지표수에서 이산화염소 및 염소 복합소독에 의한 트리할로메탄 생성 평가

남숙현,김은주,구재욱,황태문 한국수처리학회 2022 한국수처리학회지 Vol.30 No.6

Due to its synergistic effects, sequential disinfection is considered a viable treatment option for the effective inactivation of pathogenic microorganisms that cannot be treated using the single-step application of chlorine-based disinfectants. This study systematically demonstrated the applicability of sequential disinfection with chlorine dioxide followed by chlorine to control disinfection byproducts. At pH 7,chlorine dioxide/chlorine treatment suppressed the formation of trihalomethanes (THMs) by 10.0% and 25.0% at temperatures of 10℃ and 20℃, respectively, compared to chlorine only. In addition, when using chlorine oxide/chlorine disinfection, a higher pH led to amore significant suppression of THMs production. It was also found that THMs production was lower as the chlorine dioxide dosage increased; in particular, the use of 1.2 mg/L and 5.0 mg/L chlorine dioxide at pH 9 had a substantial suppressive effect on THMs formation, with a reduction of 25.8% compared to chlorine only. Higher temperatures and a higher dissolved organic carbon concentration suppressed the generation of THMs in the chlorine dioxide/chlorine disinfection system compared with the chlorination alone. .

자외선/염소 산화기술에 의한 Microcystin-LR 제거 특성

남숙현,이주원,김은주,구재욱,황태문 한국수처리학회 2019 한국수처리학회지 Vol.27 No.4

Cyanobacteria blooms in waters have become a worldwide issue for drinking water production. Microcystin-LR (MC-LR), a toxic compound produced by cyanobacteria, is very toxic and poses a threat to public health. The World Health Organization has proposed a provisional guideline concentration of no more than 1.0 ㎍/L for MC-LR in drinking water. In conventional water treatment, chlorination is applied for the elimination of MC-LR, but when the influent pH is higher than 8.0, a higher chlorine dose is required, which may increase disinfection by-products. In this study, low pressure UV/chlorine oxidation precess has been evaluated for effective removal of MC-LR. MC-LR with an initial concentration of 100 ㎍/L was reduced by about 90 % under the condition of a chlorine concentration of 1.0 ㎎/L and UV dose of 200 mJ/㎠ which was much higher than 50 % removal under UV process alone and 60 % removal under chlorination alone. In UV/chlorine oxidation process, reactive chemical species such as OH radicals and chlorine radicals were involved, showing synergistic efficient than UV and chlorination alone process. These results shows the UV/chlorine is one of the effective oxidation process for MC-LR elimination.

장기간의 무용프로그램이 지역아동센터 아동들의 기초체력과 자아존중감 및 주의집중력에 미치는 영향

남숙현,류호상 한국무용학회 2017 한국무용학회지 Vol.17 No.3

The purpose of this study was to investigate the effects of chronic dance program on basic physical fitness (strength, endurance, flexibility, balance, power, agility), self-esteem (overall, social, at home, in school), and concentration (cognition function) in children. A total of thirty subjects in a local children center were randomly assigned to one of two groups, experimental (n=15) or control (n=15) group. The experimental group participated in the dance program which was scheduled for 12 weeks, two times a week, and sixty-minutes for each session. The data obtained from each measure were analyzed using Analysis of Covariance, respectively. The results of data analysis showed that the experimental group performed significantly better in the strength, the flexibility, the balance, the overall self-esteem and the self-esteem at school, and the concentration compared to those of the control group. It was concluded that the participation of 12 weeks of dance program can improve basic physical fitness, self-esteem, and cognition function in children. 본 연구는 장기간의 무용프로그램 참여가 아동들의 기초체력(근력, 지구력, 유연성, 평형성, 순발력, 민첩성)과 자아존중감(총체적, 사회적, 가정에서의, 학교에서의 자아존중감) 및 주의집중력에 미치는 영향을 알아보는 것이었다. 연구 참여에 동의한 총 30명의 지역아동센터 아동들은 실험집단(n=15) 또는 통제집단(n=15)에 무선(random)으로 할당되었다. 실험집단은 12주 동안, 주 2회, 회당 60분을 지속하는 무용프로그램에 참여하였다. 두 집단의 평균값 비교를 위해 SPSS WIN Version 22.0K 프로그램을 이용하여 사전검사 값을 공변인으로 하는 공분산분석(Analysis of Covariance)을 실시하여 다음의 결과들을 도출하였다. 첫째, 실험집단의 아동들은 통제집단의 아동들에 비해 근력, 유연성, 평형성이 더 높은 것으로 나타났다. 둘째, 실험집단의 아동들은 통제집단의 아동들에 비해 총체적 자아존중감과 학교에서의 자아존중감이 더 높았다. 셋째, 실험집단의 아동들은 통제집단의 아동들에 비해 주의집중력이 더 높았다. 따라서 12주간 무용프로그램은 지역아동센터 아동들의 기초체력과 자아존중감 및 인지기능에 긍정적인 영향을 미칠 수 있다는 결론에 도달하였다.

폐수방류수 오존처리시 오존 및 OH 라디칼 노출량 기반 미량유기오염물질 제거 예측

남숙현,황태문,김은주,신용현,이광희,김유곤,이윤호 한국수처리학회 2022 한국수처리학회지 Vol.30 No.4

Municipal wastewater is a major source of contaminants of emerging concern in aquatic environments. Many studies have proven the effectiveness of ozonation for the removal of micropollutants, though the composition of the wastewater matrix influences the oxidation potential during this process. The ozone decomposition rate consists of two stages: instantaneous ozone consumption and slower ozone decay. In particular, with instantaneous ozone consumption, 62.8-79.7% of the initial ozone injection concentration is consumed. Determining the appropriate ozone dosage for wastewater ozonation is complicated by the complexity of the wastewater matrix composition. The purpose of this study was to propose a chemical kinetic model for the prediction of micropollutant removal during the ozonation of wastewater effluent. A kinetics approach based on the measurement of ozone and hydroxyl radical(·OH) exposure was proposed to predict the micropollutant removal efficiency. In this study, a batch-type ozone reactor was set up to measure the ozone and OH radical exposure during wastewater ozonation. Ozone and OH radical exposure was proportional to the initial dose of ozone, while OH radical exposure was found to be proportional to ozone exposure, though the deviation was relatively high at 1.0 to 1.5 gO3/gDOC. The calculated OH radical exposure was 3.0×10-10 to 5.3×10-10M·s. Of the target micropollutants, acetaminophen, sulphamethoxazole, andnaproxen, which are highly reactive with ozone and OH radicals, exhibited a removal rate of more than 80% at an ozone injection rate of 0.75 gO3/gDOC. .

인체 생리기능의 계절적 변동에 관한 연구

남숙현 고려대학교 의과대학 1973 고려대 의대 잡지 Vol.10 No.2

This experimental was carried out to investigate the existence or absence of adaptation to seasonal changes exhibited by men living in temperate climates for period of one year. The percentage of total body fat were calculated from skinfold thickness and urinary 17-ketosteroid excretion were measured by Rapaport's method every season for the same subject in 60 healthy Koreans, Skinfold thichness at five sites, namely, back waist arm, abdomen and knee were measured by means of a Lange caliper. The findings obtained were as follows; 1. The course of increase in total body fat was identical to that of body growth from spring to winter season in a teen-agers of between 10 and 14 years. The mean total fat for one year were 17.4% of body weight in boys and 23.8% in girls. 2. Total body fat showed a decrease in a twenties, namely, 13.3% in male and 23.0% in female. subject. 3. In a thirties, the total body fat was predominantly increased to 26% of body weight, while negligible in male. 4. The skinfold thickness on all sites were greater in females than males at the same age. Although they showed different pattern. 5. Seasonal fluctuation has been observed in total body fat and subcutaneous fat thickness after twenties, rising during winter and early spring falling in the summer. 6. The regional differences of the subcutaneous fat thickness was greater in male than that of female. neater in male 7. Urinary 17-ketosteroid excreation showed a continuous increase in absolute value as age increased, and falling in the summer in male. while any demonstrable changes in female. Theories concerning the mechanism of the adaptation to seasonal changes were reviewed for the purpose of explanation of the results obtained. From the above findings, it may be speculated that seasonal fluctuation of fat and cortical hormone is an adaptation to cold, the increased fat providing extra thermal insulation. but it might also be related to the pattern of activity and food intake in excess of energy expenditure.

GABA가 동통자극에 대한 흑질 뉴론의 반응에 미치는 영향

남숙현,이배환 고려대학교 의과대학 1990 고려대 의대 잡지 Vol.27 No.2

The present study was conducted to determine what GABAergic receptor IS involved in substantia nigra(SN) pain modulation mechanism. After the spontaneous activity of SN neurons was recorded, the responses of neurons to noxious peripheral stimulation and to iontophoretically applied GABA, SR95531, baclofen, and naloxone were observed. Results are as follows : 1. GABA inhibited the activities of S N neurons responding to noxious stimulation. 2. SR95531 increased the spontaneous activities of SN neurons and disinhibited the effect of GABA. 3. Baclofen had little effect on the activities SN neurons. 4. Naloxone tended to inhibit neuronal activities but did not correspond to effects of GABAergic drugs. These results suggest that GABAA receptor is involved in SN pain modulation mechanism mediated by GABA and this mechanism is not identical to opiate system.

인체 생리기능의 계절적 변동에 관한 연구

남숙현 고려대학교 의과대학 1973 고려대학교 의과대학 잡지 Vol.10 No.2

각종 Benzene 및 Phenol계 물질이 담즙 배설에 미치는 영향

남숙현 우석대학교 의과대학 1970 우석의대잡지 Vol.7 No.2

The effect of 2,4-dinitrophenol and its chemically related compounds on biliary secretion were investigated in the anesthetized dogs. The results are summarized as follows; 1. All compounds possessing Phenol-rings tested in this experiment with exception of amino Phenol produced a marked increase in bile flow with concomitant decrease in concentration of chelate. Of these compounds, 2,4-dinitrophenol was the most potent in increasing the bile flow, picric acid in contrast, was the least potent. 2. The compounds possessing benzene-ring also produced the increase in bile flow. However their potency was somewhat lower than that of compounds possessing phenol-ring, among these compounds, chlorbenzene was the most potent agent in increasing bile flow. From the above findings, it is suggested that to produce the increase in bile flow by these compounds it is necessary to have two nitro groups on the same molecule and they have to be in positions 2 and 4 on the benzene-ring.

도서지역 가뭄 대응을 위한 지하저류조 및 분리막 기술 활용 사례

남숙현,구재욱,신용현,김은주,황태문 한국막학회 2023 한국막학회 총회 및 학술발표회 Vol.2023 No.11

가토(家兎)의 간장(肝臟) 및 신장(腎臟)에서의 색소분필(色素分泌) 과정(過程)에 관(關)하여

남숙현,Nahm, Sook-Hyun 대한생리학회 1971 대한생리학회지 Vol.5 No.2

That different mechanisms are involved in the secretory processes by the liver and the kidney of various dyes has been indicated by Sporter (1959), Kim and Hong (1963). Andrews (1958). suggested that a striking difference in the dye-secretory mechanism existed even in the same organ from species to species. Hence, the attempt has been made to study in the rabbit the secretory processes by the live. and the kidney of either phenol red (PSP), bromsulfalein (BSP) or green in the presence of Na-acetate, Na-taurocholate, P-Aminohippurate (PAH) or Benemid. In 37 rabbits, weighing about 2kg., anesthetized with ether, a dye was administered in such 8 manner that the plasma concentration was kept at a relatively constant level throughout the whole experimental period. Hepatic bile sad urine samples were quantitatively collected through the canulae which were previously inserted into the common bile duct (with the cystic duct ligated) and the urinary bladder, respectively, while arterial samples were taken from a femoral artery. After 50 min from the onset of dye administration, these samples were obtained every 10 mit for a period of 40 min. This was followed by the administration of either Na-acetate, Na-tauro-cholate, PAH or Benemid with a repetition of the same sample collecting procedures just stated. The results may be summarized as follows: 1) Na·acetate augmented urinary clearance of PSP by nearly 300 per cent, but lowered urinary BSP clearance by about 50 per cent. It enhanced biliary BSP clearance by 40% and had no effect on biliary psp clearance. 2) Na-taurocholate lowered biliary and urinary clearance of PSP by 10 per cent and 30 per cent respectively, and had no effect on both biliary and urinary clearance of BSP. 3) PAH lowered both biliary and urinary excretion of BSP and PSP, while it lowered the biliary excretion of indocyanine green which was excreted only in the bile. 4) Benemid suppressed BSP excretion by the liver and the kidney. 5) raper chromatographic analysis of PSP and of BSP in the bile and urine samples gave the following results: a) PSP Ivas excreted in the urine and bile only in free forms, and no modification in the excretory pattern was brought about by Na-taurocholate. b) BSP was excreted in the urine in 4 different conjugated froms and in the bile in both 3 different conjugated forms and in a free form. Na-taurocholate modified the excretory pattern of the urinary BSP.