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Establishing a Nomogram for Stage IA-IIB Cervical Cancer Patients after Complete Resection
Zhou, Hang,Li, Xiong,Zhang, Yuan,Jia, Yao,Hu, Ting,Yang, Ru,Huang, Ke-Cheng,Chen, Zhi-Lan,Wang, Shao-Shuai,Tang, Fang-Xu,Zhou, Jin,Chen, Yi-Le,Wu, Li,Han, Xiao-Bing,Lin, Zhong-Qiu,Lu, Xiao-Mei,Xing, H Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9
Background: This study aimed to establish a nomogram by combining clinicopathologic factors with overall survival of stage IA-IIB cervical cancer patients after complete resection with pelvic lymphadenectomy. Materials and Methods: This nomogram was based on a retrospective study on 1,563 stage IA-IIB cervical cancer patients who underwent complete resection and lymphadenectomy from 2002 to 2008. The nomogram was constructed based on multivariate analysis using Cox proportional hazard regression. The accuracy and discriminative ability of the nomogram were measured by concordance index (C-index) and calibration curve. Results: Multivariate analysis identified lymph node metastasis (LNM), lymph-vascular space invasion (LVSI), stromal invasion, parametrial invasion, tumor diameter and histology as independent prognostic factors associated with cervical cancer survival. These factors were selected for construction of the nomogram. The C-index of the nomogram was 0.71 (95% CI, 0.65 to 0.77), and calibration of the nomogram showed good agreement between the 5-year predicted survival and the actual observation. Conclusions: We developed a nomogram predicting 5-year overall survival of surgically treated stage IA-IIB cervical cancer patients. More comprehensive information that is provided by this nomogram could provide further insight into personalized therapy selection.
Two-Step Reset in the Resistance Switching of the Al/TiO<sub><i>x</i></sub>/Cu Structure
Shao, Xing L.,Zhao, Jin S.,Zhang, Kai L.,Chen, Ran,Sun, Kuo,Chen, Chang J.,Liu, Kai,Zhou, Li W.,Wang, Jian Y.,Ma, Chen M.,Yoon, Kyung J.,Hwang, Cheol S. American Chemical Society 2013 ACS APPLIED MATERIALS & INTERFACES Vol.5 No.21
<P>Two-step reset behaviors in the resistance switching properties of the top Al/TiO<SUB><I>x</I></SUB>/bottom Cu structure were studied. During the electroforming and set steps, two types of conducting filaments composed of Cu and oxygen vacancies (Cu-CF and V<SUB>O</SUB>-CF) were simultaneously (or sequentially) formed when Al was negatively biased. In the subsequent reset step with the opposite bias polarity, the Cu-CFs ruptured first at ∼0.5 V, and formed an intermediate state. The trap-filled V<SUB>O</SUB>-CFs were transformed into a trap-empty state, resulting in a high-resistance state at ∼1 V. Matrix phase in the electrochemical metallization cell can play an active role in resistance switching.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2013/aamick.2013.5.issue-21/am403498q/production/images/medium/am-2013-03498q_0007.gif'></P>
FATE AND METABOLISM OF NITROGEN IN GOATS FED <sup>15</sup>N-LABELLED RICE STRAW
Xing, T.X.,He, D.Y.,He, L.H.,Zhou, W.J.,Liao, X.L.,Chen, H.P. Asian Australasian Association of Animal Productio 1992 Animal Bioscience Vol.5 No.4
Three goats were fed with $^{15}N$-labelled rice straw to study the characteristics of digestion, assimilation, metabolism and excretion of C and N compounds from rice straw. It was shown that the amount of $^{15}N$ assimilated into the bodies of the two slaughtered goats accounted for 38.5 and 23.6% of the total amount of $^{15}N$ ingestion in the experimental diet by each goat. The $^{15}N$ excreted via the feces and urine for the three goats accounted for 34.8, 33.2 and 33.9% of the total amount of $^{15}N$ ingested in the feed of the 3 goats. The recoveries of $^{15}N$ from the two slaughtered goats were 73.3 and 57.5%, with the corresponding rates of $^{15}N$ loss 26.7 and 42.5% respectively. The amino acids digestibilities were 68.7 and 54.0%, while the digestibilities of carbohydrates were 74.8 and 67.7% respectively for goats 1 and 3.
Xing Jie,Zhao Qinqin,Chen Huiling,Zhang Yili,Zhou Feng,Zhao Hanli 한국CDE학회 2023 Journal of computational design and engineering Vol.10 No.6
We present a bee foraging behavior-driven mutational salp swarm algorithm (BMSSA) based on an improved bee foraging strategy and an unscented mutation strategy. The improved bee foraging strategy is leveraged in the follower location update phase to break the fixed range search of salp swarm algorithm, while the unscented mutation strategy on the optimal solution is employed to enhance the quality of the optimal solution. Extensive experimental results on public CEC 2014 benchmark functions validate that the proposed BMSSA performs better than nine well-known metaheuristic methods and seven state-of-the-art algorithms. The binary BMSSA (bBMSSA) algorithm is further proposed for feature selection by using BMSSA as the selection strategy and support vector machine as the classifier. Experimental comparisons on 12 UCI datasets demonstrate the superiority of bBMSSA. Finally, we collected a dataset on the return-intentions of overseas Chinese after coronavirus disease (COVID-19) through an anonymous online questionnaire and performed a case study by setting up a bBMSSA-based feature selection optimization model. The outcomes manifest that the bBMSSA-based feature selection model exhibits a conspicuous prowess, attaining an accuracy exceeding 93%. The case study shows that the development prospects, the family and job in the place of residence, seeking opportunities in China, and the possible time to return to China are the critical factors influencing the willingness to return to China after COVID-19.
Ce3+ triggers fenton-like processes in neutral solutions for effective catechol degradation
Xing Chen,Xu Liu,Hai-Bo Wang,Kang-Ping Cui,Rohan Weerasooriya,Shi-Long He,Guang-Hong Li,Jun Pan,Kai Zhou 대한환경공학회 2022 Environmental Engineering Research Vol.27 No.1
Classical Fenton and Fenton-like processes destruct organic pollutants in water non-selectively to complete mineralization. However, the usage of classical Fenton or Fenton-like processes is often limited due to the narrow operational pH window, sludge accumulation, inefficient H₂O₂ and efficiency decline. To overcome these constraints, in this study, we used a homogeneous Fe<SUP>3+</SUP>-Ce<SUP>3+</SUP>-H₂O₂ Fenton-like process to degrade catechol at different experimental conditions. At pH 7, almost 97% of 10 mM catechol can be destructed within 60 min while the degradation by Classical Fenton or Fe<SUP>3+</SUP>-H₂O₂ Fenton-like process only 36.2% and 23.7%. The resultant solution after the degradation contains only traces of cerium ions. The sludge created by the process was extensively characterized by FTIR and XPS spectroscopy to elucidate the fate of cerium ions. Electron spin resonance (ESR) data confirmed •OH as the major free radical in Fe<SUP>3+</SUP>-Ce<SUP>3+</SUP>-H₂O₂ process. Our Fenton-like process widens the optimal pH values to neutral condition.
Qikai Xing,Zhimin Zheng,Xiangui Zhou,Xujun Chen,Zejian Guo 한국식물학회 2015 Journal of Plant Biology Vol.58 No.1
Heading date is one of the most important agronomic traits in rice. Here, we analyzed an early flowering mutant ds9 under long day (LD) conditions and found that the early flowering phenotype was controlled by a single dominant gene. Mapping the Ds9 revealed that it was located near SSR marker RM5432 on chromosome 8, close to the known heading date-related DTH8/Ghd8 locus. Sequence analysis indicated that Ds9 was allelic to Ghd8, encoding the OsHAP3H subunit of CCAAT-box binding proteins (HAPs), and transformation of ds9 mutant with the OsHAP3H gene from wild type XS11 plants significantly increased the heading date under LD conditions. Yeast two hybrid and three hybrid assays revealed that the C-terminus of OsHAP3H is required for its interactions with OsHAP2 and OsHAP5. The data demonstrated that OsHAP3H plays a critical role as a repressor of photoperiodic flowering in rice.