316 스테인리스강의 크리프 성질에 미치는 재결정 발생의 영향

고광진,유연철,이만천 대한금속재료학회(대한금속학회) 1987 대한금속·재료학회지 Vol.25 No.3

Constant-stress creep tests at temperatures of 913,953 and 993 K over a stress range of 140 to 230 MPa were made on AISI 316 stainless steel to investigate the effect of recrystallization occurring during creep. The best creep properties were obtained in the specimens which had been pre-stained 207% arid tested at 953 K under a stress in the range of 147-170 MPa. Above 30% pre-strain the creep properties gradually deteriorated, which was attributed to partial recrystallization. The carbides in the partially recrystallized specimens,0.1-0.3㎛ large, did not coalesce during creep but remained dispersed in the grains and grain-boundaries. In the 30% pre-strained condition, the best creep properties were obtained with the creep stress of 200-230 MPa at 953k. The creep resistance was considerably reduced by 40% pre-strain. It was responsible for the coarsening of carbides and the formation of subgrains.

Predictive factors of prolonged warm ischemic time (≥30 minutes) during partial nephrectomy under pneumoperitoneum

고광진,최돈경,신승제,유현수,김태선,송완,전황균,정병창,서성일 대한비뇨의학회 2015 Investigative and Clinical Urology Vol.56 No.11

Purpose: Current clinical data support a safe warm ischemia time (WIT) limit of 30 minutes during laparoscopic partial nephrectomy (LPN) or robot-assisted partial nephrectomy (RPN). We evaluated independent factors predicting prolonged WIT (more than 30 minutes) after LPN or RPN. Materials and Methods: A retrospective data review was performed for 317 consecutive patients who underwent LPN or RPN performed by the same surgeon from October 2007 to May 2013. Patients were divided into two groups: group A was defined as prolonged WIT (≥30 minutes) and group B as short WIT (<30 minutes). We compared clinical factors between the two groups to evaluate predictors of prolonged WIT. Results: Among 317 consecutive patients, 80 were in the prolonged WIT group. Baseline characteristics were not significantly different between the groups. In the univariable analysis, PADUA (preoperative aspects and dimensions used for an anatomical) score (p=0.001), approach method (transperitoneal or retroperitoneal approach; p<0.001), and surgeon experience (p<0.001) were significantly associated with prolonged WIT. In the multivariable analysis, PADUA score (p=0.032), tumor size (≥25 mm; odds ratio, 2.98; 95% confidence interval, 1.48-5.96; p=0.002), and surgeon experience (p<0.001) were independent predictors of prolonged WIT. Conclusions: Surgeon experience, tumor size, and PADUA score predicted prolonged WIT after RPN or LPN. Among these factors, increasing surgical experience with LPN or RPN is the most important factor for preventing prolonged WIT.

Robotic Sacrocolpopexy for Treatment of Apical Compartment Prolapse

고광진,이규성 대한배뇨장애요실금학회 2020 International Neurourology Journal Vol.24 No.2

Abdominal sacrocolpopexy is the gold-standard treatment for apical compartment prolapse, as it is more effective and durable than the transvaginal approach. In the current era of minimally invasive surgery, laparoscopic sacrocolpopexy techniques have been described, but have not gained popularity due to their complexity and steep learning curves. To overcome this problem, robotic sacrocolpopexy was introduced, and has shown equivalent outcomes and safety compared to open and laparoscopic sacrocolpopexy based on findings that have been accumulated over 15 years.

라인 레이저의 산란에 강인한 심도 측정 방법

고광진,연승호,김재민 한국멀티미디어학회 2018 멀티미디어학회논문지 Vol.21 No.2

Line-laser beams are used for depth measurement of welding beads along the circumference of a pipe. For this, first we project a line-laser beam on an rotating pipe and take a sequence of images of the beam projected on the pipe using a CCD camera. Second, the projected line laser beam in each image is detected, converted into a thin curve. Finally measure the distance between the thinned curve and an imaginary line. When a line-laser beam is projected to a rough metal surface such as arc welding beads, the beam is severely scattered. This severe scattering makes the thinned curve perturbed. In this paper, we propose a thinning method robust against scattering of line lasers. First, we extract a projected line laser beam region using an adaptive threshold. Second, we model a thinned curve with a spline curve with control points. Next, we adjust the control points to fit the curve to the projected line-laser beam. Finally, we take a weighted mean of thin curves on a sequence of image frames. Experiments shows that the proposed thinning method results in a thinning curve, which is smooth and fit to the projected line-laser beam with small error.

반응 표면 분석에 의한 생강 분말을 첨가한 쌀 압출 성형물의 이화학적 성질

고광진 한국식품영양학회 1993 韓國食品營養學會誌 Vol.6 No.3

본 연구에서는 단축 스크류 압출성형기를 이용하여 생강분말을 첨가한 쌀가루를 압출성형시켰을 때 일어나는 이화학적 성질 변화 반응표면 실험계획법에 의하여 분석하였다. 생강가루를 첨가한 쌀 압출성형물의 일반성분의 변화는 생강분말의 첨가량이 증가할수록 가용성 무질소물의 함량은 감소하는 반면 조지방, 조단백질, 조회분 조섬유 함량은 증가하였다. 2가지 독립변수인 생강함량(0∼12%)과 수분?량(14∼26%)의 주어진 범위에서 각 종속변수인 이화학적 성질에 대하여 3차원 반응표면 회귀분석하였을 때, 팽화율은 수분함량에 따라서는 변곡점(critical point)을 형성하면서 생강함량 4.30%, 수분함량 18.37%일 때 최적반응을 나타내었는데 이때 팽화율의 최적추정치는 1.83이었으며, 밀도와 전단강도는 수분함량과 생강함량이 교호적으로 증가함에 따라 증가의 폭이 커짐을 알 수 있었다. 또한 수분함량과 생강함량이 많아지면서 수분흡수 지수는 증가하였고, 수분 용해도 지수는 감소하였다. 호화도는 생강함량 6.15%, 수분함량 15.56%일 때 최대점을 나타내어 이때의 최적추정치는 88.27%이었고, 명암도는 생강함량이 증가할수록 반대로 감소함을 나타내었다. 한편, 화상분석기를 이용하여 관찰한 미세구조를 2가지 독립변수인 생강함량과 수분함량의 주어진 범위에서 3차원 반응표면 회귀분석한 결과, 최적반응을 보였을 때 각 요인들의 임계치는 생강함량 4.62%, 수분함량 19.57%로 단위 면적당 기공수의 최적 추정치는 94.88개이고, 생강함량 4.76%, 수분함량 17.97%일 때 기공 총둘레에 대한 최적 추정치는 2546.48㎛로 안부점(saddle point)을 형성하였다. 그리고 생강함량 2.79%, 수분함량 19.03%일 때 기공 총면적과 기공의 화적율에 대한 최적 추정치는 각각 512370㎛^2, 76.16%이었고, 생강함량이 증가하면서 기공의 총면적과 화적율은 증가하면서 수분함량에 따라서는 변곡점을 형성하였다. 이상의 결과를 종합하여 볼 때, 생강가루와 쌀가루를 혼합하여 제조한 extrudate의 품질은 토출구 온도 110℃에서 쌀가루에 생강분말 2∼7%를 섞어 수분함량 15∼20%로 조정하여 압출 팽화할 때 우수하였다. This research was attempted to investigate changes in physicochemical properties of rice extrudate with added ginger powder extruded by single screw extruder. Graphic three dimensional analysis on response surface regression was used to evaluate effects of extrusion variables on quality factors of the extrudate according to two independent variables, ginger content 0∼12%, moisture content 14∼26%. The summarized results are as follows: 1) Regarding proximate composition of rice extrudate with added ginger powder, as ginger powder content of raw material increased, crude fat, crude protein, crude ash and crude fiber increased, while soluble nitrogen free extract decreased. 2) Graphic three dimensional analysis on response surface regression was conducted for each dependent variable which revealed statistically significant relationship with independent variables, 0∼12% ginger and 14∼26% moisture content. Expansion ratio had a critical point as moisture content changed. As ginger and moisture content increased, bulk density, break strength and water absorption index increased, while water solubility index decreased. The predicted maximum degree of gelatinization in 6.15% ginger and 15.56% moisture content is 88.27%, and lightness decreased as ginger content increased. According to the microstructure for the cross section of extrudate obsorbed with image analyzer, air cell number and perimeter revealed saddle point, meanwhile total area and fractarea of air cell had critical points as moisture content changed. In view of the results, quality of rice extrudate with added ginger powder was optimum when rice flour was fed to the extruder with 2∼7% ginger powder and 15∼20% moisture content.

소비자들저가품 선호가 품질저하 -생산업체 난립, 덤핑 판매 초래-

고광진 한국식품산업협회 1989 좋은식품 Vol.100 No.-

Current surgical management of pelvic organ prolapse: Strategies for the improvement of surgical outcomes

고광진,이규성 대한비뇨의학회 2019 Investigative and Clinical Urology Vol.60 No.6

There are a variety of surgical management strategies to help surgeons repair pelvic organ prolapse (POP). Surgical treatment for POP includes native tissue repair, augmentation with mesh, and minimally invasive surgeries. Currently, laparoscopic or robotic techniques for POP repair are increasing in popularity and continuing to evolve. The aim of this review is to present an up-to-date review of surgical techniques used for POP repair and to discuss ways to optimize surgical outcomes.

A Prospective Observational Study of the Recurrence Characteristics of Hunner Lesion After Repeated Transurethral Ablation in Patients With Interstitial Cystitis/Bladder Pain Syndrome

고광진,변혜진,방석환,이규성 대한배뇨장애요실금학회 2022 International Neurourology Journal Vol.26 No.3

Purpose: The aim of this study was to investigate the rate and pattern of recurrence for patients with Hunner lesion (HL) type interstitial cystitis/bladder pain syndrome (IC/BPS) after transurethral ablation. Methods: This prospective study included 210 patients with HL type IC/BPS. The primary outcomes were the recurrence rate according to 3 patterns of recurrence: pattern A (according to the relationship with the previous surgical site), pattern B (according to the bladder zone), and pattern C (according to the number of lesions). The secondary outcomes were recurrencefree time after treatment according to pattern A and pattern C. Results: The pattern A recurrence rate was 50.8% in the same site (A1), 6.7% at a new site (A2), and 42.5% at mixed sites (A3). The pattern B recurrence rate was 10.5% for the anterior wall, 59.0% for the posterior wall, 69.5% for the lateral wall, and 69.0% for the dome area. Multiple lesions recurred as multiple lesions in 75.8% of cases. The pattern C recurrence rate was 10.8% for C1 (single → single), 6.7% for C2 (single → multiple), 6.7% for C3 (multiple → single), and 75.8% for C4 (multiple → multiple). The recurrence-free time in pattern A was 13 months for A1, 12.5 months for A2, and 8 months for A3, with a significant difference between A1 and A3 (P=0.008). There was no significant difference in recurrence-free time in pattern C, either with single or multiple HLs. Conclusions: The distinct recurrence characteristics of HLs was not predictable despite repeated ablations. Complete remission should not be expected because the whole bladder was to have the potential to develop the HLs even after repeated transurethral ablation.

A Korean Postmarketing Study Assessing the Effectiveness of OnabotulinumtoxinA for the Treatment of Neurogenic Detrusor Overactivity or Idiopathic Overactive Bladder Using a Validated Patient-Reported Outcome Measure

고광진,Brenda Jenkins,Anand Patel,이규성 대한배뇨장애요실금학회 2019 International Neurourology Journal Vol.23 No.1

Purpose: OnabotulinumtoxinA has demonstrated efficacy and safety in the treatment of urinary incontinence (UI) associated with neurogenic detrusor overactivity (NDO) and idiopathic overactive bladder (OAB); however, real-world evidence is limited. This postmarketing surveillance study aimed to assess the effectiveness and safety of onabotulinumtoxinA in Korean patients with UI associated with NDO or OAB with an inadequate response or intolerance to anticholinergics. Methods: Patients received 200 U (NDO) or 100 U (OAB) of onabotulinumtoxinA. Effectiveness (assessed using the validated International Consultation on Incontinence Questionnaire-Short Form [ICIQ-SF]) and safety were assessed for 1–4 months after onabotulinumtoxinA administration. Results: Overall, 686 patients (NDO, 161; OAB, 525) comprised the safety population; of these, 612 patients were analyzed for effectiveness. There was a significant decrease (P<0.0001) in the mean (standard deviation) ICIQ-SF scores in the NDO (–6.8±5.5) and OAB (–6.0±6.4) groups after onabotulinumtoxinA administration. A decrease of >5 points from baseline in the ICIQ-SF score was observed in 64.9% and 47.3% of patients in the NDO and OAB groups, respectively. Following treatment, 59.9% in the NDO group and 43.0% in the OAB group were dry. There was no effect of age on effectiveness in either group. Only 10 adverse drug reactions (ADRs) were reported in 5.6% of NDO patients and 20 ADRs in 3.2% of OAB patients. Most ADRs in both groups were related to the lower urinary tract such as dysuria (NDO, 1.2%; OAB, 0.6%) and urinary retention (NDO, 0.6%; OAB, 1.5%). Conclusions: Effectiveness and safety of onabotulinumtoxinA in Korea in a real-world setting was demonstrated.

A Multicenter, Open-Label, Observational Study Evaluating the Quality of Life After Using a Hydrophilic-Coated Catheter (SpeediCath) With Self-Intermittent Catheterization

고광진,주명수,김선옥,김장환,정경진,유은상,김명기,조원진,최종보,이지환,이규성 대한배뇨장애요실금학회 2022 International Neurourology Journal Vol.26 No.4

Purpose: We evaluated the change in patient quality of life after the use of a hydrophilic-coated catheter (SpeediCath) in adults requiring intermittent catheterization (IC). Methods: This was a multicenter, open-label, observational study using the Patient Perception of Intermittent Catheterization (PPIC) questionnaire and the Intermittent Self-Catheterization questionnaire (ISC-Q) and safety at 12 and 24 weeks in adult patients who had already used other type of catheters prior to switching to SpeediCath or in patients undergoing self-IC for the first time for any reason. Results: Among a total of 360 subjects, 215 (59.7%) were women, and the mean age was 62.0±13.2 years. At 24 weeks, the satisfaction rate after using SpeediCath was 84.1%, and 80% of patients responded that they could easily perform IC. In total, 81.6% of patients were willing to continue using SpeediCath. The mean ISC-Q score was 54.90±18.65 at 24 weeks. Men found less interference in their daily life by performing IC than women and found it easier to handle the catheter before it was inserted into the urethra. At week 12, the mean change in ISC-Q was significantly greater in patients <65 years (20.24±23.55) than in those ≥65 years (7.57±27.70, P=0.049), but there was no difference at 24 weeks. The most common adverse events were urinary tract infection in 9.72%, gross hematuria in 2.78%, and urethral pain in 1.39%. Conclusions: The use of a SpeediCath provided good quality of life for patients who needed self-IC regardless of age or sex.