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RISS 인기검색어
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- 저자 : 권굉보(Kyung Bo Kwun) (검색결과 4 건)
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간절제후의 IL-1β , IL-6 및 TNF-α의 변화
김홍진 ( Hong Jin Kim ),심민철 ( Min Chul Shim ),윤성수 ( Sung Su Yun ),전용성 ( Yong Sung Jeon ),권굉보 ( Kyung Bo Kwun ) 대한소화기학회 1997 대한소화기학회지 Vol.29 No.2
N/A Background/Aims: The liver is a central organ in metabolic and irnmune homeostasis under normal and pathologic condition and its funtion is directed by classic homiones and a network of cytokine mediators. Because the liver has a strong potentiol for regeneration, clarifying its mechanism is a matter of great interest. Although many studies on cytokines are being conducted, its clinical significance in hepatectomy still remains unclear. The aim of this study is to clarify the changes of serum cytokines and to investigate the possible regulation of the cytokine release in hepatectomy. Methods: We studied 55 patients who had underwent hepatectomy in the department of surgery at Yeungnam University Hospital between Septernber 1992 and July 1994. Serum levels of IL-1 0, IL-6, TNF- a were measured before operation and on the postoperative day(POD) 1, 3, 5 and 7. Then those were compared between patients with major resection(more than 2 segments) and minor resection, between patients with cirrhosis and those without cirrhosis, and between patients with recovered without complication and patients recovered with comp]ication or inortality. Results: ln the recovery group, the levels of serum IL-10 reached peak levels at POD # 1 and then gradually decreased, the levels of the serum IL-6 reached peak levels at POD 0 l and re- elevated at POD # 5, but there was no significant change in the serial levels of the serum TNF- a. No significant difference in the serial levels of cytokines(IL-] 0, IL-6, TNF- a ) was found hetween the patients with cirrhosis and those without cirrhosis and between the major resection and minor resection. The levels of cytokines in the complication R mortality group were higher than those of the recovery group. Conclusions; The levels of IL-I 3, IL-6 reached peak level at POD # 1 and gradually decreased to normal levels at POD 0 7 in the recovery group. In the complication & mortality group, the levels of cytokines were higher than those of the recovery group. (Korean J Gastroenterol 1997;29:192-198)
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간세포암에서 경동맥문맥조영중 전산화단층촬영 100예의 의의
이헌주(Heon Ju Lee),김홍진(Hong Jin Kim),장재천(Jae Chun Chang),박복환(Bok Hwan Park),조재호(Jae Ho Cho),한건수(Kon Soo Han),심민철(Min Cheol Shim),권굉보(Kyung Bo Kwun),김태년(Tae Nyon Kim),정문관(Mun Kwan Jung) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.5
N/A We retrogradely analized the meannings of computed tomography during arterial portography (CTAP) compared with conventionally contrast enhanced computed tomography (conventional contrast CT) taken in 100 cases of hepatocellular carcinoma. We could find 57.8% additional borderline. lesions with CTAP in number of patients and 92.5% in numbers of masses. Portal vein invasion which was not demonstrated by conventional contrast CT could be detected by CTAP in 10 cases. In diagnosis of unilatral or bilateral lobe involvement for determinantion of treatment planning, CTAP could prevent 35.5% of mis-underdiagnosis of unilateral lobe involvement by demonstrating the nodule and/or portal vein invasion cf controlateral lobe. In conclusion, CTAP is very usefuI in detection of hidden borderline lesion, portal vein invasion, and recognition of portal venous flow nature in preserved portion of liver. Therefore CTAP is considered essential in pretreatment evaluation of hepatocellular carcinoma for determination of proper treatment principles.
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조길호,정경희,황미수,장재천,권굉보,민현식 영남대학교 의과대학 1985 Yeungnam University Journal of Medicine Vol.2 No.1
1983년 5월부터 1985년 11월까지 영남대학교 의과대학 부속병원에서 복부농양을 의심하여 초음파검사를 시행후 확진된 48명의 환자에서 초음파소견을 분석하여 다음과 같은 결과를 얻었다. 1)농양의 위치는 복강내 농양이 30예, 내장 농양이 13예, 후복막강농양이 5예였다. 2)원인별로는 복강내 농양의 25예는 충수돌기염에 의하였고, 5예는 수술후 합병증으로 생겼다. 후복막강농양 5예는 전부 요근농양으로, 결핵성 및 화농성이 각각 2예, 후복막강에 위치한 충수돌기 염증이 1예였다. 내장농양은 12예가 간농양으로 이 중 9예는 화농성, 3예는 아메바성이었고 췌장염에 의한 췌장미부농양이 1예였다. 3)형태는 총 48예중 26예(54%)에서 구형 또는 난원형이었으며, 특히 내장농양이 복강내 농양에 비해 구형 또는 난원형이 많았다. 4)병변의 크기는 26예(54%)에서 5∼10㎝사이였으며, 내부echo는 33예(69%)에서 낭포성이었다. Intraabdominal abscess usually causes distress with fever, leukocytosis, pain and toxicity. Diagnosis of intraabdominal abscess is occasionally difficult and it has high morbidity. However radiologic method, such as ultrasonography, CT scan, or RI scan are helpful to early detection of intraabdominal abscess. Among these methods, ultrasonography is a non-invasive technique and performed without discomfort to patient. And also differential diagnosis between cystic and solid lesion is very easy and sequential ultrasonography in same patient is valuable for the evaluation of treatment effect. We analyzed the ultrasonic features of 48 cases with intra-abdominal abscesses and the results are as follows; 1.In total 48 cases, the intra-abdominal abscesses were 30 cases, the retroperitoneal abscesses, 5 cases, and the visceral abscesses, 13 cases. 2.The causes of the intra-abdominal abscesses were perforating appendicitis (25 cases), postoperative complications (5 cases), pyogenic and amebic hepatic abscesses(13 cases), and the others(5 cases). 3.Round or oval shaped lesions were 26 cases(54%), irregular shape, 18cases (38%), and multiple abscess formation in 4 cases(8%). 4.The size of the lesions were between 5 and 10㎝ in diameter in 54% of total 48 cases, and the most frequent feature of the echo-pattern of the lesions was cystic with or without internal echogenicity(69%).
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