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Poisoning in Korean Children and Adolescents
Woo, Jae Hyug,Ryoo, Eell The Korean Society of Pediatric Gastroenterology 2013 Pediatric gastroenterology, hepatology & nutrition Vol.16 No.4
Drug intoxication in children and adolescents is not uncommon in Korea. But the tendency of intoxication is changing with some factors, such as national surveillance system, Naderism and increasing concern among physicians. But the death rate of intoxication among adolescents is increasing in spite of decreasing total death rate of intoxication among children and adolescents. Therefore the physician must be concerned about the basic management of intoxication and figure out the common toxic substance among children and adolescents.
소아 중증 외상환자의 병원 전 요인에 따른 중증 손상의 예측과 손상의 예방
우재혁 ( Jae Hyug Woo ),양혁준 ( Hyuk Jun Yang ),임용수 ( Yong Su Lim ),조진성 ( Jin Seong Cho ),김진주 ( Jin Joo Kim ),박원빈 ( Won Bin Park ),장재호 ( Jae Ho Jang ),이근 ( Gun Lee ) 대한외상학회 2014 大韓外傷學會誌 Vol.27 No.3
Purpose: Trauma is one of the most common causes of death for children, and identifying severely injured children quickly in an overcrowded emergency room (ER) is difficult. Therefore, severe injury must be prevented, and the severity of injuries in children must be determined easily from their general characteristics and pre-hospital factors. Methods: Injured children younger than 15 years of age who visited the ER from June 2011 to May 2013 were enrolled. According to the revised trauma score (RTS) of the patients, the study population was divided in two groups, a severe group (RTS<7) and a mild group (RTS≥7). The general characteristics and the pre-hospital factors were compared between the two groups. Results: Six hundred seventy-three children were enrolled, their mean age was 8.03 (±4.45) years, and 476 (70.73%) patients were male. Of these patients, 22 patients (3.27%) were in the severe group, and 651 patients (96.73%) were in the mild group. Fewer males were in the severe group than in the mild group (50.00% vs. 71.43%, p=0.030), and children in the severe group were younger than children in the mild group (3.50 vs. 8.00 years, p=0.049). In the severe group, toddlers (54.55%, p=0.036) were the most common age group. Severe injuries occurred more often in spring (32.81%) and summer (54.56%) than in autumn (9.09%) and winter (4.55%) (p=0.026). The most common places of injury in the severe group were roads (50.00%, p=0.009), and the most common mechanisms of injury in the severe group were traffic accidents (50.00%), followed by falls (31.82%) (p=0.011). Most severely injured children were transferred by ambulance (72.73%, p=0.000). Conclusion: The results of this study may be helpful for identifying severely injured children quickly in the field and the ER. To prevent severe pediatric injuries, precautions and policies based on these results should be established. [ J Trauma Inj 2014;27:43-49 ]
Diffractive Optics Fabrication System for Large Aspheric Surface Testing
Hyug-Gyo Rhee,Yun-Woo Lee,Dong-Ik Kim,Jae-Bong Song,Kwan-Soo Ha 한국물리학회 2007 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.50 No.4
A computer-generated hologram (CGH) is widely used for null testing of large aspheric surfaces. The problem is every single aspheric surface requires a different CGH. If various surfaces are to be tested, it is necessary to fabricate various CGHs in the laboratory. To address this, we have developed a cylindrical-type laser writing system, which can fabricate a maximum 300-mm-diameter CGH with about a 0.78-μm spatial resolution in the radial direction. For focusing the writing beam on the material surface, we use the well-known auto-focusing technique with a couple of astigmatic lenses.
문우남(Woo Nam Moon),윤재범(Jae Bum Yoon),양광문(Kwang Moon Yang),양재혁(Jae Hyug Yang) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.2
목적 : 임산부의 증상유발 골반 이완증의 증상 및 유의한 이학적 검사 방법을 알아보고, 증상의 심한 정도, 동통의 정도, 이학적 검사 방법 및 초음파로 측정한 치골관절 간격 사이의 연관성이 있는가를 확인하기 위하여 전향적 연구를 시행하였다. 방법 및 재료 : 골반통 산모 465명을 대상으로 설문지 및 동통 그림표를 이용한 조사를 하여 96명의 골반이완증 환자를 진단하였다. 이들을 대상으로 이학적 검사 및 치골관절의 초음파 검사를 시행하였다. 임상증상, 동통의 정도(Visual analog scale: VAS), 이학적 검사의 양성 유무 및 초음파 검사상의 관절 간격을 비교 분석하여 연관성을 확인하였다. 결과 : 가장 흔한 환자의 불편은 돌아눕기 였다 (100%). 후방 관절통 유발 검사가 가장 유의하였다(85.4%). VAS와 임상증상사이에는 유의한 상관관계가 있었으나 (r=0.340, P=0.001), VAS 혹은 증상과 이학적 검사와의 사이에는 관계가 없었다 (P>0.05). 결론 : 이상의 결과로 임신시의 증상유발 골반이완증을 진단하는데 다른 이학적 검사 방법과 더불어 후방관절 동통 유발 검사를 시행하여 객관적인 진단이 가능 할 것으로 사료 된다. Objective : This prospective study was done to find out common symptoms and beneficial physical examinations, and to evaluate relations among symptom, pain severity, physical examination method and width of symphysis pubis of symptom-giving pelvic girdle relaxation (PGR) in pregnant women. Methods : Four hundreds sixty-five pregnant women who complained pelvic pain were asked to fill out a questionnaire. Ninety-six pregnant women were diagnosed as PGR and were examined physically and took the sonogram. Statistical correlation was evaluated among symptoms, pain severity (visual analog scale: VAS), physical examination method and sonogram. Results : The most common complain was difficulty of rolling in bed (100%). The most frequent positive diagnostic physical method was posterior pelvic pain provocative test (PPPT) (85.4%). There was correlation between VAS and symptoms (r= 0.340, P=0.001) but no correlations between VAS or symptoms and numbers of positive physical examination (P>0.05). Conclusion : It is suggested that PPPT was most beneficial diagnostic methods of PGR in pregnancy.
약제 내성 만성 B형간염 환자에서 테노포비어를 포함한 구원치료의 효과
박재우 ( Park jae woo ),천갑진 ( Gab Jin Cheon ),최강혁 ( Kang Hyug Choi ),이한민 ( Han Min Lee ),전백규 ( Baek Gyu Jun ),김홍수 ( Hong Soo Kim ),김상균 ( Sang Gyune Kim ),김영석 ( Young Seok Kim ),김부성 ( Boo Sung Kim ),정승원 ( 대한소화기학회 2015 대한소화기학회지 Vol.65 No.1
Background/Aims: Tenofovir disoproxil fumarate (TDF) plays a pivotal role in the management of drug-resistant chronic hepatitis B. However, it remains unclear whether TDF-nucleoside analogue combination therapy provides better outcomes than TDF monotherapy. This study aimed to compare the efficacy of TDF monotherapy with that of TDF-nucleoside analogue combination therapy in patients with drug-resistant chronic hepatitis B. Methods: This retrospective cohort study included 76 patients receiving TDF-based rescue therapy for more than 12 months. Suboptimal response was defined as serum HBV-DNA level of >60 IU/mL during prior rescue therapy. Multi-drug resistance was defined as the presence of two or more drug resistance-related mutations confirmed by mutation detection assay. The relationship between baseline characteristics and virologic response (HBV DNA <20 IU/mL) at 12 months were evaluated using logistic regression analysis. Results: Fifty-five patients (72.4%) were suboptimal responders to prior rescue therapy, and 26 (34.2%) had multi-drug resistance. Forty-two patients (55.3%) received combination therapy with nucleoside analogues. Virologic response at 12 months was not significantly different between the TDF monotherapy group and TDF-nucleoside analogue combination therapy group (p=0.098). The serum HBV DNA level was reduced to .4.49±1.67 log10 IU/mL in the TDF monotherapy group and to .3.97±1.69 log10 IU/mL in the TDF-nucleoside analogue combination therapy group at 12 months (p=0.18). In multivariate analysis, female sex (p=0.032), low baseline HBV-DNA level (p=0.013), and TDF monotherapy (p=0.046) were predictive factors for virologic response at 12 months. Conclusions: TDF monotherapy showed similar efficacy to that of TDF-nucleoside analogue combination therapy in patients with drug-resistant chronic hepatitis B.
Jaeik Jang,Jae-Hyug Woo,Mina Lee,Woo Sung Choi,Yong Su Lim,Jin Seong Cho,Jae Ho Jang,Jea Yeon Choi,Sung Youl Hyun The Korean Society of Traumatology 2024 大韓外傷學會誌 Vol.37 No.1
Purpose: This study aimed at developing a novel tube thoracostomy technique using the sternum, a fixed anatomical structure, as an indicator to reduce the possibility of incorrect chest tube positioning and complications in patients with chest trauma. Methods: This retrospective study analyzed the data of 184 patients with chest trauma who were aged ≥18 years, visited a single regional trauma center in Korea between April and June 2022, and underwent chest computed tomography (CT) with their arms down. The conventional gold standard, 5th intercostal space (ICS) method, was compared to the lower 1/2, 1/3, and 1/4 of the sternum method by analyzing CT images. Results: When virtual tube thoracostomy routes were drawn at the mid-axillary line at the 5th ICS level, 150 patients (81.5%) on the right side and 179 patients (97.3%) on the left did not pass the diaphragm. However, at the lower 1/2 of the sternum level, 171 patients (92.9%, P<0.001) on the right and 182 patients (98.9%, P= 0.250) on the left did not pass the diaphragm. At the 5th ICS level, 129 patients (70.1%) on the right and 156 patients (84.8%) on the left were located in the safety zone and did not pass the diaphragm. Alternatively, at the lower 1/2, 1/3, and 1/4 of the sternum level, 139 (75.5%, P=0.185), 49 (26.6%, P<0.001), and 10 (5.4%, P<0.001), respectively, on the right, and 146 (79.3%, P=0.041), 69 (37.5%, P<0.001), and 16 (8.7%, P<0.001) on the left were located in the safety zone and did not pass the diaphragm. Compared to the conventional 5th ICS method, the sternum 1/2 method had a safety zone prediction sensitivity of 90.0% to 90.7%, and 97.3% to 100% sensitivity for not passing the diaphragm. Conclusions: Using the sternum length as a tube thoracostomy indicator might be feasible.