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유아의 또래관계 증진을 위한 학급 단위 프로그램의 개발 및 효과 검증
도현심,김민정,박보경,황영은 이화여자대학교 생활환경대학 인간생활환경연구소 2007 인간생활환경연구소 논집 Vol.- No.5
The purpose of this study was to develop a program for improving peer relations of preschoolers and to investigate its effectiveness, which was held in the natural setting of a classroom. The contents are consisted of understanding emotion, controlling negative emotion, and improving self-esteem, communication skills, and prosocial behaviors. The participants for the study were 105 4-year-o1d preschoolers who were divided into two groups such as experimental and control groups. Among them, 57 children were assigned for the experimental group, and 48 children for the control group. The experimental group participated in the program for 40-50 minutes per day once a week for 12 weeks during both the spring and fall semesters, while the control group received no treatment. As compared to the control group, children in the experimental group showed a significant increase in peer acceptance after they participated in the program, especially for both semesters.
자율 이동 로봇의 행동 학습을 위한 포섭 구조의 공진화
김현영,허광승,심귀보 중앙대학교정보통신연구소 2002 정보통신연구소논문집 Vol.4 No.1
본 논문에서는 자율 이동 로봇의 학습을 위해 신경망과 진화 알고리즘을 이용한 방법을 제안한다. 이것은 자연계의 생물이 진화와 학습을 통해 환경에 적응해 나가는 방식과 유사하다. 또한 본 논문에서는 행동기반 제어 방법인 포섭구조를 이용해 로봇의 행동을 제어하는 방법을 제안한다. 포섭구조는 행동규칙을 병렬적으로 모듈화 하여 낮은 레벨에서는 기본적인 행동을 담당하고, 높은 레벨에서는 좀 더 복잡한 행동을 담당하는 구조로 되어있다. 따라서 각 행동 레벨이 협조를 함으로써 복잡한 임무를 수행할 수 있다. 포섭구조에서 각 레벨의 제어기는 신경망으로 규정하며 각 행동 레벨이 서로 영향을 주고받으며 진화함으로써 주어진 임무를 달성하도록 한다. 제안된 방법은 자율 이동 로봇인 Khepera 로봇을 이용해 실제 환경에서 구현함으로서 그 유효성을 입증한다.
單純回歸模型에서 相關係數에 관한 考察과 假說檢定에 대하여
韓年鍾,沈賢輔 群山大學校 1985 論文集 Vol.11 No.-
In order to estimate and test the population correlation coefficient p, the distribution of the sample correlation coefficient r derived from the sample should be understood. This thesis discusses the p. d. f. f(r) of the sample correlation coefficient r obtained from the bivariate normal distribution under two different cases. One is that the population correlation coefficient p is zero and the other is that nonzero. Finally, the tests of statistical hypothesis have been done saparately.
Hyun-Bo Sim,Eun-Ho Kang,유범희 대한신경정신의학회 2010 PSYCHIATRY INVESTIGATION Vol.7 No.3
ObjectiveaaPanic disorder (PD) is a common and often chronic psychiatric illness, and serotonin-specific reuptake inhibitors (SSRIs) are the drugs of choice for the treatment of PD. Previous studies suggested the cerebral cortex and limbic brain structures played a major role in the development of PD, but the therapeutic effect of SSRIs on specific brain structures remains unclear in PD. We examined the changes in PD patients’ glucose metabolism using the [18F] Fluorodeoxy-glucose-positron emission tomography (FDG-PET) before and after 12 weeks of paroxetine treatment. MethodsaaWe assessed the brain glucose metabolism of 5 PD patients, using the [18F]FDG-PET, and treated them with paroxetine (12.5-37.5 mg/day) for 12 weeks. Then, we compared before and after treatment PET images of the patients, using voxel-based statistical analysis and a post hoc regions of interest analysis. Furthermore, we measured the patients’ clinical variables, including information from the Panic Disorder Severity Scale (PDSS), Clinical Global Impression for Severity (CGI-S), and Hamilton Anxiety Rating Scale (HAMA). ResultsaaAfter 12 weeks of paroxetine treatment, the patients showed significant clinical improvement in terms of PDSS, CGI-S and HAMA scores (12.8±1.8 vs. 3.8±2.3, 4.6±0.5 vs. 2.0±1.4, and 15.2±4.0 vs. 5.0±1.2, respectively; all p values<0.05). After treatment, patients’ glucose metabolism increased significantly in global brain areas: the right precentral gyrus, right middle frontal gyrus, right amygdala, right caudate body, right putamen, left middle frontal gyrus, left precentral gyrus, left insula, left parahippocampal gyrus, and left inferior frontal gyrus (All areas were significant at uncorrected p<0.001 and cluster level corrected p<0.05). ConclusionaaIn these PD patients, cerebral cortex and limbic brain functions changed after short-term treatment with paroxetine. The therapeutic action of paroxetine may be related to altered glucose metabolism at both the cerebral cortex and limbic brain areas.
FCP 6 : Sentinel lymph node biopsy of the 104 malignant melanoma of KNUH over 9 years (2006~2014)
( Hyun Bo Sim ),( Soo Yuhl Chae ),( Yong Hyun Jang ),( Weon Ju Lee ),( Do Won Kim ),( Seok Jong Lee ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2
Background: In these days, Sentinel lymph node biopsy (SLNB) is used as the most sensitive and specific staging tool available for determination of disease status of regional lymph node and it also developed as a technique to surgically assess the regional lymph nodes i.e. sentinel lymph node(SLN) and allowed to spare node-negative patients unnecessary and potentially morbid complete lymphadenectomies. Objectives: To examine the clinical analysis of SLNB cases in Kyungpook national university hospital (KNUH) over 9 years. Methods: In the period from January 2006 to January 2014, a SLNB was performed in 104 patients under cooperation of the department of dermatology, general surgery or orthopedic surgery in KNUH. Data were collected from medical records and the melanoma registry of KNUH. Results: Of the 104 melanoma patients who underwent SLNB, 49 were males (47.1%), 55 were females (52.9%) and their ages ranged from 34~93 years (average: 60.9). Detection rate of SLN was 98.1% (102/104). Twenty nine patients had a tumor-positive SLNB (27.8%) and underwent completion regional lymph node dissection. The mean Breslow thickness of the primary tumors was 3.76 mm, and the proportion of ulcerated melanomas was 51.4%. Two side effects had been observed such as seroma (1case) and lymphocele (1case). Conclusion: Herein, we reviewed the importance of SLNB as prognostic and staging tools with minimal morbidity through our experience of 104 malignant melanoma cases during past 9 years.
Accessary nipple-like ectopic salivary gland in the anterior neck
( Hyun Bo Sim ),( Sun Young Moon ),( Soo Yuhl Chae ),( Yong Hyun Jang ),( Seok Jong Lee ),( Do Won Kim ),( Weon Ju Lee ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1
Ectopic salivary gland is defined as the situation in which the salivary gland tissue develops at a site where it is not normally found. It occurs in various sites within the head and neck region and has even been found in other anatomical sites including anal mucosa. Though the origin of this entity still remains unclear, some reports insist about hypothesis to be a heteroplasia of the epithelium of the precervical sinus of His. A 13-year-old female presented nipple-like erythematous papule with fistula on her right anterior neck since birth. The lesion was mucoid discharge without other symptoms. Under the clinical impression of bronchogenic cyst, the lesion was totally excised. Histopathological examination revealed glandular elements and ducts in deep dermis and fat layer and the gland composed of multiple mucinous acini. Positive staining of mucinous acini with Periodic acid-Schiff(PAS). As accessary nipple-like ectopic salivary gland in the anterior neck is a rare disease with atypical clinical manifestation, it can be easily misdiagnosed as other conditions such as bronchogenic cyst. However ectopic salivary gland shows positive for PAS stain and has characteristic histopathological findings. So diagnosis of ectopic salivary gland can be easily done by histopathological and immunohistochemical examination. We report an informing case of an accessary nipple-like ectopic salivary gland which occurred on the anterior neck.