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만성 기침으로 내원한 환자에서 원인 질환 및 빈도에 관한 전향적 연구
지영구,오형태,이계영,김건열,조상헌,민경업,김유영 (Young Koo Jee,Hyung Tae Oh,Kye Young Lee,Keun Yeol Kim,Sang Heon Cho,Kyung Up Min,You Young Kim) 대한천식알레르기학회 1998 천식 및 알레르기 Vol.18 No.2
Background: Chronic cough is commonly defined as a persistent or recurrent cough exceeding 3 weeks duration and the prevalence of chronic cough is reported to range from 14-23% among non-smoking adults. Irwin et al previously reported that common causes of chronic cough are postnasal drip syndrome asthma, and gastroesophageal reflux using the anatomic and diagnostic protocol. Objective: To determine the spectrum and frequency of chronic cough and to aid establishing algorithmic approach for chronic cough. Materials and metkod: We prospectively evaluated 105 consecutive and unselected immunocompetent patients complaining of chronic cough utilizing modified anatomic and diagnostic protocol proposed by Irwin et al. Initial diagnosis was made by history, physical examination and laboratory test including spirometry, methacholine provocation test, and 24 hour pH monitoring. Specific treatment was done based upon initial diagnosis and cough score was compared before and after treatment. Reassessment was done in case of treatment failure. Resalt: The causes of cough were determined in 100 of 105 patients(95% ). Cough was due to one condition in 94.8% and two in 15.2%. 121 causes of cough were identified and their spectrum and frequency were found to be postnasal drip syndrome (39.3% ), asthma (32.2% ), gasteroesophageal reflux (14.1%), chronic bronchitis (5.0%), others (4.1%: drug-induced, bronchiolitis, endobronchial tuberculosis, and lung cancer). History about nasal symptoms was useful, but history about gastroesophageal reflux were not useful for the diagnosis. Conclusion: The results suggest that anatomic and diagnostic approach for evaluating chronic cough is also useful in Korea and the most common causes of chronic cough are postnasal drip syndrome, asthma and gastroesophageal reflux.
이재호(Jae Ho Lee),현인규(In Gyu Hyun),최동철(Dong Chul Choi),유철규(Chul Gyu Yu),송재훈(Jae Hoon Song),정기석(Ki Suck Jung),김영환(Young Whan Kim),한성구(Sung Ku Han),심영수(Young Soo Shim),김건열(Keun Yeol Kim),한용철(Yong Chul Han 대한내과학회 1991 대한내과학회지 Vol.40 No.3
N/A Radiation pneumonitis is one of the most important early complication of radiation therapy. In order to examine whether or not the increasing in patients suffering from concurrent COPD and Lung Ca, and to study clinical features of radiation pneumonitis, the writers conducted a retrospective study on 60 patients with proven lung cancer who underwent radiation therapy during the period from 1985 to 1988 and had their PFT performed before the radiation and obtained the following results; 1) Non productive cough was the most frequent clinical symptom of radiation pneumonitis and dyspnea, whitish sputum, chest tightness, mild fever was also present. The clinical symptom was not related to radiation dose, initial time of pneumonitis, PFT, age but was more serious in the patients with FEV1/FVC more than 70%. 2) Radiation pneumonitis occurred most frequently between the period of 4 weeks and 12 weeks and onset time of radiation pneumonitis was not related to the radiation dose, PFT, age, 3) Chest X-ray showed alveolar, alveolar-interstitial mixed, interstitial pattern, fibrosis confined to radiation field and changed with time. 4) There was no significant difference between FEV1, FVC, FEV1/FVC and incidence of radiation pneumonitis but in patents with FEV1/FVC more then 70%, there was significantly higher incidence of radiation pneumonitis. 5) The incidence of radiation pneumonitis was increased as radiation dose was increased.