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증례 : 호흡기 ; 이물질 흡인과 관련된 기관지 방선균증 1예
노진규 ( Jin Kyu Noh ),정순희 ( Soon Hee Jung ),권우철 ( Woo Cheol Kwon ),이민수 ( Min Su Lee ),리원연 ( Won Yeon Lee ),신계철 ( Kye Chul Shin ),용석중 ( Suk Joong Yong ) 대한내과학회 2009 대한내과학회지 Vol.77 No.5S
기관지 방선균증은 드문 경우로 면역기능이 저하되거나 구강위생이 좋지 않은 경우 발생할 수 있다. 만성적인 경과를 보이기 때문에 진단이 늦어지고 폐암으로 오인되기도 한다. 원발성 기관지 방선균증은 매우 드문 사례로 기관지 방선균증이 의심될 때는 악성종양과 이물질 흡인을 고려하여야 한다. 본 증례는 기관지내시경을 시행하여 생선뼈로 판단되는 이물질과 육아조직을 제거하였으며 기관지세척을 통한 세포학적 검사에서 sulfur granule을 확인하여 기관지 방선균증을 진단하였다. Actinomycosis is a chronic suppurative infection that infiltrates mucosa associated tissues. Primary endobronchial actinomycosis is rare and very uncommon in association with a foreign body aspiration. We diagnosed endobronchial actinomycosis associated with a fish bone aspiration. The patient was a 55-year-old male with no history of hypertension, diabetes, or pulmonary tuberculosis. About 5 years ago, he had an episode of choking while eating fish, and had suffered a chronic cough and sputum since that episode. The patient underwent a fiberoptic bronchoscopy, and granulation tissue and foreign bodies were noted in the right lower bronchus. We diagnosed actinomycosis by the presence of sulfur granules in the bronchial wash cytology. We removed the foreign bodies, which were identified as fish bones, by rigid bronchoscopy. The patient was treated with intravenous antibiotics for 1 week and oral antibiotics for 5 weeks, and his symptoms resolved. Serial fiberoptic bronchoscopy documented a gradual resolution of the granulation tissue and inflammation. (Korean J Med 77:S1178-S1182, 2009)
이선녕 ( Shun Nyung Lee ),이석정 ( Seok Jeong Lee ),노진규 ( Jin Kyu Noh ),이민수 ( Min Su Lee ),이남석 ( Nam Seok Lee ),이부길 ( Bu Ghil Lee ),리원연 ( Won Yeon Lee ),용석중 ( Suk Joong Yong ),신계철 ( Kye Chul Shin ),김상하 ( Sa 대한천식알레르기학회 2008 천식 및 알레르기 Vol.28 No.4
Occupational allergic rhinitis caused by rabbit fur has been reported in Korea. However, occupational asthma due to rabbit fur has not yet reported in Korea. We report a suspected case of allergic asthma caused by rabbit fur on occupational exposure. A 35-year-old male developed dyspnea, chest discomfort related to rabbit fur. He has been worked for a spinning factory. He presented with a history of allergic rhinitis and asthma. Peripheral blood eosinophil count was 690/mm3. Bronchodilator response was positive, the results of skin prick test were positive for house dust mite, cockroach and rabbit fur. The level of specific IgE for rabbit fur was 8.39 KU/L. The methacholine challenge test was positive (PC20 1.96 mg/mL). These findings suggest that the rabbit fur could induce occupational asthma. We could not perform bronchoprovacation test with rabbit fur due to patient`s refusal. He is in a well controlled state with the use of a combination of inhaled corticosteroid and long acting β2 agonist after the avoidance of rabbit fur. (Korean J Asthma Allergy Clin Immunol 2008;28:309-312)