악성 흉수, 결핵성 흉수 및 부폐렴 삼출액과 농흉에서 Interferon-gamma, Interleukin-2 Receptor, Interleukin-6, Interleukin-10 농도의 비교

김명훈,김승준,박용근,김석찬,이숙영,김영균,김관형,문화식,송정섭,박성학,Kim, Myung-Hoon,Kim, Seung-Joon,Park, Yong-Keun,Kim, Seok-Chan,Lee, Sook-Young,Kim, Young-Kyoon,Kim, Kwan-Hyoung,Moon, Hwa-Sik,Song, Jeong-Sup,Park, Sung-Hak 대한결핵및호흡기학회 2000 Tuberculosis and Respiratory Diseases Vol.49 No.5

연구배경 : Cytokine은 주요한 염증 매개 물질로서 질환에 따라 다른 양상을 보일 수 있어, 흉수를 일으키는 다양한 원인 질환의 감별에 이용되어 왔다. 이 중에서 악성 흉수, 결핵성 흉수, 부폐렴 삼출액 및 농흉에서 INF-${\gamma}$, IL-2R, IL-6, IL-1를 동사에 측정하여 비교한 연구는 많지 않아 본 연구를 시행하게 되었다. 방법 : 흉수를 주소로 내원한 환자 중에서 흉수 천자로 삼출액이 확인된 환자들을 대상으로 흉수를 채취하여, ELISA kit를 이용하여 INF-${\gamma}$, IL-2R, IL-6, IL-10 농도를 측정하였다. 결과 : 악성 흉수, 결핵성 흉수, 부폐렴 삼출액 및 농흉에서 흉수 내의 cytokine의 순서대로, INF-${\gamma}$는 $16.7{\pm}50$, $295.5{\pm}585.5$, $10.0{\pm}0$ pg/ml, IL-2R은 $3247.4{\pm}1713.3$, $7423.5{\pm}3752.8$, $3790.2{\pm}3201.1$ pg/ml, IL-6는 $600{\pm}12.8$, $556.4{\pm}161.7$, $514.4{\pm}224.8$ pg/ml, IL-10은 $28.2{\pm}55.5$, $11.3{\pm}11.7$, $98.4{\pm}141.7$ pg/ml로 각각 측정되어, 결핵성 흉수가 다른 원인의 흉수에 비해 IL-2R 농도가 의 있게 높았으며, IFN-${\gamma}$ 농도도 높은 경향을 나타내었으며, 부폐렴 삼출액에서는 IL-10농도가 다른 원인의 흉수에 비해 의미있게 높았다. 결론 : 결론적으로 흉수 내의 IL-2R농도 측정은 결핵성 흉수와 다른 원인의 흉수를 감별하는데 어느 정도 도움이 될 것으로 사료되며, IL-10 측정은 부폐렴 삼출액과 다른 원인의 흉수를 감별하는데 어느 정도 도움을 줄 것으로 생각된다. Background : Cytokines are chemical mediators that control and modulate many inflammatory processes. They work in different fashions in a variety of diseases. Discriminating between malignant effusion, tuberculous effusion, and parapneumonic effusion are crucial from the clinical view-point in Korea. In the current study, interferon-gamma (IFN-${\gamma}$), soluble interleukin-2 receptor (IL-2R), interleukin-6 (IL-6) and interleukin-10 (IL-10) were measured for this purpose. Methods : Pleural fluids from patients with malignant disease, tuberculosis, parapneumonic effusion and lung empysema were collected and gauged using commercial ELISA kits. Results : 34 patients were enrolled in this study. Among these 15 cases were malignant effusions, 12 were tuberculosis pleurisy and 7 were parapneumonic effusion and lung empyema. The levels of cytokines measured in this study were as follows, in order of frequency, malignant effusion, tuberculous effusion, parapneumonic effusion and lung empyema. The levels of INF-${\gamma}$ were higher in tuberculous effusion than in malignant or parapneumonic effusion ($295.5{\pm}585.5$ vs. $16.7{\pm}50$ vs. $10.0{\pm}0$ pg/ml, p>0.05). The levels of IL-2R were higher in tuberculous effusion than in malignant or parapneumoruc effusion ($7423.5{\pm}3752.8$ vs. $3247.4{\pm}1713.3$ vs. $3790.2{\pm}3201.1$ pg/ml, p<0.05). No significant differences were found in the levels of IL-6 between the groups ($600{\pm}12.8$ pg/ml in malignant effusion, $556.4{\pm}161.7$ pg/ml in tuberculous effusion, $514.4{\pm}224.8$ pg/ml in parapneumoruc effusion). IL-10 levels were higher in parapneumoruc effusion than in malignant or tuberculous effusions ($98.4{\pm}141.7$ vs. $28.2{\pm}55.5$ vs. $11.3{\pm}11.7$ pg/ml, p<0.05). Conclusion : These results suggest that the measurement of IL-2R levels in pleural fluids may be a useful means of differentiating between tuberculous effusion and pleural effusions of other origins, and that the measurement of IL-10 levels in pleural fluids may be useful to differentiate between parapneumonic effusion and pleural effusions of other origins.

정상근과 근막 유발점이 활성화된 근육의 초음파 영상의 비교

김명훈,김수현,김현진,Kim, Myung-Hoon,Kim, Su-Hyon,Kim, Hyun-Jin 대한물리치료학회 2013 대한물리치료학회지 Vol.25 No.2

Purpose: The objective of this study was to offer primary clinical data examining whether change of imaging structure and quantitative evaluation of muscle activity on myofascial trigger points can lead to implementation of an analytical technique for evaluation of myofascial pain diagnoses. In addition, we examined the effect of a variety of mediation techniques, in order to examine neuromuscular physiological characteristics of myofascial trigger points muscle by comparing differences in pressure pain threshold and ultrasound imaging. Methods: Participants in the study included 30 adults in their twenties. The subjects were divided into the normal and myofascial trigger points groups. Clinical outcomes were evaluated by pressure pain threshold for pain and ultrasound imaging was performed for evaluation of the structural characteristics of muscle. Independent t-test was used for statistical analysis. Results: The two groups showed statistical significance in the change in pressure pain threshold (p<0.05). Findings of ultrasound imaging analysis showed no significant differences, increased muscle thickness was observed (p>0.05). Findings of ultrasound imaging analysis showed significant differences, increased muscle echodensity was observed (p<0.05). Findings on ultrasound imaging analysis showed significant differences, increased muscle white area index was observed (p<0.05). Conclusion: From these results, active myofascial trigger points muscle showed quality deterioration on ultrasound imaging. Thorough evaluation of imaging structure and physiological characteristics can be useful quantitative analytical techniques for diagnosis of myofascial pain syndrome and a primary factor reflected in physical therapy intervention.

효율적인 VOD 서비스를 위한 RVOD와 NVOD간의 전환 프로토콜

김명훈,박호현,Kim, Myoung-Hoon,Park, Ho-Hyun 한국정보처리학회 2008 정보처리학회논문지 A Vol.15 No.4

최근 광대역화 되어가는 네트워크 환경에 발맞춰 VOD의 수요 역시 급증하고 있다. 기존의 VOD 서비스는 RVOD 또는 NVOD 중 한 가지 방식으로만 서비스가 가능하였다. 이렇듯 한 가지 방식으로만 서비스를 하게 되면 시시각각 변화하는 클라이언트의 수요에 대응할 수 없어서 서버에 과부하가 걸리거나, 서버의 대역폭을 낭비하는 결과를 초래하는 등 서버의 네트워크 자원을 효율적으로 사용하지 못하였다. 이에 본 논문에서는 효율적인 VOD 서비스를 위한 프로토콜에 관한 연구를 수행하였다. 기존의 VOD 서비스 알고리듬을 적용할 수 있는 새로운 프로토콜을 제안하고, 시뮬레이션을 통해 성능을 분석하였으며, 새로운 프로토콜을 적용시킨 서버/클라이언트 구조의 시스템을 개발하였다. 본 논문에서는 RVOD/NVOD 통합 모드 전환 프로토콜을 제안한다. 제안된 프로토콜은 RVOD와 NVOD 두 가지 방식 모두를 제어할 수 있고, 두 방식간의 모드 전환을 할 수 있다. 그러므로 본 프로토콜을 사용하여 클라이언트의 수요 변화에 맞춰 모드를 전환한다면 서버의 대역폭을 효율적으로 관리할 수 있다. 특히 기존의 RVOD 및 NVOD 연구 방식들을 적용할 수 있다. 그러므로 본 논문에서 제시한 프로토콜은 앞으로의 VOD 시장에서 활용도가 매우 높을 것으로 기대된다. Recently, as network environment has broadened, the demands on VOD have been increased. The VOD services can be categorized into two types, RVOD and NVOD. Practical VOD services adopt one of them exclusively. Since a method using only one of RVOD and NVOD is not able to deal with frequently variable demand of clients, it leads to a result of overload on a server and a waste of server bandwidth. The efficiency of the network resource usage becomes lower. Hence this paper presents a study on the protocol for efficient VOD services. We propose a new protocol appliable for the existing VOD service algorithm, analyze its performance through simulation, and developed server/client systems applying the new protocol. We propose a mode switching protocol combined with protocols used in RVOD and NVOD. The proposed protocol is not able only to control both RVOD and NVOD but also to change the mode between RVOD and NVOD. As a result of using the proposed protocol to meet frequently variable demand, server bandwidth can be used efficiently. Especially, it can be applied to the existing VOD service algorithms. Therefore, we expect that the proposed protocol in this paper will be widely used in emerging VOD markets.

키네시오 테이핑과 발목관절 근력 운동이 균형지수에 미치는 변화

김명훈,이정훈,김찬규,Kim, Myung-Hoon,Lee, Jeong-Hun,Kim, Chan-Kyu 대한물리치료학회 2009 대한물리치료학회지 Vol.21 No.3

Purpose: This study examined that effect of a change in balance index on ankle Kinesio taping, muscle strength exercises and taping after muscle strength exercises in 30 healthy adult subjects. Methods: The Sway Index of the left, right, front and back on stable, toes up and linear were compared using a Balance System, a balance experimental instrument. Results: The pre and post experimental balance index regarding stable, toes up, and linear were taken for the Kinesio taping group, lower extremities muscle strengthening group, and muscle strengthening with the Kinesio taping group. Statistically significant decreases were observed in all variables except for the left and right pre and post experiment results under stable conditions. Conclusion: The balance index of exercise with taping was lower than that of exercise only. There is a need for objective research on the long-term applications and post-exercise. The body balance appears to be influenced by ankle stabilization using taping.

전자기록 환경에서의 기능평가 프로세스 분석

김명훈,Kim, Myoung-Hun 한국과학기술정보연구원 과학기술정보센터 2008 Journal of Information Science Theory and Practice Vol.39 No.4

본고에서는 기록물의 내용이 아닌 기록이 생성된 기능에 기반을 두고 행해지는 전자기록 환경에서의 기능평가 프로세스를 분석하였다. 전자기록 환경에서 기능평가는 가장 보편화된 평가방식으로, 기록물의 생산 이전단계부터 수행되는 연속적인 업무 프로세스를 형성하게 된다. 종국적으로 기능평가를 기반으로 하는 전자기록 환경에서의 평가는 업무맥락 및 기록품질을 지님과 동시에, 조직의 영위 및 업무 수행에 필수적인 전자기록을 선별해 주게 된다. This article minutely examines functional appraisal process that focuses on not content but function in which the records are created. Taking everything into consideration, functional appraisal in electronic record environments constitutes consecutive process that is performed organically in pre-creation stage of records. Ultimately functional appraisal in electronic record environments is organic process selecting electronic records across phases of whole record management, which assure business context and recordness, and need to run organization and perform business.

물리치료사의 직무만족과 이직의도에 관한 연구

김명훈,Kim, Myung-Hoon 대한물리치료과학회 2001 대한물리치료과학회지 Vol.8 No.1

This study was attempted to examine the relationship between job satisfaction and turnover intention of physical therapist in order to suggest some method to enhance their job performance and the degrees of job satisfaction. High turnover intention of physical therapist is one of the serious problems at the present time which providing low quality physical therapy. The data were collected from July 1, to August 31, 2000 and analyzed by ANOVA, Pearson Correlation Coefficients. The summarized result are as follows: 1. The job satisfaction score of physical therapists showed the highest of the pride of patient treatment and total mean score was 2.96. 2. Those who were in the range of 26 to 30 years of age showed the strongest desire to leave the hospital 3. There were 68.8% in male. 47.6% in female who hoped to turnover intention. 4. There were significant difference between those who want to leave and those who want remain in relation patient number, work hospital work years. 5. There were no significant difference between those who want to turnover intention and those who want remain in relation patient number and work years. 6. The major reason for job satisfaction were work time and work areas.

영국의 의료체계

김명훈,Kim, Myeong-Hun 대한병원협회 1993 대한병원협회지 Vol.22 No.1.2

FAU 제올라이트내에서 Ce (Ⅲ) 이온의 자리이동과 산화상태에 관한 형광 연구

김명훈,홍석봉,어용선 ( Myung Hun Kim,Suk Bong Hong,Young Sun Uh ) 한국화학공학회 1995 화학공학의이론과응용 Vol.1 No.2

레코드 컨티뉴엄과 평가, 그리고 기록콘텐츠 -기록콘텐츠 개념 정립을 위한 시론-

김명훈,Kim, Myoung-Hun 한국과학기술정보연구원 과학기술정보센터 2010 Journal of Information Science Theory and Practice Vol.41 No.3

본고에서는 레코드 컨티뉴엄 이론 속에 내재된 평가 논리를 기반으로, 전자기록 환경 속에서 기록이 지닌 의미 및 기록관리의 역할을 모색해 보고자 한다. 레코드 컨티뉴엄 이론에서 의도하는 평가 논리는 최근의 다원화 된 사회에서 기록의 의미 및 기록관리의 역할을 모색하는 데 유용한 이론적 기반을 제시해 줄 수 있다. 아울러 레코드 컨티뉴엄의 평가 논리를 통해 모색된 증거성을 지닌 가치 있는 기록의 의미 및 활용성 확대를 위한 방안으로 '기록콘텐츠'의 개념화를 시도하였다. This article intends to explore the meaning of record and role of record management in electronic record environments, based on appraisal theory of Records Continuum. Appraisal theory of Records Continuum can provide to explore the mean of record and role of record management in new social environment. And it try to build the Concept of archival contents for expanding the meaning and utilization of record based on appraisal theory of Records Continuum.

전자기록 환경에서의 세계 각국 평가체제 개편에 관한 연구 - 국가적 차원의 영구보존기록 평가전략을 중심으로 -

김명훈,Kim, Myoung-Hun 한국과학기술정보연구원 과학기술정보센터 2008 Journal of Information Science Theory and Practice Vol.39 No.2

본고는 전자기록 환경에서의 국가 평가체계 정비 방향을 모색하기 위한 시론적 연구로서의 의미를 지닌다. 전자기록 환경에서의 필연적인 평가방식이라 할 수 있는 기능평가는 국가적 차원의 영구보존 기록 선별에는 일정 한계를 지닌다. 이에 본고에서는 우선 기능평가가 지닌 한계를 논의한 다음, 이를 보완하기 위한 방안으로 영구보존 대상 평가전략의 필요성을 제기하였다. 그리고 이에 대한 구체적인 사례를 고찰하기 위해, 호주의 범정부 기능분석, 영구의 평가정책 및 수집정책, 독일의 다기관협력 평가전략, 캐나다의 거시평가 전략을 분석하였다. 결국 이러한 분석은 현용 가치와 사회적 가치가 조화된 국가 평가체계의 토대를 제공해주게 된다. This article intends to provide a direction for reconstructing the national regime of archival appraisal in electronic record environments. Functional appraisal, which inevitably carries out for appraising electronic records, has defects in aspect of selecting archives important in a national point of views. To do so, this article discusses defects of functional appraisal, and then suggests the necessity of archival appraisal strategies that complements functional appraisal. To investigate this archival appraisal strategies, it analyzes Australia's Whole-of-Government Functional Analysis, United Kingdom's Acquisition Policy and Appraisal Policy, Germany's Cooperative Cross-Archives Appraisal and Canada's Macro Appraisal. Ultimately, this analysis is able to establish a base of the regime of archival appraisal which will harmonize primary value at current stage with secondary value at non-current stage in a national point of views.