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Cao Ke-xing,Li Zhao-xing,Li Xin,Lv Zhi-han4 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.3
Aiming at the problem of low accuracy and high computational complexity of the traditional social network community recommendation algorithm, a rapid spanning tree detection algorithm is proposed to independently discriminate social network community with the weak connected edge, in order to improve the accuracy of community recommendation and reduce the complexity of algorithm. Firstly, according to the characteristics of social network community recommendation, the maximum spanning tree algorithm is proposed, which is based on the edge weight distribution node similarity, to realize the effective detection of social network community. Secondly, for the proposed algorithm having the problems of repeated adding and deleting of weakly connected edges and the waste of computing resources, a rapid spanning tree detection algorithm based on the independent discrimination of weakly connected edge is proposed so as to further improve the calculation efficiency of the algorithm. Lastly, the effectiveness of the proposed algorithm is verified by comparing the experimental results in the standard test database.
Cao, Hua-Lian,Kang, Moon-Ho,Lee, Jin-Yong,Park, Won-Jong,Choung, Han-Wool,Choung, Pill-Hoon Korean Association of Maxillofacial Plastic and Re 2020 Maxillofacial Plastic Reconstructive Surgery Vol.42 No.-
Background: To evaluate the facial asymmetry, three-dimensional computed tomography (3D-CT) has been used widely. This study proposed a method to quantify facial asymmetry based on 3D-CT. Methods: The normal standard group consisted of twenty-five male subjects who had a balanced face and normal occlusion. Five anatomical landmarks were selected as reference points and ten anatomical landmarks were selected as measurement points to evaluate facial asymmetry. The formula of facial asymmetry index was designed by using the distances between the landmarks. The index value on a specific landmark indicated zero when the landmarks were located on the three-dimensional symmetric position. As the asymmetry of landmarks increased, the value of facial asymmetry index increased. For ten anatomical landmarks, the mean value of facial asymmetry index on each landmark was obtained in the normal standard group. Facial asymmetry index was applied to the patients who had undergone orthognathic surgery. Preoperative facial asymmetry and postoperative improvement were evaluated. Results: The reference facial asymmetry index on each landmark in the normal standard group was from 1.77 to 3.38. A polygonal chart was drawn to visualize the degree of asymmetry. In three patients who had undergone orthognathic surgery, it was checked that the method of facial asymmetry index showed the preoperative facial asymmetry and the postoperative improvement well. Conclusions: The current new facial asymmetry index could efficiently quantify the degree of facial asymmetry from 3D-CT. This method could be used as an evaluation standard for facial asymmetry analysis.
Han, Bingshe,Wei, Wei,Hua, Fangyuan,Cao, Tingming,Dong, Hua,Yang, Tao,Yang, Yang,Pan, Huazhen,Xu, Caimin Korean Society for Biochemistry and Molecular Biol 2007 Journal of biochemistry and molecular biology Vol.40 No.2
Our previous study has shown that sodium selenite can cause apoptosis in acute promyelocytic leukemia-derived NB4 cells in a caspase-dependent manner, but the detailed mechanism is unknown. Here we demonstrate a requirement for extracellular signal-regulated protein kinase (ERK) in mediating sodium selenite -induced apoptosis in NB4 cell. Though no apparent elevation of ERK activity was observed during the apoptosis in NB4 cells caused by 20 μM sodium selenite treatment, PD98059 and U0126, specific chemical inhibitors of the MEK/ERK signaling pathway, were shown to strongly prevent the apoptosis process, while ERK activator TPA enhanced the process. It is also known that p38 MAPK inhibitor SB203580 and JNK inhibitor SP600125 had slight effects on apoptosis. Further study indicated that ERK exerted its proapoptotic effect only at the early stage of apoptosis and played an antiapoptotic role at the later stages. Taken together, our findings suggest that ERK plays an active role in mediating sodium seleniteinduced apoptosis in NB4 cells .
Damage identification for high-speed railway truss arch bridge using fuzzy clustering analysis
Cao, Bao-Ya,Ding, You-Liang,Zhao, Han-Wei,Song, Yong-Sheng Techno-Press 2016 Structural monitoring and maintenance Vol.3 No.4
This study aims to perform damage identification for Da-Sheng-Guan (DSG) high-speed railway truss arch bridge using fuzzy clustering analysis. Firstly, structural health monitoring (SHM) system is established for the DSG Bridge. Long-term field monitoring strain data in 8 different cases caused by high-speed trains are taken as classification reference for other unknown cases. And finite element model (FEM) of DSG Bridge is established to simulate damage cases of the bridge. Then, effectiveness of one fuzzy clustering analysis method named transitive closure method and FEM results are verified using the monitoring strain data. Three standardization methods at the first step of fuzzy clustering transitive closure method are compared: extreme difference method, maximum method and non-standard method. At last, the fuzzy clustering method is taken to identify damage with different degrees and different locations. The results show that: non-standard method is the best for the data with the same dimension at the first step of fuzzy clustering analysis. Clustering result is the best when 8 carriage and 16 carriage train in the same line are in a category. For DSG Bridge, the damage is identified when the strain mode change caused by damage is more significant than it caused by different carriages. The corresponding critical damage degree called damage threshold varies with damage location and reduces with the increase of damage locations.
Han Zhang,Qi Zhang,Tingting Gao,Yixi Kong,Zeying Qin,Yueyang Hu,Ruilin Cao,Songli Mei 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.5
Objective: This study aims to examine the parallel multiple mediators of depressive symptoms and sleep quality in the relations between stress and physical health-related quality of life (PHQOL)/mental health-related quality of life (MHQOL) among the women in late pregnancy. Methods: Of 1120 pregnant women participated in the cross-sectional study which consisted of Perceived Stress Scale, Edinburgh Postnatal Depression Scale, Pittsburgh Sleep Quality Index and MOS 12-item Short Form Health Survey. Parallel multiple mediator models were used to analyze the relations between stress, depressive symptoms, sleep quality and PHQOL/MHQOL. Results: The effect of perceived stress on PHQOL was partially through the indirect path of sleep quality (β=-0.061). But in the model for MHQOL, depressive symptoms and sleep quality played parallel mediators, and the indirect path effect of depressive symptoms (β=-0.179) was higher than sleep quality (β=-0.029). Conclusion: The findings contributed to the understanding about the influential mechanism of stress on PHQOL/MHQOL. And it reminded the importance of sleep quality and depressive symptoms for improving QOL in late pregnancy.
Han Li,Hua Cao,Rong‑pei Yu,Zhen Miao,Ji‑hua Wang,Su‑Ping Qu,Qiang Yuan,Shenchong Li 한국원예학회 2018 Horticulture, Environment, and Biotechnology Vol.59 No.3
Paphiopedilum pacific shamrock is an orchid with high ornamental value. Understanding the mechanisms responsible for leaf color in albino mutants is important for ornamental development and breeding. In this study, we compared the leaf photosynthetic pigment content and transcriptome of albino mutants ppa01 and wild-type P. pacific shamrock. Photosynthetic pigment in mutants was less than 2% of the wild type and chl a/b was 60% less than the wild type. Transcriptome sequencing yielded 6.27 Gb and 5.67 Gb clean data from the mutant and wild-type leaves, respectively. De novo assembly yielded 104,763 unigenes with 15,400 greater than 1 kb in length. In unigene expression analysis, 3170 differentially expressed genes (DEGs) were identified with 2231 (70.38% of total DEGs) down-regulated. Results from GO and KEGG enrichment analysis, KEGG pathway analysis and qPCR suggest that the reduction of chloroplast biosynthesis and division in the mutant was due to low expression levels of ppGLK1 and ppFtsz. Mutants were associated with fewer chloroplasts in leaf cells, abnormal chloroplast structures, impaired chlorophyll biosynthesis, and thus reduced total chlorophyll and carotenoid contents. Furthermore, down-regulated expression of ppNYC1 reduced transformation of chlorophyll b into chlorophyll a, leading to a chl a/b decline. The research will guide future studies of leaf pigment mutations and the breeding of P. pacific shamrock.
Multi-Residue Analysis of Fipronil and Its Metabolites in Eggs by SinChERS-Based UHPLC-MS/MS
Han, Keguang,Hua, Jin,Zhang, Qi,Gao, Yuanhui,Liu, Xiaolin,Cao, Jing,Huo, Nairui Korean Society for Food Science of Animal Resource 2021 한국축산식품학회지 Vol.41 No.1
A method for simultaneous detection of fipronil (F) and its metabolites fipronil desulfinyl (FD), fipronil sulfide (FS), fipronil sulfone (FSO) in chicken eggs was applied and validated. It includes single-step, cheap, effective, rugged, safe-based method (SinChERS) for sample preparation and ultra high performance liquid chromatography coupled with mass spectrometry (UHPLC-MS/MS) for chemical analysis. Results suggested that formic acid enhanced the recovery of 4 target residues and 1% supplementation to acetonitrile gained higher recoveries than that of 5%. SinChERS integrated extraction and clean-up steps into one, with shorter time (1.5 h) to operate and higher recoveries (97%-100%) than HLB, Envi-Carb-NH2 and quik-easy-cheap-effective-rugged-safe method (QuEChERS), and it consumed the smallest volume of extracting solvent (10 mL) as QuEChERS. Quantitative analyses using external standard method suggested the linear ranges of 4 target compounds were 1-20 ㎍/L with R2 >0.9947. The limit of detection (S/N>3) and quantification (S/N>10) were 0.3 ㎍/kg and 1 ㎍/kg. Recoveries ranged from 89.0% to 104.4%, and the relative standard deviations (n=6) at 1, 10, and 20 ㎍/kg were lower than 6.03%. Thirty batches of domestic eggs (500 g each) were detected by the established SinChERS-based UHPLC-MS/MS and no target residues were detected in all samples. The method developed in this study is a rapid, sensitive, accurate and economic way for multi-residue analysis of fipronil and its metabolites in eggs.
Online monitoring of IGBT junction temperature based on V<sub>ce</sub> measurement
Cao, Han,Ning, Puqi,Chai, Xiaoguang,Zheng, Dan,Kang, Yuhui,Wen, Xuhui The Korean Institute of Power Electronics 2021 JOURNAL OF POWER ELECTRONICS Vol.21 No.2
In this paper, an online junction temperature monitoring method based on the on-state voltage under high collector current density measurements for IGBT power modules is proposed. Unlike the conventional junction temperature monitoring method, the presented method can extract the junction temperature during operation without altering the modulation strategy or topology of the converter. The proposed method is verified by simulations and the JEDEC-51 standard recommended approach. To accurately extract the on-state voltage during operation, a measurement circuit that combines the advantages of both the active MOSFET clamp and the diode clamp is designed and tested. It has been shown to have good accuracy and a rapid response time. After the calibration results are obtained, the presented method is applied to a three-phase voltage source converter controlled by a closed-loop SVPWM modulation strategy.