성견 하악골에서 다양한 드릴링 속도에 따른 임플란트 초기 골유착에 관한 비교 연구 = Comparative study on early osseointegration of implants according to various drilling speeds in the mandible of dogs

다국어 초록 (Multilingual Abstract)

I. Purpose
Successful osseointegration of implants can be influenced by the drilling speeds of implant installation. This study evaluated the effect of drilling speed on early bone healing in mandible of dogs.

II. Material and methods
Six young adult dogs were selected and two mandibular premolars and two molars were extracted from both sides. After two months of healing, 3 hydroxyapatite surfaced Ф3.7*10mm fixtures (OneQ, Dentis, Daegu, Korea) were implanted with drilling speeds of 50, 800, and 1200 rpm on the right side first and then the left side after 2 weeks. Implant stability quotient (ISQ) was measured upon insertion, and after 4 weeks for the right side, and after 2 weeks for the left side using Osstell Mentor®. The animals were euthanized after allowing 4 weeks and 2 weeks of healing for the right and left side of the mandible, respectively. The implant and surrounding tissue were histologically analyzed.
III. Results
The implants were stable upon insertion for both groups and although implant stability steadily increased for 4 weeks, no statistically significant differences were observved between the surgical protocols.
From histomorphological evaluation, a significant increase from 2 to 4 weeks was observed for all groups for bone-implant contact(BIC), whereas no significant differences were detected between 2 and 4 weeks for the 50 and 800 rpm groups.
Based on the ISQ measurement, all implants were measured higher than 60 for each drilling speed from both 2 and 4 weeks group. The 1200 rpm group showed a higher value than the 50 rpm group at 2 weeks and 4 weeks. (p<0.05)
From the results of a histomorphometric analysis, new bone formation around the implant was highest for the 800 rpm group at 2 weeks and the 1200 rpm group at 4 weeks. The BIC of the superior half of the alveolar bone was highest for the 800 rpm group at 2 weeks and the 1200 rpm group at 4 weeks. There was no statistically significant differences.

IV. Conclusion
This study suggests that 50, 800, and 1200 rpm are drilling speeds which can expect favorable outcome, yet, higher drilling speed presented overall the best biological responses. However, further studies are needed for statistical significance.

목차 (Table of Contents)

• ABSTRACT ⅳ
• Ⅰ. 서 론 1
• Ⅱ. 실험재료 및 방법 3
• Ⅲ. 결과 7
• Ⅳ. 고찰 9
• Ⅴ. 결론 11
• VI. 참고문헌 12