging drugs and drug classes for the management of diabetes are under development, including the incretin mimetic agents (exenatide, dipeptidyl peptidase 4 inhibitors, and glucagon-like peptide 1 analogues), the amylin analogue pramlintide, the cannabinoid-1 receptor antagonist rimonabant, the mixed peroxisome proliferator-activated receptor agonists muraglitazar and the inhaled insulin preparation Exubera. New drugs and technologic advances being made available will help achieve the goals of treating patients with diabetes to all the appropriate metabolic targets. Longer term studies will help providers weigh the benefits, adverse effects, cost, and unknown long-term risks of these medications. (Korean J Med 72:446-450, 2007)
한국 성인에서 혈중 C 형 간염 바이러스 항체의 발현율과 의의
권소영(So Young Kwon),박이병(Ie Byung Park),박상훈(Sang Hoon Park),연종은(Jong Eun Yeon),박영태(Young Tae Bak),김진호(Jin Ho Kim),변관수(Kwan Soo Byun),이창홍(Chang Hong Lee),윤도경(Do Kyoung Yoon),조경환(Kyung Hwang Cho) 대한내과학회 1995 대한내과학회지 Vol.48 No.3
N/A Objectives : The prevalence of anti-HCV among blood donors is about 0.3 to 1.5% when assessed by first or second generation EIA. The significance of anti-HCV in a low risk population such as blood donors is unclear, To estimate the prevalence and significance of anti- HCV (second generation EIA) in Korean adults, we tested 4-RIBA and HCV-RNA RT-PCR in the sera of anti-HCV positive cases with normal serum ALT level. Methods : Serum samples from 5707 adults who visited Health Counseling Center were tested for ALT, HBsAg and anti-HCV by second genration EIA (UBI). Anti-HCV positive cases with normal serum ALT participated in a brief questionnaire and serum samples of them were tested for HCV by a 4-RIBA and HCV-RNA by RT-PCR. Results: The overall prevalence of anti-HCV among Korean adults is 1.77% and among adults with normal serum ALT is 1,45%. History of prior blood transfusion was more frequent in anti-HCV positive cases than anti- HCV negative cases. In 28 anti-HCV positive cases with normal serum ALT level, 4-RIBA was reactive in 35.7% and HCV- RNA was detected in 39.3%. HCV-RNA was detected in 9 of 10 4-RIBA reactive cases but in only 2 of 18 indeterminate or nonreactive cases. All 9 cases with sample/cut-off ratio of greater than 5 in anti-HCV EIA were 4-RIBA reactive and contained HCV-RNA, but only 2 of 19 cases with sample/cut off ratio less than 5 contained HCV-RNA. Conclusion: The overall prevalence of anti-HCV among Korean adults is 1,77%. About 40% of anti-HCV positive cases with normal sALT level contained serum HCV-RNA by RT-PCR. Reactive results of 4-RIBA and high sample/cut-off ratio in anti-HCV EIA correlated well with detection of HCV-RNA by RT-PCR.
장결핵의 감별진단에 있어서 3 개월 추적 대장내시경 검사의 의의
연종은(Jong Eun Youn),박이병(Ie Byung Park),권소영(So Yung Kwon),김재선(Jae Seon Kim),변관수(Kwan Soo Byun),박영태(Young Tae Bak),김종극(Jong Guk Kim),이창홍(Chang Hong Lee),김진호(Jin Ho Kim) 대한내과학회 1996 대한내과학회지 Vol.50 No.2
N/A Objectives: A therapeutic trial with antituberculous drugs is reasonable if the clinical and colonoscopic features are compatible, in countries with a high prevalence of intestinal tuberculosis. But Crohn's disease, lymphoma and other infectious disease should be differentiated from the disease. There have been no established monitoring modalities to assess the efficacy of the therapeutic trial and to differentiate these diseases yet. Therefore, this study was done to assess the usefulness of follow-up colonoscopy at 3 months of antituberculous treatment as a monitoring modality. Methods: 42 patients with tentative diagnosis of intestinal tuberculosis which was made on the basis of clinical and colonoscopic findings were enrolled, The patients were divided into 2 groups according to the symptomatic improvement after the therapy : (A) 30 patients with improved symptom : (B) 12 patients with persistent symptom. Colonoscopy with biopsy was performed before and at 3 months of therapeutic trial. Standard four-drug antituberculous chemotherapy was done at least for 9 months and patients were followed for more than a year after completion of therapy. Final diagnoses were made on the basis of satisfactory outcome of therapeutic trial, operative findings and another follow-up colonoscopy. Results: 1) colonscopic findings at 3 months of therapy improved in 31 cases. 27 of them were finally diagnosed as tuberculosis, 1 was as ulcerative colitis and 3 were lost. Among 11 endoscopically unimproved cases, 7 were finally diagnosed as Crohn's disease, 2 were as tuberculosis and 2 were lost. 2) 27 of 29 patients with final diagnosis of intestinal tuberculosis improved colonoscopically at 3 months of therapy. 2 unimproved cases had a complicated disease(stenosis) or an atypical mycobacterial infection, respectively. 3) In group A, 1 was diagnosed as ulcerative colitis and in group H, 3 were diagnosed as tuberculosis finally. Conclusion: Follow-up colonoscopy at 3 months of antituberculous therapeutic trial in patients with tentative diagnosis of intestinal tuberculosis seems to be a valuable modality for monitoring the efficacy of therapy and differentiating intestinal tuberculosis from other diseases.
우리나라 당뇨병의 역학적 규모와 당뇨병 관리현황 파악을 위한 표본설계의 평가
이지성,김재용,백세현,박이병,이준영,Lee, Ji-Sung,Kim, Jai-Yong,Baik, Sei-Hyun,Park, Ie-Byung,Lee, June-Young 대한예방의학회 2009 예방의학회지 Vol.42 No.2
Objectives : An appropriate sampling strategy for estimating an epidemiologic volume of diabetes has been evaluated through a simulation. Methods : We analyzed about 250 million medical insurance claims data submitted to the Health Insurance Review & Assessment Service with diabetes as principal or subsequent diagnoses, more than or equal to once per year, in 2003. The database was re-constructed to a 'patient-hospital profile' that had 3,676,164 cases, and then to a 'patient profile' that consisted of 2,412,082 observations. The patient profile data was then used to test the validity of a proposed sampling frame and methods of sampling to develop diabetic-related epidemiologic indices. Results : Simulation study showed that a use of a stratified two-stage cluster sampling design with a total sample size of 4,000 will provide an estimate of 57.04%(95% prediction range, 49.83 - 64.24%) for a treatment prescription rate of diabetes. The proposed sampling design consists, at first, stratifying the area of the nation into "metropolitan/city/county" and the types of hospital into "tertiary/secondary/primary/clinic" with a proportion of 5:10:10:75. Hospitals were then randomly selected within the strata as a primary sampling unit, followed by a random selection of patients within the hospitals as a secondly sampling unit. The difference between the estimate and the parameter value was projected to be less than 0.3%. Conclusions : The sampling scheme proposed will be applied to a subsequent nationwide field survey not only for estimating the epidemiologic volume of diabetes but also for assessing the present status of nationwide diabetes control.
인천광역시 의원기반 건강포인트제도가 고혈압,당뇨병 환자의 지속치료에 미치는 영향
정원 ( Won Cheong ),임준 ( Jun Yim ),오대규 ( Dae Kyu Oh ),임정수 ( Jeong Soo Im ),고광필 ( Kwang Pil Ko ),박이병 ( Ie Byung Park ) 한국보건행정학회 2013 보건행정학회지 Vol.23 No.4
Background: This study was conducted to evaluate the factors affecting adherence in patients with hypertension and type 2 diabetes mellitus before and after a clinic based patient incentive program in Incheon. Methods: An observational follow-up study was done for 28,355 patients in one registered group and 245,598 patients in a non-registered group from March 16th 2009 to December 31th 2010 in Incheon. The registration, mandatory laboratory tests and number of clinic visits were collected by merging the Incheon Chronic Disease Management System data and the National Health Insurance Corporation (NHIC) data. As a measure of patient adherence, we used a variable of prescription days from the NHIC and defined above 80% of average prescription days as an appropriate patient adherence. Repeated measures analysis of variance and logistic regression were used to analyze the differences in patient adherence and factors affecting adherence. Results: The changes in prescription days for the registered group are larger than for the non-registered group. In the logistic regression model, including the variables with sex, age, income status and number of clinic visits, the registered group exhibited a higher Odds ratio in the patient adherence. Conclusion: This study revealed the association between registration and appropriate patient adherence in patients with hypertension or type 2 diabetes mellitus.
서울 남서부 지역 남자 노인 인구에서 음주 , 흡연과 혈압 및 혈중 지질 농도와의 연관성
최경묵(Kyung Mook Choi),김경오(Kyung Oh Kim),조영직(Young Jik Cho),김동림(Dong Rim Kim),김난희(Nan Hee Kim),박이병(Ie Byung Park),백세현(Sei Hyun Baik),최동섭(Dong Seop Choi) 대한내과학회 2001 대한내과학회지 Vol.60 No.6
N/A Background : It is known that the effects of cigarette smoking and alcohol consumption on cardiovascular disease are very diverse. We investigated the effects of cigarette smoking and alcohol consumption on cardiovascular risk factors such as hypertension and dyslipidemia in male elderly living in Seoul, Korea. Methods : We examined the relationship of smoking and alcohol consumption to cardiovascular risk factors in 236 Korean men aged over 60 years in the community-based cross-sectional study from August 1999 to October 1999. Results : Alcohol users had higher systolic blood pressure, HDL cholesterol and lower LDL cholesterol, total cholesterol compared with non-users. After adjustment with age, body mass index and amount of smoking, partial correlation analysis showed that amount of alcohol consumption positively correlated with systolic blood pressure (r=0.1479, p<0.05) and negatively correlated with LDL cholesterol (r=0.2704, p<0.01) and total cholesterol (r=0.1800, p<0.05). But smokers didn't show any difference of body mass index, blood pressure, and lipid profile compared with non-smokers. Conclusion : In Korean male elderly, alcohol consumption was associated with increased systolic blood pressure. Also alcohol consumption was confirmed to be associated with decreased LDL cholesterol and total cholesterol, which might have a protective effect on coronary heart disease. We couldn't find the correlation between blood pressure, lipid profile and cigarette smoking.(Korean J Med 60:521-528, 2001)