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Xu, Zhuang,Rahman, M.F.,Wang, G.,Xu, Dianguo The Korean Institute of Power Electronics 2012 JOURNAL OF POWER ELECTRONICS Vol.12 No.1
This paper presents performance evaluation of an Integrated Starter-Alternator (ISA) prototype with an Interior Permanent Magnet (IPM) synchronous machine under sensor-less operation. To attain a high starting torque at zero speed and in subsequent extremely low speed range, a hybrid signal injection method is proposed. At higher speed, an improved stator flux observer is used for the stator flux estimation. This observer is able to produce accurately-estimated stator flux linkage for high performance Direct Torque and Flux Control (DTFC) implementation. The sensor-less DTFC IPM synchronous machine drive takes full advantage of the capacity of the power converter and fulfills the control specifications for the ISA. The trajectory control algorithm responds rapidly and in a well behaved manner over a wide range of operating conditions. The experimental results verify the feasibility and advantages of the system.
Zhuang Xu,M. F. Rahman,G. Wang,Dianguo Xu 전력전자학회 2012 JOURNAL OF POWER ELECTRONICS Vol.12 No.1
This paper presents performance evaluation of an Integrated Starter-Alternator (ISA) prototype with an Interior Permanent Magnet (IPM) synchronous machine under sensor-less operation. To attain a high starting torque at zero speed and in subsequent extremely low speed range, a hybrid signal injection method is proposed. At higher speed, an improved stator flux observer is used for the stator flux estimation. This observer is able to produce accurately-estimated stator flux linkage for high performance Direct Torque and Flux Control (DTFC) implementation. The sensor-less DTFC IPM synchronous machine drive takes full advantage of the capacity of the power converter and fulfills the control specifications for the ISA. The trajectory control algorithm responds rapidly and in a well behaved manner over a wide range of operating conditions. The experimental results verify the feasibility and advantages of the system.
Zhuang Bao-Jun,Xu Su-Yun,Dong Liang,Zhang Pei-Hai,Zhuang Bao-Lin,Huang Xiao-Peng,Li Guang-Sen,You Yao-Dong,Chen Di'Ang,Yu Xu-Jun,Chang De-Gui 대한남성과학회 2022 The World Journal of Men's Health Vol.40 No.4
The protein encoded by dynein axonemal heavy chain 1 (DNAH1) is a part of dynein, which regulates the function of cilia and sperm flagella. The mutant of DNAH1 causes the deletion of inner dynein arm 3 in the flagellum, leading to multiple morphological abnormalities of the sperm flagella (MMAF) and severe asthenozoospermia. However, instead of asthenozoospermia and MMAF, the result caused by the mutation of DNAH1 remains unknown. Here we report a male infertility patient with severe asthenozoospermia and teratozoospermia. We found two heterozygous mutations in DNAH1 (c.6912C>A and c.7076G>T) and which were reported to be associated with MMAF for the first time. We next collected and analyzed 65 cases of DNAH1 mutation and found that the proportion of short flagella is the largest, while the bent flagella account for the smallest, and the incidence of head deformity is not high in the sperm of these patients. Finally, we also analyzed 31 DNAH1 mutation patients who were treated with intracytoplasmic sperm injection (ICSI) and achieved beneficial outcomes. We hope our research will be helpful in the diagnosis and treatment of male infertility caused by DNAH1 mutation.
An Optimized Nonlinear Extended State Observer for Sensorless IPM Synchronous Motor Drives
Zhuang Xu,Tianru Zhang,Chris. Gerada 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5
a nonlinear Third-Order Extended State Observer (TESO) is proposed for the estimation of the rotor position and speed for sensorless Interior Permanent Magnet (IPM) synchronous motor drives. An optimized parameter tuning method is deployed to reconcile the needs of expanding the disturbance observation bandwidth and suppressing the measurement noise effectively. Both the steady state and transient performance of the TESO are verified through the experimental tests. In comparison with the performance of a conventional Linear Extended State Observer (LESO), the proposed observer is proved to have better noise suppression ability and disturbance observation performance in wide operating range.
The role and mechanism of lncRNA NEAT1 in the fibrosis of pulmonary epithelial cell
Hui Xu,YanBo Chen,Jinqiang Zhuang,Shun Zhu,Bing Xu,Jiang Hong 대한독성 유전단백체 학회 2020 Molecular & cellular toxicology Vol.16 No.2
Background Pulmonary fibrosis is a serious clinical fatal disease. Epithelial–mesenchymal transition (EMT) and lncRNA NEAT1 have been implied in its development and progression. Objective To study the role of lncRNA NEAT1 in the progression of fibrosis in human pulmonary epithelial cells (BEAS- 2B). Specifically, BEAS-2B was transfected with NEAT1 and miR-29c, EMT and cell proliferation were measured and the expression level of relevant genes was determined by Western blot. Result Results showed that NEAT1 promotes fibrosis and proliferation of BEAS-2B cells via the up-regulation of α-SMA, Vimentin, Snail and proliferation-related genes including Cyclin D1 and Cyclin E; miR-29c is a target gene of NEAT1 and through which NEAT1 regulates EMT and expression of proliferation-related genes. Conclusion This study investigated the mechanism of pulmonary fibrosis progression by elucidating the role of NEAT1/ miR-29c in the fibrosis and proliferation of BEAS-2B cells, thus providing a basis for the new therapeutic targets of pulmonary fibrosis.
Cavitation in a Shaft-less Double Suction Centrifugal Miniature Pump
Zhuang, Baotang,Luo, Xianwu,Zhu, Lei,Wang, Xin,Xu, Hongyuan Korean Society for Fluid machinery 2011 International journal of fluid machinery and syste Vol.4 No.1
Based on the consideration that the cavitation would affect the operation stability of miniature pumps, the 3-D turbulent cavitating flow in a test pump was simulated by using a mixed cavitation model and k-${\omega}$ SST turbulence model. In order to investigate the influence of inlet geometry parameters on the cavitation performance of the miniature pump, two more impellers are designed for comparison. Based on the results, the following conclusions are drawn: 1) Cavitation performance of the double suction shaft-less miniature pump having different impeller is equivalent to the centrifugal pump having ordinary size, though the flow passage at impeller inlet is small; 2) The miniature pump having radial impeller can produce much higher pump head, but lower cavitation performance than that having the impeller based on the conventional design method; 3) It is believed that by applying the double suction design, the miniature pump achieved relatively uniform flow pattern upstream the impeller inlet, which is favorable for improving cavitation performance.
Zhuang Wang,Se Wang,MINDONG CHEN,Defu Xu,Lili Tang,Degao Wang 대한화학회 2015 Bulletin of the Korean Chemical Society Vol.36 No.6
Simulations at multiple levels were performed to investigate the aqueous adsorption of phthalate esters (PAEs) on carbon nanoparticles and to find the competitive effect of a low molecular weight natural organic acid (benzoic acid) on the adsorption process. Six PAEs of varying alkyl side chain lengths and three carbon-based nanomaterials including a single-walled carbon nanotube (SWNT), double-walled carbon nanotube (DWNT), and graphene (G) were studied. Results showed that the adsorption energies calculated using density functional theory increase with increasing length of the PAE alkyl chain. G exhibits higher adsorption capacity for the PAEs than SWNT and DWNT. The absolute adsorption energies of these systems also display a positive linear correlation with the hydrophobicity of the PAE molecules. Molecular dynamics simulations indicate that the presence of neutral/anionic benzoic acid in water alleviates the PAE adsorption. Furthermore, anionic benzoic acid exerts more impact on the PAE adsorption than the neutral form.