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서순봉,전재복 대한피부과학회 1974 大韓皮膚科學會誌 Vol.12 No.1
Clinical observations were made on 251 cases of pyodermas at the Department of Dermatology, Kyungpook University Hospital from 1968 to 1972. Especially noteworthy is the application of josamycin to 41 cases of pyodermas to observe its therapeutic effects. Since 1968, the frequency of pyodermas has shown an annual increase. The ratio between male and female was 1. 4: 1, gradually changing from 2. 3: 1 in 1968 to an almost balanced incidence in 1972. The age of onset. differed with types of disease, but 76. 2% of all cases occurred before the age of 15. The outbreaks of impetigo bullosa and impetigo vulgaris were found to be affected by season, the highest prevalence being in summer. Seasonal occurrence of all cases was found to be 45.5%o in summer and 24. 3% in fall with no noticeable change ohserved in spring and winter. Predilection sites of the disease differed according to the type of the disease but all types showed a marked predilection for the exposed areas as against the covered areas (4 times). Sensitivity of causative organisms to antibiotics was found to be fairly high to cloxacillin, novobiocin and ampicillin, and relative to kanamycin, streptomycin and doxycycline but all tested cases showed resistance to tetracycline, chlortetracycline and oxytetracycline. Josamycin was effective in all types of pyodermas, and was dramtical]y so in impetigo bullosa of which pustules disappeared within 3 or 5 days of treatment. Two out of 41 cases complained of abdominal pain and weakness. The sensitivity of the causative organisms of all types of pyodermas to josamycin was 83. 3%.
두부백석 (頭部白癬) 에 대한 Hairbrush 배양법의 일변법 (一變法) 에 관하여
서순봉,김희교 대한피부과학회 1965 大韓皮膚科學會誌 Vol.4 No.1
In isolating the causative organisms of dermatophytosis, the callection of pathognomic materials, the culture methods, and the condition of media are known to be the most important factors concerning the positive rate for identification of fungal infections of the skin. There have been many reports and suggestions for the improvement of media, however, the collection of pathognomic materials and the culture methods were geaerally neglected. In 1963, Mackenzie reported, that he had a favorable results in obtaining higher numbers of isolates by using his hair brush method in tinea capitis due to Trichophyton tonsurans, and Rosenthal and Wapnick succeeded also in obtaining the higher isolates of Trichophyton mentagrophytes by using self-made hair brush from clinically normal guineapigs. Facing with thc complexity of past favored epilating hair culture method, authors intended to suggest a variant of the method using two self-made brushes, the one is the various test tube washing brushes with shortcut hairs and the other brushes resembling tooth brushes. Brushes putready for use after sterilization and whenever patients come, the materials had been collected applying the brushes to the lesions by rotating several times and then cultured by touching several times to the slope of media, the brushes were applied sufficient force to dislodge some hairs and scales, but not hard enough to break the surface of the agar. The followings are the results of comparative studies between the epilating hair culture method and the variant brushing culture method applied to 86 cases of tinea capitis. 1 Higher numbers of diseased hair including scales were obtained by the variant brushing method, as compared with epilating hair culture method which used to affored diseased hair only 2. Of 36 cases of tinea capitis examined, 32 cases yielded positive culture while 30 cases were isolated by epilating hair culture method. 3. Lesser contaminations were noted. 4. The variant brushing culture method is more easier and spare time in handling. 5. The brushes applied to the lesion could be preserved for repeat cultures. 6. The brushes were easily available and inexpensive. 7. The variant brushing culture method yielded more apparent colonies in color, and the colonies were abundant in number.