Microfluidic generation of Prussian blue-laden magnetic micro-adsorbents for cesium removal

Kang, Sung-Min,Rethinasabapathy, Muruganantham,Hwang, Seung Kuy,Lee, Go-Woon,Jang, Sung-Chan,Kwak, Cheol Hwan,Choe, Sang-Rak,Huh, Yun Suk Elsevier 2018 CHEMICAL ENGINEERING JOURNAL -LAUSANNE- Vol.341 No.-

<P><B>Abstract</B></P> <P>Here, we designed and synthesized a recoverable multifunctional adsorbent using a microfluidic reaction system and evaluated the removal performance of the smart adsorbent toward radioactive cesium as a model sample. Prussian blue-laden magnetic micro-adsorbents (PB-MNPs-MAs) with uniform morphology and monodispersity were generated via two-step sequential procedures using a glass capillary microfluidic system, followed by chemical co-precipitation with a high production rate. The cesium removal efficacy of the PB-MNPs-MAs was analyzed based on Langmuir and Freundlich isotherms by controlling adsorption parameters such as adsorbent size, initial cesium concentration, and contact time. The adsorption isotherm of the PB-MNPs-MAs was better fitted to the Langmuir model with a maximum cesium adsorption capacity of 58.73 mg g<SUP>−1</SUP>, which was 40% higher than that of macro-adsorbents in a dynamic magnetic field. This result can be attributed to their large specific area, which increased the kinetic rate of cesium adsorption and achieved saturation within 20 min. Additionally, the PB-MNPs-MAs were recovered from wastewater within 5 s under a static magnetic field, indicating their great potential for magnetic actuation. We believe that our PB-MNPs-MAs can encapsulate nano-functional adsorbents and prevent actuation, making them promising for environmental remediation and especially for removal of radionuclides.</P> <P><B>Highlights</B></P> <P> <UL> <LI> PB-MNPs-MAs were generated in microfluidic device using chemical co-precipitation. </LI> <LI> The prepared PB-MNPs-MAs are monodispersed with uniform morphology. </LI> <LI> PB-MNPs-MAs exhibited high Cs adsorption capacity (58.73 mg g<SUP>−1</SUP>). </LI> <LI> 100% recovery of PB-MNPs-MAs is possible under static magnetic field after Cs adsorption. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Antibacterial Effect and Deodorization Effect of Extracts from Different Parts of Zingiber officinale

Young Suk Lee,Young Ju Kang,Min Jeong Ryu 한국피부과학연구원 2020 아시안뷰티화장품학술지 Vol.18 No.4

목적: 생강 부위별 추출물의 피부 상재균에 대한 항균효과 및 암모니아에 대하 소취능을 평가하여 항균소재 및 기능성 향장품 소재 로서의 가능성을 예측하고자 한다. 방법: 피부 상재균에 대한 항균효과는 paper disc 방법으로 측정하였다. 소취효과 측정은 암모 니아 가스 제거 실험을 하였다. 결과: 생강 부위별(잎, 줄기, 뿌리) 추출물 항균효과 측정 결과 S. aureus에 대한 항균효과는 5 mg/ mL 농도에서 각각 3 mm, 3 mm, 2 mm의 clear zone이 확인되었다. S. epidermidis에 대한 항균효과는 각각 8 mm, 5 mm, 4 mm 의 clear zone이 확인되었다. 여드름의 원인균인 P. acnes에서는 각각 4 mm, 3 mm, 1 mm의 clear zone이 확인되었다. P. ovale에 서는 각각 6 mm, 5 mm, 4 mm의 clear zone이 확인되었다. M. furfur에서는 각각 4 mm, 3 mm, 2 mm의 clear zone이 확인되었다. C. albicans에서는 각각 4 mm, 3 mm, 2 mm의 clear zone이 확인되었다. 마지막으로 T. mentagrophytes에 대한 항균효과를 측정 한 결과 5 mg/mL 농도에서 생강 잎 추출물은 6 mm, 줄기 추출물은 4 mm, 뿌리 추출물은 3 mm의 clear zone이 확인되었다. 암모 니아에 대한 소취효과를 측정한 결과 120 min에는 생강 잎 추출물은 98%, 줄기 추출물은 95%, 뿌리 추출물은 91%의 소취효과가 확인되었다. 결론: 생강 부위별 추출물 중 잎 추출물이 7종의 피부상재균에 대한 항균효과도 가장 우수하였으며, 소취효과도 생강 잎 추출물이 가장 높은 효과가 확인되어 항균소재 및 기능성 향장품 소재로서의 가능성을 확인하였다. Purpose: Using extracts from different parts of Zingiber officinale , we aimed to evaluate its antibacterial effect on skin flora and its deodorization effect on ammonia to determine its potential as an antimicrobial ingredient and functional herbal cosmetic ingredient. Methods: The antibacterial effect on skin flora was examined using the paper disc method and the deodorization effect on ammonia was examined by the gas detection method. Results: After evaluating the antibacterial effects of extracts from different parts (leaves, stems, and roots) of Zingiber officinale , antibacterial activity was observed against Staphylococcus aureus (S. aureus ) at a concentration of 5 mg/mL. The leaf, stem, and root extracts had 3 mm, 3 mm, and 2mm clear zones, respectively. For the antibacterial effect against Staphylococcus epidermidis (S. epidermidis ), there were 8 mm, 5 mm, and 4mm clear zones for the leaf, stem, and root extracts, respectively. For Propionibacterium acnes (P. acnes ), a bacterium that causes acne, there were 4 mm, 3 mm, and 1mm clear zones for the leaf, stem, and root extracts, respectively. The results for Pityrosporum ovale (P. ovale ) showed 6 mm, 5 mm, and 4 mm clear zones for the leaf, stem, and root extracts, respectively. For Malassezia furfur (M. furfu ), there were 4 mm, 3 mm, and 2 mm clear zones for the leaf, stem, and root extract, respectively. For Candida albicans (C. albicans ), there were 4 mm, 3 mm, and 2mm clear zones for the leaf, stem, and root extracts, respectively. Finally, after evaluating the antibacterial effect against Trichophyton mentagrophytes (T. mentagrophytes ) at a concentration of 5 mg/mL, we found 6 mm, 4 mm, and 3 mm clear zones for the leaf, stem, and root extracts, respectively. After evaluating the deodorization effects of Zingiber officinale extracts on ammonia, at 120 min, the deodorization effect was 98%, 95%, and 91% for the leaf, stem, and root extracts, respectively. Conclusion: Among the three extracts of Zingiber officinale , the leaf extract had the highest antibacterial effect against the seven types of skin flora as well as the highest deodorization effect, thus confirming its potential as an antibacterial ingredient and functional herbal cosmetic ingredient.

종이접기에 의한 정다각형의 작도

강신민,김석룡 慶尙大學校 1990 論文集 Vol.29 No.1

In classical constuctions the exercise uses a straight edge and a pair of compasses. As in Paper-foldings are not used them, it is impossible to describe a circle or other curves. However, we can receive easily several important geometic processes, to divide straight lines and angles into two or more equal parts to draw perpendiculars and parallels to straight lines. In this paper, I'll make again how to make regular polygons(regular 3-gon, 4-gon, 5-gon, 6-gon, 8-gon, 10-gon, 12-gon) while are confined in some degree by Paper-foldings and make regular 8-gon, 12-gon among them with other method. Finally, I will put the point in making a regular 9-gon which is impossible with a straight edge and a pair of compasses by using any angle into three sections in Paper-foldings and I will explain the course that Paper-foldings maks any angle into three sections which is impossible with only a straight edge and a pair of compasses possible.

우울증 환자에 대한 Amineptine Hydrochloride의 임상 효과

강민희,신석철,왕성근,신윤오 최신의학사 1990 最新醫學 Vol.33 No.7

Culex pipiens pallens의 난황단백질 합성에 관한 연구

강석희,박영민,조정래,문정희 성균관대학교 기초과학연구소 1987 論文集 Vol.38 No.2

Anautogenous한 모기인 한국산 집모기 Culex pipiens pallens의 난황단백질 합성에 대한 hormone 들의 효과를 조사하였다. 피를 먹지않는 c. pipines 암모기의 head extract를 decapitation한 Aedes atropalpus에게 주사하였을 때 난성숙이 재유발되었으며, 난성숙의 재유발 정도는 우화 후 주사시기가 지연될수록 증가하여 우화 후 24시간에 주사하였을 때 최고에 도달하였다. 피먹은 C. pipiens를 흡혈 즉시 decapitation 또는 abdominal ligation하여도 난성숙이 저지되지 않았다. 이러한 결과는 C. pipiens의 brain hormone은 헙혈 즉시 방축되기 시작하여 난성숙의 시작을 자극하는 것으로 여겨진다. 피를 먹지않은 C. pipiens 암모기에게 β-ecdysone을 주사하거나 또는 head extract 주사 후 JHI을 처리하였을 때 fat body가 합성하는 vitellogenin의 양이 증가하였다. The effect of brain hormone, Juvenile hormone and β-ecdysone on the synthesis of vitellogenin in the anautogenous mosquito, Culex pipiens pallens, has been examined. Head extract from non-blood fed C. pipiens females, when injected into the decapitated Aedes atropalpus females, stimulated egg maturation. The ovarian development in C. pipiens was not completely blocked by decapitation or abdominal ligation performed immediately following a blood feeding. These results suggested that the release of brain hormone in this mosquito may be triggered by a feeding activity. Injection of β-ecdysone or head extract followed by topical application of JH into non-blood fed C. pipiens females stimulated vitellogenin synthesis. These results supported the previous work in Aedes aegypti that brain hormone, JH and ecdysone, in that sequence, are required for the egg maturation.

인공 생명 기법을 이용한 로봇 군 지능 구현

민석기,강훈 중앙대학교 생산공학연구소 1998 생산공학연구소 논문집 Vol.7 No.1

본 논문의 목적은, 인공 생명의 원리에 따라 간단한 지역적 규칙으로부터 복잡한 전역적 지능을 형성하는 복수의 자율 이동 로봇의 창발적 행동을 유도하도록 하는 데 있다. 여기서, 강화 신호를 가진 신경 회로망의 학습 구조를 제안하여 이동 로봇이 집단을 이루어 이동할 때 주변의 정보를 센서로 인지하여 움직이는 방향과 속력이 결정되도록 하였다. 시뮬레이션 결과로써, 동적 환경에서 장애물 및 개체간의 충돌을 방지할 뿐 만 아니라 이동 로봇들이 여러 가지 형태를 유지하며 이동하도록 하는 신경 회로망의 최적 하중값을 실시간으로 구하였다. The objective of this paper is, based upon the principles of artificial life, to induce emergent behaviors of multiple autonomous mobile robots which form from simple local rules to complex global intelligence. Here, we propose an architecture of neural network learning with reinforcement signals which perceives the neighborhood information and decides the direction and the velocity of movement as mobile robots navigates in a group. As results of the simulations, the optimum weights are obtained in real time, which not only prevent from the collisions between agents and obstacles in the dynamic environment, but also have the mobile robots move and keep in various patterns.

(+)-Eldanolide의 합성에 관한 연구

강석구,이동하,이정민 성균관대학교 1990 論文集 Vol.41 No.2

출발물질로 D-타타르산 사용하여 (+)-eldanolide의 합성을 연구하였다. 이 합성에서의 중요반응은 온도를 -78℃→0℃로 하여 lithium diisopropylamide 사용하여 (2R, 3R)-1-chloro-2,3-isopropylidenedioxy-6-methy-5-heptene을 탈수소-제거반응시켜 중요한 반응 중간체인 (3R)-6-methyl-heptyn-5-en-3-ol을 합성하는 것이다. Synthetic approach to (+)-eldanolide from D-tartaric acid as starting material is described. They key reaction is the deprotonation-elemination reaction of (2R, 3R)-1-chloro-2, 3-isopropylidenedioxy-6-methyl-5-heptene with lithium diisopropylamide at -78℃→℃ and the key intermediate is (3R)-6-methyl-heptyn-5-en-3-ol.

Tegretol-CR의 抗 躁症 효과에 관한 임상적 연구

강민희,왕성근,신석철 최신의학사 1993 最新醫學 Vol.36 No.7

대두요구르트제조를 위한 두유에서의 젖산균의 산생성과 침전에 관한 연구

강성태,정종민,김제중,정병옥,이흠숙,정석진 서울産業大學校 1999 논문집 Vol.49 No.2

전지두유에 시유를 각각 다른 비율로 혼합하여 제조하여 L. bulgaricus를 접종한 후 산생성에 미치는 효과를 조사하였다. 우유의 첨가량을 늘릴수록 24시간 후의 적정산소가 증가하여 두유에 유유를 혼합시키는 것이 L. bulgaricus에 의한 산생성에 유리함을 알 수 있었다. 전지두유를 100℃에서 30분, 60분, 90분간 가열하고 121℃에서 15분간 열처리하여 L. bulgaricus와 L. casei를 단독으로 접종하거나 1:1(v/v)로 혼합하여 접종하고 두유의 열처리가 산생성과 커드의 침전에 미치는 영향을 평가하였다. 두유의 열처리는 전반적으로 열처리되지 않은 두유보다 산생성을 촉진하였으며 산생성은 가열처리 정도에 비례하였다. 또한 모든 배양에서 121℃ 15분간의 열처리는 100℃ 90분의 열처리보다 낮은 산생성을 보여주었다. 또한 두유의 열처리는 제조된 두유요구르트의 커드의 침전을 지연시키는 효과가 있었다. Soy milk was added with different ratio of market milk. Acid production of L. bulgaricus in mixtures were investigated. Acid production by L. bulgaricus increased in proportion to concentration of milk added to soy milk. And the effects of various heat treatment of soy milk on acid production by L. bulgaricus and L. casei alone or combined were investigated. Sedimentation characteristics of soy yogurt prepared from heat treated soy milk were also evaluated. Heat treatment of soy milk stimulated acid production by all cultures. Acid production was generally proportional to the degree of heat treatment. However, Heat treatment of soy milk at 121℃ for 15min showed rather lower acid production than that at 100℃ for 90 min. Heat treatment of soy milk generally retarded sedimentation of curd in soy yogurt beverage.

방광 크롬친화세포종과 동반된 배뇨후 벼락두통

하윤석,강성진,허소영,이지현,김민정,김종국,김광수 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.1

Thunderclap headache is a hyperacute, severe headache that is so named because the pain strikes suddenly and severely, and is sometimes a sign of a medical emergency. We report a case of pheochromocytoma in the urinary bladder in a 48-year-old woman who presented with recurrent thunderclap headache after voiding and exercise. So we think thunderclap headache during or immediately after micturition may be an important diagnostic clue of bladder pheochromocytoma.