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Eo, Jae Seon,Kim, Hyun Koo,Kim, Sungeun,Lee, Yun-Sang,Jeong, Jae Min,Choi, Young Ho Raven Press 2015 Annals of Surgical Oncology Vol.22 No.2
<P>To develop imaging of lymphatics with resolution greater than that of lymphoscintigraphy using technetium-99??m neomannosyl human serum albumin ((99m)Tc-MSA), we developed a Gallium-68 ((68)Ga) MSA for positron emission tomography (PET). This study is the first clinical trial to evaluate the feasibility of sentinel node detection using this novel (68)Ga tracer for the management of non-small cell lung cancer.</P>
Shin, Dong Wook,Cho, Juhee,Kim, So Young,Guallar, Eliseo,Hwang, Seung Sik,Cho, Belong,Oh, Jae Hwan,Jung, Ki Wook,Seo, Hong Gwan,Park, Jong Hyock Raven Press 2013 Annals of surgical oncology Vol.20 No.8
<P>Surgery for cancer is often delayed due to variety of patient-, provider-, and health system-related factors. However, impact of delayed surgery is not clear, and may vary among cancer types. We aimed to determine the impact of the delay from cancer diagnosis to potentially curative surgery on survival.</P>
Choi, Chel Hun,Lee, Jeong-Won,Lee, Yoo-Young,Kim, Ha-Jeong,Song, Taejong,Kim, Min-Kyu,Kim, Tae-Joong,Kim, Byoung-Gie,Bae, Duk-Soo Raven Press 2012 Annals of surgical oncology Vol.19 No.12
<P>The aim of this study was to compare the surgical and oncologic outcomes of laparoscopic-assisted radical vaginal hysterectomy (LARVH) with that of laparoscopic radical hysterectomy (LRH) for early-stage cervical cancer.</P>
Clinicopathologic risk factors for the local recurrence of phyllodes tumors of the breast.
Jang, Jae Hyuck,Choi, Min-Young,Lee, Se Kyung,Kim, Sangmin,Kim, Jiyoung,Lee, Jeonghui,Jung, Seung Pil,Choe, Jun-Ho,Kim, Jung-Han,Kim, Jee Soo,Cho, Eun Yoon,Lee, Jeong Eon,Nam, Seok Jin,Yang, Jung-Hyun Raven Press 2012 Annals of surgical oncology Vol.19 No.8
<P>Phyllodes tumors (PTs) are rare breast tumors that usually occur in middle-aged women. Here we discuss our recent experiences in the diagnosis, surgical management, and clinical follow-up of this disease.</P>
Diagnostic accuracy of fine needle aspiration cytology for high-grade salivary gland tumors.
Kim, Bo Young,Hyeon, Jiyeon,Ryu, Gwanghui,Choi, Nayeon,Baek, Chung-Hwan,Ko, Young-Hyeh,Jeong, Han-Sin Raven Press 2013 Annals of surgical oncology Vol.20 No.7
<P>Preoperative differentiation between high-grade malignancy and others (benign or low-grade tumors) is more important than differentiation between malignant and benign tumors for surgical planning, treatment outcome, and prognosis in salivary gland tumors. Fine needle aspiration cytology (FNAC) has a relatively low sensitivity for differentiating malignant from benign salivary tumors. However, the diagnostic performance of FNAC has not been studied in predicting high-grade salivary malignancy, which can significantly affect patient care.</P>
Park, Young Min,Lee, Won Jai,Yun, In Sik,Lee, Dong Won,Lew, Dae Hyun,Lee, Jeon Mi,Ha, Jong-Gyun,Kim, Won Shik,Koh, Yoon Woo,Choi, Eun Chang Raven Press 2013 Annals of surgical oncology Vol.20 No.3
<P>We performed robot-assisted neck dissection (RAND) via a modified face-lift (MFLA) or retroauricular approach for neck management and carried out free flap reconstruction via these approaches in patients with head and neck cancer. We assessed the feasibility of free flap reconstruction in patients who had undergone transoral resection of a primary lesion and RAND via these approaches.</P>
Min, Kyueng-Whan,Park, Moon Hyang,Hong, Sung Ran,Lee, Heejung,Kwon, Sun Young,Hong, Sook Hee,Joo, Hee Jae,Park, In Ae,An, Hee Jung,Suh, Kwang Sun,Oh, Hoon Kyu,Yoo, Chong Woo,Kim, Mi Jin,Chang, Hee Kyu Raven Press 2013 International journal of gynecological pathology Vol.32 No.1
<P>Accurate diagnosis of ovarian clear cell carcinoma (CCC) is important because of its poor prognosis with chemoresistance and a high recurrent rate. The clinicopathologic characteristics and prognostic significance of the cell cycle regulator [early mitotic inhibitor-1 (Emi1)] and galactoside-binding protein (Galectin-3) were evaluated. Among 155 CCCs from 18 hospitals in Korea between 1995 and 2006, 129 pure CCCs were selected with consensus using immunohistochemical stains for hepatocyte nuclear factor-1β, Wilms' tumor protein, and estrogen receptor. The expressions of Emi1, Galectin-3, p53, and Ki-67 labeling index were analyzed with clinicopathologic parameters and the patient's survival. The mean age of the patients was 49.6 yr; the tumors were bilateral in 10.9%, and the average size was 12 cm. Adenofibromatous component was found in 7%, and endometriosis in 48.1% of the cases. Psammoma body was seen in 16.3%. Disease-free survival and overall survival rates were 78.3% and 79.1%, respectively. The International Federation of Obstetrics and Gynecology (FIGO) stage was the most important prognostic indicator. Emi1 expression (>5%) was seen in 23.3% of CCCs, and associated with high FIGO grades and poor overall survival (P<0.05). High Galectin-3 (80%) expression was seen in 59.7% of CCCs, and associated with FIGO stages III and IV, and high Ki-67 labeling index. High Ki-67 labeling index (50%) and p53 expression (50%) were seen in 27.1% and 18.6% of CCCs, respectively, but there was no clinicopathologic and prognostic significance. On the basis of the fact that the expression of Emi1 in CCC was correlated with a high histologic grade and worse overall survival, target therapy using inhibitors of Emi1 may be tried in the management of CCC patients with Emi1 expression.</P>
Lee, Hee Jin,Seol, Hyang Sook,Kim, Joo Young,Chun, Sung-Min,Suh, Young-Ah,Park, Young-Soo,Kim, Sang-we,Choi, Chang-Min,Park, Seung-Il,Kim, Dong Kwan,Kim, Yong-Hee,Jang, Se Jin Raven Press 2013 Annals of surgical oncology Vol.20 No.1
<P>Microarray analyses have revealed significantly elevated expression of the proto-oncogene ROS1 receptor tyrosine kinase in 20-30% of non-small cell lung carcinomas (NSCLC). Selective and potent ROS1 kinase inhibitors have recently been developed and oncogenic rearrangement of ROS1 in NSCLC identified.</P>
Shin, Hee-Chul,Han, Wonshik,Moon, Hyeong-Gon,Im, Seock-Ah,Moon, Woo Kyung,Park, In-Ae,Park, Sung Jun,Noh, Dong-Young Raven Press 2013 Annals of surgical oncology Vol.20 No.8
<P>We conducted a retrospective study to evaluate the local recurrence (LR) rate depending on the use of neoadjuvant chemotherapy (NCT) and to determine the oncologic safety of breast-conserving surgery (BCS) after NCT by comparing LR between patients treated with BCS and mastectomy in clinical stage III breast cancer patients.</P>
Lee, Jae Seok,Kim, Hye Ryun,Lee, Chang Young,Shin, Mihwa,Shim, Hyo Sup Raven Press 2013 Annals of surgical oncology Vol.20 No.9
<P>Gene amplifications are implicated in cancer development and progression. In this study we investigated the clinicopathologic characteristics associated with EGFR or TTF-1 amplification in lung adenocarcinomas and its prognostic significance.</P>