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정웅교(Woong-Kyo Chung),김진호(Jin-Ho Kim),이우기(Woo-Key Lee) 한국정보과학회 2001 한국정보과학회 학술발표논문집 Vol.28 No.2Ⅰ
데이터웨어하우스내에서 실체뷰는 소스 데이터에서 갱신이 발생하였을 경우 질의에 정확한 결과를 제공하기 위하여 릴레이션의 변경사항과 동일하게 갱신되어야 한다. 이 뷰를 갱신할 때 전체 릴레이션이 아닌 갱신된 부분만 이용하여 점진적으로 뷰를 관리하는 것이 효과적이다. 뷰의 점진적인 갱신 방법중에서 부가화일을 이용한 방법은 부가적으로 유지하는 정보의 양이 적고 뷰 관리 비용이 적게 든다는 장점이 있다. 이 논문에서는 이 방법에 의해 뷰를 관리할 때의 성능을 평가하기 위하여 이 방법의 비용 모델을 분석적으로 제시하였으며, 이 모델을 기반으로 성능을 비교, 분석하여 부가 파일을 이용한 방법이 다른 기존의 방법보다 성능이 우수함을 보였다.
실험적 뇌허혈증 모델에서 허혈 조직의 99mTc - glucarate 섭취
고창순(Chang Soon Koh),이명철(Myung Chul Lee),정준기(June Key Chung),이동수(Dong Soo Lee),김영주(Young Ju Kim),정재민(Jae Min Jeong),김채균(Chae Kyun Kim),최석례(Seok Rye Choi),마응천(Woong Chun Mar) 대한핵의학회 1996 핵의학 분자영상 Vol.30 No.4
N/A To detect ischemic tissue in experimental model of cerebral ischemia made by middle cerebral artery(MCA)-occlusion, we acquired triple image of Tc-99m-glucarate, [18F]fluoro-deoxyglucose (FDG), and 2,3,5-triphenyltetrazolium (TTC) staining. We made cerebral infarction either with reperfusion (after occlusion of 2 hours) or without reperfusion in 10 Sprague-Dawley rats by inserting thread to MCA through internal carotid artery. After 22 hours, we injected 740 MBq of Tc-99m-glucarate and 55.5 MBq of [18F]FDG through tail vein. Each 1 mm slice of rat brains was frozen and exposed to imaging plate for 20 minutes in freezer to get an [18F]FDG image. After 20 hours enough to fade radioactivity of [18F]FDG, the slices were again imaged by BAS1500 for Tc-99m-glucarate uptake·Finally, these braim tissues were stained with TTC. semi-quantitative visual analysis was done by grading 0 to 3 points according to the degree of uptakes(Tc-99m-glucarate) and decreased uptakes([18F]FDG and TTC). Ten rats survived with neurologic symptoms. TTC staining confirmed the development of infarction. The size of the infarction was relatively larger in the group without reperfusion. [18F]FDG images were similar to TTC-stained images. However, we found regions with intermediate uptake which were not stained with TTC. We found regions with intermediate [18F]FDG uptake where TTC staining was normal. Tc-99m-glucarate uptake was found only in TTC non-stained region. In the TTC stained regions, there were no uptake of Tc-99m-glucarate. We could not find clear relation between Tc-99m- glucarate uptake with [18F]FDG uptake. This was partly because percent uptake of Tc-99m- glucarate was so small (less than 1 percent of injected dose) and because there were quite heterogeneity of patterns of [18F]FDG uptake and TTC. With these findings, we could conclude that Tc-99m-glucarate were taken up only in part of ischemic tissues which were proven to be nonviable. The establishment of MCA-occluded rat model with or without reperfusion and triple imaging for Tc-99m, 18F and TTC helped the characterzation of Tc-99m-glucarate uptakes. Further work is needed to clarify the meaning of diversities of [18F]FDG and TTC and their relation with Tc-99m-glucarate.
Metastatic follicular struma ovarii complicating pregnancy
Woohyung Lee,Nam-Joon Yi,Hyeyoung Kim,Youngrok Choi,Minsu Park,Geun Hong,June Young Choi,Hyun Hoon Chung,Kwang-Woong Lee,Do-Joon Park,Hye Sook Min,June-key Chung,Kyung-Suk Suh 한국간담췌외과학회 2012 한국간담췌외과학회지 Vol.16 No.3
A 35-year-old woman was determined to have an ovarian cyst and underwent a right ovarian cystectomy at 10 weeks of gestation. A histopathological examination revealed follicular carcinoma arising in a teratoma. No evidence of metastasis was found after delivery. She underwent a total thyroidectomy, followed by radioactive iodine (RAI) therapy. However, her serum thyroglobulin level increased to 1,437 ng/ml (normal range: 0-52 ng/ml) after 10 months. Radioiodine scintigraphy and abdominal computed tomography revealed liver metastasis and peritoneal seeding. She underwent debulking surgery of the liver, right salpinx, and peritoneal seeding nodules. A pathological examination showed metastatic follicular carcinoma with focal poorly differentiated features. Adjuvant RAI therapy was restarted, and her serum thyroglobulin levels returned to normal. In conclusion, metastatic lesions were successfully treated with a combination of debulking surgery and RAI therapy. Close medical follow-up monitoring serum thyroglobulin levels is mandatory in such patients.