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( Kumar Sanjay ),( Urmil Tuteja ),( Kumari Sarika ),( Dhirendra Kumar Singh ),( Ashok Kumar ),( Om Kumar ) 한국미생물 · 생명공학회 2011 Journal of microbiology and biotechnology Vol.21 No.1
The routine identification and differentiation of Brucella species is a time-consuming and labor-intensive process, which frequently places personnel at risk of laboratory-acquired infection. Here, we describe the development of a rapid multiplex PCR assay for the confirmation of presumptive Brucella isolates. The assay was able to identify and differentiate major human pathogens, namely B. abortus, B. melitensis, and B. suis, in a single test of less than an hour and a half.
Computer-Aided Genetic Algorithm Based Multi-Objective Optimization of Laser Trepan Drilling
Sanjay Kumar,Avanish Kumar Dubey,Arun Kumar Pandey 한국정밀공학회 2013 International Journal of Precision Engineering and Vol. No.
The laser trepan drilling (LTD) has proven to produce better quality holes in advanced materials as compared with laser percussion drilling (LPD). But due to thermal nature of LTD process, it is rarely possible to completely remove the undesirable effects such as recast layer, heat affected zone and micro cracks. In order to improve the hole quality, these effects are required to be minimized. This research paper presents a computer-aided genetic algorithm-based multi-objective optimization (CGAMO) methodology for simultaneous optimization of multiple quality characteristics. The optimization results of the software CGAMO has been tested and validated by the published literature. Further, CGAMO has been used to simultaneously optimize the recast layer thickness (RLT) at entrance and exit in LTD of nickel based superalloy sheet. The predicted results show minimization of 99.82% and 85.06% in RLT at entrance and exit, respectively. The effect of significant process parameters on RLT has also been discussed.
Sanjay Kumar,Sujeet Kumar Singh Gautam,Devendra Gupta,Anil Agarwal,Sanjay Dhirraj,Sandeep Khuba 대한마취통증의학회 2016 Korean Journal of Anesthesiology Vol.69 No.1
Background: Valsalva maneuver reduces pain by activating sinoaortic baroreceptor reflex arc. We planned this study to evaluate the role of valsalva in attenuating spinal needle-puncture pain. Methods: Ninety American Society of Anesthesiologists (ASA) grade I and II enrolled patients undergoing elective surgery were randomized into 3 groups of 30 each. Group I (Control): didn’t blow; group II (Distraction): patients blew into rubber tube; Group III (Valsalva): blew into sphygmomanometer tube and raise mercury column up to 30 mmHg for at least 20 seconds. During above procedures, spinal puncture was performed with 25-gauge spinal needle. Results: Eighty-two patient data were analyzed. Incidence of spinal puncture pain was reduced to 10% (3 of 27) in Valsalva group as compared to 100% (28 of 28 in control group and 27 of 27 in Distraction group) observed in other two groups (P < 0.05). Severity of lumbar puncture pain as assessed by visual analog scale (0−10; where 0 is no pain and 10 is the worst imaginable pain) presented as Median (Interquartile range) were significantly reduced in the Valsalva group (0.0 [0.0] as compared to other 2 groups 2.0 [0.0] in the Distraction group and 3.0 [0.8] in Control group) (P < 0.05). Regarding time taken by CSF to fill spinal needle hub, there was no difference among the three groups (P > 0.05). None patient of all groups had post dural puncture headache (P > 0.05). Conclusions: Valsalva can be performed routinely in ASA I and II patients undergoing spinal anesthesia as it is safe, painless and non-pharmacological method of pain attenuation.
Study of electronic structure and dielectric properties of Gd-doped cobalt nanoferrites
Kumar Arvind,Gora Mahendra Kumar,Kumar Sanjay,Choudhary Banwari Lal,Singhal Rishi Kumar,Dolia Satya Narain 한국물리학회 2022 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.81 No.9
The current article explores the dielectric and electronic properties of cobalt ferrite nanoparticles with Gd substitution in a series CoGdxFe2-xO4 (0≤x≤0.1, in step x=0.02) synthesized by the sol–gel self-combustion way. All the samples were studied with Fourier transform infra-red (FTIR) spectroscopy, Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), and impedance (dielectric) analyzer. One absorption band (υ1) was observed in FTIR measurements, which is the characteristic feature of spinel nanoferrites in fcc type structure. The presence of active Raman modes in Raman spectra at room temperature demonstrated single phase formation of cobalt nanoferrites with metallic–metallic and metallic–oxygen bonding vibrations in the tetrahedral and octahedral sites. XPS data analysis confrmed phase purity and revealed incorporation of Gd ion in the spinel fcc lattice. The valence states of Fe, Co & Gd atoms in all these nanoparticles are found as Fe3+, Co2+, & Gd3+. The dielectric constant and dielectric loss are measured in a broad frequency range of 100 Hz to 120 MHz. The dielectric constant reduces with a rise in Gd concentration and frequency. This study reveals that electronic and dielectric properties could be efectively tuned by varying concentrations of gadolinium in cobalt ferrite nanoparticles.
( Sanjay Kumar ),( Omprakash Sanjeev ),( Anil Agarwal ),( Chetna Shamshery ),( Rakhi Gupta ) 대한통증학회 2018 The Korean Journal of Pain Vol.31 No.1
Background: Venipuncture pain is an uncomfortable suffering to the patient. It creates anxiety, fear and dissatisfaction. The ketoprofen transdermal patch is a proven treatment for musculoskeletal and arthritic pain. We planned this study to evaluate the efficacy of the ketoprofen patch to reduce venipuncture pain. Methods: Two hundred adult patients, aged 18-60 years, of either sex, ASA grade I or II, were enrolled. Presuming that therapy would decrease venipuncture pain by 30%, a power calculation with α = 0.05 and β = 0.80 required enrollment of at least 24 patients into each group. However, 100 patients in each group were recruited. Group I (Control) received a placebo patch; Group II (Ketoprofen) received a 20 mg ketoprofen patch. A selected vein on the dorsum of the patient’s non-dominant hand was cannulated with 18 g intravenous cannula 1 h after the application of the respective patch. Assessment of pain was done by a 10 cm visual analogue scale (VAS) of 0-10, where 0 depicts “no pain” and 10 is “the worst imaginable pain”. The venipuncture site was assessed for the presence of skin erythema, swelling and rashes at 12 h, 24 h and at the time of decannulation. Results: Incidence of pain was 100% (94/94) in the control group as compared to 93% (85/91) in the ketoprofen group. The severity of the venipuncture pain was 6 (2) and 2 (2) for control and ketoprofen groups respectively (P < 0.05). Conclusions: Application of a ketoprofen patch at the proposed site of venipuncture one hour before the attempt is effective and safe for attenuating venipuncture pain. (Korean J Pain 2018; 31: 39-42)
Sanjay Marwah,Shouvik Das,Abhishek Mandal,Ritesh Kumar,Sandeep Chauhan,Krishna Rekha Mantry,Sandeep Kumar Malik 대한외상중환자외과학회 2023 Journal of Acute Care Surgery Vol.13 No.2
Fine needle aspiration (FNA) of the thyroid is a well-tolerated minimally invasive procedure. Thyroid abscess, as a complication of FNA in an immune-competent adult, is extremely rare. Diagnosis requires a high index of suspicion, for which treatment is intravenous antibiotics, drainage, and sometimes surgery. Here we present a case of thyroid abscess in an otherwise healthy man who presented with neck pain, rapidly increasing neck swelling, difficulty in swallowing, and hoarseness of the voice that developed two weeks after diagnostic FNA of a thyroid nodule which had been present for ten months. Despite antibiotic treatment, the abscess ruptured into the trachea, requiring surgical intervention. This highlights the importance of maintaining asepsis during FNA of the thyroid. Timely diagnosis of a thyroid abscess is essential to avoid life-threatening airway complications.
ON ZEROS AND GROWTH OF SOLUTIONS OF SECOND ORDER LINEAR DIFFERENTIAL EQUATIONS
Kumar, Sanjay,Saini, Manisha Korean Mathematical Society 2020 대한수학회논문집 Vol.35 No.1
For a second order linear differential equation f" + A(z)f' + B(z)f = 0, with A(z) and B(z) being transcendental entire functions under some restrictions, we have established that all non-trivial solutions are of infinite order. In addition, we have proved that these solutions, with a condition, have exponent of convergence of zeros equal to infinity. Also, we have extended these results to higher order linear differential equations.
Sanjay Kumar,H. K. Sharma 한국식품과학회 2012 Food Science and Biotechnology Vol.21 No.4
In present study, the effect of crude and commercial enzyme treatment on pineapple (Ananas comosus) juice yield, clarity, and viscosity was studied. A central composite face centered design was used to establish the optimum conditions for enzymatic hydrolysis of pineapple using crude enzyme. The optimized crude enzyme treatment conditions were incubation temperature 47oC, incubation time 446 min, and enzyme concentration 0.14 mL/50 g of pulp. The conditions for the commercial enzyme treatment of the same variety of pineapple to improve the juice recovery and quality were also optimized. The data showed that the crude enzyme was competitive to the commercial enzymes for the improvement of juice recovery and quality from pineapple. The comparison was done under optimized conditions using principal component analysis. As viscosity was the most uncorrelated variable, hence it can be used as a variable to study variance among samples treated by crude and commercial enzymes.