기계적 자극에 대한 백서 치주인대 섬유아세포의 변화

김태균,김창성,조규성,채중규,김종관,최성호,Kim, Tae-Gyun,Kim, Chang-Sung,Cho, Kyoo-Sung,Chai, Jung-Kiu,Kim, Chong-Kwan,Choi, Seong-Ho 대한치주과학회 2001 Journal of Periodontal & Implant Science Vol.31 No.2

Periodontal disease is characterized by inflammation and subsequent loss and/or damage to tooth-supporting tissues such as bone, cementum,and periodontal ligament. Periodontal ligament and cementum are the key tissues in the initial process of regeneration following periodontal disease. Therefore, studies on cementoblasts, which form cementum are emphasized. It is still unclear which cells cementoblast differentiate from. This study was conducted under the hypothesis that PDL fibroblast can differentiate into either cementoblast or osteoblast depending on the conditions of surrounding tissue. Clinically, with excessive traction force of orthodontic appliances or excessive occlusion hypercementosis is observed, and this has been confirmed histologically. Consequently, activation of cementoblast can be expected in rats when mechanical stimuli are given to PDL fibroblast. Therefore, the purpose of this article is to prove that PDL fibroblast differentiates into cementoblast in rats under mechanical stimuli using histologic and molecular methods. In this study, twenty rats were given hard diet. Ten of them were sacrificed after 1 week, and the others were sacrificed after two weeks. Slides were made from tooth specimen, and they were studied under the microscope. In addition, PDL fibroblast and cementum from the extracted teeth were analyzed with Northern blotting. In histologic examination, as time passed, PDL fibroblast migrated to the dentin side, differentiated into cementoblast, and formed new cementum. In Northern blotting, it was found that mRNA expression of cementoblast-specific proteins such as BSP, OC, OPN, and type I collagen were more prominent in rats sacrificed after 2 weeks of hard-diet than rats sacrificed after 1 week. From these findings we can conclude that PDL fibroblast can differentiate into cementoblast under mechanical stimuli. We think that 'Rat Models' used in this study will be beneficial to future studies regarding cementoblast.

수학사적 관점에서 오일러 및 베르누이 수와 리만 제타함수에 관한 탐구

김태균,장이채,Kim, Tae-Kyun,Jang, Lee-Chae 한국수학사학회 2007 Journal for history of mathematics Vol.20 No.4

베르누이가 처음으로 자연수 k에 대하여 합 $S_n(k)=\sum_{{\iota}=1}^n\;{\iota}^k$에 관한 공식들을 유도하는 방법을 발견하였다([4]). 그 이후, 리만 제타함수와 관련된 베르누이 수와 오일러 수에 관한 성질들이 연구되어왔다. 최근에 김태균은 $\mathbb{Z}_p$상에서 p-진 q-적분과 관련된 확장된 q-베르누이 수와 q-오일러 수, 연속된 q-정수의 멱수의 합에 관한 성질들을 밝혔다. 본 논문에서는 연속된 q-정수의 멱수의 합에 관한 역사적 배경과 발달과정을 고찰하고, 오일러 및 베르누이 수와 관련된 리만 제타함수가 해석적 함수로써 값을 가지는 문제를 q-확장된 부분의 이론으로 연구되어온 q-오일러 제타함수에 대해 체계적으로 논의한다. J. Bernoulli first discovered the method which one can produce those formulae for the sum $S_n(k)=\sum_{{\iota}=1}^n\;{\iota}^k$ for any natural numbers k. After then, there has been increasing interest in Bernoulli and Euler numbers associated with Riemann zeta functions. Recently, Kim have been studied extended q-Bernoulli numbers and q-Euler numbers associated with p-adic q-integral on $\mathbb{Z}_p$, and sums of powers of consecutive q-integers, etc. In this paper, we investigate for the historical background and evolution process of the sums of powers of consecutive q-integers and discuss for Euler zeta functions subjects which are studying related to these areas in the recent.

수종 생약재의 간염 B형 바이러스 증식 억제 활성 검색

김태균,한형미,강석연,정기경,김승희,Kim, Tae-Gyun,Han, Hyung-Mee,Kang, Seog-Youn,Jung, Ki-Kyung,Kim, Seung-Hee 한국생약학회 1999 생약학회지 Vol.30 No.3

This study was undertaken to test for anti-hepatitis B virus (HBV) activity of the aqueous extracts prepared from 9 medicinal plants of Korea (Cornus officinalis, Caesalpinia sappan, Rubus coreanus, Lycium chinense, Artemisia capillaris, Isatis tinctoria, Phyllanthus urinaria, Lysimachia christinae, Lonicera japonica). Aqueous extracts were tested for cytotoxicity and assayed for inhibition of HBV replication by measurement of HBV DNA and surface antigen (HBsAg) levels in the extracellular medium f HepG2 2.2.15 cells. The extract from Rubus coreanus, Artemisia capillaris, Phyllanthus urinaria decreased the levels of extracellular HBV virion DNA at concentrations ranging from 128 to $256\;{\mu}g/ml$ and inhibited the production fo HBsAg dose-dependently without showing cytotoxicity. Our findings suggest that these three hebal medicinal plants may have potential to develop as specific anti-HBV drugs in the future.

방재연구 - 기후변화를 고려한 시설별 방재기준 가이드라인 개발

김태균,Kim, Tae-Gyun 한국방재협회 2013 방재저널 Vol.15 No.4

동맥경화유발 토끼와 형질전환 마우스에서 산마늘 추출물의 항동맥경화 효과

김태균,김승희,강석연,정기경,최돈하,박용복,류종훈,한형미,Kim, Tae-Gyun,Kim, Seung-Hee,Kang, Soeg-Youn,Jung, Ki-Kyung,Choi, Don-Ha,Park, Yong-Bok,Ryu, Jong-Hoon,Han, Hyung-Mee 한국생약학회 2000 생약학회지 Vol.31 No.2

Atherosclerosis is emerging as one of the major causes of death in Korea as well as Western societies. In the present study; hypocholesterolemic and antiatherogenic effects of the ethanol extract of Allium victorialis Makino was investigated using the conventional rabbit and the cholesteryl ester transfer protein (CETP)-transgenic mouse model. Hypercholesterolemia was induced by feeding high cholesterol diet to the animals for 30 days and they were then fed with high cholesterol diet containing 0.5% of the A. victorialis extract for additional 30 (or 40) days. In the experiment using rabbits, treatment with the A. victorialis extract significantly decreased plasma total cholesterol, low density lipoprotein (LDL)-cholesterol, triglyceride levels and lipid peroxidation compared to those in the control group. Total cholesterol contents in the liver and the heart were also significantly decreased. Lipid staining of the aorta isolated from the rabbits showed that treatment with the A. victorialis extract decreased formation of atheromatous plaques on the intima of the aorta. In the experiment employing CETP transgenic mouse model, treatment with the A. victorialis extract decreased the levels of plasma total cholesterol and the tissue triglyceride levels in the heart. These results demonstrated that the ethanol extract of A. victorialis lowered serum cholesterol levels, tissue lipid contents and accumulation of cholesterol in the artery.

대규모 택지개발지구내 신교통시스템 도입효과 분석

김태균,장인석,이영훈,Kim, Tae-Gyun,Chang, In-Seok,Lee, Young-Hoon 한국토지주택공사 토지주택연구원 2010 LHI journal of land, housing, and urban affairs Vol.1 No.1

이 연구는 신도시 및 대규모 택지개발 지구내 신교통 시스템을 도입함으로써 예상되어지는 효과를 분석하고, 이에 대한 적용 가이드라인을 제시한 것이다. 이를 위해 각 신교통 시스템 및 유형별 복합카테고리를 설정하여 지역적 특성을 반영하고자 하였으며, 신교통 시스템 도입이 기존의 대중교통체계 및 간선도로를 대체함으로써 발생되어지는 사회적 편익을 산출하였다. 분석결과, 신교통시스템 도입은 교통혼잡비용 감소, 탄소저감, 각 지자체의 친환경적 정책 입안에 뚜렷하게 기여할 수 있는 것으로 밝혀졌다. 그러나 신교통시스템의 이러한 장점에도 불구하고 이 연구에서는 신교통시스템을 도입하고자 하는 지자체에서는 무엇보다도 지역여건에 부합하는 신교통 시스템 유형을 선별하는 것이 중요함을 강조하고 있다. 특히 지자체의 무분별한 신교통시스템 도입은 대규모 택지개발사업에 의한 분양가 상승으로 이어질 가능성이 매우 높기 때문이다. This study is evaluating that new hi-tech transit systems each type of function and introduce applicable guideline decreases land sale price in New town and Large scale land development projects. For this, use the look-up table through the composite category of each type of system at the functional types, local characteristics. It also, As introduce the new systems calculate the Social benefits such as altered public traffic transfer system, reduced transit time and reduced carbon emission considering the three-dimensional arterial roads. As a result, New transportation systems contribute that the more reducing traffic congestion and air pollution and municipalities seeks for environment-friendly policy. However, this paper emphasize that the new transportation system has been introduce without considering the characteristics of locality and the efficient arrangement of them, it cannot be transferred the to the existing public traffic efficiently, futhermore causes the sale price in new large scale land development projects.

하악과두의 골증식체 평가에 있어서 transmaxillary 촬영법과 transcranial 촬영법의 비교

김태균,김진수,Kim Tae Gyun,Kim Chin Soo 대한영상치의학회 1989 Imaging Science in Dentistry Vol.19 No.1

5개의 건조두개골의 하악과두에 인위적으로 골증식체를 형성한 후 수직각 25°, 수평각 0°를 부여한 transcranial 촬영법과 두부규격 방사선 촬영기를 이용한 transmaxillary 촬영법을 시행하여 얻은 90매의 transcranial 및 45매의 transmaxillary방사선사진을 통해 다음과 같은 결론을 얻었다. 1. transcranial 촬영법에서 골증식체가 하악과두의 상중부에 있을 때 폐구시에 관찰이 용이하였으나 (p<0.05), 그 이외의 부위에서는 통계학적인 유의성이 없었다(p>0.05). 2. 골증식체가 하악과두의 내부 및 중부 (p<0.05)에 위치하였을 때는 transmaxillary 촬영법에서 관찰이 더 용이하였으며 외부에 위치하였을 때는 통계학적인 유의성이 없었다 (p>0.05). 3. 골증식체가 하악과두의 상방(p<0.05) 및 후방(p<0.01.)에 위치하였을 때는 trans maxillary 촬영법에서 관찰이 더 용이하였으며 전방에 위치하였을 때는 통계학적인 유의성이 없었다. (p>0.05). 4. Transcranial 촬영법에서는 골증식체가 하악과두의 측방으로 위치할수록(p<0.01), transmaxillary 촬영법에서는 후방으로 위치할수록(p<0.35) 관찰이 용이하였다. The purpose of this study was to decide the diagnostic value of transmaxillary and transcranial projection in the evaluation of mandibular condyles. Five dry skulls with intact anatomic structure were selected for this study and the artificial osteophytes were attached to 9 different are as of the mandibular condyle. Ninety transcranial and forty-five transmaxillary radiographs were taken and then the radiographs were evaluated three times. The results were as follows; In transcranial radiographs, superocentral osteophyte was easily observed in closing state than in opening state (p<0.05). But there were no significant differences in other locations (p>0.05). The osteophytes on the medial and central portion easily observed at the transmaxillary projection than transcranial projection (p<0.05), but there was no significant difference on the lateral portion (p>0.05). The osteophytes on the superior (p<0.01) and posterior (p<0.01.) portion were easily observed at the transmaxillary projection than transcranial projection, but there was no significant difference on the anterior portion (p >0.05). The more laterally located osteophytes (p<0.01) at the transcranial projections were easily observed. The more posteriorly located osteophytes (p<0.05) at the transmaxillary projections were easily observed.

인중, 비익, 협골궁 협계대 및 Hamular Notch 간거리와 상악 전치 폭경에 관한 통계학적 연구

김태균,장완식,Kim, Tae-Gyun,Jang, Wan-Sik 대한치과보철학회 1983 대한치과보철학회지 Vol.21 No.1

A note on the values of Euler zeta functions at positive integers

김태균,J. Choi,Y. H. Kim 장전수학회 2012 Advanced Studies in Contemporary Mathematics Vol.22 No.1

Recently, Euler zeta function is introduced by [수식]In this paper, we consider the values of Euler zeta function at positive integers.

A visual proof : if e<A<B, then A^Be^B<B^Be^B

김태균,박진우 장전수학회 2022 Advanced Studies in Contemporary Mathematics Vol.32 No.3

In this paper, we give a visual proof of ABeB < eABB when e < A < B without word. Moreover, we obtained AB > BA when e < A < B which is the same result as Gallant’s but not different method.