RISS 검색 - 국내학술지논문

무료
기관 내 무료
유료

내보내기
내책장담기
한글로보기

정확도순

내림차순

내림차순

10개씩 출력

1
Phylogenetic and expression analysis of the angiopoietin-like gene family and their role in lipid metabolism in pigs

Zibin Zheng,Wentao Lyu,Qihua Hong,Hua Yang,Ying Li,Shengjun Zhao,Ying Ren,Yingping Xiao Asian Australasian Association of Animal Productio 2023 Animal Bioscience Vol.36 No.10
- 원문보기 2
  ScienceON
  
  KCI
Objective: The objective of this study was to investigate the phylogenetic and expression analysis of the angiopoietin-like (ANGPTL) gene family and their role in lipid metabolism in pigs. Methods: In this study, the amino acid sequence analysis, phylogenetic analysis, and chromosome adjacent gene analysis were performed to identify the ANGPTL gene family in pigs. According to the body weight data from 60 Jinhua pigs, different tissues of 6 pigs with average body weight were used to determine the expression profile of ANGPTL1-8. The ileum, subcutaneous fat, and liver of 8 pigs with distinct fatness were selected to analyze the gene expression of ANGPTL3, ANGPTL4, and ANGPTL8. Results: The sequence length of ANGPTLs in pigs was between 1,186 and 1,991 bp, and the pig ANGPTL family members shared common features with human homologous genes, including the high similarity of the amino acid sequence and chromosome flanking genes. Amino acid sequence analysis showed that ANGPTL1-7 had a highly conserved domain except for ANGPTL8. Phylogenetic analysis showed that each ANGPTL homologous gene shared a common origin. Quantitative reverse-transcription polymerase chain reaction analysis showed that ANGPTL family members had different expression patterns in different tissues. ANGPTL3 and ANGPTL8 were mainly expressed in the liver, while ANGPTL4 was expressed in many other tissues, such as the intestine and subcutaneous fat. The expression levels of ANGPTL3 in the liver and ANGPTL4 in the liver, intestine and subcutaneous fat of Jinhua pigs with low propensity for adipogenesis were significantly higher than those of high propensity for adipogenesis. Conclusion: These results increase our knowledge about the biological role of the ANGPTL family in this important economic species, it will also help to better understand the role of ANGPTL3, ANGPTL4, and ANGPTL8 in lipid metabolism of pigs, and provide innovative ideas for developing strategies to improve meat quality of pigs.
2
A Global Graph-based Approach for Transaction and QoS-aware Service Composition

( Hai Liu ),( Zibin Zheng ),( Weimin Zhang ),( Kaijun Ren ) 한국인터넷정보학회 2011 KSII Transactions on Internet and Information Syst Vol.5 No.7
- 원문보기 2
  ScienceON
  
  KISS
In Web Service Composition (WSC) area, services selection aims at selecting an appropriate candidate from a set of functionally-equivalent services to execute the function of each task in an abstract WSC according to their different QoS values. In despite of many related works, few of previous studies consider transactional constraints in QoS-aware WSC, which guarantee reliable execution of Composite Web Service (CWS) that is composed by a number of unpredictable web services. In this paper, we propose a novel global selection-optimal approach in WSC by considering both transactional constraints and end-to-end QoS constraints. With this approach, we firstly identify building rules and the reduction method to build layer-based Directed Acyclic Graph (DAG) model which can model transactional relationships among candidate services. As such, the problem of solving global optimal QoS utility with transactional constraints in WSC can be regarded as a problem of solving single-source shortest path in DAG. After that, we present Graph-building algorithms and an optimal selection algorithm to explain the specific execution procedures. Finally, comprehensive experiments are conducted based on a real-world web service QoS dataset. The experimental results show that our approach has better performance over other competing selection approaches on success ratio and efficiency.