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김병렬 한국로렌스학회 2008 D.H. 로렌스 연구 Vol.16 No.1
This paper reveals that many characters of Lawrence's literature commonly choose 1he process of 'involution,' and the essence of the ideology of Lawrence is to be reinterpreted in contemporary view with the involution that is interpreted in relation to Deleuze and Guattari's assertion of nomadic flight In the last edition, I had already discussed Mellors and Connie's involution from "Lady Chatterley's Lover" Therefore, I would like to examine the meaning of involution and flight from "Women in Love," a piece from his second literature era We can comprehend the core meaning of what the author seeks in involution by the involution of Ursula That is in accordance with Deleuze and Guattari's strategy of becoming- imperceptible in conclusion, I would like to reveal that the falsehood and deception, concealed with the magnificence that symbolizes the heights and depths of Hermione's pursuit, Paradoxically speaks for the value of involution that Ursula has chosen
PLLA/HA Composite Scaffold와 골수 줄기세포를 이용한 조직공학적 골재생에 대한 연구
김병렬,장현석,임재석,이의석,김동현,Kim, Byeong-Yol,Jang, Hyon-Seok,Rim, Jae-Suk,Lee, Eui-Seok,Kim, Dong-Hyun 대한악안면성형재건외과학회 2008 Maxillofacial Plastic Reconstructive Surgery Vol.30 No.4
Aim of the study: Scaffolds are crucial to tissue engineering/regeneration. Biodegradable polymer/ceramic composite scaffolds can overcome the limitations of conventional ceramic bone substitutes such as brittleness and difficulty in shaping. In this study, poly(L-lactide)/hydroxyapatite(PLLA/HA) composite scaffolds were fabricated for in vivo bone tissue engineering. Material & methods: In this study, PLLA/HA composite microspheres were prepared by double emulsion-solvent evaporation method, and were evaluated in vivo bone tissue engineering. Bone marrow mesenchymal stem cell from rat iliac crest was differentiated to osteoblast by adding osteogenic medium, and was mixed with PLLA/HA composite scaffold in fibrin gel and was injected immediately into rat cranial bone critical size defect(CSD:8mm in diameter). At 1. 2, 4, 8 weeks after implantation, histological analysis by H-E staining, histomorphometric analysis and radiolographic analysis were done. Results: BMP-2 loaded PLLA/HA composite scaffolds in fibrin gel delivered with osteoblasts differentiated from bone marrow mesenchymal stem cells showed rapid and much more bone regeneration in rat cranial bone defects than control group. Conclusion: This results suggest the feasibility and usefulness of this type of scaffold in bone tissue engineering.
알코올 전처치한 흰쥐에 Cyclohexane 투여가 Cytochrome P-450 dependent aniline hydroxylase 활성에 미치는 영향
김병렬,윤종국 한국환경보건학회 2003 한국환경보건학회지 Vol.29 No.2
To evaluate the effect of cyclohexane(CH) treatment on the liver cytochrome P-450 dependent aniline hydroxylase(CYPdAH) activity in alcohol-pretreated animals, CH(1.56 g/kg body weight) was intraperitoneally administered to Sprague-Dawley male rats, which had been drunk 15% alcohol in distilled water for 1,3 and 6 weeks. CH was injected to rats 4 times every other day and the animals were sacrificed at 24 hours after injection of CH. In the alcohol-pretreated rats, liver injuries were not demonstrated on the basis of the liver weight per body weight, the levels of serum alanine aminotransferase and hepatic microsomal glucose-6-phosphatase activities. By the CH treatment, alcohol-pretreated animals showed the significantly increased activity of hepatic microsomal CYPdAH. Concomitantly $V_{max}$ value in CYPdAH was more increased, whereas $K_{M}$ value more decreased in alcohol-pretreated animals by the treatment of CH. In conclusion, the increasing cause of microsomal CYPdAH in CH-treated rats pretreated with alcohol may be due to induction of enzyme protein in rat liver.r.r.